Association of severe obstructive sleep apnea and elevated blood pressure despite antihypertensive medication use

Journal of Clinical Sleep Medicine

Volumn 10, Issue 8, 2014, Pages 835-843

  Walia, Harneet K ^a   Li, Hong ^a   Rueschman, Michael ^b   Bhatt, Deepak L ^b   Patel, Sanjay R ^b,c   Quan, Stuart F ^b   Gottlieb, Daniel J ^b,c   Punjabi, Naresh M ^d   Redline, Susan ^b,c   Mehra, Reena ^a  

^a CASE WESTERN RESERVE UNIVERSITY   (United States)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Blood pressure; Cardiovascular disease; Sleep apnea

Indexed keywords

ANTIHYPERTENSIVE AGENT; DIURETIC AGENT;

ADULT; AGE DISTRIBUTION; AGED; ARTICLE; BLOOD PRESSURE MONITORING; BODY MASS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL EXAMINATION; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE ASSOCIATION; DISEASE SEVERITY; ELEVATED BLOOD PRESSURE; FEMALE; HUMAN; HYPOTHESIS; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; RACE DIFFERENCE; RANDOMIZED CONTROLLED TRIAL; SEX DIFFERENCE; SLEEP DISORDERED BREATHING; SMOKING; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; COMPLICATION; DRUG EFFECTS; HYPERTENSION; MIDDLE AGED; RISK FACTOR; SEVERITY OF ILLNESS INDEX; TREATMENT FAILURE;

AGED; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; CARDIOVASCULAR DISEASES; FEMALE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; RISK FACTORS; SEVERITY OF ILLNESS INDEX; SLEEP APNEA, OBSTRUCTIVE; TREATMENT FAILURE;

EID: 84921440872     PISSN: 15509389     EISSN: 15509397     Source Type: Journal    
DOI: 10.5664/jcsm.3946     Document Type: Article

References (36)

