Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 4, 2015, Pages 1119-1124

  Afzal, Samia ^a,b   Hao, Zhenyue ^b   Itsumi, Momoe ^b,c   Abouelkheer, Yasser ^b   Brenner, Dirk ^b,d   Gao, Yunfei ^b   Wakeham, Andrew ^b   Hong, Claire ^b   Li, Wanda Y ^b   Sylvester, Jennifer ^b   Gilani, Syed O ^b   Brüstle, Anne ^b,e   Haight, Jillian ^b   You Ten, Annick J ^b   Lin, Gloria H Y ^b   Inoue, Satoshi ^b   Mak, Tak W ^a,b  

^a UNIVERSITY OF TORONTO   (Canada)

^b University Health Network   (Canada)

^c KYUSHU UNIVERSITY   (Japan)

^d LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

^e AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

Autophagy; Embryonic lethality; T cell homeostasis; UVRAG deficient mice

Indexed keywords

ANIMAL CELL; ARTICLE; AUTOPHAGY; CD8+ T LYMPHOCYTE; CELL DEATH; CELL LINE; CELL PROLIFERATION; CONTROLLED STUDY; EMBRYO; GENE; GENE DELETION; GENE EXPRESSION; HOMEOSTASIS; HOMOZYGOSITY; IN VIVO STUDY; INFECTION; LETHALITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; ULTRAVIOLET RADIATION RESISTANCE ASSOCIATED GENE; VIRAL CLEARANCE; ANIMAL; CELLULAR IMMUNITY; GENETICS; IMMUNOLOGY; ISOLATION AND PURIFICATION; KNOCKOUT MOUSE; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; PATHOLOGY;

LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MUS;

TUMOR SUPPRESSOR PROTEIN; UVRAG PROTEIN, MOUSE;

ANIMALS; AUTOPHAGY; CD8-POSITIVE T-LYMPHOCYTES; GENE DELETION; HOMEOSTASIS; IMMUNITY, CELLULAR; LYMPHOCYTIC CHORIOMENINGITIS; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MICE; MICE, KNOCKOUT; TUMOR SUPPRESSOR PROTEINS;

EID: 84921809383     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1423588112     Document Type: Article

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