메뉴 건너뛰기




Volumn 81, Issue 2, 2015, Pages 112-118

Results of the surveillance of tedizolid activity and resistance program: In vitro susceptibility of gram-positive pathogens collected in 2011 and 2012 from the United States and Europe

Author keywords

Cfr; Linezolid; Oxazolidinone; Surveillance; Tedizolid

Indexed keywords

LINEZOLID; RIBOSOMAL PROTEIN L3; RIBOSOMAL PROTEIN L4; RIBOSOME PROTEIN; RNA 23S; TEDIZOLID; UNCLASSIFIED DRUG; ACETAMIDE DERIVATIVE; ANTIINFECTIVE AGENT; ORGANOPHOSPHATE; OXAZOLE DERIVATIVE; OXAZOLIDINONE DERIVATIVE;

EID: 84922309807     PISSN: 07328893     EISSN: 18790070     Source Type: Journal    
DOI: 10.1016/j.diagmicrobio.2014.08.011     Document Type: Article
Times cited : (67)

References (38)
  • 1
    • 42049096982 scopus 로고    scopus 로고
    • Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances
    • Besier S., Ludwig A., Zander J., Brade V., Wichelhaus T.A. Linezolid resistance in Staphylococcus aureus: gene dosage effect, stability, fitness costs, and cross-resistances. Antimicrob Agents Chemother 2008, 52:1570-1572.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1570-1572
    • Besier, S.1    Ludwig, A.2    Zander, J.3    Brade, V.4    Wichelhaus, T.A.5
  • 3
    • 77951234516 scopus 로고    scopus 로고
    • Comparative in vitro antimicrobial activities of torezolid (TR-700), the active moiety of a new oxazolidinone, torezolid phosphate (TR-701), determination of tentative disk diffusion interpretive criteria, and quality control ranges
    • Brown S.D., Traczewski M.M. Comparative in vitro antimicrobial activities of torezolid (TR-700), the active moiety of a new oxazolidinone, torezolid phosphate (TR-701), determination of tentative disk diffusion interpretive criteria, and quality control ranges. Antimicrob Agents Chemother 2010, 54:2063-2069.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 2063-2069
    • Brown, S.D.1    Traczewski, M.M.2
  • 6
    • 84870790006 scopus 로고    scopus 로고
    • ZAAPS Program results for 2010: an activity and spectrum analysis of linezolid using clinical isolates from 75 medical centers in 24 countries
    • Flamm R.K., Farrell D.J., Mendes R.E., Ross J.E., Sader H.S., Jones R.N. ZAAPS Program results for 2010: an activity and spectrum analysis of linezolid using clinical isolates from 75 medical centers in 24 countries. J Chemother 2012, 24:328-337.
    • (2012) J Chemother , vol.24 , pp. 328-337
    • Flamm, R.K.1    Farrell, D.J.2    Mendes, R.E.3    Ross, J.E.4    Sader, H.S.5    Jones, R.N.6
  • 7
    • 84872867684 scopus 로고    scopus 로고
    • Linezolid surveillance results for the United States: LEADER surveillance program 2011
    • Flamm R.K., Mendes R.E., Ross J.E., Sader H.S., Jones R.N. Linezolid surveillance results for the United States: LEADER surveillance program 2011. Antimicrob Agents Chemother 2013, 57:1077-1081.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 1077-1081
    • Flamm, R.K.1    Mendes, R.E.2    Ross, J.E.3    Sader, H.S.4    Jones, R.N.5
  • 8
    • 79952280648 scopus 로고    scopus 로고
    • Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent
    • Im W.B., Choi S.H., Park J.Y., Choi S.H., Finn J., Yoon S.H. Discovery of torezolid as a novel 5-hydroxymethyl-oxazolidinone antibacterial agent. Eur J Med Chem 2011, 46(4):1027-1039.
