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Volumn 29, Issue 2, 2015, Pages 129-143

The transcription factor Nerfin-1 prevents reversion of neurons into neural stem cells

Author keywords

Cancer; Central nervous system; Dedifferentiation; Drosophila; Neuroblasts; Stem cells

Indexed keywords

MYC PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR NERFIN 1; UNCLASSIFIED DRUG; ZINC FINGER PROTEIN; DROSOPHILA PROTEIN; NERFIN-1 PROTEIN, DROSOPHILA;

EID: 84921463432     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.250282.114     Document Type: Article
Times cited : (30)

References (52)
  • 1
    • 77956281721 scopus 로고    scopus 로고
    • Live imaging of Drosophila imaginal disc development
    • Aldaz S, Escudero LM, Freeman M. 2010. Live imaging of Drosophila imaginal disc development. Proc Natl Acad Sci 107: 14217–14222.
    • (2010) Proc Natl Acad Sci , vol.107 , pp. 14217-14222
    • Aldaz, S.1    Escudero, L.M.2    Freeman, M.3
  • 2
    • 0037461751 scopus 로고    scopus 로고
    • A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis
    • Bello BC, Hirth F, Gould AP. 2003. A pulse of the Drosophila Hox protein Abdominal-A schedules the end of neural proliferation via neuroblast apoptosis. Neuron 37: 209–219.
    • (2003) Neuron , vol.37 , pp. 209-219
    • Bello, B.C.1    Hirth, F.2    Gould, A.P.3
  • 3
    • 33745485289 scopus 로고    scopus 로고
    • The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila
    • Bello B, Reichert H, Hirth F. 2006. The brain tumor gene negatively regulates neural progenitor cell proliferation in the larval central brain of Drosophila. Development 133: 2639–2648.
    • (2006) Development , vol.133 , pp. 2639-2648
    • Bello, B.1    Reichert, H.2    Hirth, F.3
  • 4
    • 40549128664 scopus 로고    scopus 로고
    • Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development
    • Bello BC, Izergina N, Caussinus E, Reichert H. 2008. Amplification of neural stem cell proliferation by intermediate progenitor cells in Drosophila brain development. Neural Dev 3: 5.
    • (2008) Neural Dev , vol.3
    • Bello, B.C.1    Izergina, N.2    Caussinus, E.3    Reichert, H.4
  • 6
    • 33646027006 scopus 로고    scopus 로고
    • Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells
    • Betschinger J, Mechtler K, Knoblich JA. 2006. Asymmetric segregation of the tumor suppressor brat regulates self-renewal in Drosophila neural stem cells. Cell 124: 1241–1253.
    • (2006) Cell , vol.124 , pp. 1241-1253
    • Betschinger, J.1    Mechtler, K.2    Knoblich, J.A.3
  • 7
    • 49149131084 scopus 로고    scopus 로고
    • Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cells
    • Boone JQ, Doe CQ. 2008. Identification of Drosophila type II neuroblast lineages containing transit amplifying ganglion mother cells. Dev Neurobiol 68: 1185–1195.
    • (2008) Dev Neurobiol , vol.68 , pp. 1185-1195
    • Boone, J.Q.1    Doe, C.Q.2
  • 8
    • 41649093071 scopus 로고    scopus 로고
    • The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila
    • Bowman SK, Rolland V, Betschinger J, Kinsey KA, Emery G, Knoblich JA. 2008. The tumor suppressors Brat and Numb regulate transit-amplifying neuroblast lineages in Drosophila. Dev Cell 14: 535–546.
    • (2008) Dev Cell , vol.14 , pp. 535-546
    • Bowman, S.K.1    Rolland, V.2    Betschinger, J.3    Kinsey, K.A.4    Emery, G.5    Knoblich, J.A.6
  • 9
    • 0030589725 scopus 로고    scopus 로고
    • Biparous: A novel bHLH gene expressed in neuronal and glial precursors in Drosophila
    • Bush A, Hiromi Y, Cole M. 1996. Biparous: a novel bHLH gene expressed in neuronal and glial precursors in Drosophila. Dev Biol 180: 759–772.
    • (1996) Dev Biol , vol.180 , pp. 759-772
    • Bush, A.1    Hiromi, Y.2    Cole, M.3
  • 10
    • 34548120890 scopus 로고    scopus 로고
    • Ol-insm1b, a SNAG family transcription factor involved in cell cycle arrest during medaka development
    • Candal E, Alunni A, Thermes V, Jamen F, Joly J-S, Bourrat F. 2007. Ol-insm1b, a SNAG family transcription factor involved in cell cycle arrest during medaka development. Dev Biol 309: 1–17.
