Worms as therapeutic agents for allergy and asthma: Understanding why benefits in animal studies have not translated into clinical success

Journal of Allergy and Clinical Immunology

Volumn 135, Issue 2, 2015, Pages 343-353

  Evans, Holly ^a   Mitre, Edward ^a  

^a UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Allergy; animal models; asthma; atopy; clinical trials; helminths; hygiene hypothesis; therapeutics

Indexed keywords

ANTIHISTAMINIC AGENT; CORTICOSTEROID; PARASITE ANTIGEN;

ALLERGIC DISEASE; ALLERGIC RHINITIS; ANTIBODY TITER; ARTICLE; ASTHMA; COMPARATIVE STUDY; DISEASE DURATION; DOUBLE BLIND PROCEDURE; GENETICS; HELIGMOSOMOIDES POLYGYRUS; HELMINTHIASIS; HUMAN; IMMUNOMODULATION; IMMUNOTHERAPY; LITOMOSOIDES SIGMODONTIS; NECATOR AMERICANUS; NONHUMAN; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); SCHISTOSOMA JAPONICUM; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; SENSITIZATION; STRONGYLOIDES STERCORALIS; THERAPY EFFECT; THERAPY WITH HELMINTHS; TRICHINELLA SPIRALIS; TRICHURIS SUIS; WORM; ANIMAL; CLINICAL TRIAL (TOPIC); HELMINTH; HYPERSENSITIVITY; IMMUNOLOGY;

ANIMALS; ANTIGENS, HELMINTH; ASTHMA; CLINICAL TRIALS AS TOPIC; HELMINTHIASIS; HELMINTHS; HUMANS; HYPERSENSITIVITY; IMMUNOTHERAPY;

EID: 84922353785     PISSN: 00916749     EISSN: 10976825     Source Type: Journal    
DOI: 10.1016/j.jaci.2014.07.007     Document Type: Review

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