메뉴 건너뛰기




Volumn 27, Issue 2, 2015, Pages 233-239

Fetal consequences of maternal antiretroviral nucleoside reverse transcriptase inhibitor use in human and nonhuman primate pregnancy

Author keywords

aneuploidy; electron microscopy; genotoxicity; mitochondrial DNA; zidovudine

Indexed keywords

ANTIRETROVIRUS AGENT; BIOLOGICAL MARKER; MITOCHONDRIAL DNA; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE;

EID: 84922268983     PISSN: 10408703     EISSN: 1531698X     Source Type: Journal    
DOI: 10.1097/MOP.0000000000000193     Document Type: Review
Times cited : (32)

References (31)
  • 1
    • 84904566669 scopus 로고    scopus 로고
    • Realization of an AIDS-free generation: Ensuring sustainable treatment for children
    • Heidari S, Mofenson LM, Bekker LG. Realization of an aids-free generation: ensuring sustainable treatment for children. JAMA 2014; 312: 339-340.
    • (2014) JAMA , vol.312 , pp. 339-340
    • Heidari, S.1    Mofenson, L.M.2    Bekker, L.G.3
  • 2
    • 84889663532 scopus 로고    scopus 로고
    • Eliminating mother to child transmission of HIV-1 and keeping mothers alive: Recent progress
    • Govender T, Coovadia H. Eliminating mother to child transmission of HIV-1 and keeping mothers alive: recent progress. J Infect 2014; 68 (Suppl 1): S57-62
    • (2014) J Infect , vol.68 , pp. S57-S62
    • Govender, T.1    Coovadia, H.2
  • 3
    • 78649829531 scopus 로고    scopus 로고
    • Impact of mitochondrial toxicity of HIV-1 antiretroviral drugs on lipodystrophy and metabolic dysregulation
    • Feeney ER, Mallon PW. Impact of mitochondrial toxicity of HIV-1 antiretroviral drugs on lipodystrophy and metabolic dysregulation. Curr Pharm Des 2010; 16: 3339-3351
    • (2010) Curr Pharm des , vol.16 , pp. 3339-3351
    • Feeney, E.R.1    Mallon, P.W.2
  • 4
    • 0030715604 scopus 로고    scopus 로고
    • Transplacental effects of 3-azido- 2 3-dideoxythymidine (AZT): Tumorigenicity in mice and genotoxicity in mice and monkeys
    • Olivero OA, Anderson LM, Diwan BA,. et al. Transplacental effects of 3-azido-2, 3-dideoxythymidine (AZT): Tumorigenicity in mice and genotoxicity in mice and monkeys. J Natl Cancer Inst 1997; 89: 1602-1608
    • (1997) J Natl Cancer Inst , vol.89 , pp. 1602-1608
    • Olivero, O.A.1    Anderson, L.M.2    Diwan, B.A.3
  • 5
    • 4143074797 scopus 로고    scopus 로고
    • Perinatal genotoxicity and carcinogenicity of antiretroviral nucleoside analog drugs
    • Poirier MC, Olivero OA, Walker DM, Walker VE. Perinatal genotoxicity and carcinogenicity of antiretroviral nucleoside analog drugs. Toxicol Appl Pharmacol 2004; 199: 151-161
    • (2004) Toxicol Appl Pharmacol , vol.199 , pp. 151-161
    • Poirier, M.C.1    Olivero, O.A.2    Walker, D.M.3    Walker, V.E.4
  • 7
    • 67349173634 scopus 로고    scopus 로고
    • Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells
    • Borojerdi JP, Ming J, Cooch C,. et al. Centrosomal amplification and aneuploidy induced by the antiretroviral drug AZT in hamster and human cells. Mutat Res 2009; 665: 67-74
    • (2009) Mutat Res , vol.665 , pp. 67-74
    • Borojerdi, J.P.1    Ming, J.2    Cooch, C.3
  • 8
    • 55349084053 scopus 로고    scopus 로고
    • Incidence of cancer in children perinatally exposed to nucleoside reverse transcriptase inhibitors
    • Benhammou V, Warszawski J, Bellec S,. et al. Incidence of cancer in children perinatally exposed to nucleoside reverse transcriptase inhibitors. AIDS 2008; 22: 2165-2177
