Aryl hydrocarbon receptor (AhR) agonists increase airway epithelial matrix metalloproteinase activity

Journal of Molecular Medicine

Volumn 92, Issue 6, 2014, Pages 615-628

  Tsai, Ming Ju ^a,b   Hsu, Ya Lin ^a   Wang, Tsu Nai ^c   Wu, Ling Yu ^a   Lien, Chi Tun ^a,b   Hung, Chih Hsing ^c,d,e   Kuo, Po Lin ^a,b,c   Huang, Ming Shyan ^a,b,e  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^c KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^d KAOHSIUNG MUNICIPAL HSIAO KANG HOSPITAL   (Taiwan)

^e KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Airway remodeling; Aryl hydrocarbon receptor; Asthma; Chronic obstructive pulmonary disease; Matrix metalloproteinase

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR AGONIST; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; GELATINASE A; INTERSTITIAL COLLAGENASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN C FOS; PROTEIN C JUN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; XENOBIOTIC AGENT; AROMATIC HYDROCARBON RECEPTOR; GELATINASE B; SMALL INTERFERING RNA;

ARTICLE; BRONCHUS MUCOSA; CALCIUM CELL LEVEL; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; RESPIRATORY EPITHELIUM; SIGNAL TRANSDUCTION; ADULT; AGONISTS; ASTHMA; CELL LINE; GENETICS; MALE; METABOLISM; MIDDLE AGED; PHOSPHORYLATION; PHYSIOLOGY;

ADULT; ASTHMA; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL LINE; HUMANS; MALE; MATRIX METALLOPROTEINASE 1; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FOS; RECEPTORS, ARYL HYDROCARBON; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1;

EID: 84922271666     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-014-1121-x     Document Type: Article

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