Neisseria gonorrhoeae with high-level resistance to azithromycin: Case report of the first isolate identified in the United States

Clinical Infectious Diseases

Volumn 54, Issue 6, 2012, Pages 841-843

  Katz, Alan R ^a,b   Komeya, Alan Y ^b   Soge, Olusegun O ^c   Kiaha, Mandy I ^b   Maria Veneranda C Lee, ^b   Glenn M Wasserman, ^b   Eloisa V Maningas, ^d   A Christian Whelen, ^a,d   Robert D Kirkcaldy, ^e   Steven J Shapiro, ^e   Gail A Bolan, ^e   King K Holmes, ^c  

^a UNIVERSITY OF HAWAII   (United States)

^b Biomedical Sciences Building ^*  (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d State Laboratories Division   (United States)

^e CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AZITHROMYCIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATE; CASE REPORT; FEMALE; GENE MUTATION; HUMAN; NEISSERIA GONORRHOEAE; NONHUMAN; PRIORITY JOURNAL; SEQUENCE ANALYSIS; UNITED STATES;

ADULT; ANTI-BACTERIAL AGENTS; AZITHROMYCIN; DRUG RESISTANCE, BACTERIAL; FEMALE; GONORRHEA; HAWAII; HUMANS; MALE; MICROBIAL SENSITIVITY TESTS; NEISSERIA GONORRHOEAE; YOUNG ADULT;

EID: 84857566084     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/cir929     Document Type: Article

References (24)

1. Centers for Disease Control and Prevention. Gonococcal isolate surveillance project protocol. Atlanta, GA: US Department of Health and Human Services, Centers for Disease Control and Prevention, 2007. Available at: www.cdc.gov/std/gisp/protocol2006-web-version-rev12-2007.pdf. Accessed 6 December 2011.
2. Hawaii State Department of Health. Medical advisory: first azithromycinresistant gonorrhea isolate. 2011. Available at: http: //hawaii.gov/health/healthy-lifestyles/std-aids/azi.pdf. Accessed 6 December 2011.
3. Centers for Disease Control and Prevention. Dear colleague letter: azithromycin resistance in Hawaii. 2011. Available at: http: //www.cdc.gov/std/gonorrhea/DCL-Azithro-GC-May-24-2011.pdf. Accessed 6 December 2011.
4. Martin IM, Ison CA, Aanensen DM, Fenton KA, Spratt BG. Rapid sequence-based identification of gonococcal transmission clusters in a large metropolitan area. J Infect Dis 2004; 189: 1497-505. (Pubitemid 38552358)
5. Ng LK, Martin I, Liu G, Bryden L. Mutation in 23S rRNA associated with macrolide resistance in Neisseria gonorrhoeae. Antimicrob Agents Chemother 2002; 46: 3020-5.
6. Luna VA, Cousin S Jr, Whittington WL, Roberts MC. Identification of the conjugative mef gene in clinical Acinetobacter junii and Neisseria gonorrhoeae isolates. Antimicrob Agents Chemother 2000; 44: 2503-6. (Pubitemid 30650902)
7. Roberts MC, Chung WO, Roe D, et al. Erythromycin-resistant Neisseria gonorrhoeae and oral commensal Neisseria spp. carry known rRNA methylase genes. Antimicrob Agents Chemother 1999; 43: 1367-72. (Pubitemid 29259327)
8. Cousin SL Jr, Whittington WL, Roberts MC. Acquired macrolide resistance genes and the 1 bp deletion in the mtrR promoter in Neisseria gonorrhoeae. J Antimicrob Chemother 2003; 51: 131-3. (Pubitemid 36163837)
9. Centers for Disease Control and Prevention. Neisseria gonorrhoeae with reduced susceptibility to azithromycin-San Diego County, California, 2009. MMWR Morb Mortal Wkly Rep 2011; 60: 579-81.
10. Galarza PG, Alcalá B, Salcedo C, et al. Emergence of high level azithromycin-resistant Neisseria gonorrhoeae strain isolated in Argentina. Sex Transm Dis 2009; 36: 787-8.
11. Palmer HM, Young H, Winter A, Dave J. Emergence and spread of azithromycin-resistant Neisseria gonorrhoeae in Scotland. J Antimicrob Chemother 2008; 62: 490-4.
12. ChisholmSA, Neal TJ, Alawattegama AB, BirleyHD, Howe RA, Ison CA. Emergence of high-level azithromycin resistance in Neisseria gonorrhoeae in England and Wales. J Antimicrob Chemother 2009; 64: 353-8.
13. Cole MJ, Chisholm SA, Hoffmann S, et al. European surveillance of antimicrobial resistance in Neisseria gonorrhoeae. Sex Transm Infect 2010; 86: 427-32.
14. Starnino S, Stefanelli P. Azithromycin-resistant Neisseria gonorrhoeae strains recently isolated in Italy. J Antimicrob Chemother 2009; 63: 1200-4.
15. Galarza PG, Abad R, Canigia LF, et al. New mutation in 23S rRNA gene associated with high level of azithromycin resistance in Neisseria gonorrhoeae. Antimicrob Agents Chemother 2010; 54: 1652-3.
16. Chisholm SA, Dave J, Ison CA. High-level azithromycin resistance occurs in Neisseria gonorrhoeae as a result of a single point mutation in the 23S rRNA genes. Antimicrob Agents Chemother 2010; 54: 3812-6.
17. Gorwitz RJ, Nakashima AK, Moran JS, Knapp JS. Sentinel surveillance for antimicrobial resistance in Neisseria gonorrhoeae-United States, 1988-1991. The Gonococcal Isolate Surveillance Project Study Group. MMWR CDC Surveill Summ 1993; 42: 29-39.
18. Sarafian SK, Rice RJ, Ohye RG, Higa H, Knapp JS. Diversity of isolates of penicillinase-producing Neisseria gonorrhoeae (PPNG) in Honolulu, Hawaii: 1982-1991. Sex Transm Dis 1994; 21: 332-7. (Pubitemid 24372119)
19. Knapp JS, Ohye R, Neal SW, Parekh MC, Higa H, Rice RJ. Emerging in vitro resistance to quinolones in penicillinase-producing Neisseria gonorrhoeae strains in Hawaii. Antimicrob Agents Chemother 1994; 38: 2200-3. (Pubitemid 24278829)
20. Wang SA, Lee MVC, O'Connor N, et al. Multidrug-resistant Neisseria gonorrhoeae with decreased susceptibility to cefixime-Hawaii, 2001. Clin Infect Dis 2003; 37: 849-52. (Pubitemid 37153668)
21. Centers for Disease Control and Prevention. Consultation meeting on cephalosporin-resistant gonorrhea outbreak response plan. 2009.Available at: http: //www.cdc.gov/std/Gonorrhea/arg/CephOutbreakResponsePlan.pdf. Accessed 6 December 2011.
22. Centers for Disease Control and Prevention. Sexually transmitted diseases treatment guidelines, 2010. MMWR Recomm Rep 2010; 59: 49-55.
23. Centers for Disease Control and Prevention. Cephalosporin susceptibility among Neisseria gonorrhoeae isolates-United States, 2000-2010. MMWR Morb Mortal Wkly Rep 2011; 60: 873-7.
24. Ohnishi M, Saika T, Hoshina S, et al. Ceftriaxone-resistant Neisseria gonorrhoeae, Japan. Emerg Infect Dis 2011; 17: 148-9.