Analysis of Individual Protein Regions Provides Novel Insights on Cancer Pharmacogenomics

PLoS Computational Biology

Volumn 11, Issue 1, 2015, Pages

  Pardo, Eduard Porta ^a   Godzik, Adam ^a  

^a BURNHAM INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; DISEASES; GENOME; PROTEINS;

ANTICANCER DRUG; CANCER CELL LINES; DRUG-SENSITIVITY; GENOMIC ALTERATIONS; GENOMICS; INDIVIDUAL PROTEINS; INTRINSICALLY DISORDERED REGIONS; NOVEL ASSOCIATIONS; PHARMACOGENOMICS; PROTEIN DOMAINS;

GENES;

ANTINEOPLASTIC AGENT; ERLOTINIB; IRINOTECAN; PACLITAXEL; PROTEIN; SELUMETINIB; TOPOTECAN; PROTEIN BINDING;

ARTICLE; CANCER CELL LINE; CANCER PATIENT; CANCER RESISTANCE; CHEMOSENSITIVITY; CONTROLLED STUDY; GENE INACTIVATION; GENE SILENCING; HUMAN; HUMAN CELL; MISSENSE MUTATION; MUTATIONAL ANALYSIS; PHARMACOGENOMICS; PREDICTION; PROTEIN ANALYSIS; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN FUNCTIONAL REGION; PROTEIN STRUCTURE; VALIDATION PROCESS; CHEMISTRY; GENETIC DATABASE; GENETICS; METABOLISM; MUTATION; PERSONALIZED MEDICINE; PHARMACOGENETICS; PHYSIOLOGY; PROCEDURES; PROTEIN PROTEIN INTERACTION; PROTEIN TERTIARY STRUCTURE; SURVIVAL; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DATABASES, GENETIC; HUMANS; MUTATION; PHARMACOGENETICS; PRECISION MEDICINE; PROTEIN BINDING; PROTEIN INTERACTION MAPS; PROTEIN STRUCTURE, TERTIARY; PROTEINS; SURVIVAL ANALYSIS;

EID: 84922250630     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1004024     Document Type: Article

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