Possible recurrence of symptoms after discontinuation of omalizumab in anti-IgE-assisted desensitization to egg

Pediatric Allergy and Immunology

Volumn 25, Issue 7, 2014, Pages 717-719

  Lafuente, Isabel ^a   Mazon, Angel ^a   Nieto, Maria ^a   Uixera, Sonia ^a   Pina, Raquel ^a   Nieto, Antonio ^a  

^a INSTITUTO DE INVESTIGACIÓN SANITARIA DEL HOSPITAL CLÍNICO SAN CARLOS IDISSC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

EGG WHITE; IMMUNOGLOBULIN E ANTIBODY; OMALIZUMAB; OVALBUMIN; OVOMUCOID; ALLERGEN; ANTIIDIOTYPIC ANTIBODY; IMMUNOGLOBULIN E; MONOCLONAL ANTIBODY;

ABDOMINAL PAIN; ARTICLE; CASE REPORT; CHILD; CHILDHOOD DISEASE; DESENSITIZATION; DRUG WITHDRAWAL; EGG ALLERGY; FEMALE; HUMAN; INFORMED CONSENT; MAINTENANCE DRUG DOSE; ORAL PRURITUS; PRIORITY JOURNAL; PROVOCATION TEST; RECOMMENDED DRUG DOSE; RECURRENT DISEASE; SCHOOL CHILD; SKIN TEST; TREATMENT DURATION; VOMITING; BLOOD; EGG HYPERSENSITIVITY; IMMUNOLOGY; INFANT; OOCYTE; PROCEDURES; TREATMENT OUTCOME; TREATMENT WITHDRAWAL;

ALLERGENS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, MONOCLONAL, HUMANIZED; CHILD; DESENSITIZATION, IMMUNOLOGIC; EGG HYPERSENSITIVITY; FEMALE; HUMANS; IMMUNOGLOBULIN E; INFANT; OVOMUCIN; OVUM; RECURRENCE; TREATMENT OUTCOME; WITHHOLDING TREATMENT;

EID: 84922248285     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/pai.12259     Document Type: Article

References (10)

1. Staden U, Rolinck-Werninghaus C, Brewe F, Wahn U, Niggemann B, Beyer K. Specific oral tolerance induction in food allergy in children: efficacy and clinical patterns of reaction. Allergy 2007: 62: 1261-9.
2. Garcia RR, Urra JM, Feo-Brito F, et al. Oral rush desensitization to egg: efficacy and safety. Clin Exp Allergy 2011: 41: 1289-96.
3. Nadeau KC, Schneider LC, Hoyte L, Borras I, Umetsu DT. Rapid oral desensitization in combination with omalizumab therapy in patients with cow's milk allergy. J Allergy Clin Immunol 2011: 127: 1622-4.
4. Schneider LC, Rachid R, LeBovidge J, Blood E, Mittal M, Umetsu DT. A pilot study of omalizumab to facilitate rapid oral desensitization in high-risk peanut-allergic patients. J Allergy Clin Immunol 2013: 132: 1367-74.
5. Bedoret D, Singh AK, Shaw V, et al. Changes in antigen-specific T cell number and function during oral desensitization in cow's milk allergy enabled with omalizumab. Mucosal Immunol 2012: 5: 267-76.
6. Bégin P, Dominguez T, Wilson SP, et al. Phase 1 results of safety and tolerability in a rush oral immunotherapy protocol to multiple foods using Omalizumab. Allergy Asthma Clin Immunol 2014: 10: 7.
7. Buchanan AD, Green TD, Jones SM, et al. Egg oral immunotherapy in nonanaphylactic children with egg allergy. J Allergy Clin Immunol 2007: 119: 199-205.
8. Lowe PJ, Renard D. Omalizumab decreases IgE production in patients with allergic (IgE-mediated) asthma; PKPD analysis of a biomarker, total IgE. Br J Clin Pharmacol 2011: 72: 306-20.
9. Djukanovic R, Wilson SJ, Kraft M, et al. Effects of treatment with anti-immunoglobulin E antibody omalizumab on airway inflammation in allergic asthma. Am J Respir Crit Care Med 2004: 170: 583-93.
10. Morisset M, Moneret-Vautrin DA, Guenard L, et al. Oral desensitization in children with milk and egg allergies obtains recovery in a significant proportion of cases. A randomized study in 60 children with cow's milk allergy and 90 children with egg allergy. Eur Ann Allergy Clin Immunol 2007: 39: 9-12.