A mutation of the Col2a1 gene (G1170S) alters the transgenic murine phenotype and cartilage matrix homeostasis

Journal of the Formosan Medical Association

Volumn 113, Issue 11, 2014, Pages 803-812

  Yang, Ruei Cheng ^a,b   Chen, Ming Hong ^a,e   Chen, Pei Yu ^d,e   Chen, Ching Yun ^d   Tsai, Shih Feng ^a,f   Cheng, Cheng Kung ^a   Sun, Jui Sheng ^c,e  

^a NATIONAL YANG MING UNIVERSITY   (Taiwan)

^b TAIPEI CITY HOSPITAL   (Taiwan)

^c NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^d NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^f NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

Author keywords

Cartilage; Col2a1; Homeostasis; Phenotype; Transgenic mice

Indexed keywords

COLLAGEN TYPE 2; COLLAGENASE 3; GLYCOSAMINOGLYCAN; INTERLEUKIN 1BETA; NITRIC OXIDE; PROTEINASE; TUMOR NECROSIS FACTOR ALPHA; COL2A1 PROTEIN, MOUSE; CYTOKINE; MMP13 PROTEIN, MOUSE;

ALLELE; ANIMAL EXPERIMENT; ARTICLE; BODY WEIGHT; CARTILAGE CELL; CARTILAGE MATRIX; CELL PROLIFERATION; COL2A1 GENE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE EXPRESSION; GENE MUTATION; MOUSE; MTT ASSAY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POINT MUTATION; UPREGULATION; ANIMAL; CARTILAGE; CELL CULTURE; CYTOLOGY; GENETICS; HOMEOSTASIS; MALE; METABOLISM; MUTATION; PATHOLOGY; TRANSGENIC MOUSE;

ALLELES; ANIMALS; CARTILAGE; CELLS, CULTURED; CHONDROCYTES; COLLAGEN TYPE II; CYTOKINES; GENE EXPRESSION; HOMEOSTASIS; MALE; MATRIX METALLOPROTEINASE 13; MICE; MICE, TRANSGENIC; MUTATION; NITRIC OXIDE; PHENOTYPE;

EID: 84922059171     PISSN: 09296646     EISSN: 18760821     Source Type: Journal    
DOI: 10.1016/j.jfma.2013.09.015     Document Type: Article

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