    • (2011) Eur J Med Chem , vol.46 , Issue.4 , pp. 1027-1039
    • Im, W.B.1    Choi, S.H.2    Park, J.Y.3    Choi, S.H.4    Finn, J.5    Yoon, S.H.6
  • 9
    • 31544471208 scopus 로고    scopus 로고
    • Oxazolidinone susceptibility patterns in 2004: report from the Zyvox® Annual Appraisal of Potency and Spectrum (ZAAPS) program assessing isolates from 16 nations
    • Jones R.N., Ross J.E., Fritsche T.R., Sader H.S. Oxazolidinone susceptibility patterns in 2004: report from the Zyvox® Annual Appraisal of Potency and Spectrum (ZAAPS) program assessing isolates from 16 nations. J Antimicrob Chemother 2006, 57:279-287.
    • (2006) J Antimicrob Chemother , vol.57 , pp. 279-287
    • Jones, R.N.1    Ross, J.E.2    Fritsche, T.R.3    Sader, H.S.4
  • 10
    • 77950467121 scopus 로고    scopus 로고
    • Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria
    • Kaminska K.H., Purta E., Hansen L.H., Bujnicki J.M., Vester B., Long K.S. Insights into the structure, function and evolution of the radical-SAM 23S rRNA methyltransferase Cfr that confers antibiotic resistance in bacteria. Nucleic Acids Res 2010, 38:1652-1663.
    • (2010) Nucleic Acids Res , vol.38 , pp. 1652-1663
    • Kaminska, K.H.1    Purta, E.2    Hansen, L.H.3    Bujnicki, J.M.4    Vester, B.5    Long, K.S.6
  • 11
    • 77955818964 scopus 로고    scopus 로고
    • Molecular and epidemiologic characteristics of linezolid-resistant coagulase-negative staphylococci at a tertiary care hospital
    • Kosowska-Shick K., Julian K.G., McGhee P.L., Appelbaum P.C., Whitener C.J. Molecular and epidemiologic characteristics of linezolid-resistant coagulase-negative staphylococci at a tertiary care hospital. Diagn Microbiol Infect Dis 2010, 68:34-39.
    • (2010) Diagn Microbiol Infect Dis , vol.68 , pp. 34-39
    • Kosowska-Shick, K.1    Julian, K.G.2    McGhee, P.L.3    Appelbaum, P.C.4    Whitener, C.J.5
  • 12
    • 84896447005 scopus 로고    scopus 로고
    • Investigation of a multiresistance gene cfr that fails to mediate resistance to phenicols and oxazolidinones in Enterococcus faecalis
    • Liu Y., Wang Y., Schwarz S., Wang S., Chen L., Wu C., et al. Investigation of a multiresistance gene cfr that fails to mediate resistance to phenicols and oxazolidinones in Enterococcus faecalis. J Antimicrob Chemother 2014, 69:892-898.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 892-898
    • Liu, Y.1    Wang, Y.2    Schwarz, S.3    Wang, S.4    Chen, L.5    Wu, C.6
  • 13
    • 71249138911 scopus 로고    scopus 로고
    • Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700)
    • Locke J.B., Hilgers M., Shaw K.J. Novel ribosomal mutations in Staphylococcus aureus strains identified through selection with the oxazolidinones linezolid and torezolid (TR-700). Antimicrob Agents Chemother 2009, 53:5265-5274.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 5265-5274
    • Locke, J.B.1    Hilgers, M.2    Shaw, K.J.3
  • 14
    • 71249101537 scopus 로고    scopus 로고
    • Mutations in ribosomal protein L3 are associated with oxazolidinone resistance in staphylococci of clinical origin
    • Locke J.B., Hilgers M., Shaw K.J. Mutations in ribosomal protein L3 are associated with oxazolidinone resistance in staphylococci of clinical origin. Antimicrob Agents Chemother 2009, 53:5275-5278.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 5275-5278
    • Locke, J.B.1    Hilgers, M.2    Shaw, K.J.3
  • 15
    • 78649668302 scopus 로고    scopus 로고
    • Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations
    • Locke J.B., Finn J., Hilgers M., Morales G., Rahawi S., G C K., et al. Structure-activity relationships of diverse oxazolidinones for linezolid-resistant Staphylococcus aureus strains possessing the cfr methyltransferase gene or ribosomal mutations. Antimicrob Agents Chemother 2010, 54:5337-5343.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 5337-5343
    • Locke, J.B.1    Finn, J.2    Hilgers, M.3    Morales, G.4    Rahawi, S.G.C.K.5
  • 16
    • 84922282208 scopus 로고    scopus 로고
    • Genetic environment and stability of cfr in methicillin-resistant Staphylococcus aureus CM05
    • Locke J.B., Rahawi S., Lamarre J., Mankin A.S., Shaw K.J. Genetic environment and stability of cfr in methicillin-resistant Staphylococcus aureus CM05. Antimicrob Agents Chemother 2012, 53:5265-5274.