    • (2007) Dev Biol , vol.309 , pp. 1-17
    • Candal, E.1    Alunni, A.2    Thermes, V.3    Jamen, F.4    Joly, J.-S.5    Bourrat, F.6
  • 11
    • 84884947984 scopus 로고    scopus 로고
    • Midlife crisis encodes a conserved zinc-finger protein required to maintain neuronal differentiation in Drosophila
    • Carney TD, Struck AJ, Doe CQ. 2013. Midlife crisis encodes a conserved zinc-finger protein required to maintain neuronal differentiation in Drosophila. Development 140: 4155–4164.
    • (2013) Development , vol.140 , pp. 4155-4164
    • Carney, T.D.1    Struck, A.J.2    Doe, C.Q.3
  • 12
    • 27144555447 scopus 로고    scopus 로고
    • Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster
    • Caussinus E, Gonzalez C. 2005. Induction of tumor growth by altered stem-cell asymmetric division in Drosophila melanogaster. Nat Genet 37: 1125–1129.
    • (2005) Nat Genet , vol.37 , pp. 1125-1129
    • Caussinus, E.1    Gonzalez, C.2
  • 14
    • 33748163462 scopus 로고    scopus 로고
    • Myc in model organisms: A view from the flyroom
    • de la Cova C, Johnston LA. 2006. Myc in model organisms: A view from the flyroom. Semin Cancer Biol 16: 303–312.
    • (2006) Semin Cancer Biol , vol.16 , pp. 303-312
    • De La Cova, C.1    Johnston, L.A.2
  • 15
    • 0025774706 scopus 로고
    • The prospero gene specifies cell fates in the Drosophila central nervous system
    • Doe CQ, Chu-LaGraff Q, Wright DM, Scott MP. 1991. The prospero gene specifies cell fates in the Drosophila central nervous system. Cell 65: 451–464.
    • (1991) Cell , vol.65 , pp. 451-464
    • Doe, C.Q.1    Chu-Lagraff, Q.2    Wright, D.M.3    Scott, M.P.4
  • 16
    • 53049106922 scopus 로고    scopus 로고
    • Insulinomaassociated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex
    • Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Pääbo S, Huttner WB. 2008. Insulinomaassociated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron 60: 40–55.
    • (2008) Neuron , vol.60 , pp. 40-55
    • Farkas, L.M.1    Haffner, C.2    Giger, T.3    Khaitovich, P.4    Nowick, K.5    Birchmeier, C.6    Pääbo, S.7    Huttner, W.B.8
  • 17
    • 84879886243 scopus 로고    scopus 로고
    • Insulinomaassociated 1a (Insma) is required for photoreceptor differentiation in the zebrafish retina
    • Forbes-Osborne MA, Wilson SG, Morris AC. 2013. Insulinomaassociated 1a (Insma) is required for photoreceptor differentiation in the zebrafish retina. Dev Biol 380: 157–171.
    • (2013) Dev Biol , vol.380 , pp. 157-171
    • Forbes-Osborne, M.A.1    Wilson, S.G.2    Morris, A.C.3
  • 19
    • 84879395049 scopus 로고    scopus 로고
    • FACS purification of Drosophila larval neuroblasts for nextgeneration sequencing
    • Harzer H, Berger C, Conder R, Schmauss G, Knoblich JA. 2013. FACS purification of Drosophila larval neuroblasts for nextgeneration sequencing. Nat Protoc 8: 1088–1099.
    • (2013) Nat Protoc , vol.8 , pp. 1088-1099
    • Harzer, H.1    Berger, C.2    Conder, R.3    Schmauss, G.4    Knoblich, J.A.5
  • 20
    • 0036742659 scopus 로고    scopus 로고
    • Inhibition of cellular growth and proliferation by dTOR overexpression in Drosophila
    • Hennig KM, Neufeld TP. 2002. Inhibition of cellular growth and proliferation by dTOR overexpression in Drosophila. Genesis 34: 107–110.
    • (2002) Genesis , vol.34 , pp. 107-110
    • Hennig, K.M.1    Neufeld, T.P.2
  • 21
    • 84868545441 scopus 로고    scopus 로고
    • Drosophila neuroblasts: A model for stem cell biology
    • Homem CCF, Knoblich JA. 2012. Drosophila neuroblasts: A model for stem cell biology. Development 139: 4297–4310.
