High-sensitivity C-reactive protein complements plasma Epstein-Barr virus deoxyribonucleic acid prognostication in nasopharyngeal carcinoma: A large-scale retrospective and prospective cohort study

International Journal of Radiation Oncology Biology Physics

Volumn 91, Issue 2, 2015, Pages 325-336

  Tang, Lin Quan ^a,b   Li, Chao Feng ^a,b   Chen, Qiu Yan ^a,b   Zhang, Lu ^a,b   Lai, Xiao Ping ^c   He, Yun ^c   Xu, Yun Xiu Xiu ^c   Hu, Dong Peng ^c   Wen, Shi Hua ^c   Peng, Yu Tuan ^c   Chen, Wen Hui ^a   Liu, Huai ^a,b   Guo, Shan Shan ^a,b   Liu, Li Ting ^a,b   Li, Jing ^a   Zhang, Jing Ping ^a,b   Guo, Ling ^a,b   Zhao, Chong ^a,b   Cao, Ka Jia ^a,b   Qian, Chao Nan ^a,b   Zeng, Yi Xin ^a   Guo, Xiang ^a,b   Mai, Hai Qiang ^a,b   Zeng, Mu Sheng ^a   more..

^a SUN YAT SEN UNIVERSITY CANCER CENTER   (China)

^b SUN YAT SEN UNIVERSITY   (China)

^c SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MULTIVARIANT ANALYSIS; PATHOLOGY; PROTEINS; VIRUSES;

C-REACTIVE PROTEINS; CARDIO-VASCULAR DISEASE; DISEASE FREE SURVIVAL; DISTANT METASTASIS; EPSTEIN-BARR VIRUS; MULTI VARIATE ANALYSIS; NASOPHARYNGEAL CARCINOMA; SURVIVAL PROBABILITIES;

NUCLEIC ACIDS;

C REACTIVE PROTEIN; LACTATE DEHYDROGENASE; VIRUS DNA; TUMOR MARKER;

ADULT; AREA UNDER THE CURVE; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CARDIOVASCULAR DISEASE; CHEMORADIOTHERAPY; CHRONIC HEPATITIS; COHORT ANALYSIS; CORRELATION ANALYSIS; DIABETES MELLITUS; DISEASE FREE SURVIVAL; DISTANT METASTASIS FREE SURVIVAL; EPSTEIN BARR VIRUS; FEMALE; HIGH RISK POPULATION; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LACTATE DEHYDROGENASE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NASOPHARYNX CARCINOMA; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; PROSPECTIVE STUDY; RECEIVER OPERATING CHARACTERISTIC; RETROSPECTIVE STUDY; SURVIVAL RATE; BLOOD; CHINA; CONTROLLED STUDY; EPIDEMIOLOGY; GENETICS; ISOLATION AND PURIFICATION; MORTALITY; NASOPHARYNGEAL NEOPLASMS; PROGNOSIS; RANDOMIZED CONTROLLED TRIAL; REPRODUCIBILITY; RISK FACTOR; SENSITIVITY AND SPECIFICITY;

C-REACTIVE PROTEIN; CHINA; DISEASE-FREE SURVIVAL; DNA, VIRAL; FEMALE; HERPESVIRUS 4, HUMAN; HUMANS; MALE; MIDDLE AGED; NASOPHARYNGEAL NEOPLASMS; PROGNOSIS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; RETROSPECTIVE STUDIES; RISK FACTORS; SENSITIVITY AND SPECIFICITY; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 84922455796     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2014.10.005     Document Type: Article

References (31)

