Characterization of pro-invasive mechanisms and N-terminal cleavage of ANXA1 in melanoma

Archives of Dermatological Research

Volumn 306, Issue 10, 2014, Pages 903-914

  Boudhraa, Z ^a   Merle, C ^b   Mazzocut, D ^c   Chezal, J M ^a   Chambon, C ^d   Miot Noirault, E ^a   Theisen, M ^b   Bouchon, B ^a   Degoul, F ^a  

^a INSERM   (France)

^b Proteodynamics   (France)

^c INSTITUT DE BIOLOGIE ET CHIMIE DES PROTÉINES   (France)

^d INRA and University of Auvergne   (France)

Author keywords

Annexin A1; Annexin A1 cleavage; Annexin A1 externalization; FPRs; Melanoma invasion

Indexed keywords

FORMYLPEPTIDE RECEPTOR; GELATINASE A; LIPOCORTIN 1; LYSINE; SERINE; SERINE PROTEINASE; STAT3 PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; MMP2 PROTEIN, HUMAN; PEPTIDE FRAGMENT; STAT3 PROTEIN, HUMAN;

A375 CELL LINE; ANIMAL CELL; ARTICLE; CELL SURFACE; CONTROLLED STUDY; HUMAN; HUMAN CELL; MALE; MELANOMA; MELANOMA CELL LINE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEOMICS; SIGNAL TRANSDUCTION; ANIMAL; AUTOCRINE EFFECT; CELL MEMBRANE; ENZYMOLOGY; METABOLISM; NUDE MOUSE; PARACRINE SIGNALING; PATHOLOGY; PROTEIN TERTIARY STRUCTURE; SKIN TUMOR; TUMOR CELL LINE; TUMOR INVASION;

ANIMALS; ANNEXIN A1; AUTOCRINE COMMUNICATION; CELL LINE, TUMOR; CELL MEMBRANE; HUMANS; MALE; MATRIX METALLOPROTEINASE 2; MELANOMA; MICE, NUDE; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASM INVASIVENESS; PARACRINE COMMUNICATION; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, FORMYL PEPTIDE; SERINE PROTEASES; SIGNAL TRANSDUCTION; SKIN NEOPLASMS; STAT3 TRANSCRIPTION FACTOR;

EID: 84922002692     PISSN: 03403696     EISSN: 1432069X     Source Type: Journal    
DOI: 10.1007/s00403-014-1517-z     Document Type: Article

References (42)

