-
1
-
-
73849141006
-
Protein kinases A and C and phosphatidylinositol 3 kinase regulate glycogen synthase kinase-3A serine 21 phosphorylation in boar spermatozoa
-
Bragado MJ, Aparicio IM, Gil MC, Garcia-Marin LJ. Protein kinases A and C and phosphatidylinositol 3 kinase regulate glycogen synthase kinase-3A serine 21 phosphorylation in boar spermatozoa. J Cell Biochem 2010; 109: 65-73.
-
(2010)
J Cell Biochem
, vol.109
, pp. 65-73
-
-
Bragado, M.J.1
Aparicio, I.M.2
Gil, M.C.3
Garcia-marin, L.J.4
-
2
-
-
84862493914
-
AMP-activated protein kinase: new regulation, new roles?
-
Carling D, Thornton C, Woods A, Sanders MJ. AMP-activated protein kinase: new regulation, new roles? Biochem J 2012;445:11-27.
-
(2012)
Biochem J
, vol.445
, pp. 11-27
-
-
Carling, D.1
Thornton, C.2
Woods, A.3
Sanders, M.J.4
-
3
-
-
33744514139
-
Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome
-
Cool B, Zinker B, Chiou W, Kifle L, Cao N, Perham M, Dickinson R, Adler A, Gagne G, Iyengar R et al. Identification and characterization of a small molecule AMPK activator that treats key components of type 2 diabetes and the metabolic syndrome. Cell Metab 2006; 3: 403-416.
-
(2006)
Cell Metab
, vol.3
, pp. 403-416
-
-
Cool, B.1
Zinker, B.2
Chiou, W.3
Kifle, L.4
Cao, N.5
Perham, M.6
Dickinson, R.7
Adler, A.8
Gagne, G.9
Iyengar, R.10
-
5
-
-
29244463866
-
Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells?
-
Evans AM, Mustard KJ, Wyatt CN, Peers C, Dipp M, Kumar P, Kinnear NP, Hardie DG. Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells? J Biol Chem 2005;280:41504-41511.
-
(2005)
J Biol Chem
, vol.280
, pp. 41504-41511
-
-
Evans, A.M.1
Mustard, K.J.2
Wyatt, C.N.3
Peers, C.4
Dipp, M.5
Kumar, P.6
Kinnear, N.P.7
Hardie, D.G.8
-
6
-
-
0034759226
-
Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane
-
Flesch FM, Brouwers JF, Nievelstein PF, Verkleij AJ, van Golde LM, Colenbrander B, Gadella BM. Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane. J Cell Sci 2001; 114: 3543-3555.
-
(2001)
J Cell Sci
, vol.114
, pp. 3543-3555
-
-
Flesch, F.M.1
Brouwers, J.F.2
Nievelstein, P.F.3
Verkleij, A.J.4
van Golde, L.M.5
Colenbrander, B.6
Gadella, B.M.7
-
7
-
-
0034083188
-
The capacitating agent bicarbonate induces protein kinase A-dependent changes in phospholipid transbilayer behavior in the sperm plasma membrane
-
Gadella BM, Harrison RA. The capacitating agent bicarbonate induces protein kinase A-dependent changes in phospholipid transbilayer behavior in the sperm plasma membrane. Development 2000; 127: 2407-2420.
-
(2000)
Development
, vol.127
, pp. 2407-2420
-
-
Gadella, B.M.1
Harrison, R.A.2
-
8
-
-
3543144347
-
Bicarbonate and its role in mammalian sperm function
-
307-319
-
Gadella BM, Van Gestel RA. Bicarbonate and its role in mammalian sperm function. Anim Reprod Sci 2004; 82-83:307-319.
-
(2004)
Anim Reprod Sci
, pp. 82-83
-
-
Gadella, B.M.1
Van Gestel, R.A.2
-
10
-
-
46449122516
-
Adenosine triphosphate production by bovine spermatozoa and its relationship to semen fertilizing ability
-
Garrett LJ, Revell SG, Leese HJ. Adenosine triphosphate production by bovine spermatozoa and its relationship to semen fertilizing ability. J Androl 2008; 29: 449-458.
