Balancing oxygen diffusion and convection in spiral microfluidics to mimic radial biological gradients

Biomedical Microdevices

Volumn 17, Issue 1, 2015, Pages

  Li, Zidong ^a   Hu, Di ^a   Zhao, Zhengtuo ^a   Zhou, Mengyang ^a   Liu, Rui ^a   Lo, Joe F ^a  

^a University of Michigan Dearborn   (United States)

Author keywords

Convection; Diffusion; Fibroblast; Hypoxia; Microfluidic; Oxygen; Spatial gradient; VEGF secretion

Indexed keywords

CELL CULTURE; DIFFUSION; DIFFUSION IN GASES; FIBROBLASTS; GAS PERMEABLE MEMBRANES; HEAT CONVECTION; OXYGEN; TISSUE; TISSUE REGENERATION;

FIBROBLAST CELLS; HYPOXIA; OXYGEN DIFFUSION; RADIAL GEOMETRIES; SOFT LITHOGRAPHY; SPATIAL GRADIENTS; SPATIAL RESPONSE; VEGF SECRETIONS;

MICROFLUIDICS;

OXYGEN; VASCULOTROPIN; BIOMIMETIC MATERIAL; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ANGIOGENESIS; ARTICLE; CELL MIGRATION; FIBROBLAST; HYPOXEMIA; HYPOXIA; IN VITRO STUDY; MEMBRANE PERMEABILITY; MICROFLUIDICS; OXYGEN DIFFUSION; PRIORITY JOURNAL; ROBOTICS; THERMODYNAMICS; WOUND HEALING; CELL HYPOXIA; DEVICES; INJURY; METABOLISM; MICROFLUIDIC ANALYSIS; PATHOLOGY; PROCEDURES; SECRETION (PROCESS);

BIOMIMETIC MATERIALS; CELL HYPOXIA; FIBROBLASTS; MICROFLUIDIC ANALYTICAL TECHNIQUES; OXYGEN; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUNDS AND INJURIES;

EID: 84922259310     PISSN: 13872176     EISSN: 15728781     Source Type: Journal    
DOI: 10.1007/s10544-014-9922-9     Document Type: Article

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