Post-transplantation hepatocellular carcinoma recurrence: Patterns and relation between vascularity and differentiation degree

World Journal of Hepatology

Volumn 7, Issue 2, 2015, Pages 276-284

  Pecchi, Annarita ^a   Besutti, Giulia ^a   de Santis, Mario ^a   del Giovane, Cinzia ^b   Nosseir, Sofia ^b   Tarantino, Giuseppe ^b   Di Benedetto, Fabrizio ^b   Torricelli, Pietro ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Cell differentiation; Contrast media; Hepatocellular carcinoma; Liver transplantation; Recurrence

Indexed keywords

EID: 84922447696     PISSN: None     EISSN: 19485182     Source Type: Journal    
DOI: 10.4254/wjh.v7.i2.276     Document Type: Article

References (23)

1. Ayuso C, Rimola J, García-Criado A. Imaging of HCC. Abdom Imaging 2012; 37: 215-230 [PMID: 21909721 DOI: 10.1007/s00261-011-9794-x]
2. Shanbhogue AK, Prasad SR, Takahashi N, Vikram R, Sahani DV. Recent advances in cytogenetics and molecular biology of adult hepatocellular tumors: implications for imaging and management. Radiology 2011; 258: 673-693 [PMID: 21339346 DOI: 10.1148/radiol.10100376]
3. Trevisani F, Cantarini MC, Wands JR, Bernardi M. Recent advances in the natural history of hepatocellular carcinoma. Carcinogenesis 2008; 29: 1299-1305 [PMID: 18515282 DOI: 10.1093/carcin/bgn113]
4. Ishak KG, Anthony PP, Sobin LH. Histological typing of tumors of the liver. World Health Organization, Geneva. Available from: URL: http://whqlibdoc.who.int/publications/1994/3540581545_eng.pdf
5. Bolondi L, Gaiani S, Celli N, Golfieri R, Grigioni WF, Leoni S, Venturi AM, Piscaglia F. Characterization of small nodules in cirrhosis by assessment of vascularity: the problem of hypovascular hepatocellular carcinoma. Hepatology 2005; 42: 27-34 [PMID: 15954118]
6. Tarhan NC, Hatipoğlu T, Ercan E, Bener M, Keleş G, Başaran C, Bilezikçi B. Correlation of dynamic multidetector CT findings with pathological grades of hepatocellular carcinoma. Diagn Interv Radiol 2011; 17: 328-333 [PMID: 21328198 DOI: 10.4261/1305-3825. DIR.2682-09.3]
7. Yoon SH, Lee JM, So YH, Hong SH, Kim SJ, Han JK, Choi BI. Multiphasic MDCT enhancement pattern of hepatocellular carcinoma smaller than 3 cm in diameter: tumor size and cellular differentiation. AJR Am J Roentgenol 2009; 193: W482-W489 [PMID: 19933622 DOI: 10.2214/AJR.08.1818]
8. Asayama Y, Yoshimitsu K, Nishihara Y, Irie H, Aishima S, Taketomi A, Honda H. Arterial blood supply of hepatocellular carcinoma and histologic grading: radiologic-pathologic correlation. AJR Am J Roentgenol 2008; 190: W28-W34 [PMID: 18094269]
9. Jang HJ, Kim TK, Burns PN, Wilson SR. Enhancement patterns of hepatocellular carcinoma at contrast-enhanced US: comparison with histologic differentiation. Radiology 2007; 244: 898-906 [PMID: 17709836]
10. Lee JH, Lee JM, Kim SJ, Baek JH, Yun SH, Kim KW, Han JK, Choi BI. Enhancement patterns of hepatocellular carcinomas on multiphasicmultidetector row CT: comparison with pathological differentiation. Br J Radiol 2012; 85: e573-e583 [PMID: 22919011 DOI: 10.1259/bjr/86767895]
11. Mazzaferro V, Regalia E, Doci R, Andreola S, Pulvirenti A, Bozzetti F, Montalto F, Ammatuna M, Morabito A, Gennari L. Liver transplantation for the treatment of small hepatocellular carcinomas in patients with cirrhosis. N Engl J Med 1996; 334: 693-699 [PMID: 8594428]
