A life course approach to cardiovascular aging

Future Cardiology

Volumn 11, Issue 1, 2015, Pages 101-113

  Hardy, Rebecca ^a   Lawlor, Debbie A ^b   Kuh, Diana ^a  

^a MEDICAL RESEARCH COUNCIL   (United Kingdom)

^b UNIVERSITY OF BRISTOL   (United Kingdom)

Author keywords

Adiposity; birth weight; blood pressure; cardiovascular disease; cohort studies; glucose; life course; lipids; longitudinal modeling; social inequalities

Indexed keywords

GLUCOSE; LIPID; GLUCOSE BLOOD LEVEL;

AGING; BLOOD PRESSURE MEASUREMENT; BODY SIZE; CARDIOMETABOLIC RISK; CARDIOVASCULAR DISEASE; DISEASE COURSE; HEART MUSCLE METABOLISM; HUMAN; PREGNANCY; PRIORITY JOURNAL; PUBERTY; REVIEW; RISK FACTOR; ADOLESCENT; ADULT; ANALYSIS; BIRTH WEIGHT; BLOOD; BLOOD PRESSURE; BODY MASS; CHILD; FEMALE; GLUCOSE BLOOD LEVEL; HEALTH DISPARITY; MENOPAUSE; NEWBORN; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADOLESCENT; ADULT; AGING; BIRTH WEIGHT; BLOOD GLUCOSE; BLOOD PRESSURE; BODY MASS INDEX; CARDIOVASCULAR DISEASES; CHILD; FEMALE; HEALTH STATUS DISPARITIES; HUMANS; INFANT, NEWBORN; LIPIDS; MENOPAUSE; PREGNANCY; PUBERTY;

EID: 84921644387     PISSN: 14796678     EISSN: 17448298     Source Type: Journal    
DOI: 10.2217/fca.14.67     Document Type: Review

References (110)

