Associations between the 17q21 region and allergic rhinitis in 5 birth cohorts

Journal of Allergy and Clinical Immunology

Volumn 135, Issue 2, 2015, Pages 573-576.e5

  Fuertes, Elaine ^a,b   Söderhäll, Cilla ^c   Acevedo, Nathalie ^c   Becker, Allan ^d   Brauer, Michael ^a   Chan Yeung, Moira ^a   Dijk, F Nicole ^e   Heinrich, Joachim ^b   De Jongste, Johan ^f   Koppelman, Gerard H ^e   Postma, Dirkje S ^g   Kere, Juha ^c,h   Kozyrskyj, Anita L ⁱ   Pershagen, Göran ^c   Sandford, Andrew ^a   Standl, Marie ^b   Tiesler, Carla M T ^b,j   Waldenberger, Melanie ^b   Westman, Marit ^k   Carlsten, Christopher ^a   Melén, Erik ^c,l   more..

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UNIVERSITY OF MANITOBA   (Canada)

^e UNIVERSITY OF GRONINGEN   (Netherlands)

^f SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^g UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^h UNIVERSITY OF HELSINKI   (Finland)

ⁱ UNIVERSITY OF ALBERTA   (Canada)

^j LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^k KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^l SACHS CHILDREN S HOSPITAL   (Sweden)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALLERGIC RHINITIS; ASTHMA; CHROMOSOME 17Q; COHORT ANALYSIS; GENE EXPRESSION; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HERITABILITY; HUMAN; LETTER; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; CHROMOSOME 17; GENETIC PREDISPOSITION; GENETICS;

ASTHMA; CHROMOSOMES, HUMAN, PAIR 17; COHORT STUDIES; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; RHINITIS, ALLERGIC;

EID: 84922381164     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.08.016     Document Type: Article

References (20)

1. M.F. Moffatt, M. Kabesch, L. Liang, A.L. Dixon, D. Strachan, and S. Heath Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma Nature 448 2007 470 473
2. M.A.R. Ferreira, M.C. Matheson, C.S. Tang, R. Granell, W. Ang, and J. Hui Genome-wide association analysis identifies 11 risk variants associated with the asthma with hay fever phenotype J Allergy Clin Immunol 133 2014 1564 1571
3. K. Tomita, M. Sakashita, T. Hirota, S. Tanaka, K. Masuyama, and T. Yamada Variants in the 17q21 asthma susceptibility locus are associated with allergic rhinitis in the Japanese population Allergy 68 2013 92 100
4. A.K. Andiappan, D.Y. Wang, R. Anantharaman, P.N. Parate, B.K. Suri, and H.Q. Low Genome-wide association study for atopy and allergic rhinitis in a Singapore Chinese population PLoS One 6 2011 e19719
5. A. Ramasamy, I. Curjuric, L.J. Coin, A. Kumar, W.L. McArdle, and M. Imboden A genome-wide meta-analysis of genetic variants associated with allergic rhinitis and grass sensitization and their interaction with birth order J Allergy Clin Immunol 128 2011 996 1005
6. D.A. Hinds, G. McMahon, A.K. Kiefer, C.B. Do, N. Eriksson, and D.M. Evans A genome-wide association meta-analysis of self-reported allergy identifies shared and allergy-specific susceptibility loci Nat Genet 45 2013 907 911
7. D.J. Verlaan, S. Berlivet, G.M. Hunninghake, A.-M. Madore, M. Larivière, and S. Moussette Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease Am J Hum Genet 85 2009 377 393
8. K. Hao, Y. Bossé, D.C. Nickle, P.D. Paré, D.S. Postma, and M. Laviolette Lung eQTLs to help reveal the molecular underpinnings of asthma PLoS Genet 8 2012 e1003029
9. S.G. Ha, X.N. Ge, N.S. Bahaie, B.N. Kang, A. Rao, and S.P. Rao ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CD48 Nat Commun 4 2013 2479
10. O. Delaneau, J. Marchini, and J.-F. Zagury A linear complexity phasing method for thousands of genomes Nat Methods 9 2012 179 181
11. O. Delaneau, J.-F. Zagury, and J. Marchini Improved whole-chromosome phasing for disease and population genetic studies Nat Methods 10 2013 5 6
12. B.N. Howie, P. Donnelly, and J. Marchini A flexible and accurate genotype imputation method for the next generation of genome-wide association studies PLoS Genet 5 2009 e1000529
13. M. Moffatt, I. Gut, F. Demenais, D. Strachan, E. Bouzigon, and S. Heath A large-scale, consortium-based genomewide association study of asthma N Engl J Med 363 2010 1211 1221
14. Y. Li, C.J. Willer, J. Ding, P. Scheet, and G.R. Abecasis MaCH: using sequence and genotype data to estimate haplotypes and unobserved genotypes Genet Epidemiol 34 2010 816 834
15. M. Wickman, G. Pershagen, and S.L. Nordvall The BAMSE project: presentation of a prospective longitudinal birth cohort study Pediatr Allergy Immunol 13 2002 11 13
16. M. Chan-Yeung, J. Manfreda, H. Dimich-Ward, A. Ferguson, W. Watson, and A. Becker A randomized controlled study on the effectiveness of a multifaceted intervention program in the primary prevention of asthma in high-risk infants Arch Pediatr Adolesc Med 154 2000 657 663
17. B. Filipiak, A. Zutavern, S. Koletzko, A. von Berg, I. Brockow, and A. Grübl Solid food introduction in relation to eczema: results from a four-year prospective birth cohort study J Pediatr 151 2007 352 358
18. J. Heinrich, G. Bolte, B. Hölscher, J. Douwes, I. Lehmann, and B. Fahlbusch Allergens and endotoxin on mothers' mattresses and total immunoglobulin E in cord blood of neonates Eur Respir J 20 2002 617 623
19. B. Brunekreef, J. Smit, J. de Jongste, H. Neijens, J. Gerritsen, and D. Postma The prevention and incidence of asthma and mite allergy (PIAMA) birth cohort study: design and first results Pediatr Allergy Immunol 13 2002 55 60
20. A.L. Kozyrskyj, K.T. HayGlass, A. Sandford, P.D. Pare, M. Chan-Yeung, and A.B. Becker A novel study design to investigate the early-life origins of asthma in children (SAGE study) Allergy 64 2009 1185 1193