Neurogenic niches in the brain: Help and hindrance of the barrier systems

Frontiers in Neuroscience

Volumn 9, Issue JAN, 2015, Pages

  Stolp, Helen B ^a   Molnár, Zoltán ^b  

^a KING'S COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Blood brain barrier; Cerebrospinal fluid; Cerebrovasculature; Choroid plexus; Neurogenesis; Neurogenic niche; Neuronal progenitors

Indexed keywords

BLOOD BRAIN BARRIER; BRAIN NERVE CELL; CELL COMMUNICATION; CELL INTERACTION; CELL PROLIFERATION; CEREBROSPINAL FLUID; HUMAN; NERVOUS SYSTEM DEVELOPMENT; REVIEW; STEM CELL; SUBVENTRICULAR ZONE; TELENCEPHALON;

EID: 84921758505     PISSN: 16624548     EISSN: 1662453X     Source Type: Journal    
DOI: 10.3389/fnins.2015.00020     Document Type: Review

References (56)

1. Alvarez, J. I., A. Dodelet-Devillers, H. Kebir, I. Ifergan, P. J. Fabre, S. Terouz, M. Sabbagh, K. Wosik, L. Bourbonniere, M. Bernard, J. van Horssen, H. E. de Vries, F. Charron and A. Prat (2011). "The Hedgehog pathway promotes blood-brain barrier integrity and CNS immune quiescence." Science 334(6063): 1727-1731.
2. Andreu-Agullo, C., J. M. Morante-Redolat, A. C. Delgado and I. Farinas (2009). "Vascular niche factor PEDF modulates Notch-dependent stemness in the adult subependymal zone." Nat Neurosci 12(12): 1514-1523.
3. Artus, C., F. Glacial, K. Ganeshamoorthy, N. Ziegler, M. Godet, T. Guilbert, S. Liebner and P. O. Couraud (2014). "The Wnt/planar cell polarity signaling pathway contributes to the integrity of tight junctions in brain endothelial cells." J Cereb Blood Flow Metab 34(3): 433-440.
4. Bautch, V. L. and J. M. James (2009). "Neurovascular development: The beginning of a beautiful friendship." Cell Adh Migr 3(2): 199-204.
5. Bueno, D., M. Parvas, I. Hermelo and J. Garcia-Fernandez (2014). "Embryonic blood cerebrospinal fluid barrier formation and function." Front Neurosci 8: 343.
6. Daneman, R., D. Agalliu, L. Zhou, F. Kuhnert, C. J. Kuo and B. A. Barres (2009). "Wnt/beta catenin signaling is required for CNS, but not non-CNS, angiogenesis." Proc Natl Acad Sci U S A 106(2): 641-646.
7. Delgado, A. C., S. R. Ferron, D. Vicente, E. Porlan, A. Perez-Villalba, C. M. Trujillo, P. D'Ocon and I. Farinas (2014). "Endothelial NT-3 delivered by vasculature and CSF promotes quiescence of subependymal neural stem cells through nitric oxide induction." Neuron 83(3): 572-585.
8. Dziegielewska, K. M., G. W. Knott and N. R. Saunders (2000). "The nature and composition of the internal environment of the developing brain." Cell Mol Neurobiol 20(1): 41-56.
9. Falcao, A. M., F. Marques, A. Novais, N. Sousa, J. A. Palha and J. C. Sousa (2012). "The path from the choroid plexus to the subventricular zone: go with the flow!" Frontiers in Cellular Neuroscience 6.
10. Fuentealba, L. C., K. Obernier and A. Alvarez-Buylla (2012). "Adult neural stem cells bridge their niche." Cell Stem Cell 10(6): 698-708.
11. Goldman, S. A. and Z. Chen (2011). "Perivascular instruction of cell genesis and fate in the adult brain." Nature Neuroscience 14(11): 1382-1389.
12. Graciarena, M., V. Roca, P. Mathieu, A. M. Depino and F. J. Pitossi (2013). "Differential vulnerability of adult neurogenesis by adult and prenatal inflammation: role of TGF-beta1." Brain Behav Immun 34: 17-28.
13. Hatakeyama, J., Y. Wakamatsu, A. Nagafuchi, R. Kageyama, R. Shigemoto and K. Shimamura (2014). "Cadherin-based adhesions in the apical endfoot are required for active Notch signaling to control neurogenesis in vertebrates." Development 141(8): 1671-1682.