    • (2008) AIDS , vol.22 , pp. 2165-2177
    • Benhammou, V.1    Warszawski, J.2    Bellec, S.3
  • 9
    • 0028990381 scopus 로고
    • Mitochondrial toxicity of antiviral drugs
    • Lewis W, Dalakas MC. Mitochondrial toxicity of antiviral drugs. Nat Med 1995; 1: 417-422
    • (1995) Nat Med , vol.1 , pp. 417-422
    • Lewis, W.1    Dalakas, M.C.2
  • 11
    • 37549030898 scopus 로고    scopus 로고
    • HIV and mitochondrial toxicity in children
    • Foster C, Lyall H. HIV and mitochondrial toxicity in children. J Antimicrob Chemother 2008; 61: 8-12
    • (2008) J Antimicrob Chemother , vol.61 , pp. 8-12
    • Foster, C.1    Lyall, H.2
  • 12
    • 0038078685 scopus 로고    scopus 로고
    • Long-term mitochondrial toxicity in HIVuninfected infants born to HIV-infected mothers
    • Poirier MC, Divi RL, Al-Harthi L,. et al. Long-term mitochondrial toxicity in HIVuninfected infants born to HIV-infected mothers. J Acquir Immune Defic Syndr 2003; 33: 175-183
    • (2003) J Acquir Immune Defic Syndr , vol.33 , pp. 175-183
    • Poirier, M.C.1    Divi, R.L.2    Al-Harthi, L.3
  • 13
    • 2342613668 scopus 로고    scopus 로고
    • Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to combivir
    • Divi RL, Walker VE, Wade NA,. et al. Mitochondrial damage and DNA depletion in cord blood and umbilical cord from infants exposed in utero to combivir. AIDS 2004; 18: 1013-1021
    • (2004) AIDS , vol.18 , pp. 1013-1021
    • Divi, R.L.1    Walker, V.E.2    Wade, N.A.3
  • 14
    • 34247609876 scopus 로고    scopus 로고
    • In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children
    • Brogly SB, Ylitalo N, Mofenson LM,. et al. In utero nucleoside reverse transcriptase inhibitor exposure and signs of possible mitochondrial dysfunction in HIV-uninfected children. AIDS 2007; 21: 929-938
    • (2007) AIDS , vol.21 , pp. 929-938
    • Brogly, S.B.1    Ylitalo, N.2    Mofenson, L.M.3
  • 15
    • 37449023151 scopus 로고    scopus 로고
    • Metabolism and pharmacokinetics of the combination zidovudine plus lamivudine in the adult Erythrocebus patas monkey determined by liquid chromatography-tandem mass spectrometric analysis
    • Divi RL, Doerge DR, Twaddle NC,. et al. Metabolism and pharmacokinetics of the combination zidovudine plus lamivudine in the adult Erythrocebus patas monkey determined by liquid chromatography-tandem mass spectrometric analysis. Toxicol Appl Pharmacol 2008; 226: 206-211
    • (2008) Toxicol Appl Pharmacol , vol.226 , pp. 206-211
    • Divi, R.L.1    Doerge, D.R.2    Twaddle, N.C.3
  • 16
    • 84876906224 scopus 로고    scopus 로고
    • Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age
    • Olivero OA, Torres LR, Gorjifard S,. et al. Perinatal exposure of patas monkeys to antiretroviral nucleoside reverse-transcriptase inhibitors induces genotoxicity persistent for up to 3 years of age. J Infect Dis 2013; 208: 244-248
    • (2013) J Infect Dis , vol.208 , pp. 244-248
    • Olivero, O.A.1    Torres, L.R.2    Gorjifard, S.3
  • 17
    • 84876926913 scopus 로고    scopus 로고
    • Genotoxic signature in cord blood cells of newborns exposed in utero to a zidovudine-based antiretroviral combination
    • Andre-Schmutz I, Dal-Cortivo L, Six E,. et al. Genotoxic signature in cord blood cells of newborns exposed in utero to a zidovudine-based antiretroviral combination. J Infect Dis 2013; 208: 235-243
