Cognitive behavioral therapies in older adults with depression and cognitive deficits: A systematic review

International Journal of Geriatric Psychiatry

Volumn 30, Issue 3, 2015, Pages 223-233

  Simon, Sharon Sanz ^a   Cordás, Táki Athanássios ^a   Bottino, Cássio M C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Aging; Cognitive behavioral therapy; Cognitive deficits; Depression; Problem solving therapy; Psychotherapy

Indexed keywords

AGING; BEHAVIOR THERAPY; BRAIN FUNCTION; COGNITIVE DEFECT; COGNITIVE THERAPY; DEPRESSION; DISABILITY; EXECUTIVE FUNCTION; FOLLOW UP; HUMAN; MEDICAL INFORMATION; MEDLINE; MOOD; PROBLEM SOLVING; PSYCHOTHERAPY; PSYCINFO; REVIEW; SKILL; SYSTEMATIC REVIEW; AGED; COGNITION DISORDERS; DEPRESSIVE DISORDER; DISABLED PERSON; PROCEDURES; PSYCHOLOGY;

AGED; COGNITION DISORDERS; COGNITIVE THERAPY; DEPRESSIVE DISORDER; DISABLED PERSONS; EXECUTIVE FUNCTION; HUMANS; PROBLEM SOLVING;

EID: 84921876208     PISSN: 08856230     EISSN: 10991166     Source Type: Journal    
DOI: 10.1002/gps.4239     Document Type: Review

References (80)