1. Aalberts M, van Dissel-Emiliani FM, van Adrichem NP, van Wijnen M, Wauben MH, Stout TA, Stoorvogel W (2012) Identification of distinct populations of prostasomes that differentially express prostate stem cell antigen, annexin A1, and GLIPR2 in humans. Biol Reprod 86:82
2. Bamford S, Dawson E, Forbes S, Clements J, Pettett R, Dogan A, Flanagan A, Teague J, Futreal PA, Stratton MR, Wooster R (2004) The COSMIC (Catalogue of Somatic Mutations in Cancer) database and website. Br J Cancer 91:355–358
3. Bist P, Leow SC, Phua QH, Shu S, Zhuang Q, Loh WT, Nguyen TH, Zhou JB, Hooi SC, Lim LH (2011) Annexin-1 interacts with NEMO and RIP1 to constitutively activate IKK complex and NF-kappaB: implication in breast cancer metastasis. Oncogene 30:3174–3185
4. Bizzarro V, Belvedere R, Dal Piaz F, Parente L, Petrella A (2012) Annexin A1 induces skeletal muscle cell migration acting through formyl peptide receptors. PLoS One 7:e48246
5. Blume KE, Soeroes S, Keppeler H, Stevanovic S, Kretschmer D, Rautenberg M, Wesselborg S, Lauber K (2012) Cleavage of annexin A1 by ADAM10 during secondary necrosis generates a monocytic “find-me” signal. J Immunol 188:135–145
6. Blume KE, Soeroes S, Waibel M, Keppeler H, Wesselborg S, Herrmann M, Schulze-Osthoff K, Lauber K (2009) Cell surface externalization of annexin A1 as a failsafe mechanism preventing inflammatory responses during secondary necrosis. J Immunol 183:8138–8147
7. Bonnet M, Mishellany F, Papon J, Cayre A, Penault-Llorca F, Madelmont JC, Miot-Noirault E, Chezal JM, Moins N (2010) Anti-melanoma efficacy of internal radionuclide therapy in relation to melanin target distribution. Pigment Cell Melanoma Res 23:e1–11
8. Boudhraa Z, Rondepierre F, Ouchchane L, Kintossou R, Trzeciakiewicz A, Franck F, Kanitakis J, Labeille B, Joubert-Zakeyh J, Bouchon B, Perrot JL, Mansard S, Papon J, Dechelotte P, Chezal JM, Miot-Noirault E, Bonnet M, D’Incan M, Degoul F (2014) Annexin A1 in primary tumors promotes melanoma dissemination. Clin Exp Metastasis. doi:10.1007/s10585-014-9665-2
9. Cheng TY, Wu MS, Lin JT, Lin MT, Shun CT, Huang HY, Hua KT, Kuo ML (2012) Annexin A1 is associated with gastric cancer survival and promotes gastric cancer cell invasiveness through the formyl peptide receptor/extracellular signal-regulated kinase/integrin beta-1-binding protein 1 pathway. Cancer 118:5757–5767
10. Cooray SN, Gobbetti T, Montero-Melendez T, McArthur S, Thompson D, Clark AJ, Flower RJ, Perretti M (2013) Ligand-specific conformational change of the G-protein-coupled receptor ALX/FPR2 determines proresolving functional responses. Proc Natl Acad Sci USA 110:18232–18237
11. Darnell JE Jr (1997) STATs and gene regulation. Science 277:1630–1635
12. Forbes S, Clements J, Dawson E, Bamford S, Webb T, Dogan A, Flanagan A, Teague J, Wooster R, Futreal PA, Stratton MR (2006) Cosmic 2005. Br J Cancer 94:318–322
13. Fu H, Karlsson J, Bylund J, Movitz C, Karlsson A, Dahlgren C (2006) Ligand recognition and activation of formyl peptide receptors in neutrophils. J Leukoc Biol 79:247–256
14. Geary LA, Nash KA, Adisetiyo H, Liang M, Liao CP, Jeong JH, Zandi E, Roy-Burman P (2014) CAF-secreted annexin a1 induces prostate cancer cells to gain stem cell-like features. Mol Cancer Res 12:607–621
15. 2+ signalling to membrane dynamics. Nat Rev Mol Cell Biol 6:449–461
16. Gerke V, Moss SE (2002) Annexins: from structure to function. Physiol Rev 82:331–371
17. Guo C, Liu S, Sun MZ (2013) Potential role of Anxa1 in cancer. Future Oncol 9:1773–1793
18. Kang H, Ko J, Jang SW (2012) The role of annexin A1 in expression of matrix metalloproteinase-9 and invasion of breast cancer cells. Biochem Biophys Res Commun 423:188–194
19. Khau T, Langenbach SY, Schuliga M, Harris T, Johnstone CN, Anderson RL, Stewart AG (2011) Annexin-1 signals mitogen-stimulated breast tumor cell proliferation by activation of the formyl peptide receptors (FPRs) 1 and 2. FASEB J 25:483–496
20. Kim SD, Kim JM, Jo SH, Lee HY, Lee SY, Shim JW, Seo SK, Yun J, Bae YS (2009) Functional expression of formyl peptide receptor family in human NK cells. J Immunol 183:5511–5517
21. Li Y, Ye D (2013) Molecular biology for formyl peptide receptors in human diseases. J Mol Med 91:781–789
