메뉴 건너뛰기




Volumn 88, Issue 17, 2014, Pages 9693-9703

Intranasal adenovirus-vectored vaccine for induction of long-lasting humoral immunity-mediated broad protection against influenza in mice

Author keywords

[No Author keywords available]

Indexed keywords

DRUG CARRIER; HEMAGGLUTININ, AVIAN INFLUENZA A VIRUS; INFLUENZA VACCINE; INFLUENZA VIRUS HEMAGGLUTININ; M1 PROTEIN, INFLUENZA A VIRUS; MATRIX PROTEIN; RECOMBINANT VACCINE; VIRUS ANTIBODY;

EID: 84921983245     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00823-14     Document Type: Article
Times cited : (29)

References (59)
  • 2
    • 0022588771 scopus 로고
    • Serum and nasal wash antibodies associated with resistance to experimental challenge with influenza A wild-type virus
    • Clements ML, Betts RF, Tierney EL, Murphy BR. 1986. Serum and nasal wash antibodies associated with resistance to experimental challenge with influenza A wild-type virus. J. Clin. Microbiol. 24:157-160.
    • (1986) J. Clin. Microbiol , vol.24 , pp. 157-160
    • Clements, M.L.1    Betts, R.F.2    Tierney, E.L.3    Murphy, B.R.4
  • 3
    • 0016417504 scopus 로고
    • Assessment of immunity to influenza using artificial challenge of normal volunteers with influenza virus
    • Couch RB. 1975. Assessment of immunity to influenza using artificial challenge of normal volunteers with influenza virus. Dev. Biol. Stand. 28:295-306.
    • (1975) Dev. Biol. Stand , vol.28 , pp. 295-306
    • Couch, R.B.1
  • 4
    • 0015452705 scopus 로고
    • The role of serum haemagglutination-inhibiting antibody in protection against challenge infection with influenza A2 and B viruses
    • Hobson D, Curry RL, Beare AS, Ward-Gardner A. 1972. The role of serum haemagglutination-inhibiting antibody in protection against challenge infection with influenza A2 and B viruses. J. Hyg. (Lond.) 70:767-777. http://dx.doi.org/10.1017/S0022172400022610.
    • (1972) J. Hyg. (Lond.) , vol.70 , pp. 767-777
    • Hobson, D.1    Curry, R.L.2    Beare, A.S.3    Ward-Gardner, A.4
  • 6
    • 2442671345 scopus 로고    scopus 로고
    • Monoclonal antibodies recognizing EVETPIRN epitope of influenza A virus M2 protein could protect mice from lethal influenza A virus challenge
    • Liu W, Zou P, Chen Y-H. 2004. Monoclonal antibodies recognizing EVETPIRN epitope of influenza A virus M2 protein could protect mice from lethal influenza A virus challenge. Immunol. Lett. 93:131-136. http://dx.doi.org/10.1016/j.imlet.2004.03.003.
    • (2004) Immunol. Lett , vol.93 , pp. 131-136
    • Liu, W.1    Zou, P.2    Chen, Y.-H.3
  • 7
    • 0033079822 scopus 로고    scopus 로고
    • Treatment of influenza virus-infected SCID mice with nonneutralizing antibodies specific for the transmembrane proteins matrix 2 and neuraminidase reduces the pulmonary virus titer but fails to clear the infection
    • Mozdzanowska K, Maiese K, Furchner M, Gerhard W. 1999. Treatment of influenza virus-infected SCID mice with nonneutralizing antibodies specific for the transmembrane proteins matrix 2 and neuraminidase reduces the pulmonary virus titer but fails to clear the infection. Virology 254:138-146. http://dx.doi.org/10.1006/viro.1998.9534.
    • (1999) Virology , vol.254 , pp. 138-146
    • Mozdzanowska, K.1    Maiese, K.2    Furchner, M.3    Gerhard, W.4
  • 8
    • 0032874490 scopus 로고    scopus 로고
    • A universal influenza A vaccine based on the extracellular domain of theM2protein
    • Neirynck S, Deroo T, Saelens X, Vanlandschoot P, Jou WM, Fiers W. 1999. A universal influenza A vaccine based on the extracellular domain of theM2protein. Nat. Med. 5:1157-1163. http://dx.doi.org/10.1038/13484.