    • (2012) Development , vol.139 , pp. 4297-4310
    • Homem, C.1    Knoblich, J.A.2
  • 22
    • 84892550276 scopus 로고    scopus 로고
    • Long-term live cell imaging and automated 4D analysis of Drosophila neuroblast lineages
    • Homem CCF, Reichardt I, Berger C, Lendl T, Knoblich JA. 2013. Long-term live cell imaging and automated 4D analysis of Drosophila neuroblast lineages. PLoS ONE 8: e79588.
    • (2013) Plos ONE , vol.8
    • Homem, C.1    Reichardt, I.2    Berger, C.3    Lendl, T.4    Knoblich, J.A.5
  • 23
    • 84908432541 scopus 로고    scopus 로고
    • Ecdysone and mediator change energy metabolism to terminate proliferationin Drosophila neural stem cells
    • Homem CCF, Steinmann V, Burkard TR, Jais A, Esterbauer H, Knoblich JA. 2014. Ecdysone and mediator change energy metabolism to terminate proliferationin Drosophila neural stem cells. Cell 158: 874–888.
    • (2014) Cell , vol.158 , pp. 874-888
    • Homem, C.1    Steinmann, V.2    Burkard, T.R.3    Jais, A.4    Esterbauer, H.5    Knoblich, J.A.6
  • 27
    • 84876996918 scopus 로고    scopus 로고
    • TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
    • Kim D, Pertea G, Trapnell C, Pimentel H, Kelley R, Salzberg SL. 2013. TopHat2: Accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions. Genome Biol 14: R36.
    • (2013) Genome Biol , vol.14 , pp. R36
    • Kim, D.1    Pertea, G.2    Trapnell, C.3    Pimentel, H.4    Kelley, R.5    Salzberg, S.L.6
  • 28
    • 11144251131 scopus 로고    scopus 로고
    • Nerfin-1 is required for early axon guidance decisions in the developing Drosophila CNS
    • Kuzin A, Brody T, Moore AW, Odenwald WF. 2005. Nerfin-1 is required for early axon guidance decisions in the developing Drosophila CNS. Dev Biol 277: 347–365.
    • (2005) Dev Biol , vol.277 , pp. 347-365
    • Kuzin, A.1    Brody, T.2    Moore, A.W.3    Odenwald, W.F.4
  • 29
    • 34548834180 scopus 로고    scopus 로고
    • The Drosophila nerfin-1 mRNA requires multiple microRNAs to regulate its spatial and temporal translation dynamics in the developing nervous system
    • Kuzin A, Kundu M, Brody T, Odenwald WF. 2007. The Drosophila nerfin-1 mRNA requires multiple microRNAs to regulate its spatial and temporal translation dynamics in the developing nervous system. Dev Biol 310: 35–43.
    • (2007) Dev Biol , vol.310 , pp. 35-43
    • Kuzin, A.1    Kundu, M.2    Brody, T.3    Odenwald, W.F.4
  • 30
    • 84896735766 scopus 로고    scopus 로고
    • Voom: Precision weights unlock linear model analysis tools for RNA-seq read counts
    • Law CW, Chen Y, Shi W, Smyth GK. 2014. Voom: Precision weights unlock linear model analysis tools for RNA-seq read counts. Genome Biol 15: R29.
    • (2014) Genome Biol , vol.15 , pp. R29
    • Law, C.W.1    Chen, Y.2    Shi, W.3    Smyth, G.K.4
  • 31
    • 34247869955 scopus 로고    scopus 로고
    • Discrete functions of rictor and raptor in cell growth regulation in Drosophila
    • Lee G, Chung J. 2007. Discrete functions of rictor and raptor in cell growth regulation in Drosophila. Biochem Biophys Res Commun 357: 1154–1159.
    • (2007) Biochem Biophys Res Commun , vol.357 , pp. 1154-1159
    • Lee, G.1    Chung, J.2
  • 32
    • 0035341376 scopus 로고    scopus 로고
    • Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development
    • Lee T, Luo L. 2001. Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development. Trends Neurosci 24: 251–254.
    • (2001) Trends Neurosci , vol.24 , pp. 251-254
    • Lee, T.1    Luo, L.2
  • 33
    • 33845702193 scopus 로고    scopus 로고
    • Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation
    • Lee CY, Andersen RO, Cabernard C, Manning L, Tran KD, Lanskey MJ, Bashirullah A, Doe CQ. 2006a. Drosophila Aurora-A kinase inhibits neuroblast self-renewal by regulating aPKC/Numb cortical polarity and spindle orientation. Genes Dev 20: 3464–3474.
