Intranasal dexmedetomidine in combination with patient-controlled sedation during upper gastrointestinal endoscopy: A randomised trial

Acta Anaesthesiologica Scandinavica

Volumn 59, Issue 2, 2015, Pages 215-223

  Cheung, C W ^a   Qiu, Q ^a   Liu, J ^b   Chu, K M ^a   Irwin, M G ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALFENTANIL; DEXMEDETOMIDINE; PLACEBO; PROPOFOL; SODIUM CHLORIDE; HYPNOTIC SEDATIVE AGENT; NARCOTIC ANALGESIC AGENT;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIZZINESS; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; GASTROINTESTINAL ENDOSCOPY; HEADACHE; HEART RATE; HUMAN; MALE; NAUSEA; OBSERVER ASSESSMENT OF ALERTNESS SCALE; PATIENT CONTROLLED SEDATION; PATIENT SATISFACTION; PERIOPERATIVE PERIOD; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; SEDATION; SEDATION SCALE; SYSTOLIC BLOOD PRESSURE; UPPER GASTROINTESTINAL TRACT; VITAL SIGN; CONSCIOUS SEDATION; INTRANASAL DRUG ADMINISTRATION; PATIENT CONTROLLED ANALGESIA; PROCEDURES;

ADMINISTRATION, INTRANASAL; ADULT; ALFENTANIL; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; CONSCIOUS SEDATION; DEXMEDETOMIDINE; DOUBLE-BLIND METHOD; ENDOSCOPY, GASTROINTESTINAL; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; PATIENT SATISFACTION; PROPOFOL; SODIUM CHLORIDE;

EID: 84921598620     PISSN: 00015172     EISSN: 13996576     Source Type: Journal    
DOI: 10.1111/aas.12445     Document Type: Article

References (33)

