The association of lectin-like oxidized LDL receptor 1 (LOX-1) K167N and 3′UTR188CT polymorphisms with maternal plasma soluble LOX-1 levels and preeclampsia risk in Turkish population

Archives of Gynecology and Obstetrics

Volumn 291, Issue 3, 2015, Pages 563-571

  Tuten, Abdullah ^a   Aydemir, Birsen ^b   Oncul, Mahmut ^a   Kiziler, Ali Riza ^c   Acıkgoz, Abdullah Serdar ^a   Korkmaz, Gulcan Guntas ^d   Sozer, Volkan ^e   Uzun, Hafize ^f  

^a ISTANBUL UNIVERSITY   (Turkey)

^b SAKARYA UNIVERSITY   (Turkey)

^c NAMIK KEMAL UNIVERSITY   (Turkey)

^d KIRKLARELI UNIVERSITY   (Turkey)

^e YILDIZ TECHNICAL UNIVERSITY   (Turkey)

^f ISTANBUL UNIVERSITY   (Turkey)

Author keywords

Lectin like oxidized LDL receptor 1 gene polymorphism; Oxidized LDL; Preeclampsia; Soluble lectin like oxidized LDL receptor 1

Indexed keywords

OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; 3' UNTRANSLATED REGION; LECTIN; LOW DENSITY LIPOPROTEIN; OXIDIZED LOW DENSITY LIPOPROTEIN;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENE FUNCTION; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; LOX 1 GENE; MAJOR CLINICAL STUDY; MATERNAL PLASMA; POLYMERASE CHAIN REACTION; PREECLAMPSIA; PROTEIN BLOOD LEVEL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; TURK (PEOPLE); 3' UNTRANSLATED REGION; BLOOD; EPIDEMIOLOGY; ETHNOLOGY; GENETICS; MATERNAL SERUM SCREENING TEST; MIDDLE AGED; PREGNANCY; RISK; TURKEY;

3' UNTRANSLATED REGIONS; ADULT; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HUMANS; LECTINS; LIPOPROTEINS, LDL; MATERNAL SERUM SCREENING TESTS; MIDDLE AGED; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; POLYMORPHISM, SINGLE NUCLEOTIDE; PRE-ECLAMPSIA; PREGNANCY; RISK; SCAVENGER RECEPTORS, CLASS E; TURKEY;

EID: 84922263574     PISSN: 09320067     EISSN: 14320711     Source Type: Journal    
DOI: 10.1007/s00404-014-3457-4     Document Type: Article

References (38)

