Thiazide-induced hyponatraemia is associated with increased water intake and impaired urea-mediated water excretion at low plasma antidiuretic hormone and urine aquaporin-2

Journal of Hypertension

Volumn 33, Issue 3, 2015, Pages 627-633

  Frenkel, Nanne J ^a   Vogt, Liffert ^a   De Rooij, Sophia E ^a   Trimpert, Christiane ^b   Levi, Marcel M ^a   Deen, Peter M T ^b   Van Den Born, Bert Jan H ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

antidiuretic hormone; aquaporin2; free water excretion; hyponatraemia; thiazide diuretics

Indexed keywords

AMILORIDE; AQUAPORIN 2; HYDROCHLOROTHIAZIDE; SODIUM; UREA; VASOPRESSIN; ELECTROLYTE; THIAZIDE DIURETIC AGENT; VASOPRESSIN DERIVATIVE;

ADULT; AGED; ANTIHYPERTENSIVE THERAPY; ARTICLE; BODY WEIGHT; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; DIURESIS; DIURETIC THERAPY; FEMALE; FLUID BALANCE; FLUID INTAKE; FREE WATER CLEARANCE; HUMAN; HYPERTENSION; HYPONATREMIA; MALE; MEDICAL HISTORY; OSMOREGULATION; PLASMA OSMOLALITY; PREDICTION; PRIORITY JOURNAL; PROTEIN URINE LEVEL; SINGLE DRUG DOSE; SODIUM BLOOD LEVEL; SODIUM RETENTION; SODIUM URINE LEVEL; URINE OSMOLALITY; VASOPRESSIN BLOOD LEVEL; BLOOD; CHEMICALLY INDUCED; DRINKING; DRUG EFFECTS; ELECTROLYTE BALANCE; KIDNEY; METABOLISM; MIDDLE AGED; OSMOLARITY; PHYSIOLOGY; URINE; VERY ELDERLY;

AGED; AGED, 80 AND OVER; AQUAPORIN 2; DRINKING; ELECTROLYTES; FEMALE; HUMANS; HYDROCHLOROTHIAZIDE; HYPERTENSION; HYPONATREMIA; KIDNEY; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; SODIUM; SODIUM CHLORIDE SYMPORTER INHIBITORS; UREA; VASOPRESSINS; WATER-ELECTROLYTE BALANCE;

EID: 84922463771     PISSN: 02636352     EISSN: 14735598     Source Type: Journal    
DOI: 10.1097/HJH.0000000000000423     Document Type: Article

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