Oxygenase-catalyzed desymmetrization of N,N-dialkyl-piperidine-4-carboxylic acids

Angewandte Chemie - International Edition

Volumn 53, Issue 41, 2014, Pages 10925-10927

  Rydzik, Anna M ^a   Leung, Ivanhoe K H ^a   Kochan, Grazyna T ^b   McDonough, Michael A ^a   Claridge, Timothy D W ^a   Schofield, Christopher J ^a,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c Instituto de Investigación Sanitaria de Navarra   (Spain)

Author keywords

biocatalysis; C H activation; desymmetrisation; oxygenases; butyrobetaine hydroxylase

Indexed keywords

ACTIVATION ANALYSIS; BIOCHEMISTRY; BIOSYNTHESIS; CARBOXYLATION; HYDROXYLATION;

BIOCATALYSIS; C-H ACTIVATION; DESYMMETRISATION; HYDROXYLASES; OXYGENASES;

CATALYSIS;

CARBOXYLIC ACID; CARNITINE; GAMMA BUTYROBETAINE DIOXYGENASE; PIPERIDINE; PIPERIDINE DERIVATIVE;

BIOCATALYSIS; BIOSYNTHESIS; CHEMISTRY; ENZYME ACTIVE SITE; METABOLISM; OXIDATION REDUCTION REACTION; STEREOISOMERISM;

BIOCATALYSIS; CARBOXYLIC ACIDS; CARNITINE; CATALYTIC DOMAIN; GAMMA-BUTYROBETAINE DIOXYGENASE; OXIDATION-REDUCTION; PIPERIDINES; STEREOISOMERISM;

EID: 84921363915     PISSN: 14337851     EISSN: 15213773     Source Type: Journal    
DOI: 10.1002/anie.201406125     Document Type: Article

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