-
(2008)
J Androl
, vol.29
, pp. 449-458
-
-
Garrett, L.J.1
Revell, S.G.2
Leese, H.J.3
-
11
-
-
36348998521
-
Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase
-
Goransson O, McBride A, Hawley SA, Ross FA, Shpiro N, Foretz M, Viollet B, Hardie DG, Sakamoto K. Mechanism of action of A-769662, a valuable tool for activation of AMP-activated protein kinase. J Biol Chem 2007; 282: 32549-32560.
-
(2007)
J Biol Chem
, vol.282
, pp. 32549-32560
-
-
Goransson, O.1
McBride, A.2
Hawley, S.A.3
Ross, F.A.4
Shpiro, N.5
Foretz, M.6
Viollet, B.7
Hardie, D.G.8
Sakamoto, K.9
-
12
-
-
80053035284
-
AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function
-
Hardie DG. AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function. Genes Dev 2011; 25: 1895-1908.
-
(2011)
Genes Dev
, vol.25
, pp. 1895-1908
-
-
Hardie, D.G.1
-
13
-
-
84883709817
-
AMPK: a target for drugs and natural products with effects on both diabetes and cancer
-
Hardie DG. AMPK: a target for drugs and natural products with effects on both diabetes and cancer. Diabetes 2013; 62: 2164-2172.
-
(2013)
Diabetes
, vol.62
, pp. 2164-2172
-
-
Hardie, D.G.1
-
14
-
-
0942297993
-
Rapid PKA-catalysed phosphorylation of boar sperm proteins induced by the capacitating agent bicarbonate
-
Harrison RA. Rapid PKA-catalysed phosphorylation of boar sperm proteins induced by the capacitating agent bicarbonate. Mol Reprod Dev 2004; 67: 337-352.
-
(2004)
Mol Reprod Dev
, vol.67
, pp. 337-352
-
-
Harrison, R.A.1
-
15
-
-
11144282376
-
Bicarbonate-induced membrane processing in sperm capacitation
-
Harrison RA, Gadella BM. Bicarbonate-induced membrane processing in sperm capacitation. Theriogenology 2005; 63: 342-351.
-
(2005)
Theriogenology
, vol.63
, pp. 342-351
-
-
Harrison, R.A.1
Gadella, B.M.2
-
16
-
-
0020487559
-
Bovine serum albumin, sperm motility, and the 'dilution effect'
-
Harrison RA, Dott HM, Foster GC. Bovine serum albumin, sperm motility, and the 'dilution effect'. J Exp Zool 1982; 222: 81-88.
-
(1982)
J Exp Zool
, vol.222
, pp. 81-88
-
-
Harrison, R.A.1
Dott, H.M.2
Foster, G.C.3
-
17
-
-
23044432463
-
Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
-
Hawley SA, Pan DA, Mustard KJ, Ross L, Bain J, Edelman AM, Frenguelli BG, Hardie DG. Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab 2005; 2: 9-19.
-
(2005)
Cell Metab
, vol.2
, pp. 9-19
-
-
Hawley, S.A.1
Pan, D.A.2
Mustard, K.J.3
Ross, L.4
Bain, J.5
Edelman, A.M.6
Frenguelli, B.G.7
Hardie, D.G.8
-
18
-
-
77956410464
-
Use of cells expressing Y subunit variants to identify diverse mechanisms of AMPK activation
-
Hawley SA, Ross FA, Chevtzoff C, Green KA, Evans A, Fogarty S, Towler MC, Brown LJ, Ogunbayo OA, Evans AM et al. Use of cells expressing Y subunit variants to identify diverse mechanisms of AMPK activation. Cell Metab 2010; 11: 554-565.
-
(2010)
Cell Metab
, vol.11
, pp. 554-565
-
-
Hawley, S.A.1
Ross, F.A.2
Chevtzoff, C.3
Green, K.A.4
Evans, A.5
Fogarty, S.6
Towler, M.C.7
Brown, L.J.8
Ogunbayo, O.A.9
Evans, A.M.10
-
19
-
-
84862264680
-
AMP-activated kinase AMPK is expressed in boar spermatozoa and regulates motility
-
Hurtado de Llera A, Martin-Hidalgo D, Gil MC, Garcia-Marin LJ, Bragado MJ. AMP-activated kinase AMPK is expressed in boar spermatozoa and regulates motility. PLoS One 2012; 7: e38840.
