Anti-N-methyl-D-aspartate receptor encephalitis that developed after herpes encephalitis: A case report and literature review

Neuropediatrics

Volumn 45, Issue 6, 2014, Pages 396-401

  Bektaş, Ömer ^a   Tanyel, Tutku ^b   Kocabaş, Bilge Aldemir ^a   Fitöz, Suat ^a   Ince, Erdal ^a   Deda, Gülhis ^a  

^a ANKARA UNIVERSITY   (Turkey)

^b Duzen Laboratory Groups   (Turkey)

Author keywords

autoimmune encephalitis; choreoathetoid movements; dyskinesia; herpes encephalitis; pediatric; relapse

Indexed keywords

ACICLOVIR; ACUTE PHASE PROTEIN; AMMONIA; ANTIBODY; CEFTRIAXONE; CHICKENPOX VACCINE; CYCLOPHOSPHAMIDE; ETIRACETAM; GLUCOSE; IMMUNOGLOBULIN; LACTIC ACID; METHYLPREDNISOLONE; MIDAZOLAM; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1; N METHYL DEXTRO ASPARTIC ACID RECEPTOR ANTIBODY; PHENOBARBITAL; PHENYTOIN; PREDNISOLONE; PROTEIN; RITUXIMAB; STEROID; UNCLASSIFIED DRUG; ANTIVIRUS AGENT;

ALLERGIC ENCEPHALITIS; AMMONIA BLOOD LEVEL; ANTI N METHYL D ASPARTATE RECEPTOR ENCEPHALITIS; ANTIBIOTIC THERAPY; ANTIBODY DETECTION; APHASIA; ARTICLE; BRAIN ATROPHY; CASE REPORT; CEREBROSPINAL FLUID ANALYSIS; CHILD; COMPUTER ASSISTED TOMOGRAPHY; CONSCIOUSNESS DISORDER; DRUG DOSE REDUCTION; DRUG PULSE THERAPY; FEMALE; FEVER; FOCAL EPILEPSY; FOLLOW UP; GLASGOW COMA SCALE; GLUCOSE BLOOD LEVEL; HALLUCINATION; HERPES SIMPLEX ENCEPHALITIS; HOSPITAL ADMISSION; HUMAN; HUMAN CELL; HYPERSALIVATION; IMMUNOTHERAPY; LACTATE BLOOD LEVEL; LUMBAR PUNCTURE; MICROSCOPY; MOTOR DYSFUNCTION; MULTIPLE CYCLE TREATMENT; NEUROIMAGING; NEUROLOGIC EXAMINATION; NUCLEAR MAGNETIC RESONANCE IMAGING; OROFACIAL DYSKINESIA; PARANEOPLASTIC NEUROPATHY; PHYSICAL EXAMINATION; PLASMAPHERESIS; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RECURRENT DISEASE; RETREATMENT; SEIZURE; STEROID THERAPY; TREATMENT RESPONSE; UNCONSCIOUSNESS; UPPER RESPIRATORY TRACT INFECTION; VACCINATION; ANTI-N-METHYL-D-ASPARTATE RECEPTOR ENCEPHALITIS; DISEASE COURSE; ENCEPHALITIS, HERPES SIMPLEX; INFANT; TREATMENT OUTCOME;

ACYCLOVIR; ANTI-N-METHYL-D-ASPARTATE RECEPTOR ENCEPHALITIS; ANTIVIRAL AGENTS; DISEASE PROGRESSION; ENCEPHALITIS, HERPES SIMPLEX; FEMALE; HUMANS; INFANT; STEROIDS; TREATMENT OUTCOME;

EID: 84922149591     PISSN: 0174304X     EISSN: 14391899     Source Type: Journal    
DOI: 10.1055/s-0034-1387813     Document Type: Article

References (23)