1. Adler G, Chwalek K, Jajcevic A. 2004. Six-month course of mild cognitive impairment and affective symptoms in late-life depression. Eur Psychiatry 19: 502-505.
2. Aizenstein HJ, Khalaf A, Walker SE, Andreescu C. 2014. MRI Predictors of Treatment Response in Late-Life Depression. Psychiatr Neurol 27(1): 24-32. DOI: 10.1177/0891988713516541.
3. Alexopoulos GS. 2005. Depression in the elderly. Lancet 365: 1961-1970.
4. Alexopoulos GS, Areán P. 2014. A model for streamlining psychotherapy in the RDoC era: the example of 'Engage'. Mol Psychiatry 19: 14-19. DOI: 10.1038/mp.2013.150.
5. Alexopoulos GS, Meyers BS, Young RC, et al. 1997. Clinically defined vascular depression. Am J Psychiatr 154: 562-565.
6. Alexopoulos GS, Kiosses DN, Klimstra S, Kalayam B, Bruce ML. 2002. Clinical presentation of the "depression-executive dysfunction syndrome" of late life. Am J Geriatr Psychiatry 10 (1): 98-106.
7. Alexopoulos GS, Raue P, Areán P. 2003. Problem-Solving Therapy Versus Supportive Therapy in Geriatric Major Depression With Executive Dysfunction. Am J Geriatr Psychiatry 11(1): 46-52.
8. Alexopoulos GS, Kiosses DN, Heo M, et al . 2005. Executive Dysfunction and the Course of Geriatric Depression. Biol Psychiatry 58(3): 204-210. DOI: 10.1016/j.biopsych.2005.04.024.
9. Alexopoulos GS, Murphy CF, Gunning-Dixon FM, et al. 2008a. Microstructural white matter abnormalities and remission of geriatric depression. Am J Psychiatry 165: 238-244. DOI: 10.1176/appi.ajp.2007.07050744
10. Alexopoulos GS, Raue PJ, Kanellopoulos D, Mackin S, Areán PA. 2008b. Problem solving therapy for the depression-executive dysfunction syndrome of late life. Int J Geriatr Psychiatry 23 (8): 782-788. DOI: 10.1002/gps.1988
11. Alexopoulos GS, Raue PJ, Kiosses DN, et al. 2011. Problem Solving Therapy and Supportive Therapy in Older Adults with Major Depression and Executive Dysfunction: Effect on Disability. Arch Gen Psychiatry 68(1): 33-41. DOI: 10.1001/archgenpsychiatry.2010.177.
12. Andreescu C, Butters MA, Begley A, et al. 2008. Gray matter changes in late life depression - a structural MRI analysis. Neuropsychopharmacology 33(11): 2566-2572. DOI: 10.1038/sj.npp.1301655
13. Areán PA, Hegel M, Vannoy S, Fan MY, Unuzter J. 2008. Effectiveness of problem-solving therapy for older, primary care patients with depression: results from the IMPACT project. Gerontologist 48(3): 311-323.
14. Areán PA, Mackin S, Vargas-Dwyer E, et al. 2010a. Treating Depression in Disabled, Low-income Elderly: A Conceptual Model and Recommendations for Care. Int J Geriatr Psychiatry 25(8): 765-769. DOI: 10.1002/gps.2556.
15. Areán PA, Raue P, Mackin RS, et al . 2010b. Problem-Solving Therapy and Supportive Therapy in Older Adults with Major Depression and Executive Dysfuncttion. Am J Psychiatry 167: 1391-1398. DOI: 10.1176/appi.ajp.2010.09091327.
16. Bahar-Fuchs A, Clare L, Woods B. 2013. Cognitive training and cognitive rehabilitation for mild to moderate Alzheimer's disease and vascular dementia. Cochrane Database Syst Rev 6: CD003260. DOI: 10.1002/14651858.CD003260.pub2.
17. Beck AT. 2005. The current state of cognitive therapy: a 40-year retrospective. Arch Gen Psychiatry 62(9): 953-959.
18. Bell AC, D'Zurilla TJ. 2009. Problem-solving therapy for depression: A meta-analysis. Clin Psychol Rev 29(4): 348-353. DOI: 10.1016/j.cpr.2009.02.003.
19. Benjamin S, Steffens DC. 2011. Structural Neuroimaging of Geriatric Depression. Psychiatr Clin North Am 34(2): 423-435, ix. DOI: 10.1016/j.psc.2011.02.001.
20. Bruce ML. 2002. Psychosocial risk factors for depressive disorders in late life. Biol Psychiatry 52: 175-184.
21. Bruce ML, Seeman TE, Merrill SS, Blazer DG. 1994. The impact of depressive symptomatology on physical disability: MacArthur Studies of Successful Aging. Am J Public Health 84: 1796-1799.
