Reference range determination for whole-blood platelet aggregation using the multiplate analyzer

American Journal of Clinical Pathology

Volumn 142, Issue 5, 2014, Pages 647-656

  Peerschke, Ellinor I B ^a   Castellone, Donna D ^b   Stroobants, A K ^c   Francis, John ^d  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Roche Diagnostics Corporation   (United States)

^c ACADEMIC MEDICAL CENTER   (Netherlands)

^d FLORIDA HOSPITAL   (United States)

Author keywords

Aggregation; Anticoagulants; Multiplate; Platelets; Precision; Reference range

Indexed keywords

ACETYLSALICYLIC ACID; ADENOSINE DIPHOSPHATE; ARACHIDONIC ACID; CITRATE SODIUM; COLLAGEN; HEPARIN; HIRUDIN; LITHIUM; PROSTAGLANDIN E1; RISTOCETIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; CITRIC ACID; HIRUDIN DERIVATIVE;

ACCURACY; ADULT; AGED; ANTICOAGULANT THERAPY; AREA UNDER THE CURVE; ARTICLE; ASIAN; BLOOD ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; ETHNIC DIFFERENCE; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MULTICENTER STUDY; NORMAL HUMAN; PRIORITY JOURNAL; PROSPECTIVE STUDY; REFERENCE VALUE; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; THROMBOCYTE FUNCTION ANALYZER; WHOLE BLOOD PLATELET AGGREGATION; BLOOD CLOTTING PARAMETERS; CYTOLOGY; DEVICES; DRUG EFFECTS; MIDDLE AGED; STANDARD; STANDARDS; THROMBOCYTE; YOUNG ADULT;

ADULT; AGED; ANTICOAGULANTS; BLOOD PLATELETS; CITRATES; FEMALE; HEPARIN; HIRUDINS; HUMANS; MALE; MIDDLE AGED; PLATELET AGGREGATION; PLATELET AGGREGATION INHIBITORS; PLATELET FUNCTION TESTS; REFERENCE STANDARDS; REFERENCE VALUES; YOUNG ADULT;

EID: 84922220425     PISSN: 00029173     EISSN: 19437722     Source Type: Journal    
DOI: 10.1309/AJCPP43SEYCBJLHJ     Document Type: Article

References (24)

1. Harrison P. Assessment of platelet function in the laboratory. Hamostaseologie. 2009;29:25-31.
2. Breddin HK. Can platelet aggregation be standardized? Platelets. 2005;16:151-158.
3. Breddin K, Ziemen M, Bauer O, et al. Time and temperature dependent changes of ADP and collagen inducted and spontaneous aggregation. Thromb Res. 1980;19:621-638.
4. Harrison P. Progress in the assessment of platelet function. Br J Haematol. 2000;111:733-744.
5. Reiss H, Braun G, Brehm B, et al. Critical evaluation of platelet aggregation in whole blood. Am J Clin Pathol. 1986;85:50-56.
6. Walln H, Ladjevardi M, Albertb J, et al. Anticoagulants used for platelet function studies in vitro may affect platelet responsiveness: influence of different anticoagulants on platelet aggregation in whole blood; a comparison between citrate, low molecular mass heparin and hirudin. Thromb Res. 1997;87:151-157.
7. Kroll MH, Schafer A. Biochemical mechanisms of platelet activation. Blood. 1989;74:181-195.
8. Rubak P, Villadse K, Hvas A. Reference intervals for platelet aggregation assessed by Multiplate electrode platelet aggregometry. Thromb Res. 2012;130:420-423.
9. Glusa E, Markwardt F. Platelet function in recombinant hirudin anticoagulated blood. Haemostasis. 1990;20:112-118.
10. Xia Z, Therouz P. Platelet activation with unfractionated heparin at therapeutic concentrations and comparison with a low molecular weight heparin and with a direct thrombin inhibitor. Circulation. 1998;97:251-256.
11. Golanski J, Peitricha T, Baj Z, et al. Molecular insights into the anticoagulant induced spontaneous activation of platelets in whole-blood, various anticoagulants are not equal. Thromb Res. 1996;3:199-216.
12. Clinical Laboratory and Standards Institute (CLSI). EP15-A2: User Verification of Performance for Precision and Trueness. Wayne, PA: CLSI; 2006.
13. Clinical Laboratory and Standards Institute (CLSI). H58-A: Platelet Function Testing by Aggregometry. Wayne, PA: CLSI; 2008.
14. Hevelow ME, McKenzie SM, Siegel JE. Reproducibility of platelet function testing. Lab Hematol. 2007;13:59-62.
15. Basic-Micic M, Rauschenbach C, Demgen G, et al. Antikoagulans zur Untersuchung der Thrombozytenfunktion. Hamostaseologie. 1991;1:114-121.
16. Zhang HZ, Yu LH, Kim MH. Effect of different anticoagulants on multiple electrode platelet aggregometry after clopidogrel and aspirin administration in patients undergoing coronary stent implantation: a comparison between citrate and hirudin. Platelets. 2013;24:339-347.
17. Truss NJ, Armstrong CJ, Liverani E, et al. Heparin but not citrate anticoagulation of blood preserves platelet function for prolonged periods. J Thromb Haemost. 2009,7:1897-1905.
18. Fitzgerald LA, Philips DR. Calcium regulation of the platelet membrane glycoprotein IIb/IIIa. J Biol Chem. 1985;260:11366-11377.
19. Schneider D, Tracy P, Mann K, et al. Differential effects of anticoagulants on the activation of platelets ex vivo. Circulation. 1997;96:2877-2883.
20. Kalb M, Potura, Scharvert G, et al, The effect of ex vivo anticoagulants on whole blood platelet aggregation. Platelets. 2009;20:7-11.
21. Johnston LR, Larson PD, LaFlamme AC, et al. Methodological consideration for the assessment of ADP induced platelet aggregation using Multiplate analyzer. Platelets. 2013;24:303-307.
22. Kaiser A, Newbauer H, Franken C, et al. Which is the best anticoagulant for whole blood aggregometry platelet function testing? comparison of six anticoagulants and diverse storage conditions. Platelets. 2012;23:359-367.
23. deMeis L, Suzano VA. Uncoupling of muscle and blood platelet Ca2+ transport ATPases by heparin. J Biol Chem. 1994;269:14525-14529.
24. Chan MY. Clopidogrel pharmacogenetics of east, south and other Asian populations. Eur Heart J Suppl. 2012;14(suppl A):A41-A42.