-
2
-
-
0026682798
-
Stability of K-ras mutations throughout the natural history of human colorectal cancer bur
-
Losi L, Benhattar J, Costa J Stability of K-ras mutations throughout the natural history of human colorectal cancer bur J Cancer 1992, 28A. 1115-1120
-
(1992)
J Cancer
, vol.28 A
, pp. 1115-1120
-
-
Losi, L.1
Benhattar, J.2
Costa, J.3
-
3
-
-
0026658820
-
K-ras point mutations in human colorectal carcinomas relation to aneuploidy and metastasis
-
Suchy B, Zietz C, Rabes HM: K-ras point mutations in human colorectal carcinomas relation to aneuploidy and metastasis Int J Cancer 1992; 52-30-33
-
(1992)
Int J Cancer
, vol.52
, pp. 30-33
-
-
Suchy, B.1
Zietz, C.2
Rabes, H.M.3
-
4
-
-
0028596162
-
The common molecular genetic alterations in Dukes' B and C colorectal carcinomas are not short-term prognostic indicators of survival
-
Dix BR, Robbins P, Soong R., et al.: The common molecular genetic alterations in Dukes' B and C colorectal carcinomas are not short-term prognostic indicators of survival Int J Cancer 1994; 59. 747-751
-
(1994)
Int J Cancer
, vol.59
, pp. 747-751
-
-
Dix, B.R.1
Robbins, P.2
Soong, R.3
-
5
-
-
0027732538
-
Proteins regulating Ras and its relatives
-
Boguski MS, McCormick F: Proteins regulating Ras and its relatives. Nature 1993, 366, 643-654.
-
(1993)
Nature
, vol.366
, pp. 643-654
-
-
Boguski, M.S.1
McCormick, F.2
-
6
-
-
0037810249
-
Signal transduction mediated by the Ras/Rat/MEK/ERK pathway from cytokine receptors to transcription factors, potential targeting for therapeutic intervention
-
Chang F, Steelman LS, Lee J.T., et al.: Signal transduction mediated by the Ras/Rat/MEK/ERK pathway from cytokine receptors to transcription factors, potential targeting for therapeutic intervention Leukemia 2003, 17 1263-1293
-
(2003)
Leukemia
, vol.17
, pp. 1263-1293
-
-
Chang, F.1
Steelman, L.S.2
Lee, J.T.3
-
7
-
-
65949119310
-
How ERK1/2 activation controls cell proliferation and cell death Is subcellular localization the answer?
-
Mebratu Y, Tesfaigzi Y: How ERK1/2 activation controls cell proliferation and cell death Is subcellular localization the answer? Cell Cycle 2009; 8 1168-1175
-
(2009)
Cell Cycle
, vol.8
, pp. 1168-1175
-
-
Mebratu, Y.1
Tesfaigzi, Y.2
-
8
-
-
33746565515
-
Role of Raf kinase in cancer therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway
-
Gollob JA, Wilhelm S, Carter C., et al.: Role of Raf kinase in cancer therapeutic potential of targeting the Raf/MEK/ERK signal transduction pathway Semin Oncol 2006, 33 392-406
-
(2006)
Semin Oncol
, vol.33
, pp. 392-406
-
-
Gollob, J.A.1
Wilhelm, S.2
Carter, C.3
-
9
-
-
63849088630
-
Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer
-
Cutsem EV, Kohne CH, Hitre E, et al.: Cetuximab and chemotherapy as initial treatment for metastatic colorectal cancer N Eng J Med 2009, 360 1408-1417.