    • (2012) Antimicrob Agents Chemother , vol.53 , pp. 5265-5274
    • Locke, J.B.1    Rahawi, S.2    Lamarre, J.3    Mankin, A.S.4    Shaw, K.J.5
  • 17
    • 84856068450 scopus 로고    scopus 로고
    • Resistance to linezolid caused by modifications at its binding site on the ribosome
    • Long K.S., Vester B. Resistance to linezolid caused by modifications at its binding site on the ribosome. Antimicrob Agents Chemother 2012, 56:603-612.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 603-612
    • Long, K.S.1    Vester, B.2
  • 18
    • 33745599646 scopus 로고    scopus 로고
    • The Cfr rRNA methyltransferase confers resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A antibiotics
    • Long K.S., Poehlsgaard J., Kehrenberg C., Schwarz S., Vester B. The Cfr rRNA methyltransferase confers resistance to phenicols, lincosamides, oxazolidinones, pleuromutilins, and streptogramin A antibiotics. Antimicrob Agents Chemother 2006, 50:2500-2505.
    • (2006) Antimicrob Agents Chemother , vol.50 , pp. 2500-2505
    • Long, K.S.1    Poehlsgaard, J.2    Kehrenberg, C.3    Schwarz, S.4    Vester, B.5
  • 20
    • 3242683097 scopus 로고    scopus 로고
    • Linezolid resistance in sequential Staphylococcus aureus isolates associated with a T2500A mutation in the 23S rRNA gene and loss of a single copy of rRNA
    • Meka V.G., Pillai S.K., Sakoulas G., Wennersten C., Venkataraman L., DeGirolami P.C., et al. Linezolid resistance in sequential Staphylococcus aureus isolates associated with a T2500A mutation in the 23S rRNA gene and loss of a single copy of rRNA. J Infect Dis 2004, 190:311-317.
    • (2004) J Infect Dis , vol.190 , pp. 311-317
    • Meka, V.G.1    Pillai, S.K.2    Sakoulas, G.3    Wennersten, C.4    Venkataraman, L.5    DeGirolami, P.C.6
  • 21
    • 44449125584 scopus 로고    scopus 로고
    • First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States
    • Mendes R.E., Deshpande L.M., Castanheira M., DiPersio J., Saubolle M.A., Jones R.N. First report of cfr-mediated resistance to linezolid in human staphylococcal clinical isolates recovered in the United States. Antimicrob Agents Chemother 2008, 52:2244-2246.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 2244-2246
    • Mendes, R.E.1    Deshpande, L.M.2    Castanheira, M.3    DiPersio, J.4    Saubolle, M.A.5    Jones, R.N.6
  • 22
    • 77957873178 scopus 로고    scopus 로고
    • Assessment of linezolid resistance mechanisms among Staphylococcus epidermidis causing bacteraemia in Rome, Italy
    • Mendes R.E., Deshpande L.M., Farrell D.J., Spanu T., Fadda G., Jones R.N. Assessment of linezolid resistance mechanisms among Staphylococcus epidermidis causing bacteraemia in Rome, Italy. J Antimicrob Chemother 2010, 65:2329-2335.
