Therapeutic potential of adipose-derived SSEA-3-positive muse cells for treating diabetic skin ulcers

Stem Cells Translational Medicine

Volumn 4, Issue 2, 2015, Pages 146-155

  Kinoshita, Kahori ^a   Kuno, Shinichiro ^a   Ishimine, Hisako ^b   Aoi, Noriyuki ^a   Mineda, Kazuhide ^a   Kato, Harunosuke ^a   Doi, Kentaro ^a   Kanayama, Koji ^a   Feng, Jingwei ^a   Mashiko, Takanobu ^a   Kurisaki, Akira ^b   Yoshimura, Kotaro ^a  

^a UNIVERSITY OF TOKYO   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

Adipose; Adult stem cells; Cell culture; Hyaluronan; Ndothelial cell; Senchymal stem cells; Stem cell transplantation; Tissue regeneration

Indexed keywords

ENDOGLIN; NERVE GROWTH FACTOR BETA SUBUNIT; PHYCOERYTHRIN; PLATELET DERIVED GROWTH FACTOR; PROSTAGLANDIN E1; STAGE SPECIFIC EMBRYO ANTIGEN 3; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN; STAGE SPECIFIC EMBRYO ANTIGEN; STAGE-SPECIFIC EMBRYONIC ANTIGEN-3; TUMOR ANTIGEN;

ADIPOSE DERIVED STEM CELL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROLIFERATION; CELL SEPARATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MALE; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; MOUSE; MULTIPOTENT STEM CELL; NONHUMAN; SKIN ULCER; UPREGULATION; WOUND HEALING; ADIPOSE TISSUE; ADOLESCENT; ADULT; ANIMAL; BIOSYNTHESIS; DIABETES COMPLICATIONS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMA CELL; METABOLISM; PATHOLOGY; SCID MOUSE; XENOGRAFT;

MUS;

ADIPOSE TISSUE; ADOLESCENT; ADULT; ANIMALS; ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; DIABETES COMPLICATIONS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; FEMALE; HETEROGRAFTS; HUMANS; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STROMAL CELLS; MICE, SCID; MULTIPOTENT STEM CELLS; SKIN ULCER; STAGE-SPECIFIC EMBRYONIC ANTIGENS; WOUND HEALING;

EID: 84921746313     PISSN: 21576564     EISSN: 21576580     Source Type: Journal    
DOI: 10.5966/sctm.2014-0181     Document Type: Article

References (31)

1. Petersen BE, Bowen WC, Patrene KD et al. Bone marrow as a potential source of hepatic oval cells. Science 1999;284:1168-1170.
2. Harris RG, Herzog EL, BrusciaEMet al. Lack of a fusion requirement for development of bone marrow-derived epithelia. Science 2004; 305:90-93.
3. Ren G, Chen X, Dong F et al. Concise review: Mesenchymal stem cells and translational medicine: Emerging issues. STEM CELLS TRANSLATIONAL MEDICINE 2012;1:51-58.
4. Amoh Y, Li L, Katsuoka K et al. Multipotent nestin-positive, keratin-negative hair-follicle bulge stem cells can form neurons. Proc Natl Acad Sci USA 2005;102:5530-5534.
5. Toma JG, Akhavan M, Fernandes KJ et al. Isolation of multipotent adult stem cells from the dermis of mammalian skin. Nat Cell Biol 2001;3:778-784.
6. Kuroda Y, Kitada M, Wakao S et al. Unique multipotent cells in adult human mesenchymal cell populations. Proc Natl Acad Sci USA 2010; 107:8639-8643.
7. Yang Z, Liu J, Liu H et al. Isolation and characterization of SSEA3(+) stem cells derived from goat skin fibroblasts. Cell Reprogram 2013;15: 195-205.
8. Wakao S, Kitada M, Kuroda Y et al. Multilineage-differentiating stress-enduring (Muse) cells are a primary source of induced pluripotent stem cells in human fibroblasts. Proc Natl Acad Sci USA 2011;108:9875-9880.
9. Heneidi S, Simerman AA, Keller E et al. Awakened by cellular stress: Isolation and characterization of a novel population of pluripotent stem cells derived from human adipose tissue. PLoS One 2013;8:e64752.
10. Ogura F, Wakao S, Kuroda Y et al. Human adipose tissue possesses a unique population of pluripotent stem cells with nontumorigenic and low telomerase activities: Potential implications in regenerative medicine. Stem Cells Dev 2014;23:717- 728.
11. Yoshimura K, Shigeura T, Matsumoto D et al. Characterization of freshly isolated and cultured cells derived from the fatty and fluid portions of liposuction aspirates. J Cell Physiol 2006;208:64-76.
12. Tsuchiyama K, Wakao S, Kuroda Y et al. Functional melanocytes are readily reprogrammable from multilineage-differentiating stressenduring (muse) cells, distinct stem cells in human fibroblasts. J Invest Dermatol 2013; 133:2425-2435.
13. Galiano RD, Michaels J V., DobryanskyM et al. Quantitative and reproducible murine model of excisional wound healing. Wound Repair Regen 2004;12:485-492.
14. Tepper OM, Carr J, Allen RJ Jr et al. Decreased circulating progenitor cell number and failed mechanisms of stromal cell-derived factor-1alpha mediated bone marrow mobilization impair diabetic tissue repair. Diabetes 2010;59:1974-1983.
15. Schmidt RE, Dorsey DA, Beaudet LN et al. Non-obese diabetic mice rapidly develop dramatic sympathetic neuritic dystrophy: A new experimental model of diabetic autonomic neuropathy. Am J Pathol 2003;163: 2077-2091.
16. Lee RH, Seo MJ, Reger RL et al. Multipotent stromal cells from human marrow home to and promote repair of pancreatic islets and renal glomeruli in diabetic NOD/SCID mice. Proc Natl Acad Sci USA 2006;103:17438-17443.
17. Schmidt RE, Green KG, FengDet al. Erythropoietin and its carbamylated derivative prevent the development of experimental diabetic autonomic neuropathy in STZ-induced diabetic NOD-SCID mice. Exp Neurol 2008; 209:161-170.
18. Wakao S, Akashi H, Kushida Y et al. Muse cells, newly found non-tumorigenic pluripotent stem cells, reside in human mesenchymal tissues. Pathol Int 2014;64:1-9.
19. Kuroda Y, Wakao S, Kitada M et al. Isolation, culture and evaluation of multilineagedifferentiating stress-enduring (Muse) cells. Nat Protoc 2013;8:1391-1415.
20. Kablik J, Monheit GD, Yu L et al. Comparative physical properties of hyaluronic acid dermal fillers. Dermatol Surg 2009;35(suppl 1):302-312.
21. Itoi Y, Takatori M, Hyakusoku H et al. Comparison of readily available scaffolds for adipose tissue engineering using adipose-derived stem cells. J Plast Reconstr Aesthet Surg 2010; 63:858-864.
22. Açil Y, Zhang X, Nitsche T et al. Effects of different scaffolds on rat adipose tissue derived stroma cells. J Craniomaxillofac Surg 2014;42: 825-834.
23. Maxson S, Lopez EA, Yoo D et al. Concise review: Role of mesenchymal stem cells in wound repair. STEM CELLS TRANSLATIONAL MEDICINE 2012;1:142-149.
24. Eto H, Suga H, Inoueoi K et al. Adipose injury-associated factors mitigate hypoxia in ischemic tissues through activation of adipose stem/stromal cells and induction angiogenesis. Am J Pathol 2011;178:2322-2332.
25. Mooney DP, O'Reilly M, Gamelli RL. Tumor necrosis factor and wound healing. Ann Surg 1990;211:124-129.
26. Salomon GD, Kasid A, Cromack DT et al. The local effects of cachectin/tumor necrosis factor on wound healing. Ann Surg 1991;214: 175-180.
27. Shinozaki M, Okada Y, Kitano A et al. Impaired cutaneous wound healing with excess granulation tissue formation in TNFalpha-null mice. Arch Dermatol Res 2009;301:531-537.
28. Kono TM, Sims EK, Moss DR et al. Human adipose-derived stromal/stem cells protect against STZ-induced hyperglycemia: Analysis of hASC-derived paracrine effectors. STEM CELLS 2014;32:1831-1842.
29. Bassi ÊJ, Moraes-Vieira PM, Moreira-Sá CS et al. Immune regulatory properties of allogeneic adipose-derived mesenchymal stem cells in the treatment of experimental autoimmune diabetes. Diabetes 2012;61:2534- 2545.
30. Hausman GJ,Hausman DB. Search for the preadipocyte progenitor cell. J Clin Invest 2006; 116:3103-3106.
31. Eto H, Ishimine H, Kinoshita K et al. Characterization of human adipose tissue-resident hematopoietic cell populations reveals a novel macrophage subpopulation with CD34 expression and mesenchymal multipotency. Stem Cells Dev 2013;22:985-997.