14. Hellstrom, M., L. K. Phng, J. J. Hofmann, E. Wallgard, L. Coultas, P. Lindblom, J. Alva, A. K. Nilsson, L. Karlsson, N. Gaiano, K. Yoon, J. Rossant, M. L. Iruela-Arispe, M. Kalen, H. Gerhardt and C. Betsholtz (2007). "Dll4 signalling through Notch1 regulates formation of tip cells during angiogenesis." Nature 445(7129): 776-780.
15. James, J. M., C. Gewolb and V. L. Bautch (2009). "Neurovascular development uses VEGF A signaling to regulate blood vessel ingression into the neural tube." Development 136(5): 833-841.
16. Javaherian, A. and A. Kriegstein (2009). "A stem cell niche for intermediate progenitor cells of the embryonic cortex." Cereb Cortex 19 Suppl 1: i70-77.
17. Johansson, P. A., S. Cappello and M. Gotz (2010). "Stem cells niches during development--lessons from the cerebral cortex." Curr Opin Neurobiol 20(4): 400-407.
18. Johansson, P. A., M. Irmler, D. Acampora, J. Beckers, A. Simeone and M. Gotz (2013). "The transcription factor Otx2 regulates choroid plexus development and function." Development 140(5): 1055-1066.
19. Johansson, P. A. (2014). "The choroid plexuses and their impact on developmental neurogenesis." Front Neurosci 8: 340.
20. Junghans, D., I. Hack, M. Frotscher, V. Taylor and R. Kemler (2005). "Beta-catenin mediated cell-adhesion is vital for embryonic forebrain development." Dev Dyn 233(2): 528-539.
21. Kokovay, E., S. Goderie, Y. Wang, S. Lotz, G. Lin, Y. Sun, B. Roysam, Q. Shen and S. Temple (2010). "Adult SVZ lineage cells home to and leave the vascular niche via differential responses to SDF1/CXCR4 signaling." Cell Stem Cell 7(2): 163-173.
22. Kokovay, E., Y. Wang, G. Kusek, R. Wurster, P. Lederman, N. Lowry, Q. Shen and S. Temple (2012). "VCAM1 is essential to maintain the structure of the SVZ niche and acts as an environmental sensor to regulate SVZ lineage progression." Cell Stem Cell 11(2): 220-230.
23. Komada, M., H. Saitsu, M. Kinboshi, T. Miura, K. Shiota and M. Ishibashi (2008). "Hedgehog signaling is involved in development of the neocortex." Development 135(16): 2717-2727.
24. Lehtinen, M. K., M. W. Zappaterra, X. Chen, Y. J. Yang, A. D. Hill, M. Lun, T. Maynard, D. Gonzalez, S. Kim, P. Ye, A. J. D'Ercole, E. T. Wong, A. S. LaMantia and C. A. Walsh (2011). "The cerebrospinal fluid provides a proliferative niche for neural progenitor cells." Neuron 69(5): 893-905.
25. Leventhal, C., S. Rafii, D. Rafii, A. Shahar and S. A. Goldman (1999). "Endothelial trophic support of neuronal production and recruitment from the adult mammalian subependyma." Mol Cell Neurosci 13(6): 450-464.
26. Li, L., K.M. Candelario, K. Thomas, R. Wang, K. Wright, A. Messier and L.A. Cunningham (2014). "Hypoxia inducible factor-1a (HIF-1a) is required for neural stem cell maintenance and vascular stability in the adult mouse SVZ." J. Neurosci. 34(50):16713-16719.
27. Liebner, S., M. Corada, T. Bangsow, J. Babbage, A. Taddei, C. J. Czupalla, M. Reis, A. Felici, H. Wolburg, M. Fruttiger, M. M. Taketo, H. von Melchner, K. H. Plate, H. Gerhardt and E. Dejana (2008). "Wnt/beta-catenin signaling controls development of the blood-brain barrier." J Cell Biol 183(3): 409-417.
28. Marques, F., J. C. Sousa, M. Correia-Neves, P. Oliveira, N. Sousa and J. A. Palha (2007). "The choroid plexus response to peripheral inflammatory stimulus." Neuroscience 144(2): 424-430.