    • (2010) J Antimicrob Chemother , vol.65 , pp. 2329-2335
    • Mendes, R.E.1    Deshpande, L.M.2    Farrell, D.J.3    Spanu, T.4    Fadda, G.5    Jones, R.N.6
  • 23
    • 84893458897 scopus 로고    scopus 로고
    • Summary of linezolid activity and resistance mechanisms detected during the 2012 LEADER surveillance program for the United States
    • Mendes R.E., Flamm R.K., Hogan P.A., Ross J.E., Jones R.N. Summary of linezolid activity and resistance mechanisms detected during the 2012 LEADER surveillance program for the United States. Antimicrob Agents Chemother 2014, 58:1243-1247.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 1243-1247
    • Mendes, R.E.1    Flamm, R.K.2    Hogan, P.A.3    Ross, J.E.4    Jones, R.N.5
  • 24
    • 84902541725 scopus 로고    scopus 로고
    • Zyvox® Annual Appraisal of Potency and Spectrum (ZAAPS) Program: report of linezolid activity over 9 years (2004-12)
    • Mendes R.E., Hogan P.A., Streit J.M., Jones R.N., Flamm R.K. Zyvox® Annual Appraisal of Potency and Spectrum (ZAAPS) Program: report of linezolid activity over 9 years (2004-12). J Antimicrob Chemother 2014, 69(6):1582-1588.
    • (2014) J Antimicrob Chemother , vol.69 , Issue.6 , pp. 1582-1588
    • Mendes, R.E.1    Hogan, P.A.2    Streit, J.M.3    Jones, R.N.4    Flamm, R.K.5
  • 25
    • 84904718296 scopus 로고    scopus 로고
    • Once-daily tedizolid for 6 days versus twice-daily linezolid for 10 days in acute bacterial skin and skin structure infections: results from a randomised controlled trial using an intravenous-to-oral switch strategy (ESTABLISH-2 study)
    • Moran G.J., Fang E., Corey G.R., Das A.F., De Anda C., Prokocimer P. Once-daily tedizolid for 6 days versus twice-daily linezolid for 10 days in acute bacterial skin and skin structure infections: results from a randomised controlled trial using an intravenous-to-oral switch strategy (ESTABLISH-2 study). Lancet Infect Dis 2014, 14(8):696-705.
    • (2014) Lancet Infect Dis , vol.14 , Issue.8 , pp. 696-705
    • Moran, G.J.1    Fang, E.2    Corey, G.R.3    Das, A.F.4    De Anda, C.5    Prokocimer, P.6
  • 27
    • 0036890601 scopus 로고    scopus 로고
    • Linezolid resistance in Staphylococcus aureus: characterization and stability of resistant phenotype
    • Pillai S.K., Sakoulas G., Wennersten C., Eliopoulos G.M., Moellering R.C., Ferraro M.J., et al. Linezolid resistance in Staphylococcus aureus: characterization and stability of resistant phenotype. J Infect Dis 2002, 186:1603-1607.
    • (2002) J Infect Dis , vol.186 , pp. 1603-1607
    • Pillai, S.K.1    Sakoulas, G.2    Wennersten, C.3    Eliopoulos, G.M.4    Moellering, R.C.5    Ferraro, M.J.6
  • 28
    • 78751689284 scopus 로고    scopus 로고
    • Phase 2, randomized, double-blind, dose-ranging study evaluating the safety, tolerability, population pharmacokinetics, and efficacy of oral torezolid phosphate in patients with complicated skin and skin structure infections
    • Prokocimer P., Bien P., Surber J., Mehra P., DeAnda C., Bulitta J.B., et al. Phase 2, randomized, double-blind, dose-ranging study evaluating the safety, tolerability, population pharmacokinetics, and efficacy of oral torezolid phosphate in patients with complicated skin and skin structure infections. Antimicrob Agents Chemother 2011, 55:583-592.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 583-592
    • Prokocimer, P.1    Bien, P.2    Surber, J.3    Mehra, P.4    DeAnda, C.5    Bulitta, J.B.6
  • 29
    • 84865432225 scopus 로고    scopus 로고
    • In vitro activity and microbiological efficacy of tedizolid (TR-700) against Gram-positive clinical isolates from a phase 2 study of oral tedizolid phosphate (TR-701) in patients with complicated skin and skin structure infections
    • Prokocimer P., Bien P., DeAnda C., Pillar C.M., Bartizal K. In vitro activity and microbiological efficacy of tedizolid (TR-700) against Gram-positive clinical isolates from a phase 2 study of oral tedizolid phosphate (TR-701) in patients with complicated skin and skin structure infections. Antimicrob Agents Chemother 2012, 56:4608-4613.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4608-4613
    • Prokocimer, P.1    Bien, P.2    DeAnda, C.3    Pillar, C.M.4    Bartizal, K.5
  • 30
    • 84873642637 scopus 로고    scopus 로고
    • Tedizolid phosphate vs linezolid for treatment of acute bacterial skin and skin structure infections: the ESTABLISH-1 randomized trial
    • Prokocimer P., De Anda C., Fang E., Mehra P., Das A. Tedizolid phosphate vs linezolid for treatment of acute bacterial skin and skin structure infections: the ESTABLISH-1 randomized trial. JAMA 2013, 309:559-569.
