Usefulness of a fourth generation ELISA assay for the reliable identification of HCV infection in HIV-positive adults from Gabon (Central Africa)

PLoS ONE

Volumn 10, Issue 1, 2015, Pages

  Rouet, François ^a,g   Deleplancque, Luc ^a   Mboumba, Berthold Bivigou ^a   Sica, Jeanne ^b   Mouinga Ondémé, Augustin ^a   Liégeois, Florian ^a,c   Goudeau, Alain ^d,e   Dubois, Frédéric ^d,f   Gaudy Graffin, Catherine ^d,e  

^a CENTRE INTERNATIONAL DE RECHERCHES MÉDICALES DE FRANCEVILLE   (Gabon)

^b Centre de Traitement Ambulatoire (CTA)   (Gabon)

^c INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT   (France)

^d CHU BRETONNEAU   (France)

^e UNIVERSITÉ DE TOURS   (France)

^f IRSA Institut Inter Régional Pour la Santé   (France)

^g Pasteur Institute in Cambodia HIV Hepatitis Unit   (Cambodia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; EFAVIRENZ PLUS LAMIVUDINE PLUS STAVUDINE; EFAVIRENZ PLUS LAMIVUDINE PLUS ZIDOVUDINE; HEPATITIS C ANTIBODY; HEPATITIS C ANTIGEN; NEVIRAPINE; UNCLASSIFIED DRUG; VIRUS RNA;

ADULT; AG-AB ELISA; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; DIAGNOSTIC KIT; DIAGNOSTIC TEST ACCURACY STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FEMALE; G4 HCV ELISA; GABON; HEPATITIS C; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; IMMUNOBLOTTING; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; PREDICTIVE VALUE; RECEIVER OPERATING CHARACTERISTIC; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; SEROPREVALENCE; ADOLESCENT; COMPLICATION; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOLOGY; MIDDLE AGED; PROCEDURES; YOUNG ADULT;

HEPATITIS C VIRUS;

ADOLESCENT; ADULT; CROSS-SECTIONAL STUDIES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FALSE POSITIVE REACTIONS; FEMALE; GABON; HEPATITIS C; HEPATITIS C ANTIBODIES; HEPATITIS C ANTIGENS; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; YOUNG ADULT;

EID: 84922032794     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0116975     Document Type: Article

References (46)