1. Lima VJ, Andrade CR, Ruschi GE, Sass N (2011) Serum lipid levels in pregnancies complicated by preeclampsia. Sao Paulo Med J 129:73–76
2. Koga K, Izumi G, Mor G, Fujii T, Osuga Y (2014) Toll-like receptors at the maternal–fetal interface in normal pregnancy and pregnancy complications. Am J Reprod Immunol. doi:10.1111/aji.12258
3. Yin G, Zhu X, Guo C, Yang Y, Han T, Chen L, Yin W, Gao P, Zhang H, Geng J, Wang J, Liang L (2013) Differential expression of estradiol and estrogen receptor α in severe preeclamptic pregnancies compared with normal pregnancies. Mol Med Rep. 7(3):981–985
4. Cobellis L, De Falco M, Mastrogiacomo A, Giraldi D, Dattilo D, Scaffa C, Colacurci N, De Luca A (2007) Modulation of apelin and APJ receptor in normal and preeclampsia-complicated placentas. Histol Histopathol 22:1–8
5. Sahay AS, Patil VV, Sundrani DP, Joshi AA, Wagh GN, Gupte SA, Joshi SR (2014) A longitudinal study of circulating angiogenic and antiangiogenic factors and AT1-AA levels in preeclampsia. Hypertens Res. doi:10.1038/hr.2014.71
6. Inoue N, Fujita Y, Sawamura T (2006) Progress in the research on LOX-1 and its clinical relevance. Nihon Yakurigaku Zasshi 127:103–108
7. Al-Banna N, Lehmann C (2013) Oxidized LDL and LOX-1 in experimental sepsis. Mediators Inflamm 2013:761789
8. Fujita Y, Kakino A, Nishimichi N, Yamaguchi S, Sato Y, Machida S, Cominacini L, Delneste Y, Matsuda H, Sawamura T (2009) Oxidized LDL receptor LOX-1 binds to C-reactive protein and mediates its vascular effects. Clin Chem 55(2):285–294
9. Hou XW, Son J, Wang Y, Ru YX, Lian Q, Majiti W, Amazouzi A, Zhou YL, Wang PX, Han ZC (2006) Granulocyte colony-stimulating factor reduces cardiomyocyte apoptosis and improves cardiac function in adriamycin-induced cardiomyopathy in rats. Cardiovasc Drugs Ther 20(2):85–91
10. Morawietz H, Rueckschloss U, Niemann B, Duerrschmidt N, Galle J, Hakim K, Zerkowski HR, Sawamura T, Holtz J (1999) Angiotensin II induces LOX-1, the human endothelial receptor for oxidized low-density lipoprotein. Circulation 100(9):899–902
11. Predazzi IM, Norata GD, Vecchione L, Garlaschelli K, Amati F, Grigore L, Cutuli L, Pirillo A, Tramontana S, Romeo F, Novelli G, Catapano AL (2012) Association between OLR1 K167N SNP and intima media thickness of the common carotid artery in the general population. PLoS ONE 7(2):e31086. doi:10.1371/journal.pone.0031086
12. Kume N, Kita T (2001) Roles of lectin-like oxidized LDL receptor-1 and its soluble forms in atherogenesis. Curr Opin Lipidol 12:419–423
13. Morawietz H (2010) LOX-1 receptor as a novel target in endothelial dysfunction and atherosclerosis. Dtsch Med Wochenschr 135:308–312
14. Yamanaka S, Zhang XY, Miura K, Kim S, Iwao H (1998) The human gene encoding the lectin-type oxidized LDL receptor (OLR1) is a novel member of the natural killer gene complex with a unique expression profile. Genomics 54:191–199
15. ACOG practice bulletin (2002) Diagnosis and management of preeclampsia and eclampsia. Obstet Gynecol 99:159–167
16. Trabetti E, Biscuola M, Cavallari U, Malerba G, Girelli D, Olivieri O, Martinelli N, Corrocher R, Pignatti PF (2006) On the association of the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction or coronary artery disease. Eur J Hum Genet 14:127–130
17. Chen Q, Reis SE, Kammerer C, Craig WY, LaPierre SE, Zimmer EL, McNamara DM, Pauly DF, Sharaf B, Holubkov R, Bairey Merz CN, Sopko G, Bontempo F, Kamboh MI (2003) Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1 (LOX1) gene and the risk of coronary artery disease. Circulation 107:3146–3151
18. Tatsuguchi M, Furutani M, Hinagata J, Tanaka T, Furutani Y, Imamura S, Kawana M, Masaki T, Kasanuki H, Sawamura T, Matsuoka R (2003) Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction. Biochem Biophys Res Commun. 303(1):247–250
19. Hou XW, Yang RQ, Zhong YG, Gao W, Sun SP, Wang NF (2011) G501C polymorphism of the oxidized LDL receptor gene is associated with albuminuria in Chinese essential hypertension patients. Genet Mol Res 10(4)
20. Kurnaz O, Aydogan HY, Isbir CS, Tekeli A, Isbir T (2009) Is LOX-1 K167N polymorphism protective for coronary artery disease? In Vivo 23(6):969–973
21. Xu X, Hou X, Liang Y, Li F, Pang L, Huang G, Huang J, Shi M, Sun X, Wang Y (2014) The gene polymorphism of LOX1 predicts the incidence of LVH in patients with essential hypertension. Cell Physiol Biochem 33(1):88–96
