A cross-sectional observational study of pneumococcal carriage in children, their parents, and older adults following the introduction of the 7-valent pneumococcal conjugate vaccine

Medicine (United States)

Volumn 94, Issue 1, 2015, Pages e335-

  Hamaluba, Mainga ^a   Kandasamy, Rama ^a   Ndimah, Susan ^a   Morton, Richard ^b   Caccamo, Marisa ^a   Robinson, Hannah ^a   Kelly, Sarah ^a   Field, Aimee ^a   Norman, Lily ^a   Plested, Emma ^a   Thompson, Ben A V ^c   Zafar, Azhar ^d   Kerridge, Simon A ^a   Lazarus, Rajeka ^a   John, Tessa ^a   Holmes, Jane ^a   Fenlon, Shannon N ^e   Gould, Katherine A ^e   Waight, Pauline ^e   Hinds, Jason ^e   Crook, Derrick ^f   Snape, Matthew D ^a   Pollard, Andrew J ^a   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b GUY'S AND ST THOMAS' NHS FOUNDATION TRUST   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d NATIONAL HEALTH SERVICE   (United Kingdom)

^e ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

PNEUMOCOCCUS VACCINE; VACCINE;

ADULT; ARTICLE; BACTERIAL COLONIZATION; BACTERIUM ISOLATION; CHILD; CROSS-SECTIONAL STUDY; DISEASE CARRIER; DISEASE SURVEILLANCE; FEMALE; HUMAN; MALE; NOSE SMEAR; OBSERVATIONAL STUDY; PARENT; PNEUMOCOCCAL INFECTION; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT; SEROTYPING; STREPTOCOCCUS; VACCINATION; AGED; DRUG EFFECTS; GENETICS; ISOLATION AND PURIFICATION; MICROBIOLOGY; NASOPHARYNX; PNEUMOCOCCAL INFECTIONS; PRESCHOOL CHILD; SEROTYPE; STREPTOCOCCUS PNEUMONIAE;

ADULT; AGED; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; NASOPHARYNX; PNEUMOCOCCAL INFECTIONS; SEROGROUP; STREPTOCOCCUS PNEUMONIAE; VACCINES, CONJUGATE;

EID: 84921367887     PISSN: 00257974     EISSN: 15365964     Source Type: Journal    
DOI: 10.1097/MD.0000000000000335     Document Type: Article

References (40)

