CXCR4 receptor overexpression in mesenchymal stem cells facilitates treatment of acute lung injury in rats

Journal of Biological Chemistry

Volumn 290, Issue 4, 2015, Pages 1994-2006

  Yang, Jing Xian ^a   Zhang, Nan ^a,b   Wang, Han Wei ^c   Gao, Peng ^c   Yang, Qing Ping ^a   Wen, Qing Ping ^c  

^a LIAONING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b CHINA MEDICAL UNIVERSITY   (China)

^c DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; ENDOTHELIAL CELLS; FLOWCHARTING; RATS; STEM CELLS; TISSUE;

ACUTE LUNG INJURY; CHEMOKINE RECEPTORS; CURATIVE EFFECTS; LENTIVIRAL VECTOR; LIPOPOLYSACCHARIDES; MESENCHYMAL STEM CELL; THERAPEUTIC POTENTIALS; VASCULAR ENDOTHELIAL CELLS;

CELL CULTURE;

CHEMOKINE RECEPTOR CXCR4; LENTIVIRUS VECTOR; LIPOPOLYSACCHARIDE; CXCR4 PROTEIN, RAT; GREEN FLUORESCENT PROTEIN;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE MARROW; CELL DIFFERENTIATION; CELL MIGRATION; CELL PROLIFERATION; CELL RENEWAL; CHEMOTAXIS; DISEASE COURSE; IMMUNOMODULATION; IN VITRO STUDY; IN VIVO STUDY; LUNG ALVEOLUS; MALE; MESENCHYMAL STEM CELL; NEUTROPHIL COUNT; NONHUMAN; PARACRINE SIGNALING; PROTEIN EXPRESSION; RAT; VASCULAR ENDOTHELIUM; ANIMAL; BRONCHOALVEOLAR LAVAGE FLUID; CELL MEMBRANE; CELL MOTION; CHEMISTRY; CYTOLOGY; INFLAMMATION; LENTIVIRINAE; MESENCHYMAL STROMA CELL; METABOLISM; SIGNAL TRANSDUCTION;

RATTUS;

ACUTE LUNG INJURY; ANIMALS; BONE MARROW; BRONCHOALVEOLAR LAVAGE FLUID; CELL DIFFERENTIATION; CELL MEMBRANE; CELL MOVEMENT; CELL PROLIFERATION; CHEMOTAXIS; GREEN FLUORESCENT PROTEINS; INFLAMMATION; LENTIVIRUS; LIPOPOLYSACCHARIDES; MALE; MESENCHYMAL STROMAL CELLS; RATS; RECEPTORS, CXCR4; SIGNAL TRANSDUCTION;

EID: 84921506286     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.605063     Document Type: Article

References (53)

