Protein Carbonylation and heat shock proteins in human skeletal muscle: Relationships to age and sarcopenia

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 70, Issue 2, 2015, Pages 174-181

  Beltran Valls, Maria R ^a   Wilkinson, Daniel J ^b   Narici, Marco V ^b   Smith, Kenneth ^b   Phillips, Bethan E ^b   Caporossi, Daniela ^a   Atherton, Philip J ^b  

^a UNIVERSITY OF ROME FORO ITALICO   (Italy)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Carbonylation; Heat shock protein; Mitochondria; Sarcopenia

Indexed keywords

ALPHA CRYSTALLIN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70;

ADULT; AGED; AGING; HUMAN; MALE; METABOLISM; MUSCLE MITOCHONDRION; MUSCLE STRENGTH; PATHOPHYSIOLOGY; PHYSIOLOGY; PROTEIN CARBONYLATION; SARCOPENIA; SKELETAL MUSCLE;

ADULT; AGED; AGING; ALPHA-CRYSTALLIN B CHAIN; HSP27 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; MALE; MITOCHONDRIA, MUSCLE; MUSCLE STRENGTH; MUSCLE, SKELETAL; PROTEIN CARBONYLATION; SARCOPENIA;

EID: 84922463601     PISSN: 10795006     EISSN: 1758535X     Source Type: Journal    
DOI: 10.1093/gerona/glu007     Document Type: Article

References (34)