1. El-Serag HB (2012) Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology 142: 1264-1273 e1261. doi: 10.1053/j.gastro.2011.12.061 PMID: 22537432
2. Mohd Hanafiah K, Groeger J, Flaxman AD, Wiersma ST (2013) Global epidemiology of hepatitis C virus infection: new estimates of age-specific antibody to HCV seroprevalence. Hepatology 57: 1333-1342. doi: 10.1002/hep.26141 PMID: 23172780
3. Easterbrook P, Sands A, Harmanci H (2012) Challenges and priorities in the management of HIV/HBV and HIV/HCV coinfection in resource-limited settings. Semin Liver Dis 32: 147-157. doi: 10.1055/s- 0032-1316476 PMID: 22760654
4. Obach D, Deuffic-Burban S, Esmat G, Anwar WA, Dewedar S, et al. (2014) Effectiveness and cost-effectiveness of immediate vs. delayed treatment of HCV-infected patients in a country with limited resources: the case of Egypt. Clin Infect Dis 58: 1064-1071. doi: 10.1093/cid/ciu066 PMID: 24510934
5. Rouet F, Chaix ML, Inwoley A, Msellati P, Viho I, et al. (2004) HBV and HCV prevalence and viraemia in HIV-positive and HIV-negative pregnant women in Abidjan, Cote d'Ivoire: The ANRS 1236 study. J Med Virol 74: 34-40. PMID: 15258966
6. Chasela CS, Wall P, Drobeniuc J, King CC, Teshale E, et al. (2012) Prevalence of hepatitis C virus infection among human immunodeficiency virus-1-infected pregnant women in Malawi: the BAN study. J Clin Virol 54: 318-320. doi: 10.1016/j.jcv.2012.05.003 PMID: 22658797
7. Mullis CE, Laeyendecker O, Reynolds SJ, Ocama P, Quinn J, et al. (2013) High frequency of false-positive hepatitis C virus enzyme-linked immunosorbent assay in Rakai, Uganda. Clin Infect Dis 57: 1747-1750. doi: 10.1093/cid/cit602 PMID: 24051866
8. Alter MJ, Kuhnert WL, Finelli L (2003) Guidelines for laboratory testing and result reporting of antibody to hepatitis C virus. Centers for Disease Control and Prevention. MMWR Recomm Rep 52: 1-13, 15; quiz CE1-4. PMID: 14685139
9. Kamili S, Drobeniuc J, Araujo AC, Hayden TM (2012) Laboratory diagnostics for hepatitis C virus infection. Clin Infect Dis 55 Suppl 1: S43-48. doi: 10.1093/cid/cis368 PMID: 22715213
10. Berger A, Rabenau H, Allwinn R, Doerr HW (2008) Evaluation of the new ARCHITECT anti-HCV screening test under routine laboratory conditions. J Clin Virol 43: 158-161. doi: 10.1016/j.jcv.2008.05. 009 PMID: 18635393
11. Kiely P, Walker K, Parker S, Cheng A (2010) Analysis of sample-to-cutoff ratios on chemiluminescent immunoassays used for blood donor screening highlights the need for serologic confirmatory testing. Transfusion 50: 1344-1351. doi: 10.1111/j.1537-2995.2009.02572.x PMID: 20113456
12. Acar A, Kemahli S, Altunay H, Kosan E, Oncul O, et al. (2010) The significance of repeat testing in Turkish blood donors screened with HBV, HCV and HIV immunoassays and the importance of S/CO ratios in the interpretation of HCV/HIV screening test results and as a determinant for further confirmatory testing. Transfus Med 20: 152-159. doi: 10.1111/j.1365-3148.2009.00987.x PMID: 20059750
13. Wu S, Liu Y, Cheng L, Yin B, Peng J, et al. (2011) Clinical evaluation of the signal-to-cutoff ratios of hepatitis C virus antibody screening tests used in China. J Med Virol 83: 1930-1937. doi: 10.1002/jmv. 22168 PMID: 21915868
14. Moretti M, Pieretti B, Masucci A, Sisti D, Rocchi M, et al. (2012) Role of signal-to-cutoff ratios in hepatitis C virus antibody detection. Clin Vaccine Immunol 19: 1329-1331. doi: 10.1128/CVI.00175-12 PMID: 22695164
15. Scheiblauer H, El-Nageh M, Nick S, Fields H, Prince A, et al. (2006) Evaluation of the performance of 44 assays used in countries with limited resources for the detection of antibodies to hepatitis C virus. Transfusion 46: 708-718. PMID: 16686838