    • (1999) Nat. Med , vol.5 , pp. 1157-1163
    • Neirynck, S.1    Deroo, T.2    Saelens, X.3    Vanlandschoot, P.4    Jou, W.M.5    Fiers, W.6
  • 9
    • 0025241767 scopus 로고
    • Passively transferred monoclonal antibody to the M2 protein inhibits influenza A virus replication in mice
    • Treanor JJ, Tierney EL, Zebedee SL, Lamb RA, Murphy BR. 1990. Passively transferred monoclonal antibody to the M2 protein inhibits influenza A virus replication in mice. J. Virol. 64:1375-1377.
    • (1990) J. Virol , vol.64 , pp. 1375-1377
    • Treanor, J.J.1    Tierney, E.L.2    Zebedee, S.L.3    Lamb, R.A.4    Murphy, B.R.5
  • 10
    • 0033522471 scopus 로고    scopus 로고
    • Modified M2 proteins produce heterotypic immunity against influenza A virus
    • Frace AM, Klimov AI, Rowe T, Black RA, Katz JM. 1999. Modified M2 proteins produce heterotypic immunity against influenza A virus. Vaccine 17:2237-2244. http://dx.doi.org/10.1016/S0264-410X(99)00005-5.
    • (1999) Vaccine , vol.17 , pp. 2237-2244
    • Frace, A.M.1    Klimov, A.I.2    Rowe, T.3    Black, R.A.4    Katz, J.M.5
  • 11
    • 0038402706 scopus 로고    scopus 로고
    • Induction of influenza type A virus-specific resistance by immunization of mice with a synthetic multiple antigenic peptide vaccine that contains ectodomains of matrix protein 2
    • Mozdzanowska K, Feng J, Eid M, Kragol G, Cudic M, Otvos L, Jr, Gerhard W. 2003. Induction of influenza type A virus-specific resistance by immunization of mice with a synthetic multiple antigenic peptide vaccine that contains ectodomains of matrix protein 2. Vaccine 21:2616-2626. http://dx.doi.org/10.1016/S0264-410X(03)00040-9.
    • (2003) Vaccine , vol.21 , pp. 2616-2626
    • Mozdzanowska, K.1    Feng, J.2    Eid, M.3    Kragol, G.4    Cudic, M.5    Otvos, L.6    Gerhard, W.7
  • 13
    • 0028821987 scopus 로고
    • Protection of mice against influenza A virus challenge by vaccination with baculovirus-expressedM2protein
    • Slepushkin VA, Katz JM, Black RA, Gamble WC, Rota PA, Cox NJ. 1995. Protection of mice against influenza A virus challenge by vaccination with baculovirus-expressedM2protein. Vaccine 13:1399-1402. http://dx.doi.org/10.1016/0264-410X(95)92777-Y.
    • (1995) Vaccine , vol.13 , pp. 1399-1402
    • Slepushkin, V.A.1    Katz, J.M.2    Black, R.A.3    Gamble, W.C.4    Rota, P.A.5    Cox, N.J.6
  • 14
    • 0032874490 scopus 로고    scopus 로고
    • A universal influenza A vaccine based on the extracellular domain of the M2 protein
    • Neirynck S, Deroo T, Saelens X, Vanlandschoot P, Jou WM, Fiers W. 1999. A universal influenza A vaccine based on the extracellular domain of the M2 protein. Nat. Med. 5:1157-1163. http://dx.doi.org/10.1038/13484.
    • (1999) Nat. Med , vol.5 , pp. 1157-1163
    • Neirynck, S.1    Deroo, T.2    Saelens, X.3    Vanlandschoot, P.4    Jou, W.M.5    Fiers, W.6
  • 19
    • 0020172113 scopus 로고
    • Evolution of influenza A and B viruses: conservation of structural features in the hemagglutinin genes
    • Krystal M, Elliott RM, Benz EW, Jr, Young JF, Palese P. 1982. Evolution of influenza A and B viruses: conservation of structural features in the hemagglutinin genes. P. Natl. Acad. Sci. U. S. A. 79:4800-4804. http://dx.doi.org/10.1073/pnas.79.15.4800.
    • (1982) P. Natl. Acad. Sci. U. S. A , vol.79 , pp. 4800-4804
    • Krystal, M.1    Elliott, R.M.2    Benz, E.W.3    Young, J.F.4    Palese, P.5
  • 20
    • 0027471177 scopus 로고
    • A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains
    • Okuno Y, Isegawa Y, Sasao F, Ueda S. 1993. A common neutralizing epitope conserved between the hemagglutinins of influenza A virus H1 and H2 strains. J. Virol. 67:2552-2558.