22. Butters MA, Becker JT, Nebes RD, et al. 2000. Changes in cognitive functioning following treatment of late-life depression. Am J Psychiatry 157: 1949-1954.
23. Butters MA, Whyte EM, Nebes RD, et al. 2004. The nature and determinants of neuropsychological functioning in late-life depression. Arch Gen Psychiatry 61: 587-595.
24. Cronin-Stubbs D1, deLeon CF, Beckett LA. 2000. Six-year effect of depressive symptoms on the course of physical disability in community-living older adults. Arch Intern Med 13: 3074-3080.
25. Cuijpers P, van Straten A, Smit F. 2006. Psychological treatment of late-life depression: a meta-analysis of randomized controlled trials. Int J Geriatr Psychiatry 21: 1139-1149.
26. Cuijpers P, Karyotaki E, Pot AM, Park M, Reynolds CF 3rd. 2014. Managing depression in older age: psychological interventions. Maturitas 79(2): 160-169. DOI: 10.1016/j.maturitas.2014.05.027.
27. Dalle CL, Maggi S, Noale M, et al. 2009. ILSA Working Group. Physical disability and depressive symptomatology in an elderly population: a complex relationship. The Italian Longitudinal Study on Aging (ILSA). Am J Geriatr Psychiatry 17(2): 144-154.
28. Diniz BS, Butters MA, Albert SM, Dew MA, Reynolds CF. 3rd. 2013. Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies. Br J Psychiatry 202: 329-335. DOI: 10.1192/bjp.bp.112.118307.
29. Elderkin-Thompson V, Kumar A, Bilker WB, et al. 2003. Neuropsychological déficits among patients with late-onset minor and major depression. Arch Clin Neuropsychol 18(5): 529-549.
30. Ferrari AJ, Charlson FJ, Norman RE, et al . 2013. Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010. PLoS Med 10(11): 1-12. DOI: 10.1371/journal.pmed.1001547.
31. Gellis ZD, McGinty J, Horowitz A, Bruce ML, Misener E. 2007. Problem Solving Therapy for Late-life Depression in home Care: A Randomized Field Trial. Am J Geriatr Psychiatry 15 (11): 968-978.
32. Hampstead BM, Gillid MM, Stringer AY. 2014. Cognitive Rehabilitation of Memory for Mild Cognitive Impairment: A Methodological Review and Model for Future Research. J Int Neuropsychol Soc 20(2): 135-151. DOI: 10.1017/S1355617713001306.
33. Haverkamp R, Areán P, Hegel MT, Unützer J. 2004. Problem-solving treatment for complicated depression in late life: a case study in primary care. Perspect Psychiatry 40(2): 45-52.
34. Kennedy GJ. 2001. The dynamics of depression and disability. Am J Geriatr Psychiatry 9(2): 99-101.
35. Kiosses DN, Alexopoulos GS. 2005. IADL functions, cognitive deficits, and severity of depression: a preliminary study. Am J Geriatr Psychiatry 13 (3): 244-249.
36. Kiosses DN, Ravdin LD. 2010. Psychosocial Interventions for Depressed Older Adults With Cognitive Impairment and Disability Improving Functionality and Quality of Life. Psychiatr Times 30(5): 1.
37. Kiosses DN, Alexopoulos GS. 2014. Problem-Solving Therapy in the Elderly. Curr Treat Options Psychiatry 1(1): 15-26.
38. Kiosses DN, Klimstra S, Murphy C, Alexopoulos GS. 2001. Executive dysfunction and disability in elderly patients withmajor depression. Am J Geriatr Psychiatry 9: 269-274.
39. Kiosses DN, Arean PA, Teri L, Alexopoulos GS. 2010. Home-delivered Problem Adaptation Therapy (PATH) for Depressed, Cognitively Impaired, Disabled Elders: A Preliminary Study. Am J Geriatr Psychiatry 18(11): 988-998.
40. Kiosses DN, Leon AC, Areán PA. 2011a. Psychosocial Interventions for the Acute Treatment of Late-life Major Depression: A Systematic Review of Evidence-based Treatments, Predictors of Treatment Outcomes and Moderators of Treatment Effects. Psychiatr Clin North Am 34(2): 377-401. DOI: 10.1016/j.psc.2011.03.001.
41. Kiosses DN, Teri L, Velligan DI, Alexopoulos GS. 2011b. A home delivered intervention for depressed, cognitively impaired, disabled elders. Int J Geriatr Psychiatry 26(3): 256-262. DOI: 10.1002/gps.2521.
