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Volumn 60, Issue 4, 2015, Pages 557-563

Persistence of neisseria gonorrhoeae DNA following treatment for pharyngeal and rectal gonorrhea is influenced by antibiotic susceptibility and reinfection

Author keywords

gonorrhea; minimum inhibitory concentration of antibiotics; persistent DNA on NAAT testing; reinfection; test of cure

Indexed keywords

ANTIINFECTIVE AGENT; AZITHROMYCIN; CEFTRIAXONE; DNA; OPA PROTEIN, NEISSERIA; OUTER MEMBRANE PROTEIN; PORIN; PORIN PROTEIN, NEISSERIA;

EID: 84922381203     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciu873     Document Type: Article
Times cited : (31)

References (37)
  • 1
    • 84858139266 scopus 로고    scopus 로고
    • World Health Organization/United Nations Children's Fund Progress report November 2011 Accessed 10 March 2014 Available at
    • World Health Organization/United Nations Children's Fund. Global HIV/AIDS response: epidemic update and health sector progress towards universal access. Progress report November 2011. Available at: http://www.who.int/hiv/pub/progress-report2011/en/index.html. Accessed 10 March 2014.
    • Global HIV/AIDS Response: Epidemic Update and Health Sector Progress Towards Universal Access
  • 2
    • 33750683395 scopus 로고    scopus 로고
    • Prevalence and incidence of pharyngeal gonorrhea in a longitudinal sample of men who have sex with men: The EXPLORE study
    • Morris SR, Klausner JD, Buchbinder SP, et al. Prevalence and incidence of pharyngeal gonorrhea in a longitudinal sample of men who have sex with men: the EXPLORE study. Clin Infect Dis 2006; 43:1284-9.
    • (2006) Clin Infect Dis , vol.43 , pp. 1284-1289
    • Morris, S.R.1    Klausner, J.D.2    Buchbinder, S.P.3
  • 3
    • 72049121868 scopus 로고    scopus 로고
    • Pharyngeal gonorrhea: An important reservoir of infection?
    • Weinstock H, Workowski KA. Pharyngeal gonorrhea: an important reservoir of infection?. Clin Infect Dis 2009; 49:1798-800.
    • (2009) Clin Infect Dis , vol.49 , pp. 1798-1800
    • Weinstock, H.1    Workowski, K.A.2
  • 4
    • 84894059217 scopus 로고    scopus 로고
    • Molecular approaches to enhance surveillance of gonococcal antimicrobial resistance
    • Goire N, Lahra MM, Chen M, et al. Molecular approaches to enhance surveillance of gonococcal antimicrobial resistance. Nat Rev Microbiol 2014; 12:223-9.
    • (2014) Nat Rev Microbiol , vol.12 , pp. 223-229
    • Goire, N.1    Lahra, M.M.2    Chen, M.3
  • 5
    • 80054750360 scopus 로고    scopus 로고
    • UK national guideline for the management of gonorrhoea in adults
    • Bignell C, Fitzgerald M. UK national guideline for the management of gonorrhoea in adults. Int J STD AIDS 2011; 22:541-7.
    • (2011) Int J STD AIDS , vol.22 , pp. 541-547
    • Bignell, C.1    Fitzgerald, M.2
  • 6
    • 84870891391 scopus 로고    scopus 로고
    • Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea
    • Unemo M, Nicholas RA. Emergence of multidrug-resistant, extensively drug-resistant and untreatable gonorrhea. Future Microbiol 2013; 7:1401-22.
    • (2013) Future Microbiol , vol.7 , pp. 1401-1422
    • Unemo, M.1    Nicholas, R.A.2
  • 7
    • 77149144117 scopus 로고    scopus 로고
    • Spread of a chromosomal cefixime-resistant penA gene among different Neisseria gonorrhoeae lineages
    • Ohnishi M, Watanabe Y, Ono E, et al. Spread of a chromosomal cefixime-resistant penA gene among different Neisseria gonorrhoeae lineages. Antimicrob Agents Chemother 2009; 54:1060-7.
    • (2009) Antimicrob Agents Chemother , vol.54 , pp. 1060-1067
    • Ohnishi, M.1    Watanabe, Y.2    Ono, E.3
  • 9
    • 34248193358 scopus 로고    scopus 로고
    • Incidence and risk factors for urethral and anal gonorrhoea and chlamydia in a cohort of HIV-negative homosexual men: The Health in Men Study
    • Jin F, Prestage GP, Mao L, et al. Incidence and risk factors for urethral and anal gonorrhoea and chlamydia in a cohort of HIV-negative homosexual men: the Health in Men Study. Sex Transm Infect 2007; 83: 113-9.