1. Calhoun DA, Harding SM. Sleep and hypertension. Chest 2010;138:434-43.
2. Dempsey JA. Sleep apnea causes daytime hypertension. J Clin Invest 1997;99:1-2.
3. Fletcher EC Hypertension in patients with sleep apnoea, a combined effect? Thorax 2000;55:726-8.
4. Kohler M, Stradling JR. Mechanisms of vascular damage in obstructive sleep apnea. Nat Rev Cardiol 2010;7:677-85.
5. Morgan BJ, Dempsey JA, Pegelow DF, et al. Blood pressure perturbations caused by subclinical sleep-disordered breathing. Sleep 1998;21:737-46.
6. Okabe S, Hida W, Kikuchi Y, et al. Role of hypoxia on increased blood pressure in patients with obstructive sleep apnoea. Thorax 1995;50:28-34.
7. Nieto FJ, Young TB, Lind BK, et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in a large community-based study. Sleep Heart Health Study. JAMA 2000;283:1829-36.
8. Vasan RS, Larson MG, Leip EP, Kannel WB, Levy D. Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study. Lancet 2001;358:1682-6.
9. Vasan RS, Larson MG, Leip EP, et al. Impact of high-normal blood pressure on the risk of cardiovascular disease. N Engl J Med 2001;345:1291-7.
10. Kshirsagar AV, Carpenter M, Bang H, Wyatt SB, Colindres RE. Blood pressure usually considered normal is associated with an elevated risk of cardiovascular disease. Am J Med 2006;119:133-41.
11. Sairenchi T, Iso H, Irie F, et al. Age-specific relationship between blood pressure and the risk of total and cardiovascular mortality in Japanese men and women. Hypertens Res 2005;28:901-9.
12. Dudenbostel T, Calhoun DA. Resistant hypertension, obstructive sleep apnoea and aldosterone. J Hum Hypertens 2012;26:281-7.
13. Martinez-Garcia MA, Gomez-Aldaravi R, Gil-Martinez T, Soler-Cataluna JJ, Bernacer-Alpera B, Roman-Sanchez P. [Sleep-disordered breathing in patients with difficult-to-control hypertension]. Arch Bronconeumol 2006;42:14-20.
14. Hong Y, LaBresh KA. Overview of the American Heart Association "Get with the Guidelines" programs: coronary heart disease, stroke, and heart failure. Crit Pathw Cardiol 2006;5:179-86.
15. Mancia G, Fagard R. Guidelines for the management of hypertension and target organ damage: reply. J Hypertens 2013;31:2464-5.
16. Dingli K, Coleman EL, Vennelle M, et al. Evaluation of a portable device for diagnosing the sleep apnoea/hypopnoea syndrome. Eur Respir J 2003;21:253-9.
17. Iber C, Ancoli-Israel S, Chesson A, Quan SF. The AASM manual for the scoring of sleep and associated events: rules, terminology and technical specifications. 1st ed. Westchester, IL: American Academy of Sleep Medicine, 2007.
18. Chobanian AV, Bakris GL, Black HR, et al. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003;289:2560-72.
19. Huang Y, Wang S, Cai X, et al. Prehypertension and incidence of cardiovascular disease: a meta-analysis. BMC Med 2013;11:177.
20. Lonati L, Cuspidi C, Sampieri L, et al. Ultrasonographic evaluation of cardiac and vascular changes in young borderline hypertensives. Cardiology 1993;83:298-303.
21. Sipahi I, Tuzcu EM, Schoenhagen P, et al. Effects of normal, pre-hypertensive, and hypertensive blood pressure levels on progression of coronary atherosclerosis. J Am Coll Cardiol 2006;48:833-8.
22. Izzo JL Jr., Levy D, Black HR. Clinical Advisory Statement. Importance of systolic blood pressure in older Americans. Hypertension 2000;35:1021-4.
23. Martinez-Garcia MA, Capote F, Campos-Rodriguez F, et al. Effect of CPAP on blood pressure in patients with obstructive sleep apnea and resistant hypertension: the HIPARCO randomized clinical trial. JAMA 2013;310:2407-15.
24. Butler J, Kalogeropoulos AP, Georgiopoulou VV, et al. Systolic blood pressure and incident heart failure in the elderly. The Cardiovascular Health Study and the Health, Ageing and Body Composition Study. Heart 2011;97:1304-11.
25. Staessen JA, Thijs L, Fagard R, et al. Predicting cardiovascular risk using conventional vs ambulatory blood pressure in older patients with systolic hypertension. Systolic Hypertension in Europe Trial Investigators. JAMA 1999;282:539-46.
26. Kostis JB, Davis BR, Cutler J, et al. Prevention of heart failure by antihypertensive drug treatment in older persons with isolated systolic hypertension. SHEP Cooperative Research Group. JAMA 1997;278:212-6.
27. Ogden LG, He J, Lydick E, Whelton PK. Long-term absolute benefit of lowering blood pressure in hypertensive patients according to the JNC VI risk stratification. Hypertension 2000;35:539-43.
28. Lavie L Obstructive sleep apnoea syndrome-an oxidative stress disorder. Sleep Med Rev 2003;7:35-51.
29. Pratt-Ubunama MN, Nishizaka MK, Boedefeld RL, Cofield SS, Harding SM, Calhoun DA. Plasma aldosterone is related to severity of obstructive sleep apnea in subjects with resistant hypertension. Chest 2007;131:453-9.
30. Gonzaga CC, Gaddam KK, Ahmed MI, et al. Severity of obstructive sleep apnea is related to aldosterone status in subjects with resistant hypertension. J Clin Sleep Med 2010;6:363-8.
31. Pimenta E, Stowasser M, Gordon RD, et al. Increased dietary sodium is related to severity of obstructive sleep apnea in patients with resistant hypertension and hyperaldosteronism. Chest 2013;143:978-83.
32. Somers VK, Dyken ME, Clary MP, Abboud FM. Sympathetic neural mechanisms in obstructive sleep apnea. J Clin Invest 1995;96:1897-904.
33. Pepin JL, Tamisier R, Barone-Rochette G, Launois SH, Levy P, Baguet JP. Comparison of continuous positive airway pressure and valsartan in hypertensive patients with sleep apnea. Am J Respir Crit Care Med 2010;182:954-60.
34. Pickering TG, Shimbo D, Haas D. Ambulatory blood-pressure monitoring. N Engl J Med 2006;354:2368-74.
35. Verdecchia P, Angeli F, Cavallini C. Ambulatory blood pressure for cardiovascular risk stratification. Circulation 2007;115:2091-3.
36. McManus RJ, Caulfield M, Williams B. NICE hypertension guideline 2011: evidence based evolution. BMJ 2012;344:e181.