Impact of the neutrophil response to granulocyte colony-stimulating factor on the risk of hemorrhage when used in combination with tissue plasminogen activator during the acute phase of experimental stroke

Journal of Neuroinflammation

Volumn 11, Issue 1, 2014, Pages

  Gautier, Sophie ^a   Ouk, Thavarak ^a   Tagzirt, Madjid ^b   Lefebvre, Catherine ^a,c   Laprais, Maud ^a   Pétrault, Olivier ^a   Dupont, Annabelle ^b   Leys, Didier ^c   Bordet, Régis ^a  

^a UNIV LILLE   (France)

^b LILLE UNIVERSITY HOSPITAL   (France)

^c EA 2691 Service de Neurologie et Pathologies Vasculaires   (France)

Author keywords

G CSF; Hemorrhage; Neutrophil; Stroke; TPA; Vascular endothelium

Indexed keywords

ALTEPLASE; GELATINASE B; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; FIBRINOLYTIC AGENT; GRANULOCYTE COLONY STIMULATING FACTOR; PEROXIDASE; TISSUE PLASMINOGEN ACTIVATOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD CLOT LYSIS; BLOOD VESSEL REACTIVITY; BRAIN HEMORRHAGE; BRAIN INFARCTION; BRAIN INFARCTION SIZE; BRAIN ISCHEMIA; CONTROLLED STUDY; DEGRANULATION; DRUG EFFICACY; ENDOTHELIAL DYSFUNCTION; ENZYME RELEASE; EX VIVO STUDY; IMMUNOCHEMISTRY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; RAT; RISK ASSESSMENT; SPONTANEOUSLY HYPERTENSIVE RAT; ZYMOGRAPHY; ANIMAL; BLEEDING; CHEMICALLY INDUCED; DISEASE MODEL; DRUG ADMINISTRATION; DRUG EFFECTS; ENDOTHELIUM; INFARCTION, MIDDLE CEREBRAL ARTERY; METABOLISM; NEUTROPHIL; NONPARAMETRIC TEST; REPERFUSION INJURY; TIME;

ANIMALS; BRAIN INFARCTION; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION SCHEDULE; ENDOTHELIUM; FIBRINOLYTIC AGENTS; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMORRHAGE; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; MATRIX METALLOPROTEINASE 9; NEUTROPHIL INFILTRATION; NEUTROPHILS; PEROXIDASE; RATS; RATS, INBRED SHR; REPERFUSION INJURY; STATISTICS, NONPARAMETRIC; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84921649912     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-11-96     Document Type: Article

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