1. Steiner I., Kennedy P. G., Pachner A. R. The neurotropic herpes viruses: herpes simplex and varicella-zoster. Lancet Neurol: 2007; 6 11 1015 1028
2. Raschilas F., Wolff M., Delatour F., et al. Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study. Clin Infect Dis: 2002; 35 3 254 260
3. Prüss H., Finke C., Höltje M., et al. N-methyl-D-aspartate receptor antibodies in herpes simplex encephalitis. Ann Neurol: 2012; 72 6 902 911
4. Fiser D. H., Long N., Roberson P. K., Hefley G., Zolten K., Brodie-Fowler M. Relationship of pediatric overall performance category and pediatric cerebral performance category scores at pediatric intensive care unit discharge with outcome measures collected at hospital discharge and 1- and 6-month follow-up assessments. Crit Care Med: 2000; 28 7 2616 2620
5. Dalmau J., Gleichman A. J., Hughes E. G., et al. Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol: 2008; 7 12 1091 1098
6. Lai M., Hughes E. G., Peng X., et al. AMPA receptor antibodies in limbic encephalitis alter synaptic receptor location. Ann Neurol: 2009; 65 4 424 434
7. Lancaster E., Lai M., Peng X., et al. Antibodies to the GABA(B) receptor in limbic encephalitis with seizures: case series and characterisation of the antigen. Lancet Neurol: 2010; 9 1 67 76
8. Leypoldt F., Titulaer M. J., Aguilar E., et al. Herpes simplex virus-1 encephalitis can trigger anti-NMDA receptor encephalitis: case report. Neurology: 2013; 81 18 1637 1639
9. Armangue T., Titulaer M. J., Málaga I., et al. Spanish Anti-N-methyl-D-Aspartate Receptor (NMDAR) Encephalitis Work Group. Pediatric anti-N-methyl-D-aspartate receptor encephalitis-clinical analysis and novel findings in a series of 20 patients. J Pediatr: 2013; 162 4 850 856, e2
10. Hacohen Y., Deiva K., Pettingill P., et al. N-methyl-D-aspartate receptor antibodies in post-herpes simplex virus encephalitis neurological relapse. Mov Disord: 2014; 29 1 90 96
11. Armangue T., Leypoldt F., Málaga I., et al. Herpes simplex virus encephalitis is a trigger of brain autoimmunity. Ann Neurol: 2014; 75 2 317 323
12. Mohammad S. S., Sinclair K., Pillai S., et al. Herpes simplex encephalitis relapse with chorea is associated with autoantibodies to N-Methyl-D-aspartate receptor or dopamine-2 receptor. Mov Disord: 2014; 29 1 117 122
13. Florance N. R., Davis R. L., Lam C., et al. Anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis in children and adolescents. Ann Neurol: 2009; 66 1 11 18
14. Bseikri M. R., Barton J. R., Kulhanjian J. A., et al. Anti-N-methyl D-aspartate receptor encephalitis mimics viral encephalitis. Pediatr Infect Dis J: 2012; 31 2 202 204
15. Gable M. S., Sheriff H., Dalmau J., Tilley D. H., Glaser C. A. The frequency of autoimmune N-methyl-D-aspartate receptor encephalitis surpasses that of individual viral etiologies in young individuals enrolled in the California Encephalitis Project. Clin Infect Dis: 2012; 54 7 899 904
16. Sellner J., Dvorak F., Zhou Y., et al. Acute and long-term alteration of chemokine mRNA expression after anti-viral and anti-inflammatory treatment in herpes simplex virus encephalitis. Neurosci Lett: 2005; 374 3 197 202
17. Reiber H., Ungefehr S., Jacobi C. The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis. Mult Scler: 1998; 4 3 111 117
18. Titulaer M. J., McCracken L., Gabilondo I., et al. Treatment and prognostic factors for long-term outcome in patients with anti-NMDA receptor encephalitis: an observational cohort study. Lancet Neurol: 2013; 12 2 157 165
19. Hargrave D. R., Webb D. W. Movement disorders in association with herpes simplex virus encephalitis in children: a review. Dev Med Child Neurol: 1998; 40 9 640 642
20. De Tiège X., Rozenberg F., Des Portes V., et al. Herpes simplex encephalitis relapses in children: differentiation of two neurologic entities. Neurology: 2003; 61 2 241 243
21. De Tiège X., De Laet C., Mazoin N., et al. Postinfectious immune-mediated encephalitis after pediatric herpes simplex encephalitis. Brain Dev: 2005; 27 4 304 307
22. Sköldenberg B., Aurelius E., Hjalmarsson A., et al. Incidence and pathogenesis of clinical relapse after herpes simplex encephalitis in adults. J Neurol: 2006; 253 2 163 170
23. Meyding-Lamadé U. K., Oberlinner C., Rau P. R., et al. Experimental herpes simplex virus encephalitis: a combination therapy of acyclovir and glucocorticoids reduces long-term magnetic resonance imaging abnormalities. J Neurovirol: 2003; 9 1 118 125