    • (2006) Genes Dev , vol.20 , pp. 3464-3474
    • Lee, C.Y.1    Ersen, R.O.2    Cabernard, C.3    Manning, L.4    Tran, K.D.5    Lanskey, M.J.6    Bashirullah, A.7    Doe, C.Q.8
  • 34
    • 33645525794 scopus 로고    scopus 로고
    • Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal
    • Lee CY, Wilkinson BD, Siegrist SE, Wharton RP, Doe CQ. 2006b. Brat is a Miranda cargo protein that promotes neuronal differentiation and inhibits neuroblast self-renewal. Dev Cell 10: 441–449.
    • (2006) Dev Cell , vol.10 , pp. 441-449
    • Lee, C.Y.1    Wilkinson, B.D.2    Siegrist, S.E.3    Wharton, R.P.4    Doe, C.Q.5
  • 35
    • 33745556537 scopus 로고    scopus 로고
    • INSM1 functions as a transcriptional repressor of the neuroD/b2 gene through the recruitment of cyclin D1 and histone deacetylases
    • Liu W-D, Wang H-W, Muguira M, Breslin MB, Lan MS. 2006. INSM1 functions as a transcriptional repressor of the neuroD/b2 gene through the recruitment of cyclin D1 and histone deacetylases. Biochem J 397: 169–177.
    • (2006) Biochem J , vol.397 , pp. 169-177
    • Liu, W.-D.1    Wang, H.-W.2    Muguira, M.3    Breslin, M.B.4    Lan, M.S.5
  • 36
    • 43949139294 scopus 로고    scopus 로고
    • Temporal transcription factors and their targets schedule the end of neural proliferation in Drosophila
    • Maurange C, Cheng L, Gould AP. 2008. Temporal transcription factors and their targets schedule the end of neural proliferation in Drosophila. Cell 133: 891–902.
    • (2008) Cell , vol.133 , pp. 891-902
    • Maurange, C.1    Cheng, L.2    Gould, A.P.3
  • 37
    • 0027947609 scopus 로고
    • Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells
    • Rhyu MS, Jan LY, Jan YN. 1994. Asymmetric distribution of numb protein during division of the sensory organ precursor cell confers distinct fates to daughter cells. Cell 76: 477–491.
    • (1994) Cell , vol.76 , pp. 477-491
    • Rhyu, M.S.1    Jan, L.Y.2    Jan, Y.N.3
  • 38
    • 79952190285 scopus 로고    scopus 로고
    • The bHLH factor deadpan is a direct target of Notch signaling and regulates neuroblast self-renewal in Drosophila
    • San-Juan BP, Baonza A. 2011. The bHLH factor deadpan is a direct target of Notch signaling and regulates neuroblast self-renewal in Drosophila. Dev Biol 352: 70–82.
    • (2011) Dev Biol , vol.352 , pp. 70-82
    • San-Juan, B.P.1    Baonza, A.2
  • 40
    • 4544341015 scopus 로고    scopus 로고
    • Linear models and empirical Bayes methods for assessing differential expression in microarray experiments
    • Smyth GK. 2004. Linear models and empirical Bayes methods for assessing differential expression in microarray experiments. Stat Appl Genet Mol Biol 3: 1–25.
    • (2004) Stat Appl Genet Mol Biol , vol.3 , pp. 1-25
    • Smyth, G.K.1
  • 42
    • 84155197399 scopus 로고    scopus 로고
    • Regulation of cell growth by Notch signaling and its differential requirement in normal vs. Tumor-forming stem cells in Drosophila
    • Song Y, Lu B. 2011. Regulation of cell growth by Notch signaling and its differential requirement in normal vs. tumor-forming stem cells in Drosophila. Genes Dev 25: 2644–2658.
    • (2011) Genes Dev , vol.25 , pp. 2644-2658
    • Song, Y.1    Lu, B.2
  • 43
    • 84897394717 scopus 로고    scopus 로고
    • Dedifferentiation of neurons precedes tumor formation in Lola mutants
    • Southall TD, Davidson CM, Miller C, Carr A, Brand AH. 2014. Dedifferentiation of neurons precedes tumor formation in Lola mutants. Dev Cell 28: 685–696.