    • (1993) J. Virol , vol.67 , pp. 2552-2558
    • Okuno, Y.1    Isegawa, Y.2    Sasao, F.3    Ueda, S.4
  • 25
    • 84878611784 scopus 로고    scopus 로고
    • Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies
    • Krammer F, Pica N, Hai R, Margine I, Palese P. 2013. Chimeric hemagglutinin influenza virus vaccine constructs elicit broadly protective stalk-specific antibodies. J. Virol. 87:6542-6550. http://dx.doi.org/10.1128/JVI.00641-13.
    • (2013) J. Virol , vol.87 , pp. 6542-6550
    • Krammer, F.1    Pica, N.2    Hai, R.3    Margine, I.4    Palese, P.5
  • 26
    • 34948848718 scopus 로고    scopus 로고
    • Complex adenovirusmediated expression of West Nile virus C, PreM, E, and NS1 proteins induces both humoral and cellular immune responses
    • Schepp-Berglind J, Luo M, Wang D, Wicker JA, Raja NU, Hoel BD, Holman DH, Barrett AD, Dong JY. 2007. Complex adenovirusmediated expression of West Nile virus C, PreM, E, and NS1 proteins induces both humoral and cellular immune responses. Clin. Vaccine Immunol. 14:1117-1126. http://dx.doi.org/10.1128/CVI.00070-07.
    • (2007) Clin. Vaccine Immunol , vol.14 , pp. 1117-1126
    • Schepp-Berglind, J.1    Luo, M.2    Wang, D.3    Wicker, J.A.4    Raja, N.U.5    Hoel, B.D.6    Holman, D.H.7    Barrett, A.D.8    Dong, J.Y.9
  • 28
    • 0034735774 scopus 로고    scopus 로고
    • Development of a preventive vaccine for Ebola virus infection in primates
    • Sullivan NJ, Sanchez A, Rollin PE, Yang ZY, Nabel GJ. 2000. Development of a preventive vaccine for Ebola virus infection in primates. Nature 408:605-609. http://dx.doi.org/10.1038/35046108.
    • (2000) Nature , vol.408 , pp. 605-609
    • Sullivan, N.J.1    Sanchez, A.2    Rollin, P.E.3    Yang, Z.Y.4    Nabel, G.J.5
  • 29
    • 4644318756 scopus 로고    scopus 로고
    • Adenoviruses as vaccine vectors
    • Tatsis N, Ertl HC. 2004. Adenoviruses as vaccine vectors. Mol. Ther. 10:616-629. http://dx.doi.org/10.1016/j.ymthe.2004.07.013.
    • (2004) Mol. Ther , vol.10 , pp. 616-629
    • Tatsis, N.1    Ertl, H.C.2
  • 30
    • 0031926451 scopus 로고    scopus 로고
    • Immunological basis for protection in a murine model of tick-borne encephalitis by a recombinant adenovirus carrying the gene encoding the NS1 nonstructural protein
    • Timofeev AV, Ozherelkov SV, Pronin AV, Deeva AV, Karganova GG, Elbert LB, Stephenson JR. 1998. Immunological basis for protection in a murine model of tick-borne encephalitis by a recombinant adenovirus carrying the gene encoding the NS1 nonstructural protein. J. Gen. Virol. 79(Pt 4):689-695.
    • (1998) J. Gen. Virol , vol.79 , pp. 689-695
    • Timofeev, A.V.1    Ozherelkov, S.V.2    Pronin, A.V.3    Deeva, A.V.4    Karganova, G.G.5    Elbert, L.B.6    Stephenson, J.R.7
  • 31
    • 27644544183 scopus 로고    scopus 로고
    • Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein
    • Epstein SL, Kong WP, Misplon JA, Lo CY, Tumpey TM, Xu L, Nabel GJ. 2005. Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein. Vaccine 23:5404-5410. http://dx.doi.org/10.1016/j.vaccine.2005.04.047.
    • (2005) Vaccine , vol.23 , pp. 5404-5410
    • Epstein, S.L.1    Kong, W.P.2    Misplon, J.A.3    Lo, C.Y.4    Tumpey, T.M.5    Xu, L.6    Nabel, G.J.7
  • 32
    • 84884579421 scopus 로고    scopus 로고
    • Mucosal vaccination with recombinant adenovirus encoding nucleoprotein provides potent protection against influenza virus infection
    • Kim SH, Kim JY, Choi Y, Nguyen HH, Song MK, Chang J. 2013. Mucosal vaccination with recombinant adenovirus encoding nucleoprotein provides potent protection against influenza virus infection. PLoS One 8:e75460. http://dx.doi.org/10.1371/journal.pone.0075460.
