Novel Nanomonitor ultra-sensitive detection of troponin T

Clinica Chimica Acta

Volumn 442, Issue , 2015, Pages 96-101

  Barrett, Thomas W ^a   Radha Shanmugam, Nandhinee ^b   Selvam, Anjan Panneer ^b   Kazmierczak, Steven C ^c   Prasad, Shalini ^b  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b The University of Texas at Dallas   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Functional sensitivity; Nanotechnology; Point of care; Troponin T

Indexed keywords

BIOLOGICAL MARKER; TROPONIN T;

ANTIGEN BINDING; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN TISSUE; IMPEDANCE; LABORATORY DEVICE; LIMIT OF DETECTION; LINEAR REGRESSION ANALYSIS; NANOMONITOR; POINT OF CARE DEVICE; POINT OF CARE TESTING; PROTEIN ANALYSIS; SENSITIVITY AND SPECIFICITY; BLOOD; BLOOD ANALYSIS; NANOTECHNOLOGY; PROCEDURES;

BLOOD CHEMICAL ANALYSIS; HUMANS; LIMIT OF DETECTION; NANOTECHNOLOGY; TROPONIN T;

EID: 84922032860     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2015.01.013     Document Type: Article

References (25)

1. Thygesen K., Alpert J.S., Jaffe A.S., Simoons M.L., Chaitman B.R., White H.D. Third Universal Definition of Myocardial Infarction. Circulation 2012, 126:2020-2035.
2. Apple F.S. A new season for cardiac troponin assays: it's time to keep a scorecard. Clin Chem 2009, 55:1303-1306.
3. Apple F.S., Collinson P.O., Biomarkers ITFoCAoC Analytical characteristics of high-sensitivity cardiac troponin assays. Clin Chem 2012, 58:54-61.
4. de Lemos J.A., Drazner M.H., Omland T., et al. Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population. JAMA 2010, 304:2503-2512.
5. Giannitsis E., Becker M., Kurz K., Hess G., Zdunek D., Katus H.A. High-sensitivity cardiac troponin T for early prediction of evolving non-ST-segment elevation myocardial infarction in patients with suspected acute coronary syndrome and negative troponin results on admission. Clin Chem 2010, 56:642-650.
6. Giannitsis E., Kurz K., Hallermayer K., Jarausch J., Jaffe A.S., Katus H.A. Analytical validation of a high-sensitivity cardiac troponin T assay. Clin Chem 2010, 56:254-261.
7. Haaf P., Drexler B., Reichlin T., et al. High-sensitivity cardiac troponin in the distinction of acute myocardial infarction from acute cardiac noncoronary artery disease. Circulation 2012, 126:31-40.
8. Bothara M., Venkatraman V., Reddy R.K., Barrett T., Carruthers J., Prasad S. Nanomonitors: electrical immunoassays for protein biomarker profiling. Nanomedicine 2008, 3:423-436.
9. Kunduru V., Bothara M., Grosch J., Sengupta S., Patra P.K., Prasad S. Nanostructured surfaces for enhanced protein detection toward clinical diagnostics. Nanomedicine 2010, 6:642-650.
10. Nagaraj V.J., Aithal S., Eaton S., Bothara M., Wiktor P., Prasad S. NanoMonitor: a miniature electronic biosensor for glycan biomarker detection. Nanomedicine (Lond) 2010, 5:369-378.
11. Reddy R.K., Bothara M.G., Barrett T.W., Carruthers J., Prasad S. Nanomonitors: Protein biosensors for rapid analyte analysis. IEEE Sensors J 2008, 12:720-723.
12. Reddy R.K.K., Prasad S., Barrett T., Carruthers J. Electrical Immunoassays toward Clinical Diagnostics: Identification of Vulnerable Cardiovascular Plaque. J Assoc Lab Autom 2008, 13:33-39.
13. Vattipalli K., Feikert P., Brandigampala S., Prasad S. Study of Nanoporous Membranes with Applications in the Enhanced Detection of Cardiovascular Biomarker Proteins. Nano LIFE 2010, [1:3 & 4].
14. Ellis R.J. Macromolecular crowding: an important but neglected aspect of the intracellular environment. Curr Opin Struct Biol 2001, 11:114-119.
15. Hartl F.U., Hayer-Hartl M. Molecular chaperones in the cytosol: from nascent chain to folded protein. Science 2002, 295:1852-1858.
16. Armbruster D.A., Pry T. Limit of blank, limit of detection and limit of quantitation. Clin Biochem Rev / Aust Assoc Clin Biochem 2008, 29(Suppl. 1):S49-S52.
17. Twerenbold R., Jaffe A., Reichlin T., Reiter M., Mueller C. High-sensitive troponin T measurements: what do we gain and what are the challenges?. Eur Heart J 2012, 33:579-586.
18. Apple F.S., Ler R., Murakami M.M. Determination of 19 cardiac troponin I and T assay 99th percentile values from a common presumably healthy population. Clin Chem 2012, 58:1574-1581.
19. Egstrup M., Schou M., Tuxen C.D., et al. Prediction of outcome by highly sensitive troponin T in outpatients with chronic systolic left ventricular heart failure. Am J Cardiol 2012, 110:552-557.
20. Falkensammer J., Gasteiger S., Stojakovic T., et al. Elevated baseline hs-cTnT levels predict exercise-induced myocardial ischemia in patients with peripheral arterial disease. Clin Chim Acta 2012, 413:1678-1682.
21. Kavsak P.A., Walsh M., Srinathan S., et al. High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: a prospective cohort study. Clin Biochem 2011, 44:1021-1024.
22. Koerbin G., Tate J., Potter J.M., Cavanaugh J., Glasgow N., Hickman P.E. Characterisation of a highly sensitive troponin I assay and its application to a cardio-healthy population. Clin Chem Lab Med 2012, 50:871-878.
23. Sandoval Y., Apple F.S. The global need to define normality: the 99th percentile value of cardiac troponin. Clin Chem 2014, 60:455-462.
24. Korley F.K., Jaffe A.S. Preparing the United States for high-sensitivity cardiac troponin assays. J Am Coll Cardiol 2013, 61:1753-1758.
25. Singh J., Akbar M.S., Adabag S. Discordance of cardiac troponin I assays on the point-of-care i-STAT and Architect assays from Abbott Diagnostics. Clin Chim Acta 2009, 403:259-260.