29. McCarty, J. H., R. A. Monahan-Earley, L. F. Brown, M. Keller, H. Gerhardt, K. Rubin, M. Shani, H. F. Dvorak, H. Wolburg, B. L. Bader, A. M. Dvorak and R. O. Hynes (2002). "Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alphav integrins." Mol Cell Biol 22(21): 7667-7677.
30. Mirzadeh, Z., F. T. Merkle, M. Soriano-Navarro, J. M. Garcia-Verdugo and A. Alvarez-Buylla (2008). "Neural Stem Cells Confer Unique Pinwheel Architecture to the Ventricular Surface in Neurogenic Regions of the Adult Brain." Cell Stem Cell 3(3): 265-278.
31. Mollgard, K., Y. Balslev, B. Lauritzen and N. R. Saunders (1987). "Cell junctions and membrane specializations in the ventricular zone (germinal matrix) of the developing sheep brain: a CSF-brain barrier." J Neurocytol 16(4): 433-444.
32. Moreno-Lopez, B., C. Romero-Grimaldi, J. A. Noval, M. Murillo-Carretero, E. R. Matarredona and C. Estrada (2004). "Nitric oxide is a physiological inhibitor of neurogenesis in the adult mouse subventricular zone and olfactory bulb." J Neurosci 24(1): 85-95.
33. Nakagomi, N., T. Nakagomi, S. Kubo, A. Nakano-Doi, O. Saino, M. Takata, H. Yoshikawa, D. M. Stern, T. Matsuyama and A. Taguchi (2009). "Endothelial cells support survival, proliferation, and neuronal differentiation of transplanted adult ischemia-induced neural stem/progenitor cells after cerebral infarction." Stem Cells 27(9): 2185-2195.
34. Nakagomi, T., Z. Molnar, A. Nakano-Doi, A. Taguchi, O. Saino, S. Kubo, M. Clausen, H. Yoshikawa, N. Nakagomi and T. Matsuyama (2011). "Ischemia-induced neural stem/progenitor cells in the pia mater following cortical infarction." Stem Cells Dev 20(12): 2037-2051.
35. Nie, K., Z. Molnar and F. G. Szele (2010). "Proliferation but not migration is associated with blood vessels during development of the rostral migratory stream." Dev Neurosci 32(3): 163-172.
36. Ohira, K., T. Furuta, H. Hioki, K. C. Nakamura, E. Kuramoto, Y. Tanaka, N. Funatsu, K. Shimizu, T. Oishi, M. Hayashi, T. Miyakawa, T. Kaneko and S. Nakamura (2010). "Ischemia-induced neurogenesis of neocortical layer 1 progenitor cells." Nat Neurosci 13(2): 173-179.
37. Ottone, C., B. Krusche, A. Whitby, M. Clements, G. Quadrato, M. E. Pitulescu, R. H. Adams and S. Parrinello (2014). "Direct cell-cell contact with the vascular niche maintains quiescent neural stem cells." Nat Cell Biol 16(11): 1045-1056.
38. Palmer, T. D., A. R. Willhoite and F. H. Gage (2000). "Vascular niche for adult hippocampal neurogenesis." J Comp Neurol 425(4): 479-494.
39. Pluchino, S., L. Muzio, J. Imitola, M. Deleidi, C. Alfaro-Cervello, G. Salani, C. Porcheri, E. Brambilla, F. Cavasinni, A. Bergamaschi, J. M. Garcia-Verdugo, G. Comi, S. J. Khoury and G. Martino (2008). "Persistent inflammation alters the function of the endogenous brain stem cell compartment." Brain 131(Pt 10): 2564-2578.
40. Ramirez-Castillejo, C., F. Sanchez-Sanchez, C. Andreu-Agullo, S. R. Ferron, J. D. Aroca-Aguilar, P. Sanchez, H. Mira, J. Escribano and I. Farinas (2006). "Pigment epithelium derived factor is a niche signal for neural stem cell renewal." Nat Neurosci 9(3): 331-339.
41. Ruhrberg, C. and V. L. Bautch (2013). "Neurovascular development and links to disease." Cell Mol Life Sci 70(10): 1675-1684.
42. Shen, Q., S. K. Goderie, L. Jin, N. Karanth, Y. Sun, N. Abramova, P. Vincent, K. Pumiglia and S. Temple (2004). "Endothelial cells stimulate self-renewal and expand neurogenesis of neural stem cells." Science 304(5675): 1338-1340.
