Sinomenine suppresses collagen-induced arthritis by reciprocal modulation of regulatory T cells and Th17 cells in gut-associated lymphoid tissues

Molecular Immunology

Volumn 65, Issue 1, 2015, Pages 94-103

  Tong, Bei ^a   Yu, Juntao ^a   Wang, Ting ^a   Dou, Yannong ^a   Wu, Xin ^a   Kong, Lingyi ^a   Dai, Yue ^a   Xia, Yufeng ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

CIA; Gut associated lymphoid tissues; Sinomenine; Th17 cell; Treg cell

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 17; SINOMENINE; TRANSCRIPTION FACTOR FOXP3; ANTIINFLAMMATORY AGENT; COLLAGEN; IL17 PROTEIN, RAT; MORPHINAN DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTHRITIS; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISTRIBUTION HALF-LIFE; DOWN REGULATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG MECHANISM; FEMALE; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE LYMPHATIC TISSUE; LYMPHOCYTE PROLIFERATION; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; RAT; REGULATORY MECHANISM; REGULATORY T LYMPHOCYTE; TH17 CELL; UPREGULATION; VOLUME OF DISTRIBUTION; ANIMAL; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; BIOSYNTHESIS; CELL DIFFERENTIATION; CHEMICALLY INDUCED; CYTOLOGY; GASTROINTESTINAL TRACT; IMMUNOLOGY; LYMPH NODE; WISTAR RAT;

RATTUS;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; CELL DIFFERENTIATION; COLLAGEN; GASTROINTESTINAL TRACT; INTERLEUKIN-10; INTERLEUKIN-17; LYMPH NODES; MORPHINANS; RATS; RATS, WISTAR; T-LYMPHOCYTES, REGULATORY; TH17 CELLS;

EID: 84921957794     PISSN: 01615890     EISSN: 18729142     Source Type: Journal    
DOI: 10.1016/j.molimm.2015.01.014     Document Type: Article

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