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Volumn 23, Issue 3, 2015, Pages 564-578

Discovery and SAR study of c-Met kinase inhibitors bearing an 3-amino-benzo[d]isoxazole or 3-aminoindazole scaffold

Author keywords

3 Amino benzo d isoxazole; 3 Aminoindazole; c Met kinase; Inhibitor; Non small cell lung cancer

Indexed keywords

3 AMINO BENZO[D]ISOXAZOLE; 3 AMINOINDAZOLE; AGENTS AFFECTING METABOLISM; ANTIMITOTIC AGENT; ENZYME INHIBITOR; FUSED CARBON NITROGEN HETEROCYCLE; ISOXAZOLE; N [3 [(3 AMINOBENZO[D]ISOXAZOL 4 YL)OXY]PHENYL] N (4 FLUOROPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL) 3 FLUOROPHENYL] N (4 FLUOROPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N (2,4 DIFLUOROPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N (3 CHLORO 4 FLUOROPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N (3 FLUOROPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N (3,4 DIFLUOROPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N (3,4,5 TRIMETHOXYPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N (4 CHLOROPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N (4 FLUOROPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N (4 TOLYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N (4-FLUORO 3 METHOXYPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N [3 FLUORO 4 (4 METHYLPIPERAZIN 1 YL)PHENYL]CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N [4 (1 METHYL 1H PYRAZOL 4 YL)PHENYL]CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N [4 (1 METHYL 1H PYRAZOL 5 YL)PHENYL]CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N [4 (TRIFLUOROMETHYL)PHENYL]CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N [4 CHLORO 3 [(4 METHYLPIPERAZIN 1 YL)METHYL] PHENYL]CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N [4 [1 (PIPERIDIN 4 YL) 1H PYRAZOL 4 YL]PHENYL]CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N [4 [1 (TETRAHYDRO 2H PYRAN 4 YL) 1H PYRAZOL 4 YL]PHENYL]CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 (5 ACETYLTHIOPHEN 2 YL)PHENYL] N [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL]CYCLOPROPANE 1,1 DICARBOXAMIDE; N [4 [(3 AMINOBENZO[D]ISOXAZOL 4 YL)OXY]PHENYL] N (4 FLUOROPHENYL)CYCLOPROPANE 1,1 DICARBOXAMIDE; N1 [4 (3 AMINOBENZO[D]ISOXAZOL 4 YL)PHENYL] N3 (4 FLUOROPHENYL)MALONAMIDE; SCATTER FACTOR RECEPTOR; UNCLASSIFIED DRUG; UNINDEXED DRUG; ISOXAZOLE DERIVATIVE; PROTEIN KINASE INHIBITOR;

EID: 84921371030     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2014.12.002     Document Type: Article
Times cited : (15)

References (48)
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    • Marcin L.R..1    Thompson, L.A.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.