1. Strong JP, Malcom GT, McMahan CA et al. Prevalance and extent of atherosclerosis in adolescents and young adults: implications for prevention from the Pathobiological Determinants of Atherosclerosis in Youth Study. JAMA 281(8), 727-735 (1999).
2. Palinski W, Napoli C. The fetal origins of atheroscelrosis: maternal hypercholesterolemia and choleserol-lowering or antioxidant treatment during pregnancy influence in utero programming and postnatal susceptibility to atherogenesis. FASEB J. 16(11), 1348-1360 (2002).
3. Goff DC, Lloyd-Jones DM, Bennett G et al. 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines. Circulation 129(25 Suppl. 2), S49-S73 (2014).
4. JBS3 Board. Joint British Societies' consensus recommendations for the prevention of cardiovascular disease (JBS3). Heart 100(Suppl. 2), ii1-ii67 (2014).
5. Expert Dyslipidemia Panel of the INternational Society Panel members. An International Atherosclerosis Society position paper: global recommendations for the management of dyslipidemia-full report. J. Clin. Lipidol. 8(1), 29-60 (2014).
6. Lloyd-Jones DM, Hong Y, Labarthe D et al. Defining and setting national goals for cardiovascular health promotion and disease reduction: the American Heart Association's strategic impact goal through 2020 and beyond. Circulation 121(4), 586-613 (2010).
7. Mishra GD, Ben-Shlomo Y, Kuh D. A life course approach to health behaviours: theory and methods. In: Handbook of Behavioural Medicine. Methods and Applications. Steptoe A (Ed.). Springer, NY, USA, 525-540 (2010).
8. Schooling M, Kuh D. A Life Course Appraoch to Women's Health. Kuh D, Hardy R (Eds). Oxford University Press, UK (2002).
9. A Life Course Approach to Chronic Disease Epidemiology: Tracing the Origins of Ill-Health from Early to Adult Life (2nd Edition). Kuh D, Ben-Shlomo Y (Eds). Oxford University Press, UK (2004).
10. Ben-Shlomo Y, Kuh D. A life course approach to chronic disease epidemiology: conceptual models, empirical challenges, and interdisciplinary perspectives. Int. J. Epidemiol. 31(2), 285-293 (2002).
11. Barker DJP. Mothers, Babies and Health in Later Life. (2nd Edition). Churchill Livingstone, UK (1998).
12. Kuh D, Smith GD. The life course and adult chronic disease: an historical perspective with particular reference to coronary heart disease. In: A Life Course Approach to Chronic Disease Epidemiology (2nd Edition). Kuh D, Ben-Shlomo Y (Eds). Oxford University Press, UK, 15-37 (2004).
13. Mishra GD, Nitsch D, Black S, De Stavola B, Kuh D, Hardy R. A structured approach to modelling the effects of binary exposure variables across the life course. Int. J. Epidemiol. 38(2), 528-537 (2009).
14. Hallqvist J, Lynch J, Bartley M, Lang T, Blane D. Can we disentangle life course processes of accumulation, critical period and social mobility? An analysis of disadvantaged socio-ecomomic positions and myocardial infarction in the Stockholm Heart Epidemiology Porgram. Soc. Sci. Med. 58(8), 1555-1562 (2004).
15. De Stavola B, Nitsch D, dos Santos Silva I et al. Statistical issues in life course epidemiology. Am. J. Epidemiol. 163(1), 84-96 (2006).
16. Wills A, Tilling K. Modelling repeat exposures: some examples from life course epidemiology. In: A Life Course Approach to Healthy Ageing. Kuh D, Cooper R, Hardy R, Richards M, Ben-Shlomo Y (Eds). Oxford University Press, UK, 91-108 (2014).
17. Smith GD. Epidemiology, epigenetics and the 'gloomy prospect': embracing randomness in population health research and practice. Int. J. Epidemiol. 40(3), 537-562 (2011).
18. Kuh D, Richards M, Cooper R, Hardy R, Ben-Shlomo Y. Life course epidemiology, ageing research and maturing cohort studies: a dynamic combination for understanding healthy ageing. In: A Life Course Approach to Healthy Ageing. Kuh D, Cooper R, Hardy R, Richards M, Ben-Shlomo Y (Eds). Oxford University Press, UK, 3-15 (2014).
19. Lawlor DA, Hardy R. A life course approach to cardiovascular and metabolic ageing. In: A Life Course Approach to Healthy Ageing. Kuh D, Cooper R, Hardy R, Richards M, Ben-Shlomo Y (Eds). Oxford University Press, UK, 146-161 (2014).
20. Smith GD, Ebrahim S. Mendelian randomization: prospects, potentials, and limitations. Int. J. Epidemiol. 33(1), 30-42 (2004).
21. Wills AK, Lawlor DA, Matthews F et al. Life course trajectories of systolic blood pressure using longitudinal data from UK cohorts. PLoS Med. 8(6), e1000440 (2011).