-
(2012)
PLoS One
, vol.7
, pp. e38840
-
-
Hurtado de Llera, A.1
Martin-hidalgo, D.2
Gil, M.C.3
Garcia-marin, L.J.4
Bragado, M.J.5
-
20
-
-
84879215933
-
AMP-activated kinase, AMPK, is involved in the maintenance of plasma membrane organization in boar spermatozoa
-
Hurtado de Llera A, Martin-Hidalgo D, Rodriguez-Gil JE, Gil MC, Garcia-Marin LJ, Bragado MJ. AMP-activated kinase, AMPK, is involved in the maintenance of plasma membrane organization in boar spermatozoa. Biochim Biophys Acta 2013; 1828: 2143-2151.
-
(2013)
Biochim Biophys Acta
, vol.1828
, pp. 2143-2151
-
-
Hurtado de Llera, A.1
Martin-hidalgo, D.2
Rodriguez-gil, J.E.3
Gil, M.C.4
Garcia-marin, L.J.5
Bragado, M.J.6
-
21
-
-
84899969954
-
The calcium/CaMKKalpha/beta and the cAMP/PKA pathways are essential upstream regulators of AMPK activity in boar spermatozoa
-
Hurtado de Llera A, Martin-Hidalgo D, Gil MC, Garcia-Marin LJ, Bragado MJ. The calcium/CaMKKalpha/beta and the cAMP/PKA pathways are essential upstream regulators of AMPK activity in boar spermatozoa. Biol Reprod 2014; 90:29, 1-10.
-
(2014)
Biol Reprod
, vol.90
, Issue.29
, pp. 1-10
-
-
Hurtado de Llera, A.1
Martin-hidalgo, D.2
Gil, M.C.3
Garcia-marin, L.J.4
Bragado, M.J.5
-
22
-
-
81055126243
-
Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability
-
Ikematsu N, Dallas ML, Ross FA, Lewis RW, Rafferty JN, David JA, Suman R, Peers C, Hardie DG, Evans AM. Phosphorylation of the voltage-gated potassium channel Kv2.1 by AMP-activated protein kinase regulates membrane excitability. Proc Natl Acad Sci USA 2011; 108:18132-18137.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, pp. 18132-18137
-
-
Ikematsu, N.1
Dallas, M.L.2
Ross, F.A.3
Lewis, R.W.4
Rafferty, J.N.5
David, J.A.6
Suman, R.7
Peers, C.8
Hardie, D.G.9
Evans, A.M.10
-
23
-
-
33745815985
-
AMP-activated protein kinase signaling in metabolic regulation
-
Long YC, Zierath JR. AMP-activated protein kinase signaling in metabolic regulation. J Clin Invest 2006; 116: 1776-1783.
-
(2006)
J Clin Invest
, vol.116
, pp. 1776-1783
-
-
Long, Y.C.1
Zierath, J.R.2
-
24
-
-
28544447267
-
Phosphatidylserine externalization in human sperm induced by calcium ionophore A23187: relationship with apoptosis, membrane scrambling and the acrosome reaction
-
Martin G, Sabido O, Durand P, Levy R. Phosphatidylserine externalization in human sperm induced by calcium ionophore A23187: relationship with apoptosis, membrane scrambling and the acrosome reaction. Hum Reprod 2005; 20: 3459-3468.
-
(2005)
Hum Reprod
, vol.20
, pp. 3459-3468
-
-
Martin, G.1
Sabido, O.2
Durand, P.3
Levy, R.4
-
25
-
-
79953274844
-
The effect of melatonin on the quality of extended boar semen after long-term storage at 17 degrees C
-
Martin-Hidalgo D, Baron FJ, Bragado MJ, Carmona P, Robina A, Garcia-Marin LJ, Gil MC. The effect of melatonin on the quality of extended boar semen after long-term storage at 17 degrees C. Theriogenology 2011; 75: 1550-1560.
-
(2011)
Theriogenology
, vol.75
, pp. 1550-1560
-
-
Martin-hidalgo, D.1
Baron, F.J.2
Bragado, M.J.3
Carmona, P.4
Robina, A.5
Garcia-marin, L.J.6
Gil, M.C.7
-
26
-
-
84881369573
-
Adenosine monophosphate-activated kinase, AMPK, is involved in the maintenance of the quality of extended boar semen during long-term storage
-
Martin-Hidalgo D, Hurtado de LA, Yeste M, Gil MC, Bragado MJ, Garcia-Marin LJ. Adenosine monophosphate-activated kinase, AMPK, is involved in the maintenance of the quality of extended boar semen during long-term storage. Theriogenology 2013; 80: 285-294.