16. Firdaus R, Saha K, Sadhukhan PC (2013) Rapid immunoassay alone is insufficient for the detection of hepatitis C virus infection among high-risk population. J Viral Hepat 20: 290-293. doi: 10.1111/jvh. 12002 PMID: 23490374
17. Tagny CT, Mbanya D, Murphy EL, Lefrere JJ, Laperche S (2014) Screening for hepatitis C virus infection in a high prevalence country by an antigen/antibody combination assay versus a rapid test. J Virol Methods 199: 119-123. doi: 10.1016/j.jviromet.2014.01.002 PMID: 24487098
18. El Sharkawi FZ, Chudy M, Hanschmann KM, Kress J, Nubling CM (2008) Consistency of quantitation of HCV genotype 4 from egypt across three HCV-RNA amplification assays. J Med Virol 80: 2086-2091. doi: 10.1002/jmv.21325 PMID: 19040283
19. Agha S, Tanaka Y, Saudy N, Kurbanov F, Abo-Zeid M, et al. (2004) Reliability of hepatitis C virus core antigen assay for detection of viremia in HCV genotypes 1, 2, 3, and 4 infected blood donors: a collaborative study between Japan, Egypt, and Uzbekistan. J Med Virol 73: 216-222. PMID: 15122795
20. Martel-Laferriere V, Bichoupan K, Dieterich DT (2014) Hepatitis C Direct-acting Antiviral Agents: Changing the Paradigm of Hepatitis C Treatment in HIV-infected Patients. J Clin Gastroenterol 48: 106-112. doi: 10.1097/MCG.0000000000000010 PMID: 24172182
21. Anonymous (2013) Testing for HCV infection: an update of guidance for clinicians and laboratorians. MMWR Morb Mortal Wkly Rep 62: 362-365. PMID: 23657112
22. Gaudy C, Thevenas C, Tichet J, Mariotte N, Goudeau A, et al. (2005) Usefulness of the hepatitis C virus core antigen assay for screening of a population undergoing routine medical checkup. J Clin Microbiol 43: 1722-1726. PMID: 15814991
23. Proust B, Dubois F, Bacq Y, Le Pogam S, Rogez S, et al. (2000) Two successive hepatitis C virus infections in an intravenous drug user. J Clin Microbiol 38: 3125-3127. PMID: 10921996
24. McGovern BH, Birch CE, Bowen MJ, Reyor LL, Nagami EH, et al. (2009) Improving the diagnosis of acute hepatitis C virus infection with expanded viral load criteria. Clin Infect Dis 49: 1051-1060. doi: 10.1086/605561 PMID: 19725787
25. Gaudy-Graffin C, Lesage G, Kousignian I, Laperche S, Girault A, et al. (2010) Use of an anti-hepatitis C virus (HCV) IgG avidity assay to identify recent HCV infection. J Clin Microbiol 48: 3281-3287. doi: 1128/JCM.00303-10 PMID: 20610669
26. Liegeois F, Vella C, Eymard-Duvernay S, Sica J, Makosso L, et al. (2012) Virological failure rates and HIV-1 drug resistance patterns in patients on first-line antiretroviral treatment in semirural and rural Gabon. J Int AIDS Soc 15: 17985. doi: 10.7448/IAS.15.2.17985 PMID: 23199801
27. Schnuriger A, Dominguez S, Valantin MA, Tubiana R, Duvivier C, et al. (2006) Early detection of hepatitis C virus infection by use of a new combined antigen-antibody detection assay: Potential use for highrisk individuals. J Clin Microbiol 44: 1561-1563. PMID: 16597894
28. Bukh J, Purcell RH, Miller RH (1992) Importance of primer selection for the detection of hepatitis C virus RNA with the polymerase chain reaction assay. Proc Natl Acad Sci U S A 89: 187-191. PMID: 1309604
29. Njouom R, Caron M, Besson G, Ndong-Atome GR, Makuwa M, et al. (2012) Phylogeography, risk factors and genetic history of hepatitis C virus in Gabon, Central Africa. PLoS One 7: e42002. doi: 1371/journal.pone.0042002 PMID: 22870274
30. Lin S, Arcangel P, Medina-Selby A, Coit D, Ng P, et al. (2005) Design of novel conformational and genotype- specific antigens for improving sensitivity of immunoassays for hepatitis C virus-specific antibodies. J Clin Microbiol 43: 3917-3924. PMID: 16081931