    • (2013) PLoS One , vol.8
    • Kim, S.H.1    Kim, J.Y.2    Choi, Y.3    Nguyen, H.H.4    Song, M.K.5    Chang, J.6
  • 35
    • 77956661888 scopus 로고    scopus 로고
    • Comparative efficacy of hemagglutinin, nucleoprotein, and matrix 2 protein gene-based vaccination against H5N1 influenza in mouse and ferret
    • Rao SS, Kong WP, Wei CJ, Van Hoeven N, Gorres JP, Nason M, Andersen H, Tumpey TM, Nabel GJ. 2010. Comparative efficacy of hemagglutinin, nucleoprotein, and matrix 2 protein gene-based vaccination against H5N1 influenza in mouse and ferret. PLoS One 5:e9812. http://dx.doi.org/10.1371/journal.pone.0009812.
    • (2010) PLoS One , vol.5
    • Rao, S.S.1    Kong, W.P.2    Wei, C.J.3    Van Hoeven, N.4    Gorres, J.P.5    Nason, M.6    Andersen, H.7    Tumpey, T.M.8    Nabel, G.J.9
  • 36
    • 84865746191 scopus 로고    scopus 로고
    • Comprehensive chemical profiling of guizhi fuling capsule by the combined use of gas chromatography-mass spectrometry with a deconvolution software and rapid-resolution liquid chromatography quadrupole time-of-flight tandem mass spectrometry
    • Wang YQ, Qi LW, Aa J, Wang GJ, Gao W, Cheng SJ, Wang ZZ, Xiao W, Li P. 2012. Comprehensive chemical profiling of guizhi fuling capsule by the combined use of gas chromatography-mass spectrometry with a deconvolution software and rapid-resolution liquid chromatography quadrupole time-of-flight tandem mass spectrometry. Biomed. Chromatogr. 26:1286-1296. http://dx.doi.org/10.1002/bmc.2695.
    • (2012) Biomed. Chromatogr , vol.26 , pp. 1286-1296
    • Wang, Y.Q.1    Qi, L.W.2    Aa, J.3    Wang, G.J.4    Gao, W.5    Cheng, S.J.6    Wang, Z.Z.7    Xiao, W.8    Li, P.9
  • 38
    • 11144258882 scopus 로고    scopus 로고
    • Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans
    • Van Kampen KR, Shi Z, Gao P, Zhang J, Foster KW, Chen DT, Marks D, Elmets CA, Tang DC. 2005. Safety and immunogenicity of adenovirus-vectored nasal and epicutaneous influenza vaccines in humans. Vaccine 23:1029-1036. http://dx.doi.org/10.1016/j.vaccine.2004.07.043.
    • (2005) Vaccine , vol.23 , pp. 1029-1036
    • Van Kampen, K.R.1    Shi, Z.2    Gao, P.3    Zhang, J.4    Foster, K.W.5    Chen, D.T.6    Marks, D.7    Elmets, C.A.8    Tang, D.C.9
  • 39
    • 16544393088 scopus 로고    scopus 로고
    • Role of mucosal immunity in influenza
    • Brandtzaeg P. 2003. Role of mucosal immunity in influenza. Dev. Biol. (Basel) 115:39-48.
    • (2003) Dev. Biol. (Basel) , vol.115 , pp. 39-48
    • Brandtzaeg, P.1
  • 40
    • 0029809510 scopus 로고    scopus 로고
    • Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization
    • Gallichan WS, Rosenthal KL. 1996. Long-lived cytotoxic T lymphocyte memory in mucosal tissues after mucosal but not systemic immunization. J. Exp. Med. 184:1879-1890. http://dx.doi.org/10.1084/jem.184.5.1879.
    • (1996) J. Exp. Med , vol.184 , pp. 1879-1890
    • Gallichan, W.S.1    Rosenthal, K.L.2
  • 41
    • 0033080256 scopus 로고    scopus 로고
    • Heterosubtypic immunity to lethal influenza A virus infection is associated with virus-specific CD8+ cytotoxic T lymphocyte responses induced in mucosa-associated tissues
    • Nguyen HH, Moldoveanu Z, Novak MJ, van Ginkel FW, Ban E, Kiyono H, McGhee JR, Mestecky J. 1999. Heterosubtypic immunity to lethal influenza A virus infection is associated with virus-specific CD8+ cytotoxic T lymphocyte responses induced in mucosa-associated tissues. Virology 254:50-60. http://dx.doi.org/10.1006/viro.1998.9521.