1. Dushianthan, A., Grocott, M. P., Postle, A. D., and Cusack, R. (2011) Acute respiratory distress syndrome and acute lung injury. Postgrad. Med. J. 87, 612-622
2. Matthay, M. A., and Zemans, R. L. (2011) The acute respiratory distress syndrome: pathogenesis and treatment. Annu. Rev. Pathol. 6, 147-163
3. Villar, J., Sulemanji, D., and Kacmarek, R. M. (2014) The acute respiratory distress syndrome: incidence and mortality, has it changed? Curr. Opin. Crit. Care 20, 3-9
4. Spieth, P. M., and Zhang, H. (2014) Pharmacological therapies for acute respiratory distress syndrome. Curr. Opin. Crit. Care 20, 113-121
5. Bosma, K. J., Taneja, R., and Lewis, J. F. (2010) Pharmacotherapy for prevention and treatment of acute respiratory distress syndrome: current and experimental approaches. Drugs 70, 1255-1282
6. (2000) Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N. Engl. J. Med. 342, 1301-1308
7. Keating, A. (2012) Mesenchymal stromal cells: new directions. Cell Stem. Cell 10, 709-716
8. Hayes, M., Curley, G., and Laffey, J. G. (2012) Mesenchymal stem cells: a promising therapy for acute respiratory distress syndrome. F1000 Med. Rep. 4, 2
9. Sensebé, L., Krampera, M., Schrezenmeier, H., Bourin, P., and Giordano, R. (2010) Mesenchymal stem cells for clinical application. Vox. Sang 98, 93-107
10. Griffin, M., Iqbal, S. A., and Bayat, A. (2011) Exploring the application of mesenchymal stem cells in bone repair and regeneration. J. Bone Joint Surg. Br. 93, 427-434
11. Dominici, M., Le Blanc, K., Mueller, I., Slaper-Cortenbach, I., Marini, F., Krause, D., Deans, R., Keating, A., Prockop, D. j., and Horwitz, E. (2006) Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8, 315-317
12. Gupta, N., Su, X., Popov, B., Lee, J. W., Serikov, V., and Matthay, M. A. (2007) Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice. J. Immunol. 179, 1855-1863
13. Kotton, D. N., Ma, B. Y., Cardoso, W. V., Sanderson, E. A., Summer, R. S., Williams, M. C., and Fine, A. (2001) Bone marrow-derived cells as progenitors of lung alveolar epithelium. Development 128, 5181-5188
14. Rojas, M., Xu, J., Woods, C. R., Mora, A. L., Spears, W., Roman, J., and Brigham, K. L. (2005) Bone marrow-derived mesenchymal stem cells in repair of the injured lung. Am. J. Respir. Cell Mol. Biol. 33, 145-152
15. Goodman, R. B., Strieter, R. M., Martin, D. P., Steinberg, K. P., Milberg, J. A., Maunder, R. J., Kunkel, S. L., Walz, A., Hudson, L. D., and Martin, T. R. (1996) Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 154, 602-611
16. Donnelly, S. C., Strieter, R. M., Kunkel, S. L., Walz, A., Robertson, C. R., Carter, D. C., Grant, I. S., Pollok, A. J., and Haslett, C. (1993) Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups. Lancet 341, 643-647
17. Petty, J. M., Sueblinvong, V., Lenox, C. C., Jones, C. C., Cosgrove, G. P., Cool, C. D., Rai, P. R., Brown, K. K., Weiss, D. J., Poynter, M. E., and Suratt, B. T. (2007) Pulmonary stromal-derived factor-1 expression and effect on neutrophil recruitment during acute lung injury. J. Immunol. 178, 8148-8157
18. Bleul, C. C., Farzan, M., Choe, H., Parolin, C., Clark-Lewis, I., Sodroski, J., and Springer, T. A. (1996) The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry. Nature 382, 829-833
19. Oberlin, E., Amara, A., Bachelerie, F., Bessia, C., Virelizier, J. L., Arenzana-Seisdedos, F., Schwartz, O., Heard, J. M., Clark-Lewis, I., Legler, D. F., Loetscher, M., Baggiolini, M., and Moser, B. (1996) The CXC chemokine SDF-1 is the ligand for LESTR/fusin and prevents infection by T-cell-lineadapted HIV-1. Nature 382, 833-835
20. Phillips, R. J., Burdick, M. D., Hong, K., Lutz, M. A., Murray, L. A., Xue, Y. Y., Belperio, J. A., Keane, M. P., and Strieter, R. M. (2004) Circulating fibrocytes traffic to the lungs in response to CXCL12 and mediate fibrosis. J. Clin. Invest. 114, 438-446