-
(2009)
N Eng J Med
, vol.360
, pp. 1408-1417
-
-
Cutsem, E.V.1
Kohne, C.H.2
Hitre, E.3
-
10
-
-
0032490124
-
Kirsten ras mutations in patients with colorectal cancer the multicenter "RASCAL" study
-
Andreyev HJ, Norman AR, Cunningham D, et al.: Kirsten ras mutations in patients with colorectal cancer the multicenter "RASCAL" study J Natl Cancer Inst 1998, 90(9) 675-684
-
(1998)
J Natl Cancer Inst
, vol.90
, Issue.9
, pp. 675-684
-
-
Andreyev, H.J.1
Norman, A.R.2
Cunningham, D.3
-
11
-
-
0035444798
-
Kirsten ras mutations in patients with colorectal cancer the 'RASCAL 11' study
-
Andreyev HJ, Norman AR, Cunningham D, et al.: Kirsten ras mutations in patients with colorectal cancer the 'RASCAL 11' study. Br J Cancer 2001, 85(5) 692-696
-
(2001)
Br J Cancer
, vol.85
, Issue.5
, pp. 692-696
-
-
Andreyev, H.J.1
Norman, A.R.2
Cunningham, D.3
-
12
-
-
79956310674
-
Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer the OPUS study
-
Bokemeyer C, Bondarenko I, Hartman J.T., et al.: Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer the OPUS study Ann Oncol 2011, 22 1535-1546
-
(2011)
Ann Oncol
, vol.22
, pp. 1535-1546
-
-
Bokemeyer, C.1
Bondarenko, I.2
Hartman, J.T.3
-
13
-
-
42649145667
-
Wild-type KRAS is required for pamtumumab efficacy in patients with metastatic colorectal cancer
-
Amado RG, Wolf M, Peeters M., et al.: Wild-type KRAS is required for pamtumumab efficacy in patients with metastatic colorectal cancer J Clin Oncol 2008, 26 1626-1634
-
(2008)
J Clin Oncol
, vol.26
, pp. 1626-1634
-
-
Amado, R.G.1
Wolf, M.2
Peeters, M.3
-
14
-
-
61449202998
-
The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer
-
Hurwitz HI, Yi J, Ince W., et al.: The clinical benefit of bevacizumab in metastatic colorectal cancer is independent of K-ras mutation status analysis of a phase III study of bevacizumab with chemotherapy in previously untreated metastatic colorectal cancer Oncologist 2009, 14(1) 22-28
-
(2009)
Oncologist
, vol.14
, Issue.1
, pp. 22-28
-
-
Hurwitz, H.I.1
Yi, J.2
Ince, W.3
-
15
-
-
24944525406
-
Determination of TP53 mutation is more relevant that microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients
-
Westra JL, Schaapveld M, Hollema H., et al.: Determination of TP53 mutation is more relevant that microsatellite instability status for the prediction of disease-free survival in adjuvant-treated stage III colon cancer patients J Clin Oncol 2005; 23:5635-5643
-
(2005)
J Clin Oncol
, vol.23
, pp. 5635-5643
-
-
Westra, J.L.1
Schaapveld, M.2
Hollema, H.3
-
16
-
-
75749102647
-
Prognostic role of KRAS and BRAF in stage II and III resected colon cancer results of the translational study on the PETACC-3, EORTC 40933, SAKK 60-00 trial
-
Roth A, Tejpar S, Delorenzi M., et al.: Prognostic role of KRAS and BRAF in stage II and III resected colon cancer results of the translational study on the PETACC-3, EORTC 40933, SAKK 60-00 trial. J Clin Oncol 2009, 28. 466-474
-
(2009)
J Clin Oncol
, vol.28
, pp. 466-474
-
-
Roth, A.1
Tejpar, S.2
Delorenzi, M.3
-
17
-
-
0032032984
-
The type of K-ras mutation determines prognosis in colorectal cancer
-
Cerottini JP, Caplin S, Saraga E., et al.: The type of K-ras mutation determines prognosis in colorectal cancer. Am J Surg 1998; 175(3)198-202.
-
(1998)
Am J Surg
, vol.175
, Issue.3
, pp. 198-202
-
-
Cerottini, J.P.1
Caplin, S.2
Saraga, E.3
-
18
-
-
84868340002
-
K-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecanor oxahplatinbased chemotherapy
-
Stec R, Bodnar L, Charkiewicz R., et al.: K-Ras gene mutation status as a prognostic and predictive factor in patients with colorectal cancer undergoing irinotecanor oxahplatinbased chemotherapy Cancer Biol Ther 2012; 13(13);1235-1243
-
(2012)
Cancer Biol Ther
, vol.13
, Issue.13
, pp. 1235-1243
-
-
Stec, R.1
Bodnar, L.2
Charkiewicz, R.3
-
19
-
-
78149250536
-
Phase III trial of panitumumab with infusional fluorouracil, leucovorm, and oxahplatin [F0LF0X4] versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer the PRIME study
-
Douillard JY, Siena S, Cassidy J., et al.: Phase III trial of panitumumab with infusional fluorouracil, leucovorm, and oxahplatin [F0LF0X4] versus FOLFOX4 alone as first-line treatment in patients with previously untreated metastatic colorectal cancer the PRIME study J Clin Oncol 2010; 28(31). 4697-4705.
-
(2010)
J Clin Oncol
, vol.28
, Issue.31
, pp. 4697-4705
-
-
Douillard, J.Y.1
Siena, S.2
Cassidy, J.3
-
20
-
-
84867411491
-
Role of Kras status in patients with metastatic colorectal cancer receiving first-line chemotherapy plus bevacizumab a TTD group cooperative study
-
Diaz-Rubio E, Gomez-Espana A, Massuti B., et al.: Role of Kras status in patients with metastatic colorectal cancer receiving first-line chemotherapy plus bevacizumab a TTD group cooperative study. PLoS One 2012, 7(10). e4735
-
(2012)
PLoS One
, vol.7
, Issue.10
-
-
Diaz-Rubio, E.1
Gomez-Espana, A.2
Massuti, B.3
|