1. Cohen LB, Wecsler JS, Gaetano JN, Benson AA, Miller KM, Durkalski V, Aisenberg J,. Endoscopic sedation in the United States: results from a nationwide survey. Am J Gastroenterol 2006; 101: 967-974.
2. Faigel DO, Baron TH, Goldstein JL, Hirota WK, Jacobson BC, Johanson JF, Leighton JA, Mallery JS, Peterson KA, Waring JP, Fanelli RD, Wheeler-Harbaugh J, Standards Practice Committee ASGE. Guidelines for the use of deep sedation and anesthesia for GI endoscopy. Gastrointest Endosc 2002; 56: 613-617.
3. Aantaa R, Scheinin M,. Alpha 2-adrenergic agents in anaesthesia. Acta Anaesthesiol Scand 1993; 37: 433-448.
4. Barletta JF, Miedema SL, Wiseman D, Heiser JC, McAllen KJ,. Impact of dexmedetomidine on analgesic requirements in patients after cardiac surgery in a fast-track recovery room setting. Pharmacotherapy 2009; 29: 1427-1432.
5. Hall JE, Uhrich TD, Barney JA, Arain SR, Ebert TJ,. Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions. Anesth Analg 2000; 90: 699-705.
6. Hogue CW Jr., Talke P, Stein PK, Richardson C, Domitrovich PP, Sessler DI,. Autonomic nervous system responses during sedative infusions of dexmedetomidine. Anesthesiology 2002; 97: 592-598.
7. Okada H, Kurita T, Mochizuki T, Morita K, Sato S,. The cardioprotective effect of dexmedetomidine on global ischaemia in isolated rat hearts. Resuscitation 2007; 74: 538-545.
8. Taittonen MT, Kirvela OA, Aantaa R, Kanto JH,. Effect of clonidine and dexmedetomidine premedication on perioperative oxygen consumption and haemodynamic state. Br J Anaesth 1997; 78: 400-406.
9. Wijeysundera DN, Naik JS, Beattie WS,. Alpha-2 adrenergic agonists to prevent perioperative cardiovascular complications: a meta-analysis. Am J Med 2003; 114: 742-752.
10. Yuen VM, Hui TW, Irwin MG, Yao TJ, Wong GL, Yuen MK,. Optimal timing for the administration of intranasal dexmedetomidine for premedication in children. Anaesthesia 2010; 65: 922-929.
11. Cheung CW, Ng KF, Liu J, Yuen MY, Ho MH, Irwin MG,. Analgesic and sedative effects of intranasal dexmedetomidine in third molar surgery under local anaesthesia. Br J Anaesth 2011; 107: 430-437.
12. Zhang X, Bai X, Zhang Q, Wang X, Lu L,. The safety and efficacy of intranasal dexmedetomidine during electrochemotherapy for facial vascular malformation: a double-blind, randomized clinical trial. J Oral Maxillofac Surg 2013; 71: 1835-1842.
13. Chernik DA, Gillings D, Laine H, Hendler J, Silver JM, Davidson AB, Schwam EM, Siegel JL,. Validity and reliability of the Observer'sAssessment of Alertness/Sedation Scale: study with intravenous midazolam. J Clin Psychopharmacol 1990; 10: 244-251.
14. Lee DW, Chan AC, Wong SK, Li AC, Sze TS, Chung SC,. The safety, feasibility, and acceptability of patient-controlled sedation for colonoscopy: prospective study. Hong Kong Med J 2004; 10: 84-88.
15. Chung F,. Are discharge criteria changing? J Clin Anesth 1993; 5: 64S-68S.
16. Jalowiecki P, Rudner R, Gonciarz M, Kawecki P, Petelenz M, Dziurdzik P,. Sole use of dexmedetomidine has limited utility for conscious sedation during outpatient colonoscopy. Anesthesiology 2005; 103: 269-273.
17. Demiraran Y, Korkut E, Tamer A, Yorulmaz I, Kocaman B, Sezen G, Akcan Y,. The comparison of dexmedetomidine and midazolam used for sedation of patients during upper endoscopy: a prospective, randomized study. Can J Gastroenterol 2007; 21: 25-29.
18. Muller S, Borowics SM, Fortis EA, Stefani LC, Soares G, Maguilnik I, Breyer HP, Hidalgo MP, Caumo W,. Clinical efficacy of dexmedetomidine alone is less than propofol for conscious sedation during ERCP. Gastrointest Endosc 2008; 67: 651-659.
19. Sleigh J,. All hands on dex. Anaesthesia 2012; 67: 1193-1197.
20. Tsai CJ, Chu KS, Chen TI, Lu DV, Wang HM, Lu IC,. A comparison of the effectiveness of dexmedetomidine versus propofol target-controlled infusion for sedation during fibreoptic nasotracheal intubation. Anaesthesia 2010; 65: 254-259.
21. Turker S, Onur E, Ozer Y,. Nasal route and drug delivery systems. Pharm World Sci 2004; 26: 137-142.
22. Iirola T, Vilo S, Manner T, Aantaa R, Lahtinen M, Scheinin M, Olkkola KT,. Bioavailability of dexmedetomidine after intranasal administration. Eur J Clin Pharmacol 2011; 67: 825-831.
23. Yuen VM, Irwin MG, Hui TW, Yuen MK, Lee LH,. A double-blind, crossover assessment of the sedative and analgesic effects of intranasal dexmedetomidine. Anesth Analg 2007; 105: 374-380.
24. Lee DW, Chan AC, Sze TS, Ko CW, Poon CM, Chan KC, Sin KS, Chung SC,. Patient-controlled sedation versus intravenous sedation for colonoscopy in elderly patients: a prospective randomized controlled trial. Gastrointest Endosc 2002; 56: 629-632.
25. Roseveare C, Seavell C, Patel P, Criswell J, Kimble J, Jones C, Shepherd H,. Patient-controlled sedation and analgesia, using propofol and alfentanil, during colonoscopy: a prospective randomized controlled trial. Endoscopy 1998; 30: 768-773.
26. Kulling D, Fantin AC, Biro P, Bauerfeind P, Fried M,. Safer colonoscopy with patient-controlled analgesia and sedation with propofol and alfentanil. Gastrointest Endosc 2001; 54: 1-7.
27. Metzner J, Posner KL, Domino KB,. The risk and safety of anesthesia at remote locations: the US closed claims analysis. Curr Opin Anaesthesiol 2009; 22: 502-508.
28. Metzner J, Domino KB,. Risks of anesthesia or sedation outside the operating room: the role of the anesthesia care provider. Curr Opin Anaesthesiol 2010; 23: 523-531.
29. Mazanikov M, Udd M, Kylänpää L, Mustonen H, Lindström O, Halttunen J, Färkkilä M, Pöyhiä R,. Patient-controlled sedation for ERCP: a randomized double-blind comparison of alfentanil and remifentanil. Endoscopy 2012; 44: 487-492.
30. Bloor BC, Ward DS, Belleville JP, Maze M,. Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes. Anesthesiology 1992; 77: 1134-1142.
31. Jalonen J, Hynynen M, Kuitunen A, Heikkila H, Perttila J, Salmenpera M, Valtonen M, Aantaa R, Kallio A,. Dexmedetomidine as an anesthetic adjunct in coronary artery bypass grafting. Anesthesiology 1997; 86: 331-345.
32. Biccard BM, Goga S, de Beurs J,. Dexmedetomidine and cardiac protection for non-cardiac surgery: a meta-analysis of randomised controlled trials. Anaesthesia 2008; 63: 4-14.
33. Chumbley GM, Hall GM, Salmon P,. Patient-controlled analgesia: an assessment by 200 patients. Anaesthesia 1998; 53: 216-221.