Decreased HIV type 1 transcription in CCR5-Δ32 heterozygotes during suppressive antiretroviral therapy

Journal of Infectious Diseases

Volumn 210, Issue 11, 2014, Pages 1838-1843

  Wang, Charlene ^a,b   Abdel Mohsen, Mohamed ^b   Strain, Matthew C ^d,e   Lada, Steven M ^d,e   Yukl, Steven ^b,c   Cockerham, Leslie R ^b   Pilcher, Christopher D ^b   Hecht, Frederick M ^b   Sinclair, Elizabeth ^b   Liegler, Teri ^b   Richman, Douglas D ^d,e   Deeks, Steven G ^b   Pillai, Satish K ^b  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c SAN FRANCISCO VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

CCR5; Coreceptor; Eradication; HIV; HIV replication; HIV transcription; Latency; NF B; Reservoir; 32

Indexed keywords

ANTIRETROVIRUS AGENT; CHEMOKINE RECEPTOR CCR5; CIRCULAR DNA; VIRUS RNA;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CELL SURFACE; CONTROLLED STUDY; DRUG EFFECT; GENETIC CODE; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNE RESPONSE; MAJOR CLINICAL STUDY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; VIRUS CARRIER; VIRUS LOAD; VIRUS TRANSCRIPTION; VIRUS VIRULENCE; WILD TYPE; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; COHORT ANALYSIS; GENE EXPRESSION REGULATION; GENETICS; GENOTYPE; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV INFECTIONS; IMMUNOLOGY; METABOLISM; MUTATION; VIROLOGY;

ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; COHORT STUDIES; GENE EXPRESSION REGULATION, VIRAL; GENOTYPE; HETEROZYGOTE; HIV INFECTIONS; HIV-1; HUMANS; MUTATION; PHENOTYPE; RECEPTORS, CCR5; RNA, VIRAL; VIRAL LOAD;

EID: 84922277880     PISSN: 00221899     EISSN: 15376613     Source Type: Journal    
DOI: 10.1093/infdis/jiu338     Document Type: Article

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