N-methyl-D-aspartate receptor antibodies in herpes simplex encephalitis

Annals of Neurology

Volumn 72, Issue 6, 2012, Pages 902-911

  Prüss, Harald ^a   Finke, Carsten ^a   Höltje, Markus ^a   Hofmann, Joerg ^a   Klingbeil, Christine ^b   Probst, Christian ^b   Borowski, Kathrin ^b   Ahnert Hilger, Gudrun ^a   Harms, Lutz ^a   Schwab, Jan M ^a   Ploner, Christoph J ^a   Komorowski, Lars ^b   Stoecker, Winfried ^b   Dalmau, Josep ^c,d   Wandinger, Klaus Peter ^b,e  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b Institute of Experimental Immunology   (Germany)

^c UNIVERSITY OF BARCELONA   (Spain)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

^e UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; AUTOANTIBODY; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR ANTIBODY;

ADOLESCENT; ADULT; AGED; ANIMAL CELL; ANTIBODY PRODUCTION; ANTIVIRAL THERAPY; ARTICLE; AUTOIMMUNITY; BLOOD SAMPLING; BRAIN NERVE CELL; CELL STRAIN HEK293; CHILD; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; ELECTROENCEPHALOGRAPHY; FEMALE; FEVER; FOLLOW UP; HEADACHE; HERPES SIMPLEX ENCEPHALITIS; HERPES ZOSTER ENCEPHALITIS; HIPPOCAMPUS; HOSPITAL ADMISSION; HUMAN; IMMUNOFLUORESCENCE; LEUKOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SCHOOL CHILD; SOMNOLENCE; TEMPORAL LOBE; VOMITING;

ADOLESCENT; ADULT; AGED; ANIMALS; ANTIBODIES; CELLS, CULTURED; CHILD; EMBRYO, MAMMALIAN; ENCEPHALITIS, HERPES SIMPLEX; FEMALE; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MICE; MIDDLE AGED; NEURONS; RECEPTORS, N-METHYL-D-ASPARTATE; SYNAPSINS; TRANSFECTION; YOUNG ADULT;

EID: 84871941545     PISSN: 03645134     EISSN: 15318249     Source Type: Journal    
DOI: 10.1002/ana.23689     Document Type: Article

References (22)

1. Steiner I, Kennedy PG, Pachner AR,. The neurotropic herpes viruses: herpes simplex and varicella-zoster. Lancet Neurol 2007; 6: 1015-1028. (Pubitemid 47562323)
2. Whitley R,. Herpes simplex virus. In:, Sheld W, Whitley R, Marra C, eds. Infections of the central nervous system. Philadelphia, PA: Lippincott Williams & Wilkins, 2004: 123-144.
3. Raschilas F, Wolff M, Delatour F, et al. Outcome of and prognostic factors for herpes simplex encephalitis in adult patients: results of a multicenter study. Clin Infect Dis 2002; 35: 254-260. (Pubitemid 34800272)
4. Sellner J, Dvorak F, Zhou Y, et al. Acute and long-term alteration of chemokine mRNA expression after anti-viral and anti-inflammatory treatment in herpes simplex virus encephalitis. Neurosci Lett 2005; 374: 197-202. (Pubitemid 40128295)
5. Kamei S, Sekizawa T, Shiota H, et al. Evaluation of combination therapy using aciclovir and corticosteroid in adult patients with herpes simplex virus encephalitis. J Neurol Neurosurg Psychiatry 2005; 76: 1544-1549. (Pubitemid 41531703)
6. Meyding-Lamade UK, Oberlinner C, Rau PR, et al. Experimental herpes simplex virus encephalitis: a combination therapy of acyclovir and glucocorticoids reduces long-term magnetic resonance imaging abnormalities. J Neurovirol 2003; 9: 118-125. (Pubitemid 36378109)
7. Skoldenberg B, Aurelius E, Hjalmarsson A, et al. Incidence and pathogenesis of clinical relapse after herpes simplex encephalitis in adults. J Neurol 2006; 253: 163-170. (Pubitemid 43255885)
8. De Tiege X, Rozenberg F, Des Portes V, et al. Herpes simplex encephalitis relapses in children: differentiation of two neurologic entities. Neurology 2003; 61: 241-243. (Pubitemid 36875310)
9. Ropper A, Brown R,. Adams and Victor's principles of neurology. 9th ed. New York, NY: McGraw-Hill, 2009.
10. Wandinger KP, Saschenbrecker S, Stoecker W, Dalmau J,. Anti-NMDA-receptor encephalitis: a severe, multistage, treatable disorder presenting with psychosis. J Neuroimmunol 2010; 231: 86-91.
11. Dalmau J, Gleichman AJ, Hughes EG, et al. Anti-NMDA-receptor encephalitis: case series and analysis of the effects of antibodies. Lancet Neurol 2008; 7: 1091-1098.
12. Reiber H, Ungefehr S, Jacobi C,. The intrathecal, polyspecific and oligoclonal immune response in multiple sclerosis. Mult Scler 1998; 4: 111-117. (Pubitemid 28410034)
13. Höltje M, Djalali S, Hofmann F, et al. A 29-amino acid fragment of Clostridium botulinum C3 protein enhances neuronal outgrowth, connectivity, and reinnervation. FASEB J 2009; 23: 1115-1126.
14. Prüss H, Höltje M, Maier N, et al. IgA NMDA receptor antibodies are markers of synaptic immunity in slow cognitive impairment. Neurology 2012; 78: 1743-1753.
15. Prüss H, Dalmau J, Harms L, et al. Retrospective analysis of NMDA receptor antibodies in encephalitis of unknown origin. Neurology 2010; 75: 1735-1739.
16. Manto M, Dalmau J, Didelot A, et al. In vivo effects of antibodies from patients with anti-NMDA receptor encephalitis: further evidence of synaptic glutamatergic dysfunction. Orphanet J Rare Dis 2010; 5: 31.
17. Davies G, Irani SR, Coltart C, et al. Anti-N-methyl-D-aspartate receptor antibodies: a potentially treatable cause of encephalitis in the intensive care unit. Crit Care Med 2010; 38: 679-682.
18. Finke C, Kopp UA, Prüss H, et al. Cognitive deficits following anti-NMDA receptor encephalitis. J Neurol Neurosurg Psychiatry 2011; 83: 195-198.
19. Gable MS, Sheriff H, Dalmau J, et al. The frequency of autoimmune N-methyl-D-aspartate receptor encephalitis surpasses that of individual viral etiologies in young individuals enrolled in the California Encephalitis Project. Clin Infect Dis 2012; 54: 899-904.
20. Dalmau J, Lancaster E, Martinez-Hernandez E, et al. Clinical experience and laboratory investigations in patients with anti-NMDAR encephalitis. Lancet Neurol 2011; 10: 63-74.
21. Gable M, Gavali S, Radner A, et al. Anti-NMDA receptor encephalitis: report of ten cases and comparison with viral encephalitis. Eur J Clin Microbiol Infect Dis 2009; 28: 1421-1429.
22. Granerod J, Ambrose HE, Davies NW, et al. Causes of encephalitis and differences in their clinical presentations in England: a multicentre, population-based prospective study. Lancet Infect Dis 2010; 10: 835-844.