1. Mitchell WK, Williams J, Atherton P, Larvin M, Lund J, Narici M. Sarcopenia, dynapenia, and the impact of advancing age on human skeletal muscle size and strength; a quantitative review. Front Physiol. 2012; 3: 1-18. doi: 10.3389/fphys.2012.00260.
2. Rosenberg I. Summary comments: epidemiological and methodological problems in determining nutritional status of older persons. Am J Clin Nutr. 1989; 50: 1231-3.
3. Fielding RA, Vellas B, Evans WJ, et al. Sarcopenia: an undiagnosed condition in older adults. Current consensus definition: prevalence, etiology, and consequences. International working group on sarcopenia. J Am Med Dir Assoc. 2011; 12: 249-256. doi: 10.1016/j. jamda.2011.01.003.
4. Narici MV, Maffulli N. Sarcopenia: characteristics, mechanisms and functional significance. Br Med Bull. 2010; 95: 139-159. doi: 10.1093/bmb/ldq008.
5. Rennie MJ, Selby A, Atherton P, et al. Facts, noise and wishful thinking: muscle protein turnover in aging and human disuse atrophy. Scand J Med Sci Sports. 2010; 20: 5-9. doi: 10.1111/j.1600-0838.2009.00967.x.
6. Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol. 1956; 11: 298-300.
7. Sies H, Jones DP. Oxidative Stress. Encyclopedia of Stress. Amsterdam, UK: Elsevier; 2007.
8. Beal MF. Oxidatively modified proteins in aging and disease. Free Radic Biol Med. 2002; 32: 797-803.
9. Fulle S, Protasi F, Di Tano G, et al. The contribution of reactive oxygen species to sarcopenia and muscle ageing. Exp Gerontol. 2004; 39: 17-24.
10. Dalle-Donne I, Rossi R, Giustarini D, Milzani A, Colombo R. Protein carbonyl groups as biomarkers of oxidative stress. Clin Chim Acta. 2003; 329: 23-38.
11. Calderwood SK, Murshid A, Prince T. The shock of aging: molecular chaperones and the heat shock response in longevity and aging-a minireview. Gerontology. 2009; 55: 550-558. doi: 10.1159/000225957.
12. Feder ME, Hofmann GE. Heat-shock proteins, molecular chaperones, and the stress response: evolutionary and ecological physiology. Annu Rev Physiol. 1999; 61: 243-282.
13. Kato K, Ito H, Kamei K, Iwamoto I, Inaguma Y. Innervationdependent phosphorylation and accumulation of alphaB-crystallin and Hsp27 as insoluble complexes in disused muscle. FASEB J. 2002; 16: 1432-1434.
14. Ogawa K, Kim HK, Shimizu T, Abe S, Shiga Y, Calderwood SK. Plasma heat shock protein 72 as a biomarker of sarcopenia in elderly people. Cell Stress Chaperon. 2012; 17: 349-359. doi: 10.1007/s12192-011-0310-6.
15. Njemini R, Abeele MV, Demanet C, Lambert M, Vandebosch S, Mets T. Age-related decrease in the inducibility of heat-shock protein 70 in human peripheral blood mononuclear cells. J Clin Immunol. 2002; 22: 195-205.
16. Njemini RM, Lambert M, Demanet C, Mets T. The effect of aging and inflammation on heat shock protein 27 in human monocytes and lymphocytes. Exp Gerontol. 2007; 41: 312-319.
17. Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc. 2002; 50: 889-896.
18. Dietrichson P, Coakley J, Smith PE, Griffiths RD, Helliwell TR, Edwards RH. Conchotome and needle percutaneous biopsy of skeletal muscle. J Neurol Neurosurg Psychiatry. 1987; 50: 1461-1467.
19. Atherton P, Babraj J, Smith K, Singh J. Selective activation of AMPKPGC- 1α or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation. FASEB J. 2005; 23: 1-23.
20. Graham JM. Isolation of mitochondria from tissues and cells by differential centrifugation. Curr Protoc Cell Biol. 2001; 3: 3. doi: 10.1002/0471143030.cb0303s04.
21. Marzani B, Felzani G, Bellomo RG, Vecchiet J, Marzatico F. Human muscle aging: ROS-mediated alterations in rectus abdominis and vastus lateralis muscles. Exp Gerontol. 2005; 40: 959-965.
22. Mecocci P, Fano G, Fulle S, et al. Age-dependent increases in oxidative damage to DNA, lipids, and proteins in human skeletal muscle. Free Radic Biol Med. 1999; 26: 303-308.
23. Pansarasa O, Bertorelli L, Vecchiett J, Felzani G, Marzatico F. Agedependent changes in oxidative damage to DNA, lipids and protein in human skeletal muscle. Free Radic Biol Med. 1999; 27: 617-622.
24. Gianni P, Jan KJ, Douglas MJ, Stuart PM, Tarnopolsky MA. Oxidative stress and the mitochondrial theory of aging in human skeletal muscle. Exp Gerontol. 2004; 39: 1391-1400.
25. Sohal RS, Sohal BH. Hydrogen peroxide release by mitochondria increases during aging. Mech Ageing Dev. 1991; 57: 187-202.
26. Sastre J, Pallardo FV, Vina J. The role of mitochondrial oxidative stress in aging. Free Radic Biol Med. 2003; 35: 1-8.
27. Ghosh S, Lertwattanarak R, Lefort N, et al. Reduction in reactive oxygen species production by mitochondria from elderly subjects with normal and impaired glucose tolerance. Diabetes. 2011; 60: 2051-2060. doi: 10.2337/db11-0121.
28. Gomez-Cabrera MC, Sanchis-Gomar F, Garcia-Valles R, et al. Mitochondria as sources and targets of damage in cellular aging. Clin Chem Lab Med. 2012; 50: 1287-1295. doi: 10.1515/cclm-2011-0795.
29. Rooyackers OE, Adey DB, Ades PA, Nair KS. Effect of age in vivo rates of mitochondrial protein synthesis in human skeletal muscle. Proc Natl Acad Sci USA. 1996; 93: 15634-15369.
30. Fehrenbach E, Northoff H. Free radicals, exercise, apoptosis, and heat shock proteins. Exerc Immunol Rev. 2001; 7: 66-89.
31. Liberek K, Lewandowska A, Zietkiewicz S. Chaperones in control of protein disaggregation. EMBO J. 2008; 27: 328-335. doi: 10.1038/sj.emboj.7601970.
32. Y amaguchi T, Arai H, Katayama N, Ishikawa T, Kikumoto K, Atomi Y. Age-related increase of insoluble, phosphorylated small heat shock proteins in human skeletal muscle. J Gerontol A Biol Sci Med Sci. 2007; 62: 481-489.
33. Thalacker-Mercer AE, Dell'Italia LJ, Cui X, Cross JM, Bamman MM. Differential genomic responses in old vs. young humans despite similar levels of modest muscle damage after resistance loading. Physiol Genomics. 2010; 40: 141-149. doi: 10.1152/physiolgenomics.00151.2009.
34. Soti C, Csermely P. Aging and molecular chaperones. Exp Gerontol. 2003; 38: 1037-1040.