The microRNA-367 inhibits the invasion and metastasis of gastric cancer by directly repressing Rab23

Genetic Testing and Molecular Biomarkers

Volumn 19, Issue 2, 2015, Pages 69-74

  Bin, Zhang ^a   Dedong, He ^a   Xiangjie, Fang ^a   Hongwei, Xu ^a   Qinghui, Yang ^b  

^a First Hospital Affiliated to the Xinxiang Medical University   (China)

^b XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 367; RAB PROTEIN; RAB23 PROTEIN; UNCLASSIFIED DRUG; 3' UNTRANSLATED REGION; MIRN367 MICRORNA, HUMAN; RAB23 PROTEIN, HUMAN; RECOMBINANT DNA; RNA; TUMOR PROTEIN;

ADULT; ARTICLE; BIOINFORMATICS; CANCER CELL; CELL DIFFERENTIATION; CELL INVASION; CELL MIGRATION; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; MALE; METASTASIS; REAL TIME POLYMERASE CHAIN REACTION; REPORTER GENE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STOMACH CANCER; TUMOR INVASION; 3' UNTRANSLATED REGION; AGED; BIOSYNTHESIS; CARCINOMA; CELL MOTION; CHEMISTRY; DOWN REGULATION; GENE EXPRESSION REGULATION; GENETICS; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; STOMACH; STOMACH TUMOR; TUMOR CELL LINE;

3' UNTRANSLATED REGIONS; AGED; CARCINOMA; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL MOVEMENT; DNA, RECOMBINANT; DOWN-REGULATION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MALE; MICRORNAS; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; RAB GTP-BINDING PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; RNA, NEOPLASM; STOMACH; STOMACH NEOPLASMS;

EID: 84922023900     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2014.0210     Document Type: Article

References (22)

1. Bartel DP (2004) MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 116:281-297.
2. Brenner B, Hoshen MB, Purim O, et al. (2011) MicroRNAs as a potential prognostic factor in gastric cancer. World J Gastroenterol 17:3976-3985.
3. Campayo M, Navarro A, Vinolas N, et al. (2013) Low miR-145 and highmiR-367 are associated with unfavourable prognosis in resected nonsmall cell lung cancer. Eur Respir J 41:1172-1178.
4. Chae YS, Kim JG, Kang BW, et al. (2013) Functional polymorphism in the MicroRNA-367 binding site as a prognostic factor for colonic cancer. Anticancer Res 33:513-519.
5. Costa FF, Bischof JM, Vanin EF, et al. (2011) Identification of microRNAs as potential prognostic markers in ependymoma. PLoS One 6:e25114.
6. Farh KK, Grimson A, Jan C, et al. (2005) The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science 310:1817-1821.
7. Gao P, Xing AY, Zhou GY, et al. (2013) The molecular mechanism of microRNA-145 to suppress invasion-metastasis cascade in gastric cancer. Oncogene 32:491-501.
8. Guo A, Wang T, Ng EL, et al. (2006) Open brain gene product Rab23: expression pattern in the adult mouse brain and functional characterization. J Neurosci Res 83:1118-1127.
9. Hou Q, Wu YH, Grabsch H, et al. (2008) Integrative genomics identifies RAB23 as an invasion mediator gene in diffuse-type gastric cancer. Cancer Res 68:4623-4630.
10. Jemal A, Siegel R, Xu J, Ward E (2010) Cancer statistics, 2010. CA Cancer J Clin 60:277-300.
11. Kim JG (2013) Molecular targeted therapy for advanced gastric cancer. Korean J Intern Med 28:149-155.
12. Liu YJ, Wang Q, Li W, et al. (2007) Rab23 is a potential biological target for treating hepatocellular carcinoma. World J Gastroenterol 13:1010-1017.
13. Lo SS, Hung PS, Chen JH, et al. (2012) Overexpression of miR-370 and downregulation of its novel target TGFbeta-RII contribute to the progression of gastric carcinoma. Oncogene 31:226-237.
14. Pan HW, Li SC, Tsai KW (2013) MicroRNA dysregulation in gastric cancer. Curr Pharm Des 19:1273-1284.
15. Smith AC, Heo WD, Braun V, et al. (2007) A network of Rab GTPases controls phagosome maturation and is modulated by Salmonella enterica serovar Typhimurium. J Cell Biol 176: 263-268.
16. Tamura G, Yin J, Wang S, et al. (2000) E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas. J Natl Cancer Inst 92:569-573.
17. Wang J, Wang Q, Liu H, et al. (2010) MicroRNA expression and its implication for the diagnosis and therapeutic strategies of gastric cancer. Cancer Lett 297:137-143.
18. Wang J, Zhang J, Wu J, et al. (2012) MicroRNA-610 inhibits the migration and invasion of gastric cancer cells by suppressing the expression of vasodilator-stimulated phosphoprotein. Eur J Cancer 48:1904-1913.
19. Wu WK, Lee CW, Cho CH, et al. (2010) MicroRNA dysregulation in gastric cancer: a new player enters the game. Oncogene 29:5761-5771.
20. Xu Y, Zhao F, Wang Z, et al. (2012) MicroRNA-335 acts as a metastasis suppressor in gastric cancer by targeting Bcl-w and specificity protein 1. Oncogene 31:1398-1407.
21. Zhang L, Liu Y, Song F, et al. (2011) Functional SNP in the microRNA-367 binding site in the 3UTR of the calciumchannel ryanodine receptor gene 3 (RYR3) affects breast cancer risk and calcification. Proc Natl Acad Sci U S A 108:13653-13658.
22. Zheng B, Liang L, Wang C, et al. (2011) MicroRNA-148a suppresses tumor cell invasion and metastasis by downregulating ROCK1 in gastric cancer. Clin Cancer Res 17:7574-7583.