31. Medici MC, Furlini G, Rodella A, Fuertes A, Monachetti A, et al. (2011) Hepatitis C virus core antigen: analytical performances, correlation with viremia and potential applications of a quantitative, automated immunoassay. J Clin Virol 51: 264-269. doi: 10.1016/j.jcv.2011.05.003 PMID: 21621454
32. Saez-Cirion A, Bacchus C, Hocqueloux L, Avettand-Fenoel V, Girault I, et al. (2013) Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog 9: e1003211. doi: 10.1371/journal.ppat.1003211 PMID: 23516360
33. Dubois F, Barin F, Goudeau A (1998) Anti-HCV serology for screening, diagnosis and surveillance of hepatitis C: role of the immunoblot. Ann Biol Clin (Paris) 56: 417-426. PMID: 9754277
34. Maniez-Montreuil M, Dubois F (2000) Interpretation of hepatitis C virus serology: immunoblot and genome amplification. Transfus Clin Biol 7 Suppl 1: 25s-30s. PMID: 10919220
35. Hanley JA (1996) The use of the 'binormal' model for parametric ROC analysis of quantitative diagnostic tests. Stat Med 15: 1575-1585. PMID: 8855483
36. Vecchio TJ (1966) Predictive value of a single diagnostic test in unselected populations. N Engl J Med 274: 1171-1173. PMID: 5934954
37. Caudai C, Padula MG, Bastianoni I, Valensin PE, Shyamala V, et al. (1998) Antibody testing and RTPCR results in hepatitis C virus (HCV) infection: HCV-RNA detection in PBMC of plasma viremia-negative HCV-seropositive persons. Infection 26: 151-154. PMID: 9646105
38. Kenny-Walsh E (1999) Clinical outcomes after hepatitis C infection from contaminated anti-D immune globulin. Irish Hepatology Research Group. N Engl J Med 340: 1228-1233. PMID: 10210705
39. Messick K, Sanders JC, Goedert JJ, Eyster ME (2001) Hepatitis C viral clearance and antibody reactivity patterns in persons with haemophilia and other congenital bleeding disorders. Haemophilia 7: 568-574. PMID: 11851755
40. Schulze Zur Wiesch J, Ciuffreda D, Lewis-Ximenez L, Kasprowicz V, Nolan BE, et al. (2012) Broadly directed virus-specific CD4+ T cell responses are primed during acute hepatitis C infection, but rapidly disappear from human blood with viral persistence. J Exp Med 209: 61-75. doi: 10.1084/jem. 20100388 PMID: 22213804
41. Castelain S, Schnuriger A, Francois C, Nguyen-Khac E, Fournier C, et al. (2008) Low levels of hepatitis C virus (HCV) neutralizing antibodies in patients coinfected with HCV and human immunodeficiency virus. J Infect Dis 198: 332-335. doi: 10.1086/589777 PMID: 18558868
42. Perz JF, Grytdal S, Beck S, Fireteanu AM, Poissant T, et al. (2013) Case-control study of hepatitis B and hepatitis C in older adults: Do healthcare exposures contribute to burden of new infections? Hepatology 57: 917-924. doi: 10.1002/hep.25688 PMID: 22383058
43. Alipour A, Rezaianzadeh A, Hasanzadeh J, Rajaeefard A, Davarpanah MA (2013) Sexual Transmission of Hepatitis C Virus Between HIV Infected Subjects and Their Main Heterosexual Partners. Hepat Mon 13: e13593. doi: 10.5812/hepatmon.13593 PMID: 24348647
44. Descamps V, Op de Beeck A, Plassart C, Brochot E, Francois C, et al. (2012) Strong correlation between liver and serum levels of hepatitis C virus core antigen and RNA in chronically infected patients. J Clin Microbiol 50: 465-468. doi: 10.1128/JCM.06503-11 PMID: 22162563
45. Dawson GJ (2012) The potential role of HCV core antigen testing in diagnosing HCV infection. Antivir Ther 17: 1431-1435. doi: 10.3851/IMP2463 PMID: 23322590
46. Ottiger C, Gygli N, Huber AR (2013) Detection limit of architect hepatitis C core antigen assay in correlation with HCV RNA, and renewed confirmation algorithm for reactive anti-HCV samples. J Clin Virol 58: 535-540. doi: 10.1016/j.jcv.2013.08.028 PMID: 24041472