    • (2007) Sex Transm Infect , vol.83 , pp. 113-119
    • Jin, F.1    Prestage, G.P.2    Mao, L.3
  • 10
    • 78650626559 scopus 로고    scopus 로고
    • Centers for Disease Control and Prevention Sexually transmitted diseases treatment guidelines 2010
    • Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines. 2010. MMWR Recomm Rep 2010; 59(RR-12):1-110.
    • (2010) MMWR Recomm Rep , vol.59 , Issue.RR-12 , pp. 1-110
  • 12
    • 84900535391 scopus 로고    scopus 로고
    • Recommendations for the laboratory-based detection of Chlamydia trachomatis and Neisseria gonorrhoeae-2014
    • Centers for Disease Control and Prevention
    • Centers for Disease Control and Prevention. Recommendations for the laboratory-based detection of Chlamydia trachomatis and Neisseria gonorrhoeae-2014. MMWR Recomm Rep 2014; 63(RR-02): 1-19.
    • (2014) MMWR Recomm Rep , vol.63 , Issue.RR-02 , pp. 1-19
  • 13
    • 50649083124 scopus 로고    scopus 로고
    • Nucleic acid amplification tests in the diagnosis of chlamydial and gonococcal infections of the oropharynx and rectum in men who have sex with men
    • Schachter J, Moncada J, Liska S, Shayevich C, Klausner JD. Nucleic acid amplification tests in the diagnosis of chlamydial and gonococcal infections of the oropharynx and rectum in men who have sex with men. Sex Transm Dis 2008; 35:637-42.
    • (2008) Sex Transm Dis , vol.35 , pp. 637-642
    • Schachter, J.1    Moncada, J.2    Liska, S.3    Shayevich, C.4    Klausner, J.D.5
  • 14
    • 84856770379 scopus 로고    scopus 로고
    • The emerging threat of untreatable gonococcal infection
    • Bolan GA, Sparling PF, Wasserheit JN. The emerging threat of untreatable gonococcal infection. N Engl J Med 2012; 366:485-7.
    • (2012) N Engl J Med , vol.366 , pp. 485-487
    • Bolan, G.A.1    Sparling, P.F.2    Wasserheit, J.N.3
  • 15
    • 77957231790 scopus 로고    scopus 로고
    • Cephalosporin MIC creep among gonococci time for a pharmacodynamic rethink?
    • Chisholm SA, Mouton JW, Lewis DA, et al. Cephalosporin MIC creep among gonococci: time for a pharmacodynamic rethink?. J Antimicrob Chemother 2010; 65:2141-8.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 2141-2148
    • Chisholm, S.A.1    Mouton, J.W.2    Lewis, D.A.3
  • 16
    • 84857566084 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae with highlevel resistance to azithromycin: Case report of the first isolate identified in the United States
    • Katz AR, Komeya AY, Soge OO, et al. Neisseria gonorrhoeae with highlevel resistance to azithromycin: case report of the first isolate identified in the United States. Clin Infect Dis 2012; 54:841-3.
    • (2012) Clin Infect Dis , vol.54 , pp. 841-843
    • Katz, A.R.1    Komeya, A.Y.2    Soge, O.O.3
  • 18
    • 84857146496 scopus 로고    scopus 로고
    • High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: Novel penA mosaic allele in a successful international clone causes treatment failure
    • Unemo M, Golparian D, Nicholas R, Ohnishi M, Gallay A, Sednaoui P. High-level cefixime- and ceftriaxone-resistant Neisseria gonorrhoeae in France: novel penA mosaic allele in a successful international clone causes treatment failure. Antimicrob Agents Chemother 2011; 56: 1273-80.
    • (2011) Antimicrob Agents Chemother , vol.56 , pp. 1273-1280
    • Unemo, M.1    Golparian, D.2    Nicholas, R.3    Ohnishi, M.4    Gallay, A.5    Sednaoui, P.6
  • 19
    • 84891462477 scopus 로고    scopus 로고
    • Failure of 500 mg of ceftriaxone to eradicate pharyngeal gonorrhoea, Australia
    • Chen MY, Stevens K, Tideman R, et al. Failure of 500 mg of ceftriaxone to eradicate pharyngeal gonorrhoea, Australia. J Antimicrob Chemother 2013; 68:1445-7.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 1445-1447
    • Chen, M.Y.1    Stevens, K.2    Tideman, R.3
  • 20
    • 84886926874 scopus 로고    scopus 로고
    • One confirmed and one suspected case of pharyngeal gonorrhoea treatment failure following 500 mg ceftriaxone in Sydney