12. Kim YS, Lim HK, Rhim H, Lee WJ, Joh JW, Park CK. Recurrence of hepatocellular carcinoma after liver transplantation: patterns and prognostic factors based on clinical and radiologic features. AJR Am J Roentgenol 2007; 189: 352-358 [PMID: 17646461]
13. Lee CH, Brubaker LM, Gerber DA, Ku YM, Kim YH, Shin SS, Semelka RC. MRI findings of recurrent hepatocellular carcinoma after liver transplantation: preliminary results. J Magn Reson Imaging 2011; 33: 1399-1405 [PMID: 21591009 DOI: 10.1002/jmri.22326]
14. Chok KS, Chan SC, Cheung TT, Chan AC, Fan ST, Lo CM. Late recurrence of hepatocellular carcinoma after liver transplantation. World J Surg 2011; 35: 2058-2062 [PMID: 21597889 DOI: 10.1007/s00268-011-1146-z]
15. Chan KM, Chou HS, Wu TJ, Lee CF, Yu MC, Lee WC. Characterization of hepatocellular carcinoma recurrence after liver transplantation: perioperative prognostic factors, patterns, and outcome. Asian J Surg 2011; 34: 128-134 [PMID: 22208688 DOI: 10.1016/j.asjsur.2011.08.005]
16. Roayaie S, Schwartz JD, Sung MW, Emre SH, Miller CM, Gondolesi GE, Krieger NR, Schwartz ME. Recurrence of hepatocellular carcinoma after liver transplant: patterns and prognosis. Liver Transpl 2004; 10: 534-540 [PMID: 15048797]
17. Bruix J, Sherman M. Management of hepatocellular carcinoma. Hepatology 2005; 42: 1208-1236 [PMID: 16250051]
18. Nakashima Y, Nakashima O, Hsia CC, Kojiro M, Tabor E. Vascularization of small hepatocellular carcinomas: correlation with differentiation. Liver 1999; 19: 12-18 [PMID: 9928760]
19. Kawamura Y, Ikeda K, Seko Y, Hosaka T, Kobayashi M, Saitoh S, Kumada H. Heterogeneous type 4 enhancement of hepatocellular carcinoma on dynamic CT is associated with tumor recurrence after radiofrequency ablation. AJR Am J Roentgenol 2011; 197: W665-W673 [PMID: 21940538 DOI: 10.2214/AJR.11.6843]
20. Choi JW, Lee JM, Kim SJ, Yoon JH, Baek JH, Han JK, Choi BI. Hepatocellular carcinoma: imaging patterns on gadoxetic acidenhanced MR Images and their value as an imaging biomarker. Radiology 2013; 267: 776-786 [PMID: 23401584 DOI: 10.1148/radiol.13120775]
21. Chung GE, Lee JH, Yoon JH, Myung SJ, Lee K, Jang JJ, Lee JM, Kim SH, Suh KS, Kim YJ, Lee HS. Prognostic implications of tumor vascularity and its relationship to cytokeratin 19 expression in patients with hepatocellular carcinoma. Abdom Imaging 2012; 37: 439-446 [PMID: 21584634 DOI: 10.1007/s00261-011-9756-3]
22. Okamoto D, Yoshimitsu K, Nishie A, Tajima T, Asayama Y, Ishigami K, Hirakawa M, Ushijima Y, Kakihara D, Nakayama T, Nishihara Y, Aishima S, Taketomi A, Kishimoto J, Honda H. Enhancement pattern analysis of hypervascular hepatocellular carcinoma on dynamic MR imaging with histopathological correlation: validity of portal phase imaging for predicting tumor grade. Eur J Radiol 2012; 81: 1116-1121 [PMID: 21420813 DOI: 10.1016/j.ejrad.2011.02.056]
23. Navasa M, Feu F, García-Pagán JC, Jiménez W, Llach J, Rimola A, Bosch J, Rodés J. Hemodynamic and humoral changes after liver transplantation in patients with cirrhosis. Hepatology 1993; 17: 355-360 [PMID: 8444409]