22. Pearson JD, Morrell CH, Brant IJ, Landis PK, Fleg JL. Age-associated changes in blood pressure in a clongitudinal study of healthy men and women. J. Gerontol. A Biol. Sci. Med. Sci. 52(3), M177-M183 (1997).
23. Franklin SS, Gustin W, Wong ND, Weber MA, Kannel WB, Levy D. Hemodynamic patterns of age-related changes in blood pressure. The Framingham Heart Study. Circulation 96(1), 308-315 (1997).
24. Labarthe DR, Dai S, Fulton JE, Harrist RB, Shah SM, Eissa MA. Systolic and fourt-and fifth-phase diastolic blood pressure from 8 to 18 years: Project HeartBeat! Am. J. Prev. Med. 37(1 Suppl.), S86-S89 (2009).
25. Reitz C, Luchsinger JA. Relation of blood pressure to cognitive impairment and dementia. Curr. Hypertens. Rev. 3(3), 166-176 (2007).
26. Carvalho JJ, Baruzzi PF, Howard PF et al. Blood pressure in four remote populations in the INTSERSALT study. Hypertension 14(3), 238-246 (1989).
27. Gurven M, Blackwell AD, Rodriguez DE, Stieglitz J, Kaplan H. Does blood pressure inevitably rise with age? Longitudinal evidecne among forager-horticulturists. Hypertension 60(1), 25-33 (2012).
28. Wills AK, Lawlor DA, Muniz-Terrera G et al. Population heterogeneity in trajectories of midlife blood pressure: the 1946 British Birth Cohort Study. J. Hypertens. 28(4), 679-686 (2012). •• Study defining latent classes of blood pressure change in midlife and relating them to early life risk factors and angina.
29. Allen NB, Siddique J, Wilkins JT et al. Blood pressure trajectories in early adulthood and subclinical atherosclerosis in middle age. JAMA 311(5), 490-497 (2014).
30. Jolliffe CJ, Janssen I. Distribution of lipoproteins by age and gender in adolescents. Circulation 114(10), 1056-1062 (2006).
31. Dai S, Fulton JE, Harrist RB, Grunbaum JA, Steffen LM, Labarthe DR. Blood lipids in children: age-related patterns and association with body-fat indices: Project HeartBeat! Am. J. Prev. Med. 37(Suppl. 1), S56-S64 (2009).
32. Singh GM, Danaei G, Pelizzari PM et al. The age associations of blood pressure, cholesterol, and glucose: analysis of health examinations surveys from international populations. Circulation 125(18), 2204-2211 (2012).
33. Mann D, Reynolds K, Smith D, Muntner P. Terns in statin use and low-density lipoprotein cholesterol levels among US adults: impact of the 2001 National Cholesterol Education Program guidelines. Ann. Pharmacol. 42, 1208-1215 (2008).
34. Jolliffe CJ, Janssen I. Development of age-specific adolescent metabolic syndrome criteria that are linked to the Adult Treatment Panel III and International Diabetes Federation criteria. J. Am. Coll. Cardiol. 49(8), 891-898 (2007).
35. Shimokata H, Muller DC, Fleg JL, Sorkin J, Ziemba AW, Andres R. Age as an independent determinant of glucose tolerance. Diabetes 40(1), 44-51 (1991).
36. Reaven G. Age and glucose intolerance: effect of fitness and fatness. Diabetes Care 26(2), 539-540 (2003).
37. Sattar N, Greer IA. Pregnancy complications and maternal cardiovascular risk: opportunities for intervention and screening? BMJ 325(7356), 157-160 (2002).
38. Rich-Edwards J. Reproductive health as a sentinel of chronic disease in women. Womens Health (Lond. Engl.) 5(2), 101-105 (2009).
39. Lakshman R, Forouhi NG, Sharp SJ et al. Early age at menarche associated with cardiovascular disease and mortality. J. Clin. Endocrinol. Metabol. 94(12), 4953-4960 (2009).
40. Hardy R, Kuh D, Whincup PH, Wadsworth MEJ. Age at puberty and adult blood pressure and body size in a British Birth Cohort Study. J. Hypertens. 24(1), 59-66 (2006).
41. Kivimaki M, Lawlor DA, Smith GD et al. Association of age at menarche with cardiovascular risk factors, vascular structure, and function in adulthood: the Cardiovascular Risk in Young Finns study. Am. J. Clin. Nutr. 87(6), 1876-1882 (2008).
42. Pierce M, Kuh D, Hardy R. Role of lifetime body mass index in the association bewteen age at puberty and adult lipids: findings from men and women in a British birth cohort. Ann. Epidemiol. 20(9), 676-682 (2010).
43. Lawlor DA, Emberson JR, Ebrahim S et al. Is the association between parity and coronary heart disease due to biological effects of pregnancy or adverse lifestyle risk factors associated with child-rearing? Findings from the British Women's Heart and Health Study and the British Regional Heart Study. Circulation 107(9), 1260-1264 (2003).