22. Ohki I, Ishigaki T, Oyama T, Matsunaga S, Xie Q, Ohnishi-Kameyama M, Murata T, Tsuchiya D, Machida S, Morikawa K, Tate S (2005) Crystal structure of human lectin-like, oxidized low-density lipoprotein receptor 1 ligand binding domain and its ligand recognition mode to OxLDL. Structure 13(6):905–917
23. Chen M, Inoue K, Narumiya S, Masaki T, Sawamura T (2001) Requirements of basic amino acid residues within the lectin-like domain of LOX-1 for the binding of oxidized low-density lipoprotein. FEBS Lett 499(3):215–219
24. Kurnaz O, Akadam-Teker AB, Yilmaz-Aydoğan H, Tekeli A, Isbir T (2012) The LOX-1 3′UTR188CT polymorphism and coronary artery disease in Turkish patients. Mol Biol Rep 39(4):4351–4358
25. Mango R, Clementi F, Borgiani P, Forleo GB, Federici M, Contino G, Giardina E, Garza L, Fahdi IE, Lauro R, Mehta JL, Novelli G, Romeo F (2003) Association of single nucleotide polymorphisms in the oxidised LDL receptor 1 (OLR1) gene in patients with acute myocardial infarction. J Med Genet 40:933–936
26. Sentinelli F, Filippi E, Fallarino M, Romeo S, Fanelli M, Buzzetti R, Berni A, Baroni MG (2006) The 3′-UTR C>T polymorphism of the oxidized LDL-receptor 1 (OLR1) gene does not associate with coronary artery disease in Italian CAD patients or with the severity of coronary disease. Nutr Metab Cardiovasc Dis 16:345–352
27. Brinkley TE, Kume N, Mitsuoka H, Brown MD, Phares DA, Ferrell RE, Kita T, Hagberg JM (2008) Variation in the human lectin-like oxidized low-density lipoprotein receptor 1 (LOX-1) gene is associated with plasma soluble LOX-1 levels. Exp Physiol 93(9):1085–1090
28. Mango R, Biocca S, del Vecchio F, Clementi F, Sangiuolo F, Amati F, Filareto A, Grelli S, Spitalieri P, Filesi I, Favalli C, Lauro R, Mehta JL, Romeo F, Novelli G (2005) In vivo and in vitro studies support that a new splicing isoform of OLR1 gene is protective against acute myocardial infarction. Circ Res 97(2):152–158
29. Palmieri VO, Coppola B, Grattagliano I, Casieri V, Cardinale G, Portincasa P, Palasciano G, Di Serio F (2013) Oxidized LDL receptor 1 gene polymorphism in patients with metabolic syndrome. Eur J Clin Invest 43:41–48
30. Lee H, Park H, Kim YJ, Kim HJ, Ahn YM, Park B, Park JH, Lee BE (2005) Expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in human preeclamptic placenta: possible implications in the process of trophoblast apoptosis. Placenta 26:226–233
31. Mehta JL, Li DY (1998) Identification and autoregulation of receptor for OX-LDL in cultured human coronary artery endothelial cells. Biochem Biophys Res Commun 248:511–514
32. Mitra S, Goyal T, Mehta JL (2011) Oxidized LDL, LOX-1 and atherosclerosis. Cardiovasc Drugs Ther 25:419–429
33. Uzun H, Benian A, Madazli R, Topçuoğlu MA, Aydin S, Albayrak M (2005) Circulating oxidized low-density lipoprotein and paraoxonase activity in preeclampsia. Gynecol Obstet Invest 60:195–200
34. English FA, McCarthy FP, McSweeney CL, Quon AL, Morton JS, Sawamura T, Davidge ST, Kenny LC (2013) Inhibition of lectin-like oxidized low-density lipoprotein-1 receptor protects against plasma-mediated vascular dysfunction associated with pre-eclampsia. Am J Hypertens 26:279–286
35. Chigusa Y, Tatsumi K, Kondoh E, Fujita K, Nishimura F, Mogami H, Konishi I (2012) Decreased lectin-like oxidized LDL receptor 1 (LOX-1) and low Nrf2 activation in placenta are involved in preeclampsia. J Clin Endocrinol Metab 97:E1862–E1870
36. Murase T, Kume N, Kataoka H, Minami M, Sawamura T, Masaki T, Kita T (2000) Identification of soluble forms of lectin-like oxidized LDL receptor-1. Arterioscler Thromb Vasc Biol 20:715–720
37. Ohmori R, Momiyama Y, Nagano M, Taniguchi H, Egashira T, Yonemura A, Nakamura H, Kondo K, Ohsuzu F (2004) An oxidized low-density lipoprotein receptor gene variant is inversely associated with the severity of coronary artery disease. Clin Cardiol 27(11):641–644
38. Hayashida K, Kume N, Murase T, Minami M, Nakagawa D, Inada T, Tanaka M, Ueda A, Kominami G, Kambara H, Kimura T, Kita T (2005) Serum soluble lectin-like oxidized low-density lipoprotein receptor-1 levels are elevated in acute coronary syndrome: a novel marker for early diagnosis. Circulation 112:812–818