1. OBrien KL, Wolfson LJ, Watt JP, et al. Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates. Lancet. 2009;374:893-902.
2. Koedel U, Scheld WM, Pfister HW. Pathogenesis and pathophysiology of pneumococcal meningitis. Lancet Infect Dis. 2002;2:721-736.
3. WHO Publication. Pneumococcal vaccines WHO position paper-2012-recommendations. Vaccine. 2012;30:4717-4718.
4. Mufson MA, Stanek RJ. Bacteremic pneumococcal pneumonia in one American City: a 20-year longitudinal study, 1978-1997. Am J Med. 1999;107 (1A):34S-43S
5. Koivula I, Sten M, Makela PH. Prognosis after community-Acquired pneumonia in the elderly: a population-based 12-year follow-up study. Arch Intern Med. 1999;159:1550-1555.
6. Sleeman KL, Daniels L, Gardiner M, et al. Acquisition of Streptococcus pneumoniae and nonspecific morbidity in infants and their families: a cohort study. Pediatr Infect Dis J. 2005;24:121-127.
7. Bogaert D, Sluijter M, Toom NL, et al. Dynamics of pneumococcal colonization in healthy Dutch children. Microbiology. 2006;152 (pt 2):377-385.
8. Ridda I, Macintyre CR, Lindley R, et al. Lack of pneumococcal carriage in the hospitalised elderly. Vaccine. 2010;28:3902-3904.
9. Mackenzie GA, Leach AJ, Carapetis JR, et al. Epidemiology of nasopharyngeal carriage of respiratory bacterial pathogens in children and adults: cross-sectional surveys in a population with high rates of pneumococcal disease. BMC infectious diseases. 2010;10:304.
10. Turner P, Turner C, Jankhot A, et al. A longitudinal study of Streptococcus pneumoniae carriage in a cohort of infants and their mothers on the Thailand-Myanmar border. PLoS One. 2012;7:e38271.
11. Nuorti JP, Butler JC, Crutcher JM, et al. An outbreak of multidrugresistant pneumococcal pneumonia and bacteremia among unvaccinated nursing home residents. N Engl J Med. 1998;338:1861-1868.
12. Slack M, Krahe D. Cluster of Serotype 5 Invasive Pneumococcal Disease in a Religious Community in North London. Presented at 6th International Symposium on Pneumococci and Pneumococcal Diseases June 8 to 12, 2008, Reykjavik, Iceland, (poster presentation)2008.
13. Principi N, Marchisio P, Schito GC, et al. Risk factors for carriage of respiratory pathogens in the nasopharynx of healthy children. Ascanius Project Collaborative Group. Pediatr Infect Dis J. 1999;18:517-523.
14. Davis SM, Deloria-Knoll M, Kassa HT, et al. Impact of pneumococcal conjugate vaccines on nasopharyngeal carriage and invasive disease among unvaccinated people: review of evidence on indirect effects. Vaccine. 2013;32:133-145.
15. Brueggemann AB, Peto TE, Crook DW, et al. Temporal and geographic stability of the serogroup-specific invasive disease potential of Streptococcus pneumoniae in children. J Infect Dis. 2004;190:1203-1211.
16. Nurhonen M, Cheng AC, Auranen K. Pneumococcal transmission and disease in silico: a microsimulation model of the indirect effects of vaccination. PLoS One. 2013;8:e56079.
17. Pneumococcal serotype distribution for samples referred for serotyping epidemiological years (July-June): 2000/1-2005/6. 2009. http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/Pneumococcal/EpidemiologicalDataPneumococcal/BackgroundEpidemiologyPneumococcal/IPDTables/pneumoPneumococcalSerotypeDistribution. Accessed on 21st May 2013.
18. Percentage of total number of cases of invasive pneumococcal disease (IPD) serotypes in the 7-valent vaccine for under 5 year olds and all ages for epidemiological year: July 2002-June 2006. 2008. http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/Pneu mococcal/EpidemiologicalDataPneumococcal/BackgroundEpidemio logyPneumococcal/IPDGraphs/pneumoPercentageTotalNumberIP DUnder5s0206. Accessed on 21st May 2013.
19. Sjostrom K, Spindler C, Ortqvist A, et al. Clonal and capsular types decide whether pneumococci will act as a primary or opportunistic pathogen. Clin Infect Dis. 2006;42:451-459.
20. Cumulative weekly number of reports of Invasive Pneumococcal Disease due to any of the seven serotypes in Prevenar 7: children aged 2 to 4 years in England and Wales by epidemiological year: July-June (2005-to date). 2013. http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/Pneumococcal/EpidemiologicalDa taPneumococcal/CurrentEpidemiologyPneumococcal/InPrevenar7/pneumo02Cummulativeweekly24inPrevenar7. Accessed on 21st May 2013.