21. Honczarenko, M., Le, Y., Swierkowski, M., Ghiran, I., Glodek, A. M., and Silberstein, L. E. (2006) Human bone marrow stromal cells express a distinct set of biologically functional chemokine receptors. Stem Cells 24, 1030-1041
22. Wynn, R. F., Hart, C. A., Corradi-Perini, C., O'Neill, L., Evans, C. A., Wraith, J. E., Fairbairn, L. J., and Bellantuono, I. (2004) A small proportion of mesenchymal stem cells strongly expresses functionally active CXCR4 receptor capable of promoting migration to bone marrow. Blood 104, 2643-2645
23. Hu, Y., Cheng, P., Xue, Y. X., Liu, Y. H. (2012) Glioma cells promote the expression of vascular cell adhesion molecule-1 on bone marrow-derived mesenchymal stem cells: a possible mechanism for their tropism toward gliomas. J. Mol. Neurosci. 48, 127-135
24. Rüster, B., Göttig, S., Ludwig, R. J., Bistrian, R., Müller, S., Seifried, E., Gille, J., and Henschler, R. (2006) Mesenchymal stem cells display coordinated rolling and adhesion behavior on endothelial cells. Blood 108, 3938-3944
25. Yan, Y., Ding, X., Li, K., Ciric, B., Wu, S., Xu, H., Gran, B., Rostami, A., and Zhang, G. X. (2012) CNS-specific therapy for ongoing EAE by silencing IL-17 pathway in astrocytes. Mol. Ther. 20, 1338-1348
26. Du, Z., Wei, C., Yan, J., Han, B., Zhang, M., Peng, C., and Liu, Y. (2013) Mesenchymal stem cells overexpressing C-X-C chemokine receptor type 4 improve early liver regeneration of small-for-size liver grafts. Liver Transpl. 19, 215-225
27. Zhao, J., He, D., Su, Y., Berdyshev, E., Chun, J., Natarajan, V., and Zhao, Y. (2011) Lysophosphatidic acid receptor 1 modulates lipopolysaccharide-induced inflammation in alveolar epithelial cells and murine lungs. Am. J. Physiol. Lung Cell Mol. Physiol. 301, L547-L556
28. Yang, J., Jiang, Z., Fitzgerald, D. C., Ma, C., Yu, S., Li, H., Zhao, Z., Li, Y., Ciric, B., Curtis, M., Rostami, A., and Zhang, G. X. (2009) Adult neural stem cells expressing IL-10 confer potent immunomodulation and remyelination in experimental autoimmune encephalitis. J. Clin. Invest. 119, 3678-3691
29. Lee, J. W., Fang, X., Gupta, N., Serikov, V., and Matthay, M. A. (2009) Allogeneic human mesenchymal stem cells for treatment of E. coli endotoxin- induced acute lung injury in the ex vivo perfused human lung. Proc. Natl. Acad. Sci. U.S.A. 106, 16357-16362
30. Liang, Z. X., Sun, J. P., Wang, P., Tian, Q., Yang, Z., and Chen, L. A. (2011) Bone marrow-derived mesenchymal stem cells protect rats from endotoxin-induced acute lung injury. Chin. Med. J. 124, 2715-2722
31. Li, J., Li, D., Liu, X., Tang, S., and Wei, F. (2012) Human umbilical cord mesenchymal stem cells reduce systemic inflammation and attenuate LPS-induced acute lung injury in rats. J. Inflamm. (Lond) 9, 33
32. Tai, W. L., Dong, Z. X., Zhang, D. D., and Wang, D. H. (2012) Therapeutic effect of intravenous bone marrow-derived mesenchymal stem cell transplantation on early-stage LPS-induced acute lung injury in mice. Nan. Fang Yi Ke Da Xue Xue Bao. 32, 283-290
33. Curley, G. F., Hayes, M., Ansari, B., Shaw, G., Ryan, A., Barry, F., O'Brien, T., O'Toole, D., and Laffey, J. G. (2012) Mesenchymal stem cells enhance recovery and repair following ventilator-induced lung injury in the rat. Thorax 67, 496-501
34. Yang, J., Yan, Y., Ciric, B., Yu, S., Guan, Y., Xu, H., Rostami, A., and Zhang, G. X. (2010) Evaluation of bone marrow- and brain-derived neural stem cells in therapy of central nervous system autoimmunity. Am. J. Pathol. 177, 1989-2001
