Pharmacokinetics and efficiency of brain targeting of ginsenosides Rg1 and Rb1 given as Nao-Qing microemulsion

Drug Development and Industrial Pharmacy

Volumn 41, Issue 2, 2015, Pages 224-231

  Li, Tao ^a   Shu, Ya Jun ^b   Cheng, Jia Yin ^b   Liang, Run Cheng ^b   Dian, Shao Na ^a   Lv, Xiao Xun ^b   Yang, Meng Qi ^b   Huang, Shu Ling ^b   Chen, Gang ^b   Yang, Fan ^b  

^a GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Brain targeting; Ginsenoside Rg1; Intranasal administration; Microemulsion; Nao Qing; Pharmacokinetic

Indexed keywords

GINSENOSIDE RB 1; GINSENOSIDE RG 1; EMULSION; GINSENOSIDE; HERBACEOUS AGENT;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD BRAIN BARRIER; BLOOD SAMPLING; BRAIN; CONTROLLED STUDY; DRUG CLEARANCE; DRUG HALF LIFE; DRUG TARGETING; FIRST PASS EFFECT; HEART; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; KIDNEY; LIVER; LUNG; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MICROEMULSION; NAO QING MICROEMULSION; NONHUMAN; PARTICLE SIZE; PH; PLASMA CONCENTRATION-TIME CURVE; PROTEIN BINDING; RAT; TIME TO MAXIMUM PLASMA CONCENTRATION; TISSUE DISTRIBUTION; VISCOSITY; VOLUME OF DISTRIBUTION; ANIMAL; EMULSION; HUMAN; INTRANASAL DRUG ADMINISTRATION; MEDICINAL CHEMISTRY; METABOLISM; PHYTOTHERAPY; SPRAGUE DAWLEY RAT; STROKE;

ADMINISTRATION, INTRANASAL; ANIMALS; BLOOD-BRAIN BARRIER; BRAIN; CHEMISTRY, PHARMACEUTICAL; DRUGS, CHINESE HERBAL; EMULSIONS; GINSENOSIDES; HUMANS; PHYTOTHERAPY; RATS; RATS, SPRAGUE-DAWLEY; STROKE;

EID: 84921930697     PISSN: 03639045     EISSN: 15205762     Source Type: Journal    
DOI: 10.3109/03639045.2013.858734     Document Type: Article

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