42. Kittur SD, Ruskin R. 2001. Environmental modification for treatment of agitation in Alzheimer's patients. Neurorehabilitation 12: 211-214.
43. Koenig AM, Butters MA. 2014. Cognition in Late Life Depression: Treatment Considerations. Curr Treat Options Psychiatry 1(1): 1-14.
44. Kohler S, Thomas AJ, Barnett NA, O'Brien JT. 2010. The pattern and course of cognitive impairment in late-life depression. Psychol Med 40(4): 591-602. DOI: 10.1017/S0033291709990833
45. Laidlaw K, Thompson LW, Gallagher-Thompson D, Dick-Siskin L. 2003. Cognitive behaviour therapy with older people. John Wiley & Sons, Ltd.: Chichester.
46. Li H, Li J, Li N, et al. 2011. Cognitive intervention for persons with mild cognitive impairment: A meta-analysis. Ageing Res Rev 10(2): 285-296. DOI: 10.1016/j.arr.2010.11.003.
47. Mackin RS, Areán P. 2005. Evidence-based psychotherapeutic interventions for geriatric depression. Psychiatr Clin North Am 28(4): 805-820.
48. Mackin RS, Tosun D, Mueller SG, et al. 2013a. Patterns of Reduced Cortical Thickness in Late-Life Depression and Relationship to Psychotherapeutic Response. Am J Geriatr Psychiatry 21(8): 794-802. DOI: 10.1016/j.jagp.2013.01.013.
49. Mackin RS, Nelson JC, Delucchi K, et al. 2013b. Cognitive Outcomes after Psychotherapeutic Interventions for Major Depression in Older Adults with Executive Dysfunction. Am J Geriatr Psychiatry S1064-7481(13)00413-2. DOI: 10.1016/j.jagp.2013.11.002.
50. Mackin RS, Nelson JC, Delucchi KL, et al. 2014. Association of Age at Depression Onset with Cognitive Functioning in Individuals with Late-Life Depression and Executive Dysfunction. Am J Geriatr Psychiatry S1064-7481(14)00076-1. DOI: 10.1016/j.jagp.2014.02.006.
51. Marquett RM, Thompson LW, Reiser RP. 2013. Psychosocial predictors of treatment response to cognitive-behavior therapy for late-life depression: an exploratory study. Aging Ment Health 17(7): 830-838. DOI: 10.1080/13607863.2013.791661.
52. McIntyre RS, Cha DS, Soczynska JK, et al . 2013. Cognitive deficits and functional outcomes in major depressive disorder: determinants, substrates, and treatment interventions. Depress Anxiety 30(6): 515-527. DOI: 10.1002/da.22063.
53. Mohlman J. 2005. Does executive dysfunction affect treatment outcome in late-life mood and anxiety disorders? J Geriatr Psychiatry Neurol 18(2): 97-108.
54. Morimoto SS, Wexler BE, Alexopoulos GS. 2012. Neuroplasticity-Based Computerized Cognitive Remediation for Geriatric Depression. Int J Geriatr Psychiatry 27(12): 1239-1247. DOI: 10.1002/gps.3776.
55. Mowszowski L, Batchelor J, Naismith SL. 2010. Early intervention for cognitive decline. Can cognitive training be used as a selective prevention technique? Int Psychogeriatr 22: 537-548.
56. Naismith SL, Hickie IB, Ward PB, Scott E, Little C. et al. 2006. Impaired implicit sequence learning in depression: a probe for frontostriatal dysfunction? Psychol Med 36: 313-323.
57. Naismith SL, Diamond K, Carter PE, et al. 2011. Enhancing memory in late-life depression: the effects of a combined psychoeducation and cognitive training program. Am J Geriatr Psychiatry 19: 240-248.
58. Naismith SL, Norrie LM, Mowszowski L, Hickie IB. 2012. The neurobiology of depression in later-life: clinical, neuropsychological, neuroimaging and pathopshysiological features. Prog Neurobiol 98 (1): 99-143. DOI: 10.1016/j.pneurobio.2012.05.009.
59. Nebes RD, Pollock BG, Houck PR, et al. 2003. Persistence of cognitive impairment in geriatric patients following antidepressant treatment: a randomized, double-blind clinical trial with nortriptyline and paroxetine. J Psychiatr Res 37: 99-100.
60. Nezu AM. 1987. A problem-solving formulation of depression: a literature review and proposal of a pluralistic model. Clin Psychol Rev 7(2): 121-144.