    • Read PJ, Limnios EA, McNulty A, Whiley D, Lahra MM. One confirmed and one suspected case of pharyngeal gonorrhoea treatment failure following 500 mg ceftriaxone in Sydney, Australia. Sex Health 2013; 10:460-2.
    • (2013) Australia. Sex Health , vol.10 , pp. 460-462
    • Read, P.J.1    Limnios, E.A.2    McNulty, A.3    Whiley, D.4    Lahra, M.M.5
  • 22
    • 0036792185 scopus 로고    scopus 로고
    • Duration of persistence of gonococcal DNA detected by ligase chain reaction in men and women following recommended therapy for uncomplicated gonorrhea
    • Bachmann LH, Desmond RA, Stephens J, Hughes A, Hook EW 3rd. Duration of persistence of gonococcal DNA detected by ligase chain reaction in men and women following recommended therapy for uncomplicated gonorrhea. J Clin Microbiol 2002; 40:3596-601.
    • (2002) J Clin Microbiol , vol.40 , pp. 3596-3601
    • Bachmann, L.H.1    Desmond, R.A.2    Stephens, J.3    Hughes, A.4    Hook, E.W.5
  • 23
    • 84859753142 scopus 로고    scopus 로고
    • Appropriate time for test-ofcure when diagnosing gonorrhoea with a nucleic acid amplification test
    • Hjelmevoll SO, Olsen ME, Sollid JU, et al. Appropriate time for test-ofcure when diagnosing gonorrhoea with a nucleic acid amplification test. Acta Derm Venereol 2012; 92:316-9.
    • (2012) Acta Derm Venereol , vol.92 , pp. 316-319
    • Hjelmevoll, S.O.1    Olsen, M.E.2    Sollid, J.U.3
  • 24
    • 2142810126 scopus 로고    scopus 로고
    • Laboratory tests used in US public health laboratories for sexually transmitted diseases 2000
    • Dicker LW, Mosure DJ, Steece R, Stone KM. Laboratory tests used in US public health laboratories for sexually transmitted diseases, 2000. Sex Transm Dis 2004; 31:259-64.
    • (2004) Sex Transm Dis , vol.31 , pp. 259-264
    • Dicker, L.W.1    Mosure, D.J.2    Steece, R.3    Stone, K.M.4
  • 25
    • 84895423728 scopus 로고    scopus 로고
    • Molecular diagnostics for gonorrhoea: Implications for antimicrobial resistance and the threat of untreatable gonorrhoea
    • Low N, Unemo M, Skov Jensen J, Breuer J, Stephenson JM. Molecular diagnostics for gonorrhoea: implications for antimicrobial resistance and the threat of untreatable gonorrhoea. PLoS Med 2014; 11:e1001598.
    • (2014) PLoS Med , vol.11 , pp. e1001598
    • Low, N.1    Unemo, M.2    Skov Jensen, J.3    Breuer, J.4    Stephenson, J.M.5
  • 27
    • 84891532699 scopus 로고    scopus 로고
    • Sampling technique is important for optimal isolation of pharyngeal gonorrhoea
    • Mitchell M, Rane V, Fairley CK, et al. Sampling technique is important for optimal isolation of pharyngeal gonorrhoea. Sex Transm Infect 2013; 89:557-60.
    • (2013) Sex Transm Infect , vol.89 , pp. 557-560
    • Mitchell, M.1    Rane, V.2    Fairley, C.K.3
  • 28
    • 84922382788 scopus 로고    scopus 로고
    • Antimicrobial testing and applications in the pathogenic Neisseria. In Merlino J, ed. Antimicrobial susceptibility testing: methods and practices with an Australian perspective. Sydney: Australian Society for Microbiology
    • Tapsall J; Members of the National Neisseria Network of Australia. Antimicrobial testing and applications in the pathogenic Neisseria. In: Merlino J, ed. Antimicrobial susceptibility testing: methods and practices with an Australian perspective. Sydney: Australian Society for Microbiology, 2004; 175-88.
    • (2004) Members of the National Neisseria Network of Australia , pp. 175-188
    • Tapsall, J.1
  • 29
    • 41949091268 scopus 로고    scopus 로고
    • A duplex Neisseria gonorrhoeae real-time polymerase chain reaction assay targeting the gonococcal porA pseudogene and multicopy opa genes
    • Goire N, Nissen MD, LeCornec GM, Sloots TP, Whiley DM. A duplex Neisseria gonorrhoeae real-time polymerase chain reaction assay targeting the gonococcal porA pseudogene and multicopy opa genes. Diagn Microbiol Infect Dis 2008; 61:6-12.
    • (2008) Diagn Microbiol Infect Dis , vol.61 , pp. 6-12
    • Goire, N.1    Nissen, M.D.2    Lecornec, G.M.3    Sloots, T.P.4    Whiley, D.M.5
  • 30
    • 13944275956 scopus 로고    scopus 로고
    • Evaluation of opa-based real-time PCR for detection of Neisseria gonorrhoeae