21. Miller E, Andrews NJ, Waight PA, et al. Herd immunity and serotype replacement 4 years after seven-valent pneumococcal conjugate vaccination in England and Wales: an observational cohort study. Lancet Infect Dis. 2011;11:760-768.
22. Hammitt LL, Bruden DL, Butler JC, et al. Indirect effect of conjugate vaccine on adult carriage of Streptococcus pneumoniae: an explanation of trends in invasive pneumococcal disease. J Infect Dis. 2006;193:1487-1494.
23. Lexau CA, Lynfield R, Danila R, et al. Changing epidemiology of invasive pneumococcal disease among older adults in the era of pediatric pneumococcal conjugate vaccine. JAMA. 2005;294:2043-2051.
24. Kaye P, Malkani R, Martin S, et al. Invasive Pneumococcal Disease (IPD) in England & Wales after 7-valent conjugate vaccine (PCV7); potential impact of 10 and 13-valent vaccines. 2009. http://www.hpa. org.uk/webc/HPAwebFile/HPAweb-C/1245581527892. Accessed on 21st May 2013.
25. OBrien KL, Nohynek H. Report from a WHO Working Group: standard method for detecting upper respiratory carriage of Streptococcus pneumoniae. Pediatr Infect Dis J. 2003;22:e1-e11.
26. Turner P, Hinds J, Turner C, et al. Improved detection of nasopharyngeal cocolonization by multiple pneumococcal serotypes by use of latex agglutination or molecular serotyping by microarray. J Clin Microbiol. 2011;49:1784-1789.
27. Newton R, Hinds J, Wernisch L. Empirical Bayesian models for analysing molecular serotyping microarrays. BMC Bioinformatics. 2011;12:88.
28. Trotter CL, Waight P, Andrews NJ, et al. Epidemiology of invasive pneumococcal disease in the pre-conjugate vaccine era: England and Wales, 1996-2006. J Infect. 2010;60:200-208.
29. Bogaert D, van Belkum A, Sluijter M, et al. Colonisation by Streptococcus pneumoniae and Staphylococcus aureus in healthy children. Lancet. 2004;363:1871-1872.
30. Hussain M, Melegaro A, Pebody RG, et al. A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting. Epidemiol Infect. 2005;133:891-898.
31. Jounio U, Juvonen R, Bloigu A, et al. Pneumococcal carriage is more common in asthmatic than in non-Asthmatic young men. Clin Respir J. 2010;4:222-229.
32. Balmer P, Borrow R, Findlow J, et al. Age-stratified prevalences of pneumococcal-serotype-specific immunoglobulin G in England and their relationship to the serotype-specific incidence of invasive pneumococcal disease prior to the introduction of the pneumococcal 7-valent conjugate vaccine. Clin Vaccine Immunol. 2007;14:1442-1450.
33. Invasive pneumococcal disease incidence rate per 100,000 population by age grouping England and Wales, 1996-2005. 2008. http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/Pneumococcal/EpidemiologicalDataPneumococcal/BackgroundEpidemiologyP neumococcal/IPDGraphs/pneumoIPDIncidenceRate/. Accessed on 21st May 2013.
34. Devaster JM, Leroux-Roels I, Leroux-Roels G, et al. Inferior humoral response in elderly versus young adults to the 23-valent polysaccharide vaccine. In: Program and abstract book of the 5th International Symposium on Pneumococci and Pneumococcal Diseases; April 2 to 6, 2006; Alice Springs, Australia; p244.
35. Cumulative weekly number of reports of Invasive Pneumococcal Disease due to any of the serotypes NOT IN Prevenar13TM: Children aged 2 to 4 years in England and Wales by epidemiological year: July-June (2005-to date). 2013. http://www.hpa.org.uk/Topics/InfectiousDiseases/InfectionsAZ/Pneumococcal/EpidemiologicalDa taPneumococcal/CurrentEpidemiologyPneumococcal/NotInPreve nar13/pneumo05Cummulativeweekly24NOTINPrevenar13vacc/. Accessed on 21st May 2013.
36. Hsu KK, Shea KM, Stevenson AE, et al. Underlying conditions in children with invasive pneumococcal disease in the conjugate vaccine era. Pediatr Infect Dis J. 2011;30:251-253.
37. Flasche S, Van Hoek AJ, Sheasby E, et al. Effect of pneumococcal conjugate vaccination on serotype-specific carriage and invasive disease in England: a cross-sectional study. PLoS medicine. 2011;8:e1001017.
38. Sleeman KL, Griffiths D, Shackley F, et al. Capsular serotypespecific attack rates and duration of carriage of Streptococcus pneumoniae in a population of children. J Infect Dis. 2006;194:682-688.
39. Huang SS, Hinrichsen VL, Stevenson AE, et al. Continued impact of pneumococcal conjugate vaccine on carriage in young children. Pediatrics. 2009;124:e1-e11.
40. Meeting of the Strategic advisory group of experts on immunization, November 2011-conclusions and recommendations. Wkly Epidemiol Rec. 2012;87:1-16http://www.who.Int/wer. Accessed on 20th October 2013.