1. Wee JT, Ha TC, Loong SL, et al. Is nasopharyngeal cancer really a "Cantonese cancer"? Chin J Cancer 2010;29:517-526.
2. Ferlay J, Soerjomataram I, Ervik M, et al. GLOBOCAN 2012 v1.0, Cancer Incidence and Mortality Worldwide: IARC Cancer Base No. 11. Lyon, France: International Agency for Research on Cancer; 2013.
3. Wei WI, Sham JS. Nasopharyngeal carcinoma. Lancet 2005;365:2041-2054.
4. Ludwig JA, Weinstein JN. Biomarkers in cancer staging, prognosis and treatment selection. Nat Rev Cancer 2005;5:845-856.
5. Chan AT, Lo YM, Zee B, et al. Plasma Epstein-Barr virus DNA and residual disease after radiotherapy for undifferentiated nasopharyngeal carcinoma. J Natl Cancer Inst 2002;94:1614-1619.
6. Leung SF, Chan AT, Zee B, et al. Pretherapy quantitative measurement of circulating Epstein-Barr virus DNA is predictive of posttherapy distant failure in patients with early-stage nasopharyngeal carcinoma of undifferentiated type. Cancer 2003;98:288-291.
7. Leung SF, Zee B, Ma BB, et al. Plasma Epstein-Barr viral deoxyribonucleic acid quantitation complements tumor-node-metastasis staging prognostication in nasopharyngeal carcinoma. J Clin Oncol 2006;24:5414-5418.
8. Lin JC, Wang WY, Chen KY, et al. Quantification of plasma Epstein-Barr virus DNA in patients with advanced nasopharyngeal carcinoma. N Engl J Med 2004;350:2461-2470.
9. Lo YM, Chan LY, Lo KW, et al. Quantitative analysis of cell-free Epstein-Barr virus DNA in plasma of patients with nasopharyngeal carcinoma. Cancer Res 1999;59:1188-1191.
10. Burtis CA, Ashwood ER, Bruns DE. Tietz Textbook of Clinical Chemistry and Molecular Diagnostics. New York: Elsevier Saunders; 2006.
11. Pepys MB, Hirschfield GM. C-reactive protein: A critical update. J Clin Invest 2003;111:1805-1812.
12. Crumley AB, McMillan DC, McKernan M, et al. An elevated C-reactive protein concentration, prior to surgery, predicts poor cancer-specific survival in patients undergoing resection for gastrooesophageal cancer. Br J Cancer 2006;94:1568-1571.
13. McMillan DC, Canna K, McArdle CS. Systemic inflammatory response predicts survival following curative resection of colorectal cancer. Br J Surg 2003;90:215-219.
14. Scott HR, McMillan DC, Forrest LM, et al. The systemic inflammatory response, weight loss, performance status and survival in patients with inoperable non-small cell lung cancer. Br J Cancer 2002;87:264-267.
15. Allin KH, Bojesen SE, Nordestgaard BG. Baseline C-reactive protein is associated with incident cancer and survival in patients with cancer. J Clin Oncol 2009;27:2217-2224.
16. Li XJ, Peng LX, Shao JY, et al. As an independent unfavorable prognostic factor, IL-8 promotes metastasis of nasopharyngeal carcinoma through induction of epithelial-mesenchymal transition and activation of akt signaling. Carcinogenesis 2012;33:1302-1309.
17. Gourzones C, Barjon C, Busson P. Host-tumor interactions in nasopharyngeal carcinomas. Semin Cancer Biol 2012;22:127-136.
18. Xia WX, Zhang HB, Shi JL, et al. A prognostic model predicts the risk of distant metastasis and death for patients with nasopharyngeal carcinoma based on pre-treatment serum C-reactive protein and N-classification. Eur J Cancer 2013;49:2152-2160.
19. Allin KH, Nordestgaard BG. Elevated C-reactive protein in the diagnosis, prognosis, and cause of cancer. Crit Rev Clin Lab Sci 2011;48:155-170.
20. Pearson TA, Mensah GA, Alexander RW, et al. Markers of inflammation and cardiovascular disease: Application to clinical and public health practice: A statement for healthcare professionals from the Centers for Disease Control and Prevention and the American Heart Association. Circulation 2003;107:499-511.
21. Shao JY, Zhang Y, Li YH, et al. Comparison of Epstein-Barr virus DNA level in plasma, peripheral blood cell and tumor tissue in nasopharyngeal carcinoma. Anticancer Res 2004;24:4059-4066.
22. Fan H, Nicholls J, Chua D, et al. Laboratory markers of tumor burden in nasopharyngeal carcinoma: A comparison of viral load and serologic tests for Epstein-Barr virus. Int J Cancer 2004;112:1036-1041.
23. Ma BB, King A, Lo YM, et al. Relationship between pretreatment level of plasma Epstein-Barr virus DNA, tumor burden, and metabolic activity in advanced nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys 2006;66:714-720.
24. Lo YM, Leung SF, Chan LY, et al. Plasma cell-free Epstein-Barr virus DNA quantitation in patients with nasopharyngeal carcinoma. Correlation with clinical staging. Ann N Y Acad Sci 2000;906:99-101.
25. Lo YM, Chan LY, Chan AT, et al. Quantitative and temporal correlation between circulating cell-free Epstein-Barr virus DNA and tumor recurrence in nasopharyngeal carcinoma. Cancer Res 1999;59:5452-5455.
26. Blann AD, Byrne GJ, Baildam AD. Increased soluble intercellular adhesion molecule-1, breast cancer and the acute phase response. Blood Coagul Fibrinolysis 2002;13:165-168.
27. Chan KC, Zhang J, Chan AT, et al. Molecular characterization of circulating EBV DNA in the plasma of nasopharyngeal carcinoma and lymphoma patients. Cancer Res 2003;63:2028-2032.
28. Mutirangura A, Pornthanakasem W, Theamboonlers A, et al. Epstein-Barr viral DNA in serum of patients with nasopharyngeal carcinoma. Clin Cancer Res 1998;4:665-669.
29. Musani SK, Vasan RS, Bidulescu A, et al. Aldosterone, C-reactive protein, and plasma B-type natriuretic peptide are associated with the development of metabolic syndrome and longitudinal changes in metabolic syndrome components: Findings from the Jackson Heart Study. Diabetes Care 2013;36:3084-3092.
30. Yuan LY, Ke ZQ, Wang M, et al. Procalcitonin and C-reactive protein in the diagnosis and prediction of spontaneous bacterial peritonitis associated with chronic severe hepatitis B. Ann Lab Med 2013;33:449-454.
31. Kam MK, Teo PM, Chau RM, et al. Treatment of nasopharyngeal carcinoma with intensity-modulated radiotherapy: The Hong Kong experience. Int J Radiat Oncol Biol Phys 2004;60:1440-1450.