ANEMIA;
AREA UNDER THE CURVE;
ARTICLE;
BIOAVAILABILITY;
DRUG ACTIVITY;
GENE EXPRESSION;
HUMAN;
IMMUNOBLOTTING;
INFLAMMATION;
MAXIMUM PLASMA CONCENTRATION;
QUANTITATIVE ANALYSIS;
REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;
RNA EXTRACTION;
TIME TO MAXIMUM PLASMA CONCENTRATION;
ANIMAL;
ANTAGONISTS AND INHIBITORS;
C57BL MOUSE;
CELL CULTURE;
CHEMICALLY INDUCED;
COMPLICATION;
FEMALE;
GENETICS;
METABOLISM;
MOUSE;
ORAL DRUG ADMINISTRATION;
REAL TIME POLYMERASE CHAIN REACTION;
TISSUE DISTRIBUTION;
WESTERN BLOTTING;
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
Babitt JL, Huang FW, Wrighting DM, et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet. 2006;38(5):531-539.
Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation
Steinbicker AU, Sachidanandan C, Vonner AJ, et al. Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation. Blood. 2011;117(18):4915-4923.
Pharmacologic inhibition of hepcidin expression reverses anemia of chronic inflammation in rats
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Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats
Theurl M, Nairz M, Schroll A, et al. Hepcidin as a predictive factor and therapeutic target in erythropoiesis-stimulating agent treatment for anemia of chronic disease in rats. Haematologica. 2014; 99(9):1516-1524.
Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism
Yu PB, Hong CC, Sachidanandan C, et al. Dorsomorphin inhibits BMP signals required for embryogenesis and iron metabolism. Nat Chem Biol. 2008;4(1):33-41.
IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
Nemeth E, Rivera S, Gabayan V, et al. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest. 2004;113(9):1271-1276.
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Late stage erythroid precursor production is impaired in mice with chronic inflammation
Prince OD, Langdon JM, Layman AJ, et al. Late stage erythroid precursor production is impaired in mice with chronic inflammation. Haematologica. 2012;97(11):1648-1656.
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A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats
Sun CC, Vaja V, Chen S, et al. A hepcidin lowering agent mobilizes iron for incorporation into red blood cells in an adenine-induced kidney disease model of anemia in rats. Nephrol Dial Transplant. 2013; 28(7):1733-1743.