    • (2013) J Infect Dis , vol.208 , pp. 235-243
    • Andre-Schmutz, I.1    Dal-Cortivo, L.2    Six, E.3
  • 18
    • 78650534363 scopus 로고    scopus 로고
    • Cardiac effects of antiretroviral therapy in HIV-negative infants born to HIV-positive mothers: NHLBI CHAART-1 (National Heart, Lung, and Blood Institute cardiovascular status of HAART therapy in HIV-exposed infants and children cohort study)
    • Lipshultz SE, Shearer WT, Thompson B,. et al. Cardiac effects of antiretroviral therapy in HIV-negative infants born to HIV-positive mothers: NHLBI CHAART-1 (National Heart, Lung, and Blood Institute cardiovascular status of HAART therapy in HIV-exposed infants and children cohort study). J Am Coll Cardiol 2011; 57: 76-85
    • (2011) J Am Coll Cardiol , vol.57 , pp. 76-85
    • Lipshultz, S.E.1    Shearer, W.T.2    Thompson, B.3
  • 19
    • 84863204919 scopus 로고    scopus 로고
    • HAART to heart: Highly active antiretroviral therapy and the risk of cardiovascular disease inHIV-infected or exposed children and adults
    • Lipshultz SE, Mas CM, Henkel JM,. et al. HAART to heart: Highly active antiretroviral therapy and the risk of cardiovascular disease inHIV-infected or exposed children and adults. Expert Rev Anti Infect Ther 2012; 10: 661-674
    • (2012) Expert Rev Anti Infect Ther , vol.10 , pp. 661-674
    • Lipshultz, S.E.1    Mas, C.M.2    Henkel, J.M.3
  • 20
    • 84887299913 scopus 로고    scopus 로고
    • Cardiac effects in perinatally HIV-infected and HIV-exposed but uninfected children and adolescents: A view from the United States of America
    • Lipshultz SE, Miller TL, Wilkinson JD,. et al. Cardiac effects in perinatally HIV-infected and HIV-exposed but uninfected children and adolescents: A view from the United States of America. J Int AIDS Soc 2013; 16: 18597
    • (2013) J Int AIDS Soc , vol.16 , pp. 18597
    • Lipshultz, S.E.1    Miller, T.L.2    Wilkinson, J.D.3
  • 21
    • 84879111349 scopus 로고    scopus 로고
    • Cardiac biomarkers in HIV-exposed uninfected children
    • Wilkinson JD, Williams PL, Leister E,. et al. Cardiac biomarkers in HIV-exposed uninfected children. AIDS 2013; 27: 1099-1108
    • (2013) AIDS , vol.27 , pp. 1099-1108
    • Wilkinson, J.D.1    Williams, P.L.2    Leister, E.3
  • 22
    • 81855164872 scopus 로고    scopus 로고
    • Point-of-care capillary blood lactate measurements in human immunodeficiency virus-uninfected children with in utero exposure to human immunodeficiency virus and antiretroviral medications
    • Crain MJ, Williams PL, Griner R,. et al. Point-of-care capillary blood lactate measurements in human immunodeficiency virus-uninfected children with in utero exposure to human immunodeficiency virus and antiretroviral medications. Pediatr Infect Dis J 2011; 30: 1069-1074
    • (2011) Pediatr Infect Dis J , vol.30 , pp. 1069-1074
    • Crain, M.J.1    Williams, P.L.2    Griner, R.3
  • 23
    • 84905665102 scopus 로고    scopus 로고
    • Neurodevelopmental outcomes in HIVexposed-uninfected children versus those not exposed to HIV
    • Kerr SJ, Puthanakit T, Vibol U,. et al. Neurodevelopmental outcomes in HIVexposed-uninfected children versus those not exposed to HIV. AIDS Care 2014; 26: 1327-1335
    • (2014) AIDS Care , vol.26 , pp. 1327-1335
    • Kerr, S.J.1    Puthanakit, T.2    Vibol, U.3
  • 24
    • 84895543791 scopus 로고    scopus 로고
