Disruptive mood dysregulation disorder: A new diagnostic approach to chronic irritability in youth

American Journal of Psychiatry

Volumn 171, Issue 9, 2014, Pages 918-924

  Roy, Amy Krain ^a   Lopes, Vasco ^a   Klein, Rachel G ^a  

^a FORDHAM UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMOXETINE; CLONIDINE; METHYLPHENIDATE; PLACEBO; RISPERIDONE; VALPROIC ACID; ANTICONVULSIVE AGENT; NEUROLEPTIC AGENT; TRANQUILIZER;

ANGER; ARTICLE; ATTENTION DEFICIT DISORDER; BIPOLAR DISORDER; CHILD; CHILD PARENT RELATION; CLINICAL CLASSIFICATION; COGNITIVE THERAPY; COPING BEHAVIOR; DIFFERENTIAL DIAGNOSIS; DISRUPTIVE MOOD DYSREGULATION DISORDER; HOSTILITY; HUMAN; INTERMITTENT EXPLOSIVE DISORDER; INTERPERSONAL COMMUNICATION; IRRITABILITY; MOOD DISORDER; OPPOSITIONAL DEFIANT DISORDER; PARENT COUNSELING; PRIORITY JOURNAL; PSYCHIATRIC DIAGNOSIS; PSYCHOSOCIAL CARE; RELIABILITY; SOCIAL INTERACTION; STRUCTURED INTERVIEW; THOUGHT DISORDER; VALIDITY; ATTENTION DEFICIT AND DISRUPTIVE BEHAVIOR DISORDERS; CASE REPORT; CHILD BEHAVIOR; CLASSIFICATION; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DRUG EFFECTS; FAMILY THERAPY; MOOD DISORDERS; PROCEDURES; PSYCHOLOGICAL RATING SCALE; PSYCHOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC); TREATMENT OUTCOME;

ANTICONVULSANTS; ANTIMANIC AGENTS; ANTIPSYCHOTIC AGENTS; ATTENTION DEFICIT AND DISRUPTIVE BEHAVIOR DISORDERS; CHILD; CHILD BEHAVIOR; DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; FAMILY THERAPY; HUMANS; IRRITABLE MOOD; MOOD DISORDERS; PSYCHIATRIC STATUS RATING SCALES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME;

EID: 84921627821     PISSN: 0002953X     EISSN: 15357228     Source Type: Journal    
DOI: 10.1176/appi.ajp.2014.13101301     Document Type: Article

References (30)