    • (1999) Virology , vol.254 , pp. 50-60
    • Nguyen, H.H.1    Moldoveanu, Z.2    Novak, M.J.3    van Ginkel, F.W.4    Ban, E.5    Kiyono, H.6    McGhee, J.R.7    Mestecky, J.8
  • 43
    • 0035253545 scopus 로고    scopus 로고
    • Heterosubtypic immunity to influenza A virus infection requires B cells but not CD8+ cytotoxic T lymphocytes
    • Nguyen HH, van Ginkel FW, Vu HL, McGhee JR, Mestecky J. 2001. Heterosubtypic immunity to influenza A virus infection requires B cells but not CD8+ cytotoxic T lymphocytes. J. Infect. Dis. 183:368-376. http://dx.doi.org/10.1086/318084.
    • (2001) J. Infect. Dis , vol.183 , pp. 368-376
    • Nguyen, H.H.1    van Ginkel, F.W.2    Vu, H.L.3    McGhee, J.R.4    Mestecky, J.5
  • 44
    • 84861325359 scopus 로고    scopus 로고
    • Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes
    • Hai R, Krammer F, Tan GS, Pica N, Eggink D, Maamary J, Margine I, Albrecht RA, Palese P. 2012. Influenza viruses expressing chimeric hemagglutinins: globular head and stalk domains derived from different subtypes. J. Virol. 86:5774-5781. http://dx.doi.org/10.1128/JVI.00137-12.
    • (2012) J. Virol , vol.86 , pp. 5774-5781
    • Hai, R.1    Krammer, F.2    Tan, G.S.3    Pica, N.4    Eggink, D.5    Maamary, J.6    Margine, I.7    Albrecht, R.A.8    Palese, P.9
  • 48
    • 70350567189 scopus 로고    scopus 로고
    • Vaccination focusing immunity on conserved antigens protects mice and ferrets against virulent H1N1 and H5N1 influenza A viruses
    • Price GE, Soboleski MR, Lo CY, Misplon JA, Pappas C, Houser KV, Tumpey TM, Epstein SL. 2009. Vaccination focusing immunity on conserved antigens protects mice and ferrets against virulent H1N1 and H5N1 influenza A viruses. Vaccine 27:6512-6521. http://dx.doi.org/10.1016/j.vaccine.2009.08.053.
    • (2009) Vaccine , vol.27 , pp. 6512-6521
    • Price, G.E.1    Soboleski, M.R.2    Lo, C.Y.3    Misplon, J.A.4    Pappas, C.5    Houser, K.V.6    Tumpey, T.M.7    Epstein, S.L.8
  • 49
    • 79960330452 scopus 로고    scopus 로고
    • Cold-adapted influenza and recombinant adenovirus vaccines induce cross-protective immunity against pH1N1 challenge in mice
    • Soboleski MR, Gabbard JD, Price GE, Misplon JA, Lo CY, Perez DR, Ye J, Tompkins SM, Epstein SL. 2011. Cold-adapted influenza and recombinant adenovirus vaccines induce cross-protective immunity against pH1N1 challenge in mice. PLoS One 6:e21937. http://dx.doi.org/10.1371/journal.pone.0021937.
    • (2011) PLoS One , vol.6
    • Soboleski, M.R.1    Gabbard, J.D.2    Price, G.E.3    Misplon, J.A.4    Lo, C.Y.5    Perez, D.R.6    Ye, J.7    Tompkins, S.M.8    Epstein, S.L.9
  • 50
    • 84868231731 scopus 로고    scopus 로고
    • Intranasal vaccination with replication-defective adenovirus type 5 encoding influenza virus hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs
    • Braucher DR, Henningson JN, Loving CL, Vincent AL, Kim E, Steitz J, Gambotto AA, Kehrli ME, Jr. 2012. Intranasal vaccination with replication-defective adenovirus type 5 encoding influenza virus hemagglutinin elicits protective immunity to homologous challenge and partial protection to heterologous challenge in pigs. Clin. Vaccine Immunol. 19:1722-1729. http://dx.doi.org/10.1128/CVI.00315-12.