    • (2014) Dev Cell , vol.28 , pp. 685-696
    • Southall, T.D.1    Davidson, C.M.2    Miller, C.3    Carr, A.4    Brand, A.H.5
  • 44
    • 0028803382 scopus 로고
    • The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila
    • Spana EP, Doe CQ. 1995. The prospero transcription factor is asymmetrically localized to the cell cortex during neuroblast mitosis in Drosophila. Development 121: 3187–3195.
    • (1995) Development , vol.121 , pp. 3187-3195
    • Spana, E.P.1    Doe, C.Q.2
  • 45
    • 0342409276 scopus 로고    scopus 로고
    • Nerfin-1 and -2, novel Drosophila Zn-finger transcription factor genes expressed in the developing nervous system
    • Stivers C, Brody T, Kuzin A, Odenwald WF. 2000. Nerfin-1 and -2, novel Drosophila Zn-finger transcription factor genes expressed in the developing nervous system. Mech Dev 97: 205–210.
    • (2000) Mech Dev , vol.97 , pp. 205-210
    • Stivers, C.1    Brody, T.2    Kuzin, A.3    Odenwald, W.F.4
  • 46
    • 33747195353 scopus 로고    scopus 로고
    • Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
    • Takahashi K, Yamanaka S. 2006. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663–676.
    • (2006) Cell , vol.126 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 47
    • 0025721048 scopus 로고
    • Prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila
    • Vaessin H, Grell E, Wolff E, Bier E, Jan LY, Jan YN. 1991. prospero is expressed in neuronal precursors and encodes a nuclear protein that is involved in the control of axonal outgrowth in Drosophila. Cell 67: 941–953.
    • (1991) Cell , vol.67 , pp. 941-953
    • Vaessin, H.1    Grell, E.2    Wolff, E.3    Bier, E.4    Jan, L.Y.5    Jan, Y.N.6
  • 48
    • 33845704687 scopus 로고    scopus 로고
    • Aurora-A acts as a tumor suppressor and regulates selfrenewal of Drosophila neuroblasts
    • Wang H, Somers GW, Bashirullah A, Heberlein U, Yu F, Chia W. 2006. Aurora-A acts as a tumor suppressor and regulates selfrenewal of Drosophila neuroblasts. Genes Dev 20: 3453–3463.
    • (2006) Genes Dev , vol.20 , pp. 3453-3463
    • Wang, H.1    Somers, G.W.2    Bashirullah, A.3    Heberlein, U.4    Yu, F.5    Chia, W.6
  • 49
    • 74049157004 scopus 로고    scopus 로고
    • DFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila
    • Weng M, Golden KL, Lee C-Y. 2010. dFezf/Earmuff maintains the restricted developmental potential of intermediate neural progenitors in Drosophila. Dev Cell 18: 126–135.
    • (2010) Dev Cell , vol.18 , pp. 126-135
    • Weng, M.1    Golden, K.L.2    Lee, C.-Y.3
  • 50
    • 0035868643 scopus 로고    scopus 로고
    • Inhibition of touch cell fate by egl-44 and egl-46 in C. Elegans
    • Wu J, Duggan A, Chalfie M. 2001. Inhibition of touch cell fate by egl-44 and egl-46 in C. elegans. Genes Dev 15: 789–802.
    • (2001) Genes Dev , vol.15 , pp. 789-802
    • Wu, J.1    Duggan, A.2    Chalfie, M.3
  • 51
    • 84866788234 scopus 로고    scopus 로고
    • Klumpfuss distinguishes stem cells from progenitor cells during asymmetric neuroblast division
    • Xiao Q, Komori H, Lee C-Y. 2012. klumpfuss distinguishes stem cells from progenitor cells during asymmetric neuroblast division. Development 139: 2670–2680.
    • (2012) Development , vol.139 , pp. 2670-2680
    • Xiao, Q.1    Komori, H.2    Lee, C.-Y.3
  • 52
    • 84857925453 scopus 로고    scopus 로고
    • BHLH-O proteins are crucial for Drosophila neuroblast self-renewal and mediate Notch-induced overproliferation
    • Zacharioudaki E, Magadi SS, Delidakis C. 2012. bHLH-O proteins are crucial for Drosophila neuroblast self-renewal and mediate Notch-induced overproliferation. Development 139: 1258–1269.
    • (2012) Development , vol.139 , pp. 1258-1269
    • Zacharioudaki, E.1    Magadi, S.S.2    Delidakis, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.