    • (2013) JAMA , vol.309 , pp. 559-569
    • Prokocimer, P.1    De Anda, C.2    Fang, E.3    Mehra, P.4    Das, A.5
  • 31
    • 0034962929 scopus 로고    scopus 로고
    • Resistance to linezolid: character of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci
    • Prystowsky J., Siddiqui F., Chosay J., Shinabarger D.L., Millichap J., Peterson L.R., et al. Resistance to linezolid: character of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci. Antimicrob Agents Chemother 2001, 45:2154-2156.
    • (2001) Antimicrob Agents Chemother , vol.45 , pp. 2154-2156
    • Prystowsky, J.1    Siddiqui, F.2    Chosay, J.3    Shinabarger, D.L.4    Millichap, J.5    Peterson, L.R.6
  • 32
    • 67749127546 scopus 로고    scopus 로고
    • In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agent
    • Schaadt R., Sweeney D., Shinabarger D., Zurenko G. In vitro activity of TR-700, the active ingredient of the antibacterial prodrug TR-701, a novel oxazolidinone antibacterial agent. Antimicrob Agents Chemother 2009, 53:3236-3239.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 3236-3239
    • Schaadt, R.1    Sweeney, D.2    Shinabarger, D.3    Zurenko, G.4
  • 33
    • 57049089598 scopus 로고    scopus 로고
    • In vitro activity of TR-700, the antibacterial moiety of the prodrug TR-701, against linezolid-resistant strains
    • Shaw K.J., Poppe S., Schaadt R., Brown-Driver V., Finn J., Pillar C.M., et al. In vitro activity of TR-700, the antibacterial moiety of the prodrug TR-701, against linezolid-resistant strains. Antimicrob Agents Chemother 2008, 52:4442-4447.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 4442-4447
    • Shaw, K.J.1    Poppe, S.2    Schaadt, R.3    Brown-Driver, V.4    Finn, J.5    Pillar, C.M.6
  • 34
    • 42949115806 scopus 로고    scopus 로고
    • Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors
    • Smith L.K., Mankin A.S. Transcriptional and translational control of the mlr operon, which confers resistance to seven classes of protein synthesis inhibitors. Antimicrob Agents Chemother 2008, 52:1703-1712.
    • (2008) Antimicrob Agents Chemother , vol.52 , pp. 1703-1712
    • Smith, L.K.1    Mankin, A.S.2
  • 35
    • 34250028674 scopus 로고    scopus 로고
    • Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid
    • Toh S.M., Xiong L., Arias C.A., Villegas M.V., Lolans K., Quinn J., et al. Acquisition of a natural resistance gene renders a clinical strain of methicillin-resistant Staphylococcus aureus resistant to the synthetic antibiotic linezolid. Mol Microbiol 2007, 64:1506-1514.
    • (2007) Mol Microbiol , vol.64 , pp. 1506-1514
    • Toh, S.M.1    Xiong, L.2    Arias, C.A.3    Villegas, M.V.4    Lolans, K.5    Quinn, J.6
  • 37
    • 23044470241 scopus 로고    scopus 로고
    • Novel mechanism of resistance to oxazolidinones, macrolides, and chloramphenicol in ribosomal protein L4 of the pneumococcus
    • Wolter N., Smith A.M., Farrell D.J., Schaffner W., Moore M., Whitney C.G., et al. Novel mechanism of resistance to oxazolidinones, macrolides, and chloramphenicol in ribosomal protein L4 of the pneumococcus. Antimicrob Agents Chemother 2005, 49:3554-3557.
    • (2005) Antimicrob Agents Chemother , vol.49 , pp. 3554-3557
    • Wolter, N.1    Smith, A.M.2    Farrell, D.J.3    Schaffner, W.4    Moore, M.5    Whitney, C.G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.