35. Yang, J., Yan, Y., Ma, C. G., Kang, T., Zhang, N., Gran, B., Xu, H., Li, K., Ciric, B., Zangaladze, A., Curtis, M., Rostami, A., and Zhang, G. X. (2012) Accelerated and enhanced effect of CCR5-transduced bone marrow neural stem cells on autoimmune encephalomyelitis. Acta Neuropathol. 124, 491-503
36. Scholzen, T., and Gerdes, J. (2000) The Ki-67 protein: from the known and the unknown. J. Cell. Physiol. 182, 311-322
37. Hariprashad, A., and Rizzolo, D. (2013) Acute respiratory distress syndrome: an overview for physician assistants. JAAPA 26, 23-28
38. Miller, A. C., Elamin, E. M., and Suffredini, A. F. (2014) Inhaled anticoagulation regimens for the treatment of smoke inhalation-associated acute lung injury: a systematic review. Crit. Care Med. 42, 413-419
39. Aggarwal, S., and Pittenger, M. F. (2005) Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood 105, 1815-1822
40. Bernardo, M. E., Locatelli, F., and Fibbe, W. E. (2009) Mesenchymal stromal cells. Ann. N.Y. Acad. Sci. 1176, 101-117
41. Schu, S., Nosov, M., O'Flynn, L., Shaw, G., Treacy, O., Barry, F., Murphy, M., O'Brien, T., and Ritter, T. (2012) Immunogenicity of allogeneic mesenchymal stem cells. J. Cell Mol. Med. 16, 2094-2103
42. Le Blanc, K., Tammik, C., Rosendahl, K., Zetterberg, E., and Ringdén, O. (2003) HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp. Hematol. 31, 890-896
43. Zhu, Y. G., Feng, X. M., Abbott, J., Fang, X. H., Hao, Q., Monsel, A., Qu, J. M., Matthay, M. A., and Lee, J. W. (2014) Human mesenchymal stem cell microvesicles for treatment of Escherichia coli endotoxin-induced acute lung injury in mice. Stem. Cells 32, 116-125
44. Inamdar, A. C., and Inamdar, A. A. (2013) Mesenchymal stem cell therapy in lung disorders: pathogenesis of lung diseases and mechanism of action of mesenchymal stem cell. Exp. Lung Res. 39, 315-327
45. Sordi, V., Malosio, M. L., Marchesi, F., Mercalli, A., Melzi, R., Giordano, T., Belmonte, N., Ferrari, G., Leone, B. E., Bertuzzi, F., Zerbini, G., Allavena, P., Bonifacio, E., and Piemonti, L. (2005) Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood 106, 419-427
46. Lapidot, T., Dar, A., and Kollet, O. (2005) How do stem cells find their way home? Blood 106, 1901-1910
47. Bullwinkel, J., Baron-Lühr, B., Lüdemann, A., Wohlenberg, C., Gerdes, J., and Scholzen, T. (2006) Ki-67 protein is associated with ribosomal RNA transcription in quiescent and proliferating cells. J. Cell. Physiol. 206, 624-635
48. Rahmanzadeh, R., Hüttmann, G., Gerdes, J., and Scholzen, T. (2007) Chromophore-assisted light inactivation of pKi-67 leads to inhibition of ribosomal RNA synthesis. Cell Prolif. 40, 422-430
49. 2+ channels. Stem. Cells 32, 2799-2810
50. Sung, S. Y., Liao, C. H., Wu, H. P., Hsiao, W. C., Wu, I. H., Jinpu, Yu, Lin S. H., and Hsieh, C. L. (2013) Loss of let-7 microRNA upregulates IL-6 in bone marrow-derived mesenchymal stem cells triggering a reactive stromal response to prostate cancer. PLoS ONE 8, e71637
51. Pati, S., Gerber, M. H., Menge, T. D., Wataha, K. A., Zhao, Y., Baumgartner, J. A., Zhao, J., Letourneau, P. A., Huby, M. P., Baer, L. A., Salsbury, J. R., Kozar, R. A., Wade, C. E., Walker, P. A., Dash, P. K., Cox, C. S., Jr., Doursout, M. F., and Holcomb, J. B. (2011) Bone marrow derived mesenchymal stem cells inhibit inflammation and preserve vascular endothelial integrity in the lungs after hemorrhagic shock. PLoS ONE 6, e25171
52. Clark-Raymond, A., Meresh, E., Hoppensteadt, D., Fareed, J., Sinacore, J., and Halaris, A. (2014) Vascular endothelial growth factor: a potential diagnostic biomarker for major depression. J. Psychiatr. Res. 59, 22-27
53. Zhang, P., Dong, L., Yan, K., Long, H., Yang, T. T., Dong, M. Q., Zhou, Y., Fan, Q. Y., and Ma, B. A. (2013) CXCR4-mediated osteosarcoma growth and pulmonary metastasis is promoted by mesenchymal stem cells through VEGF. Oncol. Rep. 30, 1753-1761