    • (2012) Clin. Vaccine Immunol , vol.19 , pp. 1722-1729
    • Braucher, D.R.1    Henningson, J.N.2    Loving, C.L.3    Vincent, A.L.4    Kim, E.5    Steitz, J.6    Gambotto, A.A.7    Kehrli, M.E.8
  • 52
    • 0020595851 scopus 로고
    • Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity
    • Rogers GN, Paulson JC, Daniels RS, Skehel JJ, Wilson IA, Wiley DC. 1983. Single amino acid substitutions in influenza haemagglutinin change receptor binding specificity. Nature 304:76-78. http://dx.doi.org/10.1038/304076a0.
    • (1983) Nature , vol.304 , pp. 76-78
    • Rogers, G.N.1    Paulson, J.C.2    Daniels, R.S.3    Skehel, J.J.4    Wilson, I.A.5    Wiley, D.C.6
  • 53
    • 79251585956 scopus 로고    scopus 로고
    • Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection
    • El Bakkouri K, Descamps F, De Filette M, Smet A, Festjens E, Birkett A, Van Rooijen N, Verbeek S, Fiers W, Saelens X. 2011. Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection. J. Immunol. 186: 1022-1031. http://dx.doi.org/10.4049/jimmunol.0902147.
    • (2011) J. Immunol , vol.186 , pp. 1022-1031
    • El Bakkouri, K.1    Descamps, F.2    De Filette, M.3    Smet, A.4    Festjens, E.5    Birkett, A.6    Van Rooijen, N.7    Verbeek, S.8    Fiers, W.9    Saelens, X.10
  • 56
    • 81755177734 scopus 로고    scopus 로고
    • Cross-reactiveTcells are involved in rapid clearance of 2009 pandemic H1N1 influenza virus in nonhuman primates
    • Weinfurter JT, Brunner K, Capuano SV, III, Li C, Broman KW, Kawaoka Y, Friedrich TC. 2011. Cross-reactiveTcells are involved in rapid clearance of 2009 pandemic H1N1 influenza virus in nonhuman primates. PLoS Pathog. 7:e1002381. http://dx.doi.org/10.1371/journal.ppat.1002381.
    • (2011) PLoS Pathog , vol.7
    • Weinfurter, J.T.1    Brunner, K.2    Capuano, S.V.3    Li, C.4    Broman, K.W.5    Kawaoka, Y.6    Friedrich, T.C.7
  • 57
    • 0031066918 scopus 로고    scopus 로고
    • Mechanisms of heterosubtypic immunity to lethal influenza A virus infection in fully immunocompetent, T cell-depleted, β2-microglobulin-deficient, and J-chain-deficient mice
    • Epstein SL, Lo CY, Misplon JA, Lawson CM, Hendrickson BA, Max EE, Subbarao K. 1997. Mechanisms of heterosubtypic immunity to lethal influenza A virus infection in fully immunocompetent, T cell-depleted, β2-microglobulin-deficient, and J-chain-deficient mice. J. Immunol. 158: 1222-1230.
    • (1997) J. Immunol , vol.158 , pp. 1222-1230
    • Epstein, S.L.1    Lo, C.Y.2    Misplon, J.A.3    Lawson, C.M.4    Hendrickson, B.A.5    Max, E.E.6    Subbarao, K.7
  • 58
    • 84885953445 scopus 로고    scopus 로고
    • Influenza virus hemagglutinin stalk-based antibodies and vaccines
    • Krammer F, Palese P. 2013. Influenza virus hemagglutinin stalk-based antibodies and vaccines. Curr. Opin. Virol. 3:521-530. http://dx.doi.org/10.1016/j.coviro.2013.07.007.
    • (2013) Curr. Opin. Virol , vol.3 , pp. 521-530
    • Krammer, F.1    Palese, P.2
  • 59
    • 56149115867 scopus 로고    scopus 로고
    • Nasal delivery of an adenovirus-based vaccine bypasses preexisting immunity to the vaccine carrier and improves the immune response in mice
    • Croyle MA, Patel A, Tran KN, Gray M, Zhang Y, Strong JE, Feldmann H, Kobinger GP. 2008. Nasal delivery of an adenovirus-based vaccine bypasses preexisting immunity to the vaccine carrier and improves the immune response in mice. PLoS One 3:e3548. http://dx.doi.org/10.1371/journal.pone.0003548.
    • (2008) PLoS One , vol.3
    • Croyle, M.A.1    Patel, A.2    Tran, K.N.3    Gray, M.4    Zhang, Y.5    Strong, J.E.6    Feldmann, H.7    Kobinger, G.P.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.