61. O'Shea DM, Fieo RA, Hamilton JL, et al. 2014. Examining the association between late-life depressive symptoms, cognitive function, and brain volumes in the context of cognitive reserve. Int J Geriatr Psychiatry . DOI: 10.1002/gps.4192.
62. Paukert A, Phillips L, Cully JA, et al . 2009. Integration of religion into cognitive-behavioral therapy for geriatric anxiety and depression. J Psychiatr Pract 15: 103-112.
63. Payman V. 2011. Psychitherapeutic treatments in late life. Curr Opin Psychiatry 24(6): 484-488. DOI: 10.1097/YCO.0b013e32834a58bb.
64. Pinquart M, Duberstein PR, Lyness JM. 2007. Effects of psychotherapy and other behavioral interventions on clinically depressed older adults: a meta-analysis. Aging Ment Health 11(6): 645-657.
65. Potter GG, Steffens DC. 2007. Contribution of depression to cognitive im- pairment and dementia in older adults. Neurologist 13: 105-117.
66. Potter GG, Kittinger JD, Wagner HR, Steffens DC, Krishnan KR. 2004. Prefrontal neuropsychological predictors of treatment remission in late-life depression. Neuropsychopharmacology 29: 2266-2271.
67. Raskin J, Wiltse CG, Siegal A, et al. 2007. Efficacy of duloxetine on depressive disorder: an 8-week, double-blind, placebo-controlled trial. Am J Psychiatry 164: 900-909.
68. Safer DL, Hugo EM. 2006 Designing a Control for a Behavioral Group Therapy. Behav Ther 37(2): 120-130.
69. Sharpe L, Gittins CB, Correia HM, et al. 2012. Problem-solving versus cognitive restructuring of medically ill seniors with depression (PROMISE-D trial): study protocol and design. BMC Psychiatry 12: 207. DOI: 10.1186/1471-244X-12-207.
70. Sheline YI, Barch DM, Garcia K, et al. 2006. Cognitive function in late life depression: relationships to depression severity, cerebrovascular risk factors and processing speed. Biol Psychiatry 60: 58-65.
71. Simon SS, Yokomizo JE, Bottino CMC. 2012. Cognitive intervention in amnestic Mild Cognitive Impairment: A systematic review. Neurosci Biobehav Rev 36: 1163-1178. DOI: 10.1016/j.neubiorev.2012.01.007.
72. Sneed JR, Roose SP, Keilp JG, et al . 2007. Response inhibition predicts poor antidepressant treatment response in very old depressed patients. Am J Geriatr Psychiatry 15: 553-563.
73. Stangier U, Hilling C, Heidenreich T, et al. 2013. Maintenance Cognitive-Behavioral Therapy and Manualized Psychoeducation in the Treatment of Recurrent Depression: A Multicenter Prospective Randomized Controlled Trial. Am J Psychiatry 170: 624-632. DOI: 10.1176/appi.ajp.2013.12060734.
74. Teri L, Logsdon RG, Uomoto J, McCurry SM. 1997. Behavioral treatment of depression in dementia patients: a controlled clinical trial. J Gerontol B Psychol Sci Soc Sci 52: 159-166.
75. Thompson LW, Coon DW, Gallagher-Thompson D, Sommer BR, Koin D. 2001. Comparison of desipramine and cognitive/behavioral therapy in the treatment of elderly outpatients with mild-to-moderate depression. Am J Geriatr Psychiatry 9: 225-240.
76. Unützer J, Katon W, Callahan CM, et al. 2002. Collaborative care management of late-life depression in the primary care setting. A randomized controlled trial. JAMA 288: 2836-2845.
77. Wang L, et al. 2012. Neural Correlates Associated with Cognitive Decline in Late-life Depression. Am J Geriatr Psychiatry 20(8): 653-663. DOI: 10.1097/JGP.0b013e31823e2cc7.
78. Wiles N, Thomas L, Abel A, et al. 2013. Cognitive behavioural therapy as an adjunct to pharmacotherapy for primary care based patients with treatment resistant depression: results of the CoBalT randomised controlled trial. Lancet 381(9864): 375-384. DOI: 10.1016/S0140-6736(12)61552-9.
79. Wilkins CH, Mathews J, Sheline YI. 2009. Late life depression with cognitive impairment: evaluation and treatment. Clin Interv Aging 4: 51-57.
80. Wilkins VM, Kiosses D, Ravdin LD. 2010. Late-life depression with comorbid cognitive impairment and disability: nonpharmacological interventions. Clin Interv Aging 5: 323-331.