22. Liu M, Zhao J, Chen K, Bian X, Wang C, Shi Y, Wang JM (2012) G protein-coupled receptor FPR1 as a pharmacologic target in inflammation and human glioblastoma. Int Immunopharmacol 14:283–288
23. Matsudaira P (1987) Sequence from picomole quantities of proteins electroblotted onto polyvinylidene difluoride membranes. J Biol Chem 262:10035–10038
24. Movitz C, Brive L, Hellstrand K, Rabiet MJ, Dahlgren C (2010) The annexin I sequence gln(9)-ala(10)-trp(11)-phe(12) is a core structure for interaction with the formyl peptide receptor 1. J Biol Chem 285:14338–14345
25. Mussunoor S, Murray GI (2008) The role of annexins in tumour development and progression. J Pathol 216:131–140. doi:10.1002/path.2400
26. Peinado H, Aleckovic M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, Hergueta-Redondo M, Williams C, Garcia-Santos G, Ghajar C, Nitadori-Hoshino A, Hoffman C, Badal K, Garcia BA, Callahan MK, Yuan J, Martins VR, Skog J, Kaplan RN, Brady MS, Wolchok JD, Chapman PB, Kang Y, Bromberg J, Lyden D (2012) Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med 18:883–891
27. Perretti M, D’Acquisto F (2009) Annexin A1 and glucocorticoids as effectors of the resolution of inflammation. Nat Rev Immunol 9:62–70
28. Perretti M, Solito E (2004) Annexin 1 and neutrophil apoptosis. Biochem Soc Trans 32:507–510
29. Pupjalis D, Goetsch J, Kottas DJ, Gerke V, Rescher U (2011) Annexin A1 released from apoptotic cells acts through formyl peptide receptors to dampen inflammatory monocyte activation via JAK/STAT/SOCS signalling. EMBO Mol Med 3:102–114
30. Rescher U, Goebeler V, Wilbers A, Gerke V (2006) Proteolytic cleavage of annexin 1 by human leukocyte elastase. Biochim Biophys Acta 1763:1320–1324
31. Rondepierre F, Bouchon B, Papon J, Bonnet-Duquennoy M, Kintossou R, Moins N, Maublant J, Madelmont JC, D’Incan M, Degoul F (2009) Proteomic studies of B16 lines: involvement of annexin A1 in melanoma dissemination. Biochim Biophys Acta 1794:61–69
32. Rosengarth A, Gerke V, Luecke H (2001) X-ray structure of full-length annexin 1 and implications for membrane aggregation. J Mol Biol 306:489–498
33. Rosengarth A, Luecke H (2003) A calcium-driven conformational switch of the N-terminal and core domains of annexin A1. J Mol Biol 326:1317–1325
34. Sakaguchi M, Murata H, Sonegawa H, Sakaguchi Y, Futami J, Kitazoe M, Yamada H, Huh NH (2007) Truncation of annexin A1 is a regulatory lever for linking epidermal growth factor signaling with cytosolic phospholipase A2 in normal and malignant squamous epithelial cells. J Biol Chem 282:35679–35686
35. Sakaguchi M, Oka M, Iwasaki T, Fukami Y, Nishigori C (2012) Role and regulation of STAT3 phosphorylation at Ser727 in melanocytes and melanoma cells. J Invest Dermatol 132:1877–1885
36. Sakwe AM, Koumangoye R, Guillory B, Ochieng J (2011) Annexin A6 contributes to the invasiveness of breast carcinoma cells by influencing the organization and localization of functional focal adhesions. Exp Cell Res 317:823–837
37. Scannell M, Flanagan MB, deStefani A, Wynne KJ, Cagney G, Godson C, Maderna P (2007) Annexin-1 and peptide derivatives are released by apoptotic cells and stimulate phagocytosis of apoptotic neutrophils by macrophages. J Immunol 178:4595–4605
38. Tsai WH, Chien HY, Shih CH, Lai SL, Li IT, Hsu SC, Kou YR, Hsu HC (2012) Annexin A1 mediates the anti-inflammatory effects during the granulocytic differentiation process in all-trans retinoic acid-treated acute promyelocytic leukemic cells. J Cell Physiol 227:3661–3669
39. Vong L, D’Acquisto F, Pederzoli-Ribeil M, Lavagno L, Flower RJ, Witko-Sarsat V, Perretti M (2007) Annexin 1 cleavage in activated neutrophils: a pivotal role for proteinase 3. J Biol Chem 282:29998–30004
40. Wang L, Ling Y, Chen Y, Li CL, Feng F, You QD, Lu N, Guo QL (2010) Flavonoid baicalein suppresses adhesion, migration and invasion of MDA-MB-231 human breast cancer cells. Cancer Lett 297:42–48
41. Wen Z, Zhong Z, Darnell JE Jr (1995) Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82:241–250
42. Xie TX, Wei D, Liu M, Gao AC, Ali-Osman F, Sawaya R, Huang S (2004) Stat3 activation regulates the expression of matrix metalloproteinase-2 and tumor invasion and metastasis. Oncogene 23:3550–3560