    • Tabrizi SN, Chen S, Tapsall J, Garland SM. Evaluation of opa-based real-time PCR for detection of Neisseria gonorrhoeae. Sex Transm Dis 2005; 32:199-202.
    • (2005) Sex Transm Dis , vol.32 , pp. 199-202
    • Tabrizi, S.N.1    Chen, S.2    Tapsall, J.3    Garland, S.M.4
  • 31
    • 27144560210 scopus 로고    scopus 로고
    • Comparison of three in-house multiplex PCR assays for the detection of Neisseria gonorrhoeae and Chlamydia trachomatis using real-time and conventional detection methodologies
    • Whiley DM, Sloots TP. Comparison of three in-house multiplex PCR assays for the detection of Neisseria gonorrhoeae and Chlamydia trachomatis using real-time and conventional detection methodologies. Pathology 2005; 37:364-70.
    • (2005) Pathology , vol.37 , pp. 364-370
    • Whiley, D.M.1    Sloots, T.P.2
  • 32
    • 77449149699 scopus 로고    scopus 로고
    • Neisseria gonorrhoeae multi-Antigen sequence typing using non-cultured clinical specimens
    • Whiley DM, Goire N, Ray ES, et al. Neisseria gonorrhoeae multi-Antigen sequence typing using non-cultured clinical specimens. Sex Transm Infect 2010; 86:51-5.
    • (2010) Sex Transm Infect , vol.86 , pp. 51-55
    • Whiley, D.M.1    Goire, N.2    Ray, E.S.3
  • 33
    • 0035146369 scopus 로고    scopus 로고
    • A quantification of human cells using an ERV-3 real time PCR assay
    • Yuan CC, Miley W, Waters D. A quantification of human cells using an ERV-3 real time PCR assay. J Virol Methods 2001; 91: 109-17.
    • (2001) J Virol Methods , vol.91 , pp. 109-117
    • Yuan, C.C.1    Miley, W.2    Waters, D.3
  • 34
    • 84892147661 scopus 로고    scopus 로고
    • Nasal swab samples and real-time polymerase chain reaction assays in community-based, longitudinal studies of respiratory viruses: The importance of sample integrity and quality control
    • Alsaleh AN, Whiley DM, Bialasiewicz S, et al. Nasal swab samples and real-time polymerase chain reaction assays in community-based, longitudinal studies of respiratory viruses: the importance of sample integrity and quality control. BMC Infect Dis 2014; 14:15-7.
    • (2014) BMC Infect Dis , vol.14 , pp. 15-17
    • Alsaleh, A.N.1    Whiley, D.M.2    Bialasiewicz, S.3
  • 35
    • 0037079880 scopus 로고    scopus 로고
    • Increased sensitivity of DNA amplification testing for the detection of pharyngeal gonorrhea in men who have sex with men
    • Page-Shafer K, Graves A, Kent C, Balls JE, Zapitz VM, Klausner JD. Increased sensitivity of DNA amplification testing for the detection of pharyngeal gonorrhea in men who have sex with men. Clin Infect Dis 2002; 34:173-6.
    • (2002) Clin Infect Dis , vol.34 , pp. 173-176
    • Page-Shafer, K.1    Graves, A.2    Kent, C.3    Balls, J.E.4    Zapitz, V.M.5    Klausner, J.D.6
  • 36
    • 82455185147 scopus 로고    scopus 로고
    • Differing Neisseria gonorrhoeae bacterial loads in the pharynx and rectum in men who have sex with men: Implications for gonococcal detection, transmission and control
    • Bissessor M, Tabrizi SN, Fairley CK, et al. Differing Neisseria gonorrhoeae bacterial loads in the pharynx and rectum in men who have sex with men: implications for gonococcal detection, transmission and control. J Clin Microbiol 2011; 49:4304-6.
    • (2011) J Clin Microbiol , vol.49 , pp. 4304-4306
    • Bissessor, M.1    Tabrizi, S.N.2    Fairley, C.K.3
  • 37
    • 29044441713 scopus 로고    scopus 로고
    • Explaining the poor bacteriologic eradication rate of single-dose ceftriaxone in group a streptococcal tonsillopharyngitis: A reverse engineering solution using pharmacodynamic modeling
    • Blumer JL, Reed MD, Kaplan EL, Drusano GL. Explaining the poor bacteriologic eradication rate of single-dose ceftriaxone in group a streptococcal tonsillopharyngitis: a reverse engineering solution using pharmacodynamic modeling. Pediatrics 2005; 116:927-32.
    • (2005) Pediatrics , vol.116 , pp. 927-932
    • Blumer, J.L.1    Reed, M.D.2    Kaplan, E.L.3    Drusano, G.L.4


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