    • HIV-exposed uninfected children: A growing population with a vulnerable immune system?
    • Afran L, Garcia Knight M, Nduati E,. et al. HIV-exposed uninfected children: A growing population with a vulnerable immune system?. Clin Exp Immunol 2014; 176: 11-22
    • (2014) Clin Exp Immunol , vol.176 , pp. 11-22
    • Afran, L.1    Garcia Knight, M.2    Nduati, E.3
  • 25
    • 84922391640 scopus 로고    scopus 로고
    • Altered innate immune development in HIV-exposed uninfected infants
    • Reikie BA, Adams RC, Leligdowicz A,. et al. Altered innate immune development in HIV-exposed uninfected infants. J Acquir Immune Defic Syndr 2014; 66: 245-255
    • (2014) J Acquir Immune Defic Syndr , vol.66 , pp. 245-255
    • Reikie, B.A.1    Adams, R.C.2    Leligdowicz, A.3
  • 26
    • 34047235999 scopus 로고    scopus 로고
    • Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity
    • Divi RL, Leonard SL, Kuo MM,. et al. Transplacentally exposed human and monkey newborn infants show similar evidence of nucleoside reverse transcriptase inhibitor-induced mitochondrial toxicity. Environ Mol Mutagen 2007; 48: 201-209
    • (2007) Environ Mol Mutagen , vol.48 , pp. 201-209
    • Divi, R.L.1    Leonard, S.L.2    Kuo, M.M.3
  • 27
    • 79953755706 scopus 로고    scopus 로고
    • Quality assessment of human mitochondrial DNA quantification: Mitonauts, an international multicentre survey
    • Cote HC, Gerschenson M, Walker UA,. et al. Quality assessment of human mitochondrial DNA quantification: mitonauts, an international multicentre survey. Mitochondrion 2011; 11: 520-527
    • (2011) Mitochondrion , vol.11 , pp. 520-527
    • Cote, H.C.1    Gerschenson, M.2    Walker, U.A.3
  • 28
    • 67649194801 scopus 로고    scopus 로고
    • Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapy
    • Gingelmaier A, Grubert TA, Kost BP,. et al. Mitochondrial toxicity in HIV type-1-exposed pregnancies in the era of highly active antiretroviral therapy. Antivir Ther 2009; 14: 331-338
    • (2009) Antivir Ther , vol.14 , pp. 331-338
    • Gingelmaier, A.1    Grubert, T.A.2    Kost, B.P.3
  • 29
    • 84855353782 scopus 로고    scopus 로고
    • Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress
    • Ross AC, Leong T, Avery A,. et al. Effects of in utero antiretroviral exposure on mitochondrial DNA levels, mitochondrial function and oxidative stress. HIV medicine 2012; 13: 98-106
    • (2012) HIV Medicine , vol.13 , pp. 98-106
    • Ross, A.C.1    Leong, T.2    Avery, A.3
  • 30
    • 77958479044 scopus 로고    scopus 로고
    • Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs)
    • Divi RL, Einem TL, Fletcher SL,. et al. Progressive mitochondrial compromise in brains and livers of primates exposed in utero to nucleoside reverse transcriptase inhibitors (NRTIs). Toxicol Sci 2010; 118: 191-201
    • (2010) Toxicol Sci , vol.118 , pp. 191-201
    • Divi, R.L.1    Einem, T.L.2    Fletcher, S.L.3
  • 31
    • 27144536621 scopus 로고    scopus 로고
    • Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors
    • Divi RL, Leonard SL, Kuo MM,. et al. Cardiac mitochondrial compromise in 1-yr-old Erythrocebus patas monkeys perinatally-exposed to nucleoside reverse transcriptase inhibitors. Cardiovasc Toxicol 2005; 5: 333-346
    • (2005) Cardiovasc Toxicol , vol.5 , pp. 333-346
    • Divi, R.L.1    Leonard, S.L.2    Kuo, M.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.