Bone marrow-derived mesenchymal stem cells protect rats from endotoxin-induced acute lung injury

Chinese Medical Journal

Volumn 124, Issue 17, 2011, Pages 2715-2722

  Liang, Zhi Xin ^a   Sun, Ji Ping ^b   Wang, Ping ^a   Tian, Qing ^a   Yang, Zhen ^a   Chen, Liang An ^a  

^a CHINESE PLA GENERAL HOSPITAL   (China)

^b JINAN MILITARY GENERAL HOSPITAL   (China)

Author keywords

Co culture; Lipopolysaccharide; Lung injury; Mesenchymal stem cell

Indexed keywords

CD34 ANTIGEN; CD45 ANTIGEN; ENDOTOXIN; GENOMIC DNA; HYDROXYPROLINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MYELOPEROXIDASE; THY 1 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LUNG INJURY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; BONE MARROW CELL; CONTROLLED STUDY; ENZYME ACTIVITY; EX VIVO STUDY; FEMALE; HISTOPATHOLOGY; IMMUNE RESPONSE; IMMUNOMODULATION; LUNG ALVEOLUS MACROPHAGE; LUNG LAVAGE; LUNG PROTECTION; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; NEUTROPHIL CHEMOTAXIS; NEUTROPHIL COUNT; NONHUMAN; PHENOTYPE; PROTECTION; PROTEIN CONTENT; RAT; SUPERNATANT; SURVIVAL RATE;

ACUTE LUNG INJURY; ANIMALS; BONE MARROW CELLS; CELLS, CULTURED; COCULTURE TECHNIQUES; ENDOTOXINS; FEMALE; LUNG; MACROPHAGES, ALVEOLAR; MALE; MESENCHYMAL STEM CELL TRANSPLANTATION; MESENCHYMAL STEM CELLS; PEROXIDASE; RANDOM ALLOCATION; RATS; RATS, WISTAR;

EID: 80052520341     PISSN: 03666999     EISSN: None     Source Type: Journal    
DOI: 10.3760/cma.j.issn.0366-6999.2011.17.027     Document Type: Article

References (29)

1. Ware LB, Matthay MA. The acute respiratory distress syndrome. N Engl J Med 2000; 342: 1334-1349.
2. Ma YF, Sheng L, Gu J, Zhang M, Jiang GY. Analysis of clinical risk factors associated with mortality of severely injured multiple trauma patients with acute lung injury. Chin Med J 2009; 122: 701-705.
3. Matthay MA, Zimmerman GA. Acute lung injury and the acute respiratory distress syndrome, four decades of inquiry into pahtogenesis and rational management. Am J Respir Cell Mol Biol 2005; 33: 319-327.
4. Tsushima K, King LS, Aggarwal NR, De Gorordo A, D'Alessio FR, Kubo K. Acute lung injury review. Intern Med 2009; 48: 621-630.
5. Montzka K, Heidenreich A. Application of mesenchymal stromal cells in urological diseases. BJU Int 2010; 105: 309-312.
6. Katritsis DG, Sotiropoulou PA, Karvouni E, Karabinos I, Korovesis S, Perez SA, et al. Transcoronary transplantation of autologous mesenchymalstem cells and endothelial progenitors into infarcted human myocardium. Catheter Cardiovasc Interv 2005; 65: 321-329.
7. Mazzini L, Fagioli F, Boccaletti R, Mareschi K, Oliveri G, Olivieri C, et al. Stem cell therapy in amyotrophic lateral sclerosis: a methodological approach in humans. Amyotroph Lateral Scler Other Motor Neuron Disord 2003; 4: 158-161.
8. Iyer SS, Rojas M. Anti-inflammatory effects of mesenchymal stem cells: novel concept for future therapies. Expert Opin Biol Ther 2008; 8: 569-581.
9. Abe S, Boyer C, Liu X, Wen FQ, Kobayashi T, Fang Q, et al. Cells derived from the circulation contribute to the repair of lung injury. Am J Respir Crit Care Med 2004; 170: 1158-1163.
10. Sekiya I, Larson BL, Smith JR, Pochampally R, Cui JG, Prockop DJ. Expansion of human adult stem cells from bone marrow stroma: conditions that maximize the yields of early progenitors and evaluate their quality. Stem Cells 2002; 20: 530-541.
11. An J, Beauchemin N, Albanese J, Abney TO, Sullivan AK. Use of a rat cDNA probe specific for the Y chromosome to detect male-derived cells. J Androl 1997; 18: 289-293.
12. Zhou GJ, Zhang H, Zhi SD, Jiang GP, Wang J, Zhang M, et al. Protective effect of raloxifene on lipopolysaccharide and acid-induced acute lung injury in rats. Acta Pharmacol Sin 2007; 28: 1585-1590.
13. Lu KW, William Taeusch H, Robertson B, Goerke J, Clements JA. Polymer-surfactant treatment of meconiuminduced acute lung injury. Am J Respir Crit Care Med 2000; 162: 623-628.
14. Faress JA, Nethery DE, Kern EF, Eisenberg R, Jacono FJ, Allen CL, et al. Bleomycin-induced pulmonary fibrosis is attenuated by a monoclonal antibody targeting HER2. J Appl Physiol 2007; 103: 2077-2083.
15. Han J, Li C, Liu H, Fen D, Hu W, Liu Y, et al. Inhibition of lipopolysaccharide-mediated rat alveolar macrophage activation in vitro by antiflammin-1. Cell Biol Int 2008; 32: 1108-1115.
16. Magaud JP, Sargent I, Clarke PJ, Ffrench M, Rimokh R, Mason DY. Double immunocytochemical labeling of cell and tissue samples with monoclonal anti-bromodeoxyuridine. J Histochem Cytochem 1989; 37: 1517-1527.
17. Chalfie M, Tu Y, Euskirchen G, Ward WW, Prasher DC. Green fluorescent protein as a marker for gene expression. Science 1994; 263: 802-805.
18. Battiwalla M, Hematti P. Mesenchymal stem cells in hematopoietic stem cell transplantation. Cytotherapy 2009; 11: 503-515.
19. Yamada M, Kubo H, Kobayashi S, Ishizawa K, Numasaki M, Ueda S, et al. Bone marrow-derived progenitor cells are important for lung repair after lipopolysaccharide-induced lung injury. J Immunol 2004; 172: 1266-1272.
20. Bosma KJ, Lewis JF. Emerging therapies for treatment of acute lung injury and acute respiratory distress syndrome. Expert Opin Emerg Drugs 2007; 12:461-477.
21. Chopra M, Reuben JS, Sharma AC. Acute lung injury:apoptosis and signaling mechanisms. Exp Biol Med (Maywood) 2009; 234: 361-371.
22. Cho SW, Sun HJ, Yang JY, Jung JY, An JH, Cho HY, et al. Transplantation of mesenchymal stem cells overexpressing RANK-Fc or CXCR4 prevents bone loss in ovariectomized mice. Mol Ther 2009; 17: 1979-1987.
23. Lagan AL, Melley DD, Evans TW, Quinlan GJ. Pathogenesis of the systemic inflammatory syndrome and acute lung injury: role of iron mobilization and decompartmentalization. Am J Physiol Lung Cell Mol Physiol 2008; 294: L161-L174.
24. Maniatis NA, Kotanidou A, Catravas JD, Orfanos SE. Endothelial pathomechanisms in acute lung injury. Vascul Pharmacol 2008; 49: 119-133.
25. Mukhopadhyay S, Hoidal JR, Mukherjee TK. Role of TNF alpha in pulmonary pathophysiology. Respir Res 2006; 7: 125.
26. Beyth S, Borovsky Z, Mevorach D, Liebergall M, Gazit Z, Aslan H, et al. Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness. Blood 2005; 105: 2214-2219.
27. Maus UA, Koay MA, Delbeck T, Mack M, Ermert M, Ermert L, et al. Role of resident alveolar macrophages in leukocyte traffic into the alveolar air space of intact mice. Am J Physiol Lung Cell Mol Physiol 2002; 282: L1245-L1252.
28. Liu Y, Zhang J, Zhao Z, Ling Y. Pro-apoptotic role of NF-kappaB pathway inhibition in lipopolysaccharidestimulated polymorphonuclear neutrophils. Chin Med J 2003; 116: 1257-1261.
29. Wu Y, Wang H, Zhang J, Ma X, Meng J, Li Y, et al. Adenosine deaminase that acts on RNA 1 p150 in alveolar macrophage is involved in LPS-induced lung injury. Shock 2009; 31: 410-415.