-
(2013)
Theriogenology
, vol.80
, pp. 285-294
-
-
Martin-hidalgo, D.1
Hurtado de, L.A.2
Yeste, M.3
Gil, M.C.4
Bragado, M.J.5
Garcia-marin, L.J.6
-
27
-
-
34547852044
-
Energy metabolism and sperm function
-
Miki K. Energy metabolism and sperm function. Soc Reprod Fertil Suppl 2007; 65: 309-325.
-
(2007)
Soc Reprod Fertil Suppl
, vol.65
, pp. 309-325
-
-
Miki, K.1
-
28
-
-
84905757105
-
Metformin-mode of action and clinical implications for diabetes and cancer
-
Pernicova I, Korbonits M. Metformin-mode of action and clinical implications for diabetes and cancer. Nat Rev Endocrinol 2014; 10: 143-156.
-
(2014)
Nat Rev Endocrinol
, vol.10
, pp. 143-156
-
-
Pernicova, I.1
Korbonits, M.2
-
29
-
-
84896110819
-
Metformin: a metabolic disruptor and anti-diabetic drug to target human leukemia
-
Rosilio C, Ben-Sahra I, Bost F, Peyron JF. Metformin: a metabolic disruptor and anti-diabetic drug to target human leukemia. Cancer Lett 2014; 346: 188-196.
-
(2014)
Cancer Lett
, vol.346
, pp. 188-196
-
-
Rosilio, C.1
Ben-sahra, I.2
Bost, F.3
Peyron, J.F.4
-
30
-
-
36348978499
-
Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family
-
Sanders MJ, Ali ZS, Hegarty BD, Heath R, Snowden MA, Carling D. Defining the mechanism of activation of AMP-activated protein kinase by the small molecule A-769662, a member of the thienopyridone family. J Biol Chem 2007; 282: 32539-32548.
-
(2007)
J Biol Chem
, vol.282
, pp. 32539-32548
-
-
Sanders, M.J.1
Ali, Z.S.2
Hegarty, B.D.3
Heath, R.4
Snowden, M.A.5
Carling, D.6
-
31
-
-
85047691317
-
CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations
-
Scott JW, Hawley SA, Green KA, Anis M, Stewart G, Scullion GA, Norman DG, Hardie DG. CBS domains form energy-sensing modules whose binding of adenosine ligands is disrupted by disease mutations. J Clin Invest 2004; 113: 274-284.
-
(2004)
J Clin Invest
, vol.113
, pp. 274-284
-
-
Scott, J.W.1
Hawley, S.A.2
Green, K.A.3
Anis, M.4
Stewart, G.5
Scullion, G.A.6
Norman, D.G.7
Hardie, D.G.8
-
32
-
-
33845949733
-
Dissecting the role of 5-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase
-
Suter M, Riek U, Tuerk R, Schlattner U, Wallimann T, Neumann D. Dissecting the role of 5-AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase. J Biol Chem 2006; 281: 32207-32216.
-
(2006)
J Biol Chem
, vol.281
, pp. 32207-32216
-
-
Suter, M.1
Riek, U.2
Tuerk, R.3
Schlattner, U.4
Wallimann, T.5
Neumann, D.6
-
33
-
-
84862740215
-
Inactivation of AMPKalpha1 induces asthenozoospermia and alters spermatozoa morphology
-
Tartarin P, Guibert E, Toure A, Ouiste C, Leclerc J, Sanz N, Briere S, Dacheux JL, Delaleu B, McNeilly JR et al. Inactivation of AMPKalpha1 induces asthenozoospermia and alters spermatozoa morphology. Endocrinology 2012; 153: 3468-3481.
-
(2012)
Endocrinology
, vol.153
, pp. 3468-3481
-
-
Tartarin, P.1
Guibert, E.2
Toure, A.3
Ouiste, C.4
Leclerc, J.5
Sanz, N.6
Briere, S.7
Dacheux, J.L.8
Delaleu, B.9
McNeilly, J.R.10
-
34
-
-
56049117647
-
A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis
-
Towler MC, Fogarty S, Hawley SA, Pan DA, Martin DM, Morrice NA, McCarthy A, Galardo MN, Meroni SB, Cigorraga SB et al. A novel short splice variant of the tumour suppressor LKB1 is required for spermiogenesis. Biochem J 2008; 416: 1-14.