44. Hardy R, Lawlor DA, Black S, Wadsworth MEJ, Kuh D. Number of children and cardiovascular risk factors at age 53 years in men and women. BJOG 114(6), 721-730 (2007).
45. Harskamp RE, Zeeman GG. Preeclampsia: at risk for remote cardiovascular disease. Am. J. Med. Sci. 334(4), 291-295 (2007).
46. Bellamy L, Casas J-P, Hingorani AD, Williams DJ. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ 335(7627), 974 (2007).
47. Smith GD, Hyponnen E, Power C, Lawlor DA. Offspring birth weight and parental mortality: a prospective observational study and meta-analysis. Am. J. Epidemiol. 166(2), 160-169 (2007).
48. Smith GC, Pell JP, Walsh D. Pregnancy complications and maternal risk of ischaemic heart disease. Lancet 357(9273), 2002-2006 (2001).
49. Catov JM, Wu CS, Olsen J, Sutton-Tyrrell K, Li J, Nohr EA. Early or recurrent preterm birth and maternal cardiovascular disease risk. Ann. Epidemiol. 20(8), 604-609 (2010).
50. Lokkegaard E, Jovanovic Z, Heitmann BL, Keiding N, Ottesen B, Pedersen AT. The association between early menopause and risk of ischaemic heart disease: influence of hormone therapy. Maturitas 53(2), 226-233 (2006).
51. Matthews KA, Crawford SL, Chae CU et al. Are changes in cardiovascular disease risk factors in midlife women due to chronological aging or to the menopausal transition? J. Am. Coll. Cardiol. 54(25), 2366-2373 (2009).
52. Kok HS, van Asselt KM, vab der Schouw YT et al. Heart disease risk determines menopausal age rather than the reverse. J. Am. Coll. Cardiol. 47(10), 483-493 (2006).
53. Gast GC, Pop VJ, Samsioe GN et al. Vasomotor menopausal symptoms are associated with increased risk of coronary heart disease. Menopause 18(2), 146-151 (2011).
54. Thurston RC, Sutton-Tyrrell K, Everson-Rose SA, Hess R, Matthews KA. Hot flashes and subclinical cardiovascular disease: findings from the Study of Women's Health Across the Nation Heart Study. Circulation 118(12), 1234-1240 (2008).
55. Gast GC, Grobbee DE, Pop VJ et al. Menopausal complaints are associated with cardiovascular risk factors. Hypertension 51(6), 1492-1498 (2008).
56. Huxley R, Owen CG, Whincup PH et al. Is birth weight a risk factor for ischemic heart disease in later life? Am. J. Clin. Nutr. 85(5), 1250 (2007).
57. Whincup PH, Kaye SJ, Owen CG et al. Birth weight and risk of Type 2 diabetes: a systematic review. JAMA 300(24), 2886-2897 (2008).
58. Huxley R, Neil A, Collins R. Unravelling the fetal origins hypothesis: is there really an inverse association between birth weight and subsequent blood pressure? Lancet 360(9334), 659-665 (2002).
59. Huxley R, Owen CG, Whincup PH, Cook DG, Colman S, Collins R. Birth weight and subsequent cholesterol levels: exploration of the 'fetal origins' hypothesis. JAMA 292(22), 2755-2764 (2004).
60. Law CM, de Swiet M, Osmond C et al. Initiation of hypertension in utero and its amplification throughout life. BMJ 306(6868), 24-27 (1993).
61. Koupilova I, Leon DA, Lithell HO, Berglund L. Size at birth and hypertension in longitudinally followed 50-70 year-old men. Blood Press. 6(4), 223-228 (1997).
62. Hardy R, Kuh D, Langenberg C, Wadsworth MEJ. Birthwight, childhood social class, and change in adult blood pressure in the 1946 British birth cohort. Lancet 362(9391), 1178-1183 (2003).
63. Uiterwaal CS, Anthony S, Launer LJ et al. Birth weight, growth, and blood pressure: an annual follow-up of children aged 5 through 21 years. Hypertension 30(2 Pt 1), 267-271 (1997).
64. Williams S, Poulton R. Birth size, growth and blood pressure between ages of 7 and 26 years: failure to support the fetal origins hypotehsis. Am. J. Epidemiol. 155(9), 849-852 (2002).
65. Chen W, Srinivasan SR, Berensen GS. Amplification of the association between birthweight and blood pressure with age: the Bogalusa Heart Study. J. Hypertens. 28(10), 2046-2052 (2010).
66. Hardy R, Sovio U, King VJ et al. Birth weight and blood pressure in five European birth cohorts studies: an investigation of confounding factors. Eur. J. Pub. Health 16(1), 21-30 (2006).
67. Inskip HM, Godfrey KM, Robinson SM et al.; SWS Study Group. Cohort profile: the Southampton Women's Survey. Int. J. Epidemiol. 35(1), 42-48 (2006).
68. Cooper R, Atherton K, Power C. Gestational age and risk factors for cardiovascular disease: evidence from the 1958 British birth cohort followed to mid-life. Int. J. Epidemiol. 38(1), 235-244 (2008).