43. Shen, Q., Y. Wang, E. Kokovay, G. Lin, S.-M. Chuang, S. K. Goderie, B. Roysam and S. Temple (2008). "Adult SVZ Stem Cells Lie in a Vascular Niche: A Quantitative Analysis of Niche Cell-Cell Interactions." Cell Stem Cell 3(3): 289-300.
44. Shen, Q., Y. Wang, E. Kokovay, G. Lin, S. M. Chuang, S. K. Goderie, B. Roysam and S. Temple (2008). "Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions." Cell Stem Cell 3(3): 289-300.
45. Sockanathan, S. and N. Gaiano (2009). "Preview. Meninges Play a RAdical Role in Embryonic Neural Stem Cell Regulation." Cell Stem Cell 5(5): 455-456.
46. Stenman, J. M., J. Rajagopal, T. J. Carroll, M. Ishibashi, J. McMahon and A. P. McMahon (2008). "Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature." Science 322(5905): 1247-1250.
47. Stolp, H., A. Neuhaus, R. Sundramoorthi and Z. Molnar (2012). "The Long and the Short of it: Gene and Environment Interactions During Early Cortical Development and Consequences for Long-Term Neurological Disease." Front Psychiatry 3: 50.
48. Stolp, H. B., P. A. Johansson, M. D. Habgood, K. M. Dziegielewska, N. R. Saunders and C. J. Ek (2011). "Effects of neonatal systemic inflammation on blood-brain barrier permeability and behaviour in juvenile and adult rats." Cardiovasc Psychiatry Neurol 2011: 469046.
49. Stolp, H. B. (2013). "Neuropoietic cytokines in normal brain development and neurodevelopmental disorders." Mol Cell Neurosci 53: 63-68.
50. Stubbs, D., J. DeProto, K. Nie, C. Englund, I. Mahmud, R. Hevner and Z. Molnar (2009). "Neurovascular congruence during cerebral cortical development." Cereb Cortex 19 Suppl 1: i32-41.
51. Tavazoie, M., L. Van der Veken, V. Silva-Vargas, M. Louissaint, L. Colonna, B. Zaidi, J. M. Garcia-Verdugo and F. Doetsch (2008). "A Specialized Vascular Niche for Adult Neural Stem Cells." Cell Stem Cell 3(3): 279-288.
52. Tepavcevic, V., F. Lazarini, C. Alfaro-Cervello, C. Kerninon, K. Yoshikawa, J. M. Garcia-Verdugo, P. M. Lledo, B. Nait-Oumesmar and A. Baron-Van Evercooren (2011). "Inflammation-induced subventricular zone dysfunction leads to olfactory deficits in a targeted mouse model of multiple sclerosis." J Clin Invest 121(12): 4722-4734.
53. Tomita, S., M. Ueno, M. Sakamoto, Y. Kitahama, M. Ueki, N. Maekawa, H. Sakamoto, M. Gassmann, R. Kageyama, N. Ueda, F. J. Gonzalez and Y. Takahama (2003). "Defective brain development in mice lacking the Hif-1alpha gene in neural cells." Mol Cell Biol 23(19): 6739-6749.
54. Vasudevan, A., J. E. Long, J. E. Crandall, J. L. Rubenstein and P. G. Bhide (2008). "Compartment-specific transcription factors orchestrate angiogenesis gradients in the embryonic brain." Nat Neurosci 11(4): 429-439.
55. Villeda, S. A., J. Luo, K. I. Mosher, B. Zou, M. Britschgi, G. Bieri, T. M. Stan, N. Fainberg, Z. Ding, A. Eggel, K. M. Lucin, E. Czirr, J. S. Park, S. Couillard-Despres, L. Aigner, G. Li, E. R. Peskind, J. A. Kaye, J. F. Quinn, D. R. Galasko, X. S. Xie, T. A. Rando and T. Wyss-Coray (2011). "The ageing systemic milieu negatively regulates neurogenesis and cognitive function." Nature 477(7362): 90-94.
56. Virgintino, D., M. Errede, M. Rizzi, F. Girolamo, M. Strippoli, T. Walchli, D. Robertson, K. Frei and L. Roncali (2013). "The CXCL12/CXCR4/CXCR7 ligand-receptor system regulates neuro-glio-vascular interactions and vessel growth during human brain development." J Inherit Metab Dis 36(3): 455-466.