Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [11C]-PBR28

NeuroImage: Clinical

Volumn 7, Issue , 2015, Pages 409-414

  Zürcher, Nicole R ^a   Loggia, Marco L ^a   Lawson, Robert ^a   Chonde, Daniel B ^a   Izquierdo Garcia, David ^a   Yasek, Julia E ^a   Akeju, Oluwaseun ^a   Catana, Ciprian ^a   Rosen, Bruce R ^a   Cudkowicz, Merit E ^a   Hooker, Jacob M ^a   Atassi, Nazem ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Amyotrophic lateral sclerosis; Microglia; Motor cortex; Neuroinflammation; Positron emission tomography 11C PBR 28

Indexed keywords

PERIPHERAL BENZODIAZEPINE RECEPTOR 28 C 11; TRACER; UNCLASSIFIED DRUG; ACETAMIDE DERIVATIVE; CARBON; N-(2-METHOXYBENZYL)-N-(4-PHENOXYPYRIDIN-3-YL)ACETAMIDE; PYRIDINE DERIVATIVE; RADIOPHARMACEUTICAL AGENT;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BRAIN; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; FEMALE; GLIA; HUMAN; IN VIVO STUDY; MALE; MIDDLE AGED; MOTONEURON; MOTOR CORTEX; MOTOR PERFORMANCE; NERVOUS SYSTEM INFLAMMATION; NEUROIMAGING; NEUROPATHOLOGY; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENOTYPE; POSITRON EMISSION TOMOGRAPHY; PREDICTIVE VALUE; PRIMARY MOTOR CORTEX; PRIORITY JOURNAL; PYRAMIDAL TRACT; RATING SCALE; SCORING SYSTEM; VOXEL BASED MORPHOMETRY; COMPUTER ASSISTED DIAGNOSIS; PROCEDURES; SCINTISCANNING;

ACETAMIDES; ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; BRAIN; CARBON RADIOISOTOPES; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUROGLIA; POSITRON-EMISSION TOMOGRAPHY; PYRIDINES; RADIOGRAPHIC IMAGE INTERPRETATION, COMPUTER-ASSISTED; RADIOPHARMACEUTICALS;

EID: 84921640979     PISSN: None     EISSN: 22131582     Source Type: Journal    
DOI: 10.1016/j.nicl.2015.01.009     Document Type: Article

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