69. Keag O, Stock S, Norman J. Long-term childhood outcomes following caesarean section: systematic review and meta-analysis. Arch. Dis. Child. Fetal Neonatal Ed. 99(Suppl. 1), A8-A9 (2014).
70. Yeung EH, Druschel C. Cardiometabolic health of children conceived by assisted reproductive technologies. Fertil. Steril. 99(2), 318-326 (2013).
71. Park MH, Falconer C, Viner RM, Kinra S. The impact of childhood obesity on morbidity and mortality in adulthood: a systematic review. Obes. Rev. 13(11), 985-1000 (2012).
72. Owen CG, Whincup PH, Orfei L et al. Is body mass index before middle age related to coronary heart disease risk in later life? Evidence from observational studies. Int. J. Obes. (Lond.) 33(8), 866-877 (2009).
73. Baker JL, Olsen LW, Sorensen TIA. Childhood body-mass index and the risk of coronary heart disease in adulthood. N. Engl. J. Med. 357(23), 2329-2337 (2007).
74. Barker DJ, Osmond C, Forsen T, Kajantie E, Eriksson JG. Trajectories of growth among children who have coronary events as adults. N. Engl. J. Med. 353(17), 1802-1809 (2005).
75. Eriksson JG. Early growth and coronary heart disease and Type 2 diabetes: findings from the Helsinki Birth Cohort Study (HBCS). Am. J. Clin. Nutr. 94(6 Suppl.), 1799S-1802S (2011).
76. Must A, Jacques PF, Dallal GE, Bajema CJ, Dietz WH. Long-term morbidity and mortality of overweight adolescents. A follow-up of the Harvard Growth Study of 1922 to 1953. N. Engl. J. Med. 327(19), 1350-1355 (1992).
77. Lawlor DA, Benfield L, Logue J et al. Association between general and central adiposity in childhood, and change in these, with cardiovascular risk factors in adoleescence: prospective cohort study. BMJ 340, c6224 (2010).
78. Howe LD, Tilling K, Benfield L et al. Changes in ponderal index and body mass index across childhood and their associations with fat mass and cardiovascular risk factors at age 15. PLoS ONE 5(12), e15186 (2010).
79. Wills AK, Hardy RJ, Black S, Kuh DJ. Trajectories of overweight and body mass index in adulthood and blood pressure at age 53: the 1946 British Birth Cohort Study. J. Hypertens. 28(4), 679-686 (2010).
80. Juonala M, Magnussen CG, Berensen GS et al. Childhood adiposity, adult adiposity and cardiovascular risk factors. N. Engl. J. Med. 365(20), 1876-1885 (2011).
81. Kivimaki M, Smith GD, Timpson NJ et al. Lifetime body mass index and later atherosclerosis risk in young adults: examining causal links using mendelian randomization in the Cardiovascular Risk in Young Finns study. Eur. Heart J. 29(20), 2552-2560 (2008).
82. Nordestgaard BG, Palmer TM, Benn M et al. The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach. PLoS Med. 9(5), e100121 (2012).
83. Paajanen TA, Oksala NK, Kuukasjarvi P, Karhunen PJ. Short stature is associated with coronary heart disease: a systematic review of the literature and meta-analysis. Eur. Heart J. 31(14), 1802-1809 (2010).
84. Wadsworth MEJ, Hardy R, Paul AA, Marshall SF, Cole TJ. Leg and trunk length at 43 years in relation to childhood health, diet and family circumstances; evidence from the 1946 national birth cohort. Int. J. Epidemiol. 31(2), 383-390 (2002).
85. Whitley E, Gunnell D, Smith GD, Holly JM, Martin RM. Childhood circumstances and anthropometry: the Boyd Orr cohort. Ann. Hum. Biol. 35(5), 518-534 (2008).
86. Langenberg C, Hardy R, Kuh D, Wadsworth M. Influence of height, leg length and trunk length on pulse pressure. J. Hypertens. 21(3), 537-543 (2003).
87. Ferrie JE, Langenberg C, Shipley MJ, Marmot MG. Birth weight, components of height and coronary heart disease: evidence from the Whitehall II study. Int. J. Epidemiol. 35(6), 1532-1542 (2006).
88. Skidmore PML, Hardy RJ, Kuh DJ, Langenberg C, Wadsworth MEJ. LIfe course body size and lipid levels at 53 years in a British birth cohort. J. Epidemiol. Community Health 61(3), 215-220 (2007).
89. Lawlor DA, Ebrahim S, Smith GD. The associations between components of adult height and Type II diabetes and insulin resistance: British Women's Heart Study. Diabetologia 45(8), 1097-1106 (2002).
90. Gunnell D, Whitley E, Upton M, McConnachie A, Smith GD, Watt G. Associations of height, leg length, and lung function with cardiovascular risk factors in the Midspan Family Study. J. Epidemiol. Community Health 57(2), 141-146 (2003).