1. Safer DJ: Irritable mood and the Diagnostic and Statistical Manual of Mental Disorders. Child Adolesc Psychiatry Ment Health 2009; 3:35
2. Moreno C, Laje G, Blanco C, Jiang H, Schmidt AB, Olfson M: National trends in the outpatient diagnosis and treatment of bipolar disorder in youth. Arch Gen Psychiatry 2007; 64:1032-1039 (Pubitemid 47360848)
3. Thomas T, Stansifer L, Findling RL: Psychopharmacology of pediatric bipolar disorders in children and adolescents. Pediatr Clin North Am 2011; 58:173-187, xii
4. Research Units on Pediatric Psychopharmacology Autism Network: Risperidone treatment of autistic disorder: longer-term bene fits and blinded discontinuation after 6 months. Am J Psychiatry 2005; 162:1361-1369
5. Leibenluft E, Charney DS, Towbin KE, Bhangoo RK, Pine DS: Defining clinical phenotypes of juvenile mania. Am J Psychiatry 2003; 160:430-437 (Pubitemid 41094250)
6. Brotman MA, Kassem L, Reising MM, Guyer AE, Dickstein DP, Rich BA, Towbin KE, Pine DS, McMahon FJ, Leibenluft E: Parental diagnoses in youth with narrow phenotype bipolar disorder or severe mood dysregulation. Am J Psychiatry 2007; 164:1238-1241 (Pubitemid 47292413)
7. Rich BA, Schmajuk M, Perez-Edgar KE, Fox NA, Pine DS, Leibenluft E: Different psychophysiological and behavioral responses elicited by frustration in pediatric bipolar disorder and severe mood dysregulation. Am J Psychiatry 2007; 164:309-317
8. Brotman MA, Rich BA, Guyer AE, Lunsford JR, Horsey SE, Reising MM, Thomas LA, Fromm SJ, Towbin K, Pine DS, Leibenluft E: Amygdala activation during emotion processing of neutral faces in children with severe mood dysregulation versus ADHD or bipolar disorder. Am J Psychiatry 2010; 167:61-69
9. Brotman MA, Schmajuk M, Rich BA, Dickstein DP, Guyer AE, Costello EJ, Egger HL, Angold A, Pine DS, Leibenluft E: Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children. Biol Psychiatry 2006; 60:991-997 (Pubitemid 44739929)
10. Burke JD, Hipwell AE, Loeber R: Dimensions of oppositional defiant disorder as predictors of depression and conduct disorder in preadolescent girls. J Am Acad Child Adolesc Psychiatry 2010; 49:484-492
11. Stringaris A, Cohen P, Pine DS, Leibenluft E: Adult outcomes of youth irritability: a 20-year prospective community-based study. Am J Psychiatry 2009; 166:1048-1054
12. Stringaris A, Goodman R: Longitudinal outcome of youth oppositionality: irritable, headstrong, and hurtful behaviors have distinctive predictions. J Am Acad Child Adolesc Psychiatry 2009; 48:404-412
13. Roy AK, Klein RG, Angelosante A, Bar-Haim Y, Leibenluft E, Hulvershorn L, Dixon E, Dodds A, Spindel C: Clinical features of young children referred for impairing temper outbursts. J Child Adolesc Psychopharmacol 2013; 23:588-596
14. Copeland WE, Angold A, Costello EJ, Egger H: Prevalence, co-morbidity, and correlates of DSM-5 proposed disruptive mood dysregulation disorder. Am J Psychiatry 2013; 170:173-179
15. Regier DA, Narrow WE, Clarke DE, Kraemer HC, Kuramoto SJ, Kuhl EA, Kupfer DJ: DSM-5 field trials in the United States and Canada, part II: test-retest reliability of selected categorical diagnoses. Am J Psychiatry 2013; 170:59-70
16. Margulies DM, Weintraub S, Basile J, Grover PJ, Carlson GA: Will disruptive mood dysregulation disorder reduce false diagnosis of bipolar disorder in children? Bipolar Disord 2012; 14:488-496
17. Axelson D, Findling RL, Fristad MA, Kowatch RA, Youngstrom EA, Horwitz SM, Arnold LE, Frazier TW, Ryan N, Demeter C, Gill MK, Hauser-Harrington JC, Depew J, Kennedy SM, Gron BA, Rowles BM, Birmaher B: Examining the proposed disruptive mood dysregulation disorder diagnosis in children in the Longitudinal Assessment of Manic Symptoms study. J Clin Psychiatry 2012; 73:1342-1350
18. Scotto Rosato N, Correll CU, Pappadopulos E, Chait A, Crystal S, Jensen PS; Treatment of Maladaptive Aggressive in Youth Steering Committee: Treatment of maladaptive aggression in youth: CERT guidelines, II: treatments and ongoing management. Pediatrics 2012; 129:e1577-e1586
19. Waxmonsky JG, Wymbs FA, Pariseau ME, Belin PJ, Waschbusch DA, Babocsai L, Fabiano GA, Akinnusi OO, Haak JL, Pelham WE: A novel group therapy for children with ADHD and severe mood dysregulation. J Atten Disord 2013; 17:527-541
20. Connor DF, Glatt SJ, Lopez ID, Jackson D, Melloni RH Jr: Psychopharmacology and aggression, I: a meta-analysis of stimulant effects on overt/covert aggression-related behaviors in ADHD. J Am Acad Child Adolesc Psychiatry 2002; 41:253-261 (Pubitemid 38338146)
21. Pappadopulos E, Woolston S, Chait A, Perkins M, Connor DF, Jensen PS: Pharmacotherapy of aggression in children and adolescents: effi cacy and effect size. J Can Acad Child Adolesc Psychiatry 2006; 15:27-39
22. Klein RG, Abikoff H, Klass E, Ganeles D, Seese LM, Pollack S: Clinical efficacy of methylphenidate in conduct disorder with and without attention deficit hyperactivity disorder. Arch Gen Psychiatry 1997; 54:1073-1080 (Pubitemid 27524371)
23. Waxmonsky J, Pelham WE, Gnagy E, Cummings MR, O'Connor B, Majumdar A, Verley J, Hoffman MT, Massetti GA, Burrows-MacLean L, Fabiano GA, Waschbusch DA, Chacko A, Arnold FW, Walker KS, Garefino AC, Robb JA: The efficacy and tolerability of methylphenidate and behaviormodification in children with attention-deficit/hyperactivity disorder and severe mood dysregulation. J Child Adolesc Psychopharmacol 2008; 18:573-588
24. Hazell PL, Stuart JE: A randomized controlled trial of clonidine added to psychostimulant medication for hyperactive and aggressive children. J Am Acad Child Adolesc Psychiatry 2003; 42:886-894 (Pubitemid 44515836)
25. Connor DF, Barkley RA, Davis HT: A pilot study of methylphenidate, clonidine, or the combination in ADHD comorbid with aggressive oppositional defiant or conduct disorder. Clin Pediatr (Phila) 2000; 39:15-25 (Pubitemid 30044196)
26. Donovan SJ, Stewart JW, Nunes EV, Quitkin FM, Parides M, Daniel W, Susser E, Klein DF: Divalproex treatment for youth with explosive temper and mood lability: a double-blind, placebo-controlled crossover design. Am J Psychiatry 2000; 157:818-820 (Pubitemid 30249664)
27. Blader JC, Schooler NR, Jensen PS, Pliszka SR, Kafantaris V: Adjunctive divalproex versus placebo for children with ADHD and aggression refractory to stimulant monotherapy. Am J Psychiatry 2009; 166:1392-1401
28. Dickstein DP, Towbin KE, Van Der Veen JW, Rich BA, Brotman MA, Knopf L, Onelio L, Pine DS, Leibenluft E: Randomized double-blind placebo-controlled trial of lithium in youths with severe mood dysregulation. J Child Adolesc Psychopharmacol 2009; 19:61-73
29. Carlson GA, Potegal M, Margulies D, Basile J, Gutkovich Z: Liquid risperidone in the treatment of rages in psychiatrically hospitalized children with possible bipolar disorder. Bipolar Disord 2010; 12:205-212
30. Krieger FV, Pheula GF, Coelho R, Zeni T, Tramontina S, Zeni CP, Rohde LA: An open-label trial of risperidone in children and adolescents with severe mood dysregulation. J Child Adolesc Psychopharmacol 2011; 21:237-243