-
(2008)
Biochem J
, vol.416
, pp. 1-14
-
-
Towler, M.C.1
Fogarty, S.2
Hawley, S.A.3
Pan, D.A.4
Martin, D.M.5
Morrice, N.A.6
McCarthy, A.7
Galardo, M.N.8
Meroni, S.B.9
Cigorraga, S.B.10
-
35
-
-
0033570112
-
Cholesterol efflux-mediated signal transduction in mammalian sperm: cholesterol release signals an increase in protein tyrosine phosphorylation during mouse sperm capacitation
-
Visconti PE, Ning X, Fornés MW, Alvarez JG, Stein P, Connors SA, Kopf GS. Cholesterol efflux-mediated signal transduction in mammalian sperm: cholesterol release signals an increase in protein tyrosine phosphorylation during mouse sperm capacitation. Dev Biol 1999; 214: 429-443.
-
(1999)
Dev Biol
, vol.214
, pp. 429-443
-
-
Visconti, P.E.1
Ning, X.2
Fornés, M.W.3
Alvarez, J.G.4
Stein, P.5
Connors, S.A.6
Kopf, G.S.7
-
36
-
-
7044222467
-
Effects of in vitro storage time and semen-extender on membrane quality of boar sperm assessed by flow cytometry
-
Waterhouse KE, De Angelis PM, Haugan T, Paulenz H, Hofmo PO, Farstad W. Effects of in vitro storage time and semen-extender on membrane quality of boar sperm assessed by flow cytometry. Theriogenology 2004; 62: 1638-1651.
-
(2004)
Theriogenology
, vol.62
, pp. 1638-1651
-
-
Waterhouse, K.E.1
De Angelis, P.M.2
Haugan, T.3
Paulenz, H.4
Hofmo, P.O.5
Farstad, W.6
-
37
-
-
10744230065
-
LKB1 is the upstream kinase in the AMP-activated protein kinase cascade
-
Woods A, Johnstone SR, Dickerson K, Leiper FC, Fryer LG, Neumann D, Schlattner U, Wallimann T, Carlson M, Carling D. LKB1 is the upstream kinase in the AMP-activated protein kinase cascade. Curr Biol 2003; 13: 2004-2008.
-
(2003)
Curr Biol
, vol.13
, pp. 2004-2008
-
-
Woods, A.1
Johnstone, S.R.2
Dickerson, K.3
Leiper, F.C.4
Fryer, L.G.5
Neumann, D.6
Schlattner, U.7
Wallimann, T.8
Carlson, M.9
Carling, D.10
-
38
-
-
33751229931
-
A pivotal role for endogenous TGF- beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway
-
Xie M, Zhang D, Dyck JR, Li Y, Zhang H, Morishima M, Mann DL, Taffet GE, Baldini A, Khoury DS et al. A pivotal role for endogenous TGF- beta-activated kinase-1 in the LKB1/AMP-activated protein kinase energy-sensor pathway. Proc Natl Acad Sci USA 2006; 103: 17378-17383.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 17378-17383
-
-
Xie, M.1
Zhang, D.2
Dyck, J.R.3
Li, Y.4
Zhang, H.5
Morishima, M.6
Mann, D.L.7
Taffet, G.E.8
Baldini, A.9
Khoury, D.S.10
-
39
-
-
46049103347
-
Targeted deletion of Tssk1 and 2 causes male infertility due to haploinsufficiency
-
Xu B, Hao Z, Jha KN, Zhang Z, Urekar C, Digilio L, Pulido S, Strauss JF III, Flickinger CJ, Herr JC. Targeted deletion of Tssk1 and 2 causes male infertility due to haploinsufficiency. Dev Biol 2008; 319: 211-222.
-
(2008)
Dev Biol
, vol.319
, pp. 211-222
-
-
Xu, B.1
Hao, Z.2
Jha, K.N.3
Zhang, Z.4
Urekar, C.5
Digilio, L.6
Pulido, S.7
Strauss, J.F.8
Flickinger, C.J.9
Herr, J.C.10
|