91. Langenberg C, Hardy R, Breeze E, Kuh D, Wadsworth MEJ. Influence of short stature on the change in pulse pressure, systolic and diastolic blood pressure from age 36 to 53 years: an analysis using multilevel models. Int. J. Epidemiol. 34(4), 905-913 (2005).
92. Johnson W, Kuh D, Tikhonoff V et al. Body mass index and height from infancy to adulthood and carotid intima-media thickness at 60 to 64 years in the 1946 British Birth Cohort Study. Arterioscler. Thromb. Vasc. Biol. 34, 654-660 (2014).
93. Galobardes B, Smith GD, Lynch JW. Systematic review of the influence of childhood socioeconomic circumstances on risk of cardiovascular disease in adulthood. Ann. Epidemiol. 16(2), 91-104 (2006).
94. Galobardes B, Lynch JW, Smith GD. Childhood socioeocnomic circumstances and cause-specific mortality in adulthood: systematic review and interpretation. Epidemiol. Rev. 26, 7-21 (2004).
95. Galobardes B, Lynch JW, Smith GD. Is the association between childhood socioeconomic circumstances and cause-specific mortality established? Update of a systematic review. J. Epidemiol. Community Health 62(5), 387-390 (2008).
96. Colhoun H, Hemingway H, Poulter N. Socio-economic status and blood pressure: an overview analysis. J. Hum. Hypertens. 12(2), 91-110 (1998).
97. Batty GD, Leon DA. Socio-economic position and coronary heart disease risk factors in children and young people. Evidence from the UK epidemiological studies. Eur. J. Pub. Health 12(4), 263-272 (2002).
98. Lawlor DA, Smith GD. Early life determinants of adult blood pressure. Curr. Opin. Nephrol. Hypertens. 14(3), 259-264 (2005).
99. Lawlor DA, Ebrahim S, Smith GD; British Women's Heart and Health Study. Socioeconomic position in childhood and adulthood and insulin resistance: cross sectional survey using data from British Women's Heart and Health Study. BMJ 325(7368), 805 (2002).
100. Lawlor DA, Smith GD, Ebrahim S. Association between childhood socioeconomic status and coronary heart disease risk among postmenopausal women: findings from the British Women's Heart and Health Study. Am. J. Pub. Health. 94(8), 1386-1392 (2004).
101. Murray ET, Mishra GD, Kuh D, Guralnik J, Black S, Hardy R. Life course models of socioeconomic position and cardiovascular risk factors: 1946 birth cohort. Ann. Epidemiol. 21(8), 589-597 (2011).
102. Langenberg C, Kuh D, Wadsworth MEJ, Brunner E, Hardy R. Social circumstances and education: life course origins of social inequalities in metabolic risk in a prospective national birth cohort. Am. J. Pub. Health. 96(12), 2216-2221 (2006).
103. McCarron P, Smith GD, Okasha M, McEwen J. Blood pressure in young adulthood and mortality from cardiovascular disease. Lancet 355(9213), 1430-1431 (2000).
104. Sundstrom J, Neovius M, Tynelius P, Rasmussen F. Association of blood pressure in late adolescence with subsequent mortality: cohort study of Swedish male conscripts. BMJ 342, d643 (2011).
105. Raitakari OT, Jounala M, Kahonen M et al. Cardiovascular risk factors in childhood and carotid artery intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns study. JAMA 290(17), 2277-2283 (2003).
106. Juonala M, Magnussen CG, Venn A et al. Influence of age on associations between childhood risk factors and carotid intima-media thickness in adulthood: the Cardiovascular Risk in Young Finns study, the Childhood Determinats of Adult Health study, the Bogalusa Heart Study, and the Muscatine Study for the International Childhood Cardiovascular Cohort (i3C) Consortium. Circulation 122(24), 1604-1611 (2010).
107. Li X, Li S, Ulusoy E, Chen W, Srinivasan SR, Berensen GS. Childhood adiposity as a predictor of cardiac mass in adulthood: the Bogalusa Heart Study. Circulation 110(22), 3488-3492 (2004).
108. Ference BA, Julius S, Mahajan N, Levy PD, Williams KA, Flack JM. Clinical effect of naturally random allocation to lower systolic blood pressire beginning before the development of hypertension. Hypertension 63(6), 1182-1188 (2014).
109. Allen N, Berry JD, Ning H, Van Horn L, Dyer A, Lloyd-Jones DM. Impact of blood pressure change during middle age on the remaining lifetime risk for cardiovascular disease: the Cardiovascular Lifetime Risk Pooling Project. Circulation 125(1), 37-44 (2012).
110. Ghosh AK, Hardy RJ, Francis DP et al. Midlife blood pressure change and left ventricular mass and remodelling in older age in the 1946 British Birth Cohort Study. Eur. Heart J. doi:10.1093/eurheartj/ehu389 (2014) (Epub ahead of print).