Rapidly polymerizing injectable click hydrogel therapy to delay bone growth in a murine re-synostosis model

Biomaterials

Volumn 35, Issue 36, 2014, Pages 9698-9708

  Hermann, Christopher D ^a,b   Wilson, David S ^a   Lawrence, Kelsey A ^a   Ning, Xinghai ^a   Olivares Navarrete, Rene ^c   Williams, Joseph K ^d   Guldberg, Robert E ^e   Murthy, Niren ^f   Schwartz, Zvi ^f   Boyan, Barbara D ^a,c  

^a GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Virginia Commonwealth University   (United States)

^d CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^e GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^f University of California at Berkeley   (United States)

Author keywords

BMP (bone morphogenetic protein); Bone ingrowth; Craniosynostosis; Hydrogel; Re synostosis

Indexed keywords

BONE; POLYETHYLENE GLYCOLS; PROTEINS; SURGERY;

BMP (BONE MORPHOGENETIC PROTEIN); BONE INGROWTH; BONE MORPHOGENETIC PROTEINS; CRANIOSYNOSTOSIS; DELIVERY VEHICLE; INJECTABLE HYDROGELS; INTRA-CRANIAL PRESSURE; SURGICAL INTERVENTIONS;

HYDROGELS;

BONE MORPHOGENETIC PROTEIN; GREMLIN1; MACROGOL; PROTEIN DERIVATIVE; UNCLASSIFIED DRUG; COPPER; DRUG CARRIER; GREM1 PROTEIN, MOUSE; HYDROGEL; MACROGOL DERIVATIVE; SIGNAL PEPTIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE GROWTH; CLICK CHEMISTRY; CONTROLLED STUDY; CRANIOFACIAL SYNOSTOSIS; CROSS LINKING; ENCAPSULATION; GELATION; HYDROGEL; MACROMOLECULE; MALE; MOUSE; NONHUMAN; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN SECRETION; ANIMAL; BONE DEVELOPMENT; C57BL MOUSE; CHEMISTRY; CRANIOSYNOSTOSES; DRUG EFFECTS; INJECTION; PATHOLOGY;

MURINAE;

ANIMALS; BONE DEVELOPMENT; CLICK CHEMISTRY; COPPER; CRANIOSYNOSTOSES; DRUG CARRIERS; HYDROGEL; INJECTIONS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MALE; MICE; MICE, INBRED C57BL; POLYETHYLENE GLYCOLS; POLYMERIZATION;

EID: 84922382464     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.07.065     Document Type: Article

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