Adult exposure to bisphenol A (BPA) in Wistar rats reduces sperm quality with disruption of the hypothalamic-pituitary-testicular axis

Toxicology

Volumn 329, Issue , 2015, Pages 1-9

  Wisniewski, Patricia ^a   Romano, Renata M ^a   Kizys, Marina M L ^b   Oliveira, Kelen C ^b   Kasamatsu, Teresa ^b   Giannocco, Gisele ^b   Chiamolera, Maria I ^b   Dias da Silva, Magnus R ^b   Romano, Marco A ^a  

^a State University of Centro Oeste   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Bisphenol A; Gene expression; Gonadotropins; Sperm function; Sperm production; Testosterone

Indexed keywords

4,4' ISOPROPYLIDENEDIPHENOL; ANDROGEN RECEPTOR; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FOLLITROPIN; FOLLITROPIN BETA SUBUNIT; GONADORELIN RECEPTOR; LUTEINIZING HORMONE; LUTEINIZING HORMONE BETA SUBUNIT; TESTOSTERONE; BENZHYDRYL DERIVATIVE; PHENOL DERIVATIVE;

ACROSOME; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; EPIDIDYMIS; ESTRADIOL BLOOD LEVEL; FOLLITROPIN BLOOD LEVEL; GENE EXPRESSION; HYPOTHALAMUS; HYPOTHALAMUS HYPOPHYSIS GONAD SYSTEM; LUTEINIZING HORMONE BLOOD LEVEL; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; SPERM QUALITY; SPERMATOGENESIS; SPERMATOZOON COUNT; TESTOSTERONE BLOOD LEVEL; ANIMAL; BLOOD; DOSE RESPONSE; DRUG EFFECTS; GENETICS; HYPOTHALAMUS HYPOPHYSIS SYSTEM; METABOLISM; MITOCHONDRION; REPRODUCTION; SPERMATOZOON; TESTIS; WISTAR RAT;

RATTUS NORVEGICUS;

ANIMALS; BENZHYDRYL COMPOUNDS; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIDIDYMIS; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; FOLLICLE STIMULATING HORMONE; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; LUTEINIZING HORMONE; MALE; MITOCHONDRIA; PHENOLS; RATS; RATS, WISTAR; RECEPTORS, ANDROGEN; RECEPTORS, LHRH; REPRODUCTION; SPERMATOGENESIS; SPERMATOZOA; TESTIS; TESTOSTERONE;

EID: 84921359039     PISSN: 0300483X     EISSN: 18793185     Source Type: Journal    
DOI: 10.1016/j.tox.2015.01.002     Document Type: Article

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