Subclinical infection and dosing in primary immunodeficiencies

Clinical and Experimental Immunology

Volumn 178, Issue S1, 2014, Pages 67-69

  Jolles, S ^a  

^a UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOGLOBULIN;

ARTICLE; ASYMPTOMATIC INFECTION; BACTERIAL PNEUMONIA; BRONCHIECTASIS; COMMON VARIABLE IMMUNODEFICIENCY; HAEMOPHILUS INFLUENZAE; HUMAN; HUMORAL IMMUNE DEFICIENCY; IMMUNE DEFICIENCY; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; INFECTION SENSITIVITY; MEMORY CELL; MORAXELLA CATARRHALIS; PHARYNGITIS; PRIORITY JOURNAL; RECURRENT INFECTION; RESPIRATORY TRACT INFECTION; SINUSITIS; STREPTOCOCCUS PNEUMONIAE; VIRAL UPPER RESPIRATORY TRACT INFECTION; VIRUS SHEDDING; IMMUNOLOGY; PASSIVE IMMUNIZATION; PROCEDURES; RESPIRATORY TRACT INFECTIONS;

ASYMPTOMATIC INFECTIONS; COMMON VARIABLE IMMUNODEFICIENCY; HUMANS; IMMUNIZATION, PASSIVE; IMMUNOGLOBULINS; RESPIRATORY TRACT INFECTIONS;

EID: 84921481274     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12516     Document Type: Article

References (17)

1. Cunningham-Rundles C, Bodian C. Common variable immunodeficiency: clinical and immunological features of 248 patients. Clin Immunol 1999; 92:34-48.
2. Jolles S. The variable in common variable immunodeficiency: a disease of complex phenotypes. J Allergy Clin Immunol Pract 2013; 1:545-556; quiz 57.
3. Resnick ES, Moshier EL, Godbold JH, Cunningham-Rundles C. Morbidity and mortality in common variable immune deficiency over 4 decades. Blood 2012; 119:1650-1657.
4. Chen Y, Stirling RG, Paul E, Hore-Lacy F, Thompson BR, Douglass JA. Longitudinal decline in lung function in patients with primary immunoglobulin deficiencies. J Allergy Clin Immunol 2011; 127:1414-1417.
5. Lucas M, Lee M, Lortan J, Lopez-Granados E, Misbah S, Chapel H. Infection outcomes in patients with common variable immunodeficiency disorders: relationship to immunoglobulin therapy over 22 years. J Allergy Clin Immunol 2010; 125:1354-1360 e4.
6. Chapel H, Lucas M, Lee M etal. Common variable immunodeficiency disorders: division into distinct clinical phenotypes. Blood 2008; 112:277-286.
7. Micol R, Kayal S, Mahlaoui N etal. Protective effect of IgM against colonization of the respiratory tract by nontypeable Haemophilus influenzae in patients with hypogammaglobulinemia. J Allergy Clin Immunol 2012; 129:770-777.
8. Orange JS, Grossman WJ, Navickis RJ, Wilkes MM. Impact of trough IgG on pneumonia incidence in primary immunodeficiency: a meta-analysis of clinical studies. Clin Immunol 2010; 137:21-30.
9. Orange JS, Belohradsky BH, Berger M etal. Evaluation of correlation between dose and clinical outcomes in subcutaneous immunoglobulin replacement therapy. Clin Exp Immunol 2012; 169:172-181.
10. Bonagura VR, Marchlewski R, Cox A, Rosenthal DW. Biologic IgG level in primary immunodeficiency disease: the IgG level that protects against recurrent infection. J Allergy Clin Immunol 2008; 122:210-212.
11. Bexon MBJ, Rojavin M, Berger M, Zenker O. Increased frequency of infections at the end of the IVIG dosing cycle: effect characterization from three phase III studies. American Academy of Allergy, Asthma and Immunology (AAAAI) Meeting 2012; Abstract 730.
12. Kainulainen L, Nikoskelainen J, Vuorinen T, Tevola K, Liippo K, Ruuskanen O. Viruses and bacteria in bronchial samples from patients with primary hypogammaglobulinemia. Am J Respir Crit Care Med 1999; 159:1199-1204.
13. Kainulainen L, Vuorinen T, Rantakokko-Jalava K, Osterback R, Ruuskanen O. Recurrent and persistent respiratory tract viral infections in patients with primary hypogammaglobulinemia. J Allergy Clin Immunol 2010; 126:120-126.
14. Kloepfer KM, Lee WM, Pappas TE etal. Detection of pathogenic bacteria during rhinovirus infection is associated with increased respiratory symptoms and asthma exacerbations. J Allergy Clin Immunol 2014; 133:1301-1307, 7 e1-3.
15. Peltola V, Waris M, Kainulainen L, Kero J, Ruuskanen O. Virus shedding after human rhinovirus infection in children, adults and patients with hypogammaglobulinaemia. Clin Microbiol Infect 2013; 19:E322-327.
16. Serra G, Milito C, Mitrevski M etal. Lung MRI as a possible alternative to CT scan for patients with primary immune deficiencies and increased radiosensitivity. Chest 2011; 140:1581-1589.
17. Ruuskanen O, Waris M, Kainulainen L. Treatment of persistent rhinovirus infection with pegylated interferon alpha2a and ribavirin in patients with hypogammaglobulinemia. Clin Infect Dis 2014; 58:1784-1786.