Imaging endogenous opioid peptide release with [11C]carfentanil and [3H]diprenorphine: Influence of agonist-induced internalization

Journal of Cerebral Blood Flow and Metabolism

Volumn 34, Issue 10, 2014, Pages 1604-1612

  Quelch, Darren R ^a   Katsouri, Loukia ^a   Nutt, David J ^a   Parker, Christine A ^a,b   Tyacke, Robin J ^a  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

immunofluoresence; internalization; PET; 11C carfentanil; 3H diprenorphine; receptor

Indexed keywords

AMPHETAMINE; BETA ENDORPHIN; CARFENTANIL C 11; DELTA OPIATE RECEPTOR; DIPRENORPHINE H 3; DYNORPHIN A; DYNORPHIN B; ENDOMORPHIN 1; ENDOMORPHIN 2; KAPPA OPIATE RECEPTOR; LEUCINE ENKEPHALIN; METENKEPHALIN; METHADONE; MU OPIATE RECEPTOR; RADIOLIGAND; UNCLASSIFIED DRUG; CARFENTANIL; CENTRAL STIMULANT AGENT; DIPRENORPHINE; FENTANYL; NARCOTIC ANALGESIC AGENT; OPIATE PEPTIDE;

ADULT; AGONIST; AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING COMPETITION; BRAIN REGION; CELL FRACTIONATION; CELL LABELING; CELLULAR DISTRIBUTION; CEREBELLUM; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG BINDING SITE; DRUG PROTEIN BINDING; DRUG RECEPTOR BINDING; DRUG UPTAKE; ENDOSOME; HYPOTHALAMUS; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MALE; MOLECULAR IMAGING; NEUROTRANSMITTER RELEASE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; SUPERIOR COLLICULUS; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN; DRUG EFFECTS; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; POSITRON EMISSION TOMOGRAPHY; PROCEDURES; RADIOASSAY; SCINTISCANNING; SPRAGUE DAWLEY RAT;

AMPHETAMINE; ANALGESICS, OPIOID; ANIMALS; BRAIN; CENTRAL NERVOUS SYSTEM STIMULANTS; DIPRENORPHINE; FENTANYL; FLUORESCENT ANTIBODY TECHNIQUE; MALE; METHADONE; OPIOID PEPTIDES; POSITRON-EMISSION TOMOGRAPHY; RADIOLIGAND